A Multi-Center Educational Research Regarding Breastfeeding for Pediatrics Residents in Korea

Yong Sung Choi,정성훈,김은선,Eun Sun Kim,Eunhee Lee,Euiseok Jung,So-Yeon Lee,이우령,Hye Sun Yoon,Yong Joo Kim,Ji Kyoung Park,Son Moon Shin,Ellen Ai-Rhan Kim 대한신생아학회 2022 Neonatal medicine Vol.29 No.1

Purpose: Pediatricians have a significant responsibility to educate mothers about the importance of breastfeeding. However, there have been minimal efforts in the courses of resident training in Korea. The purpose of this study is to evaluate the change in knowledge and attitude before and after a 4-week breastfeeding educational intervention among multicenter residents. Methods: Prospective interventional educational research was designed for residents at eight training hospitals in Korea. Institutional reviews were obtained in each hospital. The education curriculum consisted of 14 courses regarding breastfeeding theory and practice. These materials were used to teach pediatric residents for 4 weeks. Knowledge-based tests were administered before the course, and re-tests were administered after the course using different test items of similar levels. Test scores and survey responses were compared before and after the intervention. Results: A total of 73 residents (1st year 20, 2nd year 23, 3rd year 16, and 4th year residents 14) from eight training hospitals completed the intervention. Their average age was 30.3±2.9 years, 17 (23.3%) were male, 22 (30.1%) were married, and eight had more than one child of their own. The mean pre-test score was 61.8±13.4 and the mean post-test score was 78.3±7.5 (P<0.001). The inter-grade difference in the score was significant in the pre-test (P=0.005), but not significant in the post-test (P=0.155). There were more responses of obtaining confidence after the intervention (P<0.001). Conclusion: In our study, pediatric residents showed improvement in their knowledge and confidence level after 4 weeks of the breastfeeding curriculum. This will provide a basis for future policymaking in the training of pediatric residents regarding breastfeedReceived: 6 January 2022 Revised: 15 February 2022 Accepted: 15 February 2022 Correspondence to: Ellen Ai-Rhan Kim, MD Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea Tel: +82-2-3010-3390 Fax: +82-2-3010-6978 E-mail: arkim@amc.seoul.kr A Multi-Center Educational Research Regarding Breastfeeding for Pediatrics Residents in Korea Yong-Sung Choi, MD,PhD1, Sung-Hoon Chung, MD, PhD2, Eun Sun Kim, MD, PhD3, Eun Hee Lee, MD4, Euiseok Jung, MD5, So Yeon Lee, MD, PhD5, Wooryoung Lee, MD6, Hye Sun Yoon, MD, PhD7, Yong Joo Kim, MD, PhD8, Ji Kyoung Park, MD, PhD9, Son Moon Shin, MD, PhD9, and Ellen Ai-Rhan Kim, MD, PhD5 1Department of Pediatrics, Kyung Hee University Hospital, Seoul, Korea 2Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, Korea 3Department of Pediatrics, Kangwon National University Hospital, Chuncheon, Korea 4Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea 5Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 6Department of Pediatrics, Soonchunhyang University Seoul Hospital, Seoul, Korea 7Department of Pediatrics, Nowon Eulji Medical Center, Eulji University, Seoul, Korea 8Department of Pediatrics, Hanyang University Seoul Hospital, Seoul, Korea 9Department of Pediatrics, Inje University Busan Paik Hospital, Busan, Korea Neonatal Med 2022 February;29(1):28-35 https://doi.org/10.5385/nm.2022.29.1.28 pISSN 2287-9412 . eISSN 2287-9803 Copyright(c) 2022 By Korean Society of Neonatology This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Original Article 29 Neonatal Med 2022 February;29(1):28-35 https://doi.org/10.5385/nm.2022.29.1.28 ing in Korea.

토양칼럼을 이용한 초기우수 중 염양염류의 수변녹지 토양에서의 제거도 평가

윤석표,최지용 한국물환경학회 2004 한국물환경학회지 Vol.20 No.3

To investigate removal effects of nutrients in stormwater runoff by soil of riparian protection zone, soil column experiment was conducted for 20 months. Artificial stormwater runoff containing phosphate and nitrate was applied on the surface of soil column twice a week, and phosphate and nitrate concentrations were measured from the leached water. Soil of riparian protection zone reduced the released amount of infiltrated water to the surrounding water. After infiltration of 1m depth of soil column, average removal rates of phosphate and nitrate were 97.7% and 74.7%, respectively. As main mechanisms of phosphate are adsorption to soil particle and utilization by plants, periodical replacement of soil and harvesting of plant at the end of growing season are required. For the removal of nutrients in stormwater runoff by the soil layer, soil of riparian protection zone has higher hydraulic conductivity to infiltrate stormwater. Sandy soil having hydraulic conductivity of about 1?0^(-2)㎝/s range might be appropriate for this purpose.

Ni-ZnFerrite의 磁氣的 特性에 미치는 燒結온도의 영향

尹志洪,朴奎殷,金奎用 제주대학교 1982 논문집 Vol.14 No.-

Ni-Zn Ferrite는 1200℃이상의 온도에서는 소결성이 좋으며 Bi₂O₃를 첨가하여 소결한 것은 1250℃에서 최대투자율 2050을 얻었으며 보자력은 0.13 Oe로서 가장 낮은 값을 나타내었다. 그러나 주파수에 따른 초투자율은 높은 주파수 영역에서는 다른 조건에서 소결시킨 시료에 비하여 낮은 값을 가진 것으로 나타났다. 사용되는 주파수의 영역에 따라서 적절한 소결온도, 적절한 첨가물이 결정될 수 있을 것으로 예상된다. The magnetic properties of Ni-Zn ferrites with additive(Bi₂O₃;0.3wt%)and without additive have been measured. The maximum permeability is 2050, the initial permeability is 1538 at 1.55MHz and the coersive force is 0.130Oe.

만 5세 유아들의 쌓기놀이에서 수행된 수학활동에 대한 문화기술적 연구

국지윤,홍용희 이화여자대학교 교과교육연구소 2006 교과교육학연구 Vol.10 No.2

본 연구는 유아들이 쌓기놀이에서 수행하는 수학활동 내용과 수학활동에 영향을 미치는 요인을 알아보기 위하여 만 5세 유아들의 쌓기놀이를 문화기술적 연구방법을 통하여 고찰하였다. 연구 결과 유아들은 쌓기놀이에서 분류, 서열, 수세기, 전체와 부분, 측정, 공간과 기하, 패턴 등의 수학 활동을 수행하였다. 쌓기놀이에서 나타난 각각의 수학활동은 상황에 따라 매우 다양하고 복합적인 형태로 나타났다. 유아의 수학활동에 영향을 주는 요인으로는 수학적인 배율로 제작된 놀이감의 특징, 놀이주제, 성별, 또래참여, 교사개입 등으로 나타났다. 본 연구는 쌓기놀이 영역뿐만 아니라 여러 흥미영역에서의 유아수학활동 및 이에 영향을 미치는 요인에 대한 관심과 연구의 필요성을 시사해준다. This study investigated the contents of math activity carried out by young children in block-play and the factors influencing on their math activity through ethnographic research methodology. The study shows that young children conducted various math activities: classification, order, counting, whole and parts, estimation, space and geometry, and pattern. Each one of the math activities was appeared to be diverse and compound in terms of format according to situations. The factors influencing on young children's math activity were the characteristics of block-play materials made out of mathmatical magnification, block-play themes, gender, peers' participation, and teachers' intervention. The results suggest that further research on the contents of math activity conducted by young children and the factors influencing on math activity at the other interest areas as well as the block-play area are needed.

한국산 자리공 자리공 열매의 적색소를 이용한 식용색소 : Ⅱ. 활성 사포닌을 제거한 색소의 안정성과 가공적성 Ⅱ. Color Stability and Characteristics as Food Colorant of Saponin-Free Pokeberry Pigments

박용석,서지연,황혜정,박기환,윤광로 中央大學校 食糧資源硏究所 2003 食糧資源硏究所 論文集 Vol.15 No.1

우리나라산 자리공 열매의 색소 함량은 산지에 따라 건물 g당 48.56에서 62.16mg으로 천연색소 자원으로 높은 편이였으며 산지간의 격차가 크지 않아 자원성이 좋은 편이었ㄷ. 자리공 열매의 적색소를 absolute ethanol 침전법으로 분획하는 과정에서 활성 사포닌이 95% 이상 제거되며 이 색고 침전물을 silica gel column이나 Sephadex G-25 column으로 정제함으로서 색소의 순도를 높일 수 있었다. Absolute ethanol 처리와 column 정제법을 응용하여 활성 사포닌을 제거 한 실험용 자리공 열매색소 분획 모두 색소 안정성이나 가공적성에서 뚜렷한 차리를 보이지 않았다. 따라서 absolute ethanol만 처리한 색소제품이나 이를 column chromatography로 정제한 색소분획 모두 고순도의 천연색소 첨가물로의 응용 가능성은 분명하였다. 이들 활성 사포닌을 제거한 자리공 열매색소의 색소안정성과 가공적성은 다음과 같이 요약 할 수 있다. 즉, pH 안정범위는 4.8-6.0이었으며, 열에 대한 안정성을 조사한 결과는 4℃에서 45일 저장했을 때는 70%의 색소 잔존율을 나타낼 정도로 안정한 편이었지만 25℃에서는 10일째에서 70% 잔존율을, 50℃이상의 온도에서는 수 시간 정도에서 50%이하의 색소 잔존율을 보여 전반적으로 열 안정성은 불량한 편이었다. 한편 이들의 존재 하에서는 급격한 변색이 진행되었다. 자리공열매 색소에 대하여 ascorbic acid나 palmityl ascorbate의 첨가는 색소 잔존율에 큰 영향을 미치지 않았으며 chlorogenic acid, resocinol 그리고 catechin의 첨가도 마찬가지였다. 포도당, 과당, 맥아당, 설탕, 펙틴, 셀루로스 그리고 cyclodextrin 등의 탄수화물도 전혀 영양을 미치지 않았다. 1000ppm 이내의 EDTA나 citric acid, malic acid 또는 oxalic acid 등의 산도 미치지 않았다. 금속이온으로서, Ca^(2+)과 Al^(3+)의 첨가는 색소의 잔존율에 큰 영향을 미치지 않았으나, Cu^(2+)나 Fe^(2+)의 첨가는 심한 변색을 초래하였다. 자리공 열매즙의 무수 알코올 처리물(적색 색소 침전물)은 soft gel, firm gel 또는 캔디 등의 고형 식품에 잘 어울리고, 음료에서는 변색이 빠르게 진행되며, 특히 요구르트의 경우가 가장 민감하였다. 결론적으로 보면, 우리나라산 자리공 열매에서 활성 사포닌을 제거하고 확보한 색소제품은 사탕무의 betanin과 거의 같은 색소안정성과 가공적성을 보여 줌으로서 사탕무색소 첨가제인 beet red를 대신할 수 있으며 색소의 함량이나 순도라는 관점에서는 훨씬 우수할 것으로 사료된다. To evaluate the basic data on the color stabilities of saponin-free pokeberry pigment products, % remain of pigment were calculated from absorbances of solutions stored at various conditions. The pigment products were estimated to be very stable at pH 4.8-6.0. Thermostability of pH 5.0 solution of pigment products could be kept stable below 4℃. Addition of Cu2+ or/and Fe2+ decreased the % remain of pigment, whereas most food components had no offset the stability of pokeberry pigment. The color changes of some model foods having pokeberry pigment were checked by Hunter color differerence meter for 45 days. In solid foods like gels and candy the changes of color difference were very slower than that of model beverages. Application of pokeberry pigment to soft drink and yogurt were found to be effective at the refrigerated condition.

후두 및 하인두 편평세포암종에서 E-cadherin의 면역조직화학적 발현

도남용,나한조,이도용,허준,최지윤,이홍영,임성철 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Background and Objectives : The cell-cell adhesion molecule E-cadherin is necessary for the maintenance of the epithelial cellular structure. We were designed to confirm the significance of E-cadherin as a marker for differentiation and invasiveness of squamous cell carcinoma of the larynx and hypopharynx. Materials and Methods : Our study was investigated for the immunohistochemical expression of the epithelium-specific cell adhesion molecule E-cadherin in formalin fixed paraffin embedded tissue specimen of 32 cases of squamous cell carcinoma of larynx and hypopharynx. Results : The positive expression of E-cadherin was 56.3%(18 cases) in squamous cell carcinoma of the larynx and hypopharynx. Decreased E-cadherin expression was a stastistically significant correlation with a increased grade of lymph node stage and clinical stage. Reduced expression was seen in the large tumor size and poorly differentiated tumors, but these result was not statistically significant. Conclusion : The expression of E-cadherin may be related with progression of squamous cell carcinoma of the larynx and hypopharynx. But these correlation were not sufficient for the prognostic indicators in squamous cell carcinomas of the larynx and hypopharynx.

高效率을 갖는 Al-MIS型 太陽電池 製作과 特性

金奎用,尹志洪 제주대학교 1982 논문집 Vol.14 No.-

비저항이 10∼15Ω·cm 이고, 결정면이 (1 1 1)인 p-Si 기판위에 산회막 SiO₂를 형성시키고, 그 위에 Schottky barrier 금속으로써 Al을 증착시킨 후 MIS형 solar cell을 제작하였다. 여기서 Si-wafer의 세척과정이나, 열처리를 잘하면 상당히 좋은 정류특성을 가진 diode를 만들 수 있다는 가능성이 있음을 본 실험을 통해서 알 수 있다. 또 Si 경계면에서의 광반사를 방지하고 되도록 많은 입사광선을 흡수하도록 하기 위하여 무반사막으로 Si O를 사용하였는데, 이것을 약 700Å정도 증착함으로써 단락전류가 약 50%정도 증가하였다. AMl 상태의 태양광선 모의장치 아래서 이 태양전지는 개방전압 Voc는 0.45V, 단락전류 Isc는 27.2 mA, 충실도 FF가 0.7, 그리고 energy 변환효율 η가 8.8였다. 앞으로 Si-wafer의 세척방법과 산화막을 균일하게 형성시키는 과정이 개선되면 보다 간편하고, 저렴하게 energy 변환효율을 높일 수 있는 solar cell 제작이 가능할 것이다. A study of experimental date an Al-oxide-p-Si solar cells has led to a metal evaporation procedure which gives open circuit voltage Voc=0.45V, short circuit current Isc=27.2mA/㎠, and fill factor FF=0.7under AM1.(98mw/㎠). Al-MIS solar cells having 1 ㎠ area have been fabricated to produce 8.8% high efficiency on single cystal(1 1 1),10∼15 Ω·cm, and p-type.

한국인에서 Quadruplex PCR을 이용한 8종류 상염색체 STR 유전좌의 다형성 분석

장영길,김기범,신창호,이숭덕,이윤성,이정빈 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

Two quadruplex PCR reactions were designed for 7 tetrameric (D3S2406, D4S2368, D5S818, D7S821, D9S925, D13S317, D19S253) and one trimeric (D6S1043) short tandem repeats loci to study the allele frequency and the applicability of genetic variation in these loci in forensic case works. For 310 unrelated Koreans DNA was isolated from peripheral blood using phenol/chloroform method. Quadruplex I was consisted of D4S2368, D6S1043, D7S821, D9S925 and quadruplex II D3S2406, D5S818, D13S317, D19S253. The amplified products were analyzed by 5% polyacrylamide gel electrophoresis followed by silver staining. The heterozygosity in each loci ranged 92.91-66.13%, and PD(Power of Discrimination) was above 085 in each loci. Every loci except D6S1043 followed hardy-Weinberg expectation. The cumulative PI was low as 1.65×10-10. Two mutations were noted, one in D19S253 and the other in D9S925 among 234 gametes. With these results above eight STR loci studied here preyed to be highly polymorphic enough to be used in forensic field. This study provides valuable population data in these loci for Korean.

방사선치료를 받은 후두암 환자의 특성 및 치료 결과

오윤경,장지영,도남용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Pmpose: To present the characteristics and treatment outcome of laryngeal cancer patients who were treated by radiation therapy with or without surgery and chemotherapy. Materials and Melhods: A total of 23 patients with laryngeal cancer treated from 1998 through 2003 were available for analysis. The primary site of the cancer was the glottis in 12 patients, the supraglottis in 10 patients, and the subglottis in 1 patient. The stages were Ⅰ in 7 patients (30%), Ⅱ in 5(22%), Ⅲ in 3(13%), IV in 6(26%), and recurrent in 2(9%). The minimum follow-up period in surviving patients is 3 years after the radiation therapy. They were treated by radiation therapy at least 44 Gy with or without surgery and chemotherapy. Results: The overall survival at 1, 2, 3, 5 years in total patients were 95.6%, 82.6%, 78.2%, 73.9%. The overall survival at 1, 2, 3, 5 years in the glottic cancer patients were 100%, 100%, 91.6%, 91.6%. The overall survival at 1, 2, 3, 5 years in the supraglottic cancer patients were 90%, 70%, 70%, 60%. The 3-year overall survival showed the significant difference according to the primary site (glottic vs. supraglottic), cervical lymph node status (negative vs. positive), and overall time of radiation therapy (<50 days vs. 50-59 days vs. ≥60 days), Conclusion: The overall survival rate of laryngeal cancer patients in this analysis seems to be similar in early glottic cancers and relatively good in supraglottic cancers as compared with the results of other studies even though the total number of patients is small.

혈액투석 환자에게서 발생한 재생불량성 빈혈 1예

정지용,윤나라,강대웅,오종찬,장재현,선길홍,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Aplastic anemia is a disease characterized by pancytopenia in the peripheral blood and hypocellular bone marrow with the fatty infiltration. The causes of the acquired aplastic anemia were usually related to drugs and immune-related diseases. A 34-years old man was admitted due to general weakness. He has been going hemodialysis for 2 years because of end stage renal disease (ESRD) due to chronic glomerulonephritis. At admission, laboratory tests showed hemoglobin 6.2 g/dL, hematocrit 18.0 %, WBC 5,710mm (neutrophil 71.8%, lymphocyte 19.1%, monocyte 5.9%), reticulocyte 1.9%, platelet 93,000/mm, Fe 12.8 ug/dL, TIBC 204 ug/dL, ferritin 941.47 ng /ml, haptoglobin 0.72 g/L, vitamin B12 508.17 pmol/L, folate 24 ng/mL, total protein 6.54 g/dL, albumin 3.76 g/dL, Alk. pohsphatase 79 IU/L, AST 30.0 IU/L, ALT 39.7 IU/L, total bilirubin 0.57 mg/dl, BUN 79.4 mg/dl and creatinine 10.18 mg/dl. Peripheral blood smear showed the normocytic normochromic anemia with anisocytosis. Anemia was diagnosed but it was irresponsive to the recombinant human erythropoietin (EPO) and blood transfusion. In the bone marrow aspiration smear were there the hypoplastic myeloid and erythroid precursors. The bone marrow biopsy section showed the hypoplasia of all components (10-20%) and the fatty infiltration. We have experienced one case of the idiopathic aplastic anemia in a patient going through hemodialysis and we just report it with documentary records. 저자들은 혈액 투석 중인 환자에서 약물, 면역계 이상등의 원인을 발견할 수 없었음에도 재생 불량성 빈혈이 발생한 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.