Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction

( Joon Young Kim ),( Myung Ho Jeong ),( Yong Woo Choi ),( Yong Keun Ahn ),( Shung Chull Chae ),( Seung Ho Hur ),( Taek Jong Hong ),( Young Jo Kim ),( In Whan Seong ),( In Ho Chae ),( Myeong Chan Cho ) 대한내과학회 2015 The Korean Journal of Internal Medicine Vol.30 No.6

Background/Aims: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to evaluate the temporal trends and in-hospital outcomes of primary PCI in nonagenarian STEMI patients. Methods: We retrospectively reviewed data from the Korea Acute Myocardial Infarction Registry (KAMIR) from November 2005 to January 2008, and from the Korea Working Group on Myocardial Infarction (KorMI) from February 2008 to May 2010. Results: During this period, the proportion of nonagenarians among STEMI patients more than doubled (0.59% in KAMIR vs. 1.35% in KorMI), and the rate of use of primary PCI also increased (from 62.5% in KAMIR to 81.0% in KorMI). We identified 84 eligible study patients for which the overall in-hospital mortality rate was 21.4% (25.0% in KAMIR vs. 20.3% in KorMI, p = 0.919). Multivariate analysis identified two independent predictors of in-hospital mortality, namely a final Thrombolysis in Myocardial Infarction (TIMI) flow < 3 (odds ratio [OR], 13.7; 95% confidence interval [CI], 3.2 to 59.0; p < 0.001) and cardiogenic shock during hospitalization (OR, 6.7; 95% CI, 1.5 to 30.3; p = 0.013). Conclusions: The number of nonagenarian STEMI patients who have undergone primary PCI has increased. Although a final TIMI flow < 3 and cardiogenic shock are independent predictors of in-hospital mortality, primary PCI can be performed with a high success rate and an acceptable in-hospital mortality rate.

가막만에 출현하는 동물플랑크톤의 종조성과 계절별 출현 양상

서호영,이인태,윤양호,최상덕,이삼노,한명일,김병섭,강윤호,이우범 한국환경생물학회 2002 환경생물 : 환경생물학회지 Vol.20 No.2

가막만에 출현하는 동물플랑크톤을 계절별(2001년 4월, 7월, 9월, 12월)로 Norpac네트를 이용하여 수직 채집하였다. 우점적으로 출현한 분류군은 4월과 12월에 요각류, 7월에 요각류와 지각류,9월에 야광충이었다. 출현 개체수는 22~17,197indiv. m^-3으로 시·공간적으로 변동폭이 매우 컸다. 요각류의 우점종은 4월에 Euryte-mora pacifica, Acartio omorii, Cenfropages abdominalis, Colanus sinicus, 7월에 Lobidocera rofunda와 A. erythraea, 9월에 A. eryfhraea와 Paracalanus parvus s. l., 12월에 A. omorii와 E. pacifca로 주로 내만종으로 변하였다. 그러나, 9월에 외양종인 Eucalanus sp.와 Neo-calnus sp. 또한 다수 출현하였다. 이와 같은 출현 경향은 가막만이 폐쇄성 내만임에도 불구하고 동물플랑크톤의 분포 특성은 내만수 이외에 계절적으로 외만수의 영향을 강하게 받고 있음을 암시하고 있다. Zooplankton was sampled vertically with a Norpac net from Gamag Bay in April, July, September and December, 2001. Copepods were predominant in April and December, and cladocerans in July and Noctiluca scintillans in September, respectively. There are high spatio-temporal fluctuations in the abundance of zooplankton with a range of 22∼17,197 indiv./㎥. In the copepod community, neritic species, Eurytemora pacifica, Acartia omorii, Centropages abdominalis and Calanus sinicus were predominant in April; Labidocera rotunda and A. erythraea in July; A. erythraea and Paracalanus parvus s. l. in September; A. omorii and E. pacifica in December. However, oceanic species Eucalanus sp. and Neocalanus sp. were abundant in September. It indicates that although Gamag Bay is semi-closed, the distribution pattern of zooplankton is seasonally strongly affected by oceanic waters in addition to neritic ones.

가곡 스카른 광상 월곡-선곡 광체의 광물.지구화학적 특성: 성인적 의미

최부갑,최선규,서지은,유인걸,강흥석,구민호,Choi, Bu-Kap,Choi, Seou-Gyu,Seo, Ji-Eun,Yoo, In-Kol,Kang, Heung-Suk,Koo, Min-Ho 대한자원환경지질학회 2010 자원환경지질 Vol.43 No.5

가곡 스카른 광상은 고생대 조선누층군 석회질암을 관입한 백악기 화강암체의 접촉부를 따라 층상으로 교대된 광상으로 구성되어 있다. 관계화성암인 반심성암체는 석영몬조암~화강반암 조성과 함께 I형, 칼크-알카리 계열, 고알루미나질 지화학적 특정을 보이며, 가곡 Zn-Pb 광상에서는 내성스카른과 비하여 외성스카른이 광범위하게 배태되어 있다. 선곡과 월곡 지역의 광체에서 지화학적/광물학적 특성은 관계화성암으로부터 근접성에 의하여 좌우되고 있다. 가곡 광산의 섬아연석에는 Mn, Cd, Cu, In 성분이 미량 함유되어 있고, 정출온도 차이 및 분화과정을 통하여 차별화된 농집 과정이 유도됨으로서 광체에 따라 미량원소의 차이를 보이고 있다. 광석 중 높은 In/Zn비와 Cd/Zn비 그리고 섬아연석 중 낮은 Mn/Zn비는 마그마로부터 공급된 근원물질의 근접성과 밀접한 연관성을 보이고 있다. 따라서, 광석과 섬아연석에 함유된 미량원소의 농집 양상은 정출온도와 광화유체의 근원물질과 관련된 광체의 지화학적/광물학적 차별성을 인지할 수 있는 중요한 지시자로 이용될 수 있다. The Gagok stratabound skarn deposit is the result of the intrusion of the Cretaceous granitic pluton into the Paleozoic calcareous rocks. The subvolcanic intrusion ranges in composition from quartz monzonite to granite porphyry with I-type, calc-alkaline and weakly peraluminous characteristics. Both endoskarn and exoskarn are developed at the Gagok Zn-(Pb) deposit, with more exoskarn than endoskarn. Geochemical and mineralogical characteristics in the Seongok and Wolgok orebodies can be treated in terms of self-organization. Sphalerites in the Gagok ore can also incorporate minor amounts of Mn, Cd, Cu and In. Trace element concentrations in different orebodies vary because fractionation of a given element into sphalerite is influenced by formation temperature and the amount of sphalerite in the ore. A group of high In/Zn and Cd/Zn ratios in ores, and low Mn/Fe ratios in sphalerites are correlated with proximal processes of a magmatic source. The pattern of minor/trace element variations in ores and sphalcrites can be used for petrogenetic interprctation, e.g., orebody zonation related to crystallization temperature and fluid d sources.

In-hospital mortality in patients with STEMI admitted during off hours

( Sung-Soo Kim ),( Myung Ho Jeong ),( Jeong Gwan Cho ),( Young Keun Ahn ),( Jong Hyun Kim ),( Shung Chull Chae ),( Young Jo Kim ),( Seung Ho Hur ),( In Whan Seong ),( Taek Jong Hong ),( Dong-hoon Choi 대한내과학회 2013 대한내과학회 추계학술발표논문집 Vol.2013 No.1

Conflicting results exist on the outcome of off hours PCI in ST elevation myocardial infarction (STEMI). However, there were only a few studies that have focused on the clinical characteristics and outcomes of off hours PCI in STEMI. So, we studied the clinical characteristics and hospital mortality in STEMI patients treated with primary PCI during regular hours (weekdays 9:00 AM to 6:00 PM) versus off hours Weekdays 6:01 PM to 8:59 AM, weekends, and holidays) in Korea Acute Myocardial Infarction Registry. We analyzed in hospital and one year mortality among 5,665 consecutive ST segment elevation myocardial infarction patients treated with primary PCI between November 2005 to January 2008. Total 2,848 (50.2%) patients were treated during off hours. Baseline finding were similar, although regular hours patients were older. Median symptom to balloon time (304 min, IQR 175 to 750 vs. 270 min, IQR 145 to 551, p=0.001) were longer for regular hours primary PCI. Median door to balloon time (71min, IQR: 48 to 132 vs. 59 min, IQR 39 to 110 min, p=0.001) were longer for off hours pPCI. Also, Cardiac enzyme such as Max CK-MB (212.1±299.3 vs 194.7±303.4, p=0.031) and max TnI (72.6±239.5 vs. 58.9±94.4, p=0.013) were increased in off hours pPCI. However, unadjusted in hospital (6.0% off hours vs. 6.0% regular hours, p=0.946) and one year cardiac mortality (11.3% off hours vs. 11.7% regular hours, p=0.661) were comparable. In multivariate analysis, off hours primary PCI did not predict an adverse outcome. In conclusion, when primary PCI was performed within an appropriate reperfusion strategy, the clinical effectiveness of either off hours or regular hours pPCI is comparable.

소아 제 2형 당뇨병 환아에서 maturity Onset Diabetes of the Young(MODY) 3의 유병률에 관한 연구

최인경,김덕희,김호성,허남,백상현,정성영 대한소아과학회 2004 小兒科 Vol.47 No.6

Incidence of Adult In-Hospital Cardiac Arrest Using National Representative Patient Sample in Korea

Yuri Choi,In Ho Kwon,정진우,정준영,노영훈 대한의료정보학회 2016 Healthcare Informatics Research Vol.22 No.4

Objectives: This study analyzed the incidence and characteristics of in-hospital cardiac arrest (IHCA) in Korea based on a sample group of patients that is representative of the population. Methods: The incidence of IHCA in adults was extracted from HIRA-NIS-2009, a sample of all patients using medical services in Korea. IHCA patients were analyzed according to gender, age, type of medical institute, and classification under the 6th revision of the Korean Standard Classification of Diseases (KCD-6). In addition, to assess the differences arising from the size of medical institutes, the IHCA incidence was analyzed in relation to the number of inpatient beds. Results: Based on the sample data, the total incidence of IHCA in Korea was found to be 2.46 per 1,000 admissions (95% confidence interval [CI], 2.37–2.55). A higher incidence was found among men at 3.18 (95% CI, 3.03–3.33), compared to women at 1.84 (95% CI, 1.74–1.94). The incidence of IHCA was also higher in hospitals that had more than 600 inpatients beds at 5.40 (95% CI, 5.16–5.66) in comparison to those that had less than 600 inpatients beds at 4.09 (95% CI, 3.76–4.36) (p < 0.001). By primary disease, the incidence was the highest for infectious diseases. Conclusions: We demonstrated that the IHCA incidence based on gender, age, diagnostic group, and number of beds could be analyzed using the insurance claim data from a national representative sample.

수리된 복합레진 수복물의 전달결합강도 연구

최수영,정선와,황윤찬,김선호,윤창,오원만,황인남 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.6

This study was performed to evaluate the interfacial shear bond strength of base (direct and indirect) and repair composites with aging and surface treatment methods. Direct composites resin specimens (Charisma®, Heraeus Kulzer, Germany) were aged for 5 min, 1 hour, 24 hours, and 1 week in 37℃ distilled water before surface treatment, and then divided into five groups: Group 1, grinding; Group 2, grinding and application of bonding agent; Group 3, grinding, etching with 37% phosphoric acid for 30sec, and application of bonding agent; Group 4, grinding, etching with 37% phosphoric acid for 30sec, silane treatment, and application of bonding agent; Group 5, grinding, etching with 4% hydrofluoric acid for 30sec, silane treatment, and application of bonding agent. Indirect composite resin specimens (Artglass®, Heraeus Kulzer, Germany) were aged for 1 week in 37℃ distilled water and divided into seven groups: Group 1 - Group 5, equal to Charisma specimens; Group 6, grinding, etching 37% phosphoric acid for 60sec, silane treatment, and application of bonding agent; Group 7, grinding, etching with 4% hydrofluoric acid for 60 sec, silane treatment, and application of bonding agent. The repair material(Charisma®) was then added on the center of the surface (5mm in diameter, 5mm in height). The shear bond strength was tested and the data was analyzed using one-way ANOVA and the Student-Newman-Keuls test. The following conclusions were drawn. 1. The shear bond strength of Charisma® specimens aged for 1 hour was significantly higher in Group 2 and Group 5 than in Group 1 (p<0.05), and that of Charisma® specimens aged for 1 week was significantly higher in Group 3 and Group 5 than in Group 1 (p<0.05). No significant difference was found in the bond strength of specimens aged for 5 min and 24 hours. 2. In Group 2 of the Charisma® specimens, there was significant difference between the bond strength of 24 hours and that of 1 week (p<0.05). 3. In Group 4 of the Charisma® specimens, the shear bond strength of specimens aged for 24 hours was significantly higher than the others(p<0.05). 4. There was no significant diiference between the shear bond strength of the Artglass® specimens. 5. Most of the Charisma® specimens showed cohesive fractures. Artglass® specimens that were etched with acid(phosphoric or hydrofluoric) for 30 sec showed more cohesive fractures.

Metallic alloy nanoparticle-based fabrication and optical properties of a Cu(In₁ ₋ <i> _x </i>Ga<i> _x </i>)S₂ absorber layer for solar cells

Choi, Yo-Min,Lee, Young-In,Kim, Seil,Choa, Yong-Ho Elsevier 2014 JOURNAL OF ALLOYS AND COMPOUNDS Vol.615 No.-

<P><B>Abstract</B></P> <P>A highly-densified Cu(In<SUB>1</SUB> <SUB>−</SUB> <I> <SUB>x</SUB> </I>Ga<I> <SUB>x</SUB> </I>)S<SUB>2</SUB> (CIGS2) absorber layer was fabricated using copper, indium and gallium (CIG) metallic alloy nanoparticles synthesized by salt-assisted ultrasonic spray pyrolysis (SAUSP) followed by direct thermal reduction. The reduction process in salt matrix minimized aggregation of CIG metallic alloy nanoparticles that have the potential to lead to higher film densification during sulfurization. To optimize the amount of salt, various NaCl/precursor ratios were used for SAUSP and Cu–In metallic alloy nanoparticles with average particle size of 79nm were obtained. The CIGS2 obtained in the present study exhibited a variable band-gap ranging from 1.46 to 2.4eV depending on the Ga/(In+Ga) ratio, which corresponded to the respective bulk materials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CIGS2 absorber is obtained using Cu, In and Ga (CIG) metallic alloy nanoparticles. </LI> <LI> 79nm CIG metallic alloy nanoparticles are obtained by ultrasonic spray pyrolysis. </LI> <LI> CIG metallic alloy nanoparticles improve the CIGS2 film densification. </LI> <LI> The band gap of CIGS2 can be controlled by introducing the desired precursor ratio. </LI> </UL> </P>

1~2기 본태성 고혈압 환자들에서 Imidapril 대 Enalapril의 항고혈압 효과를 평가하기 위한 무작위, 이중맹검 임상시험

최영진,손대원,김용진,이홍자,채인호,김효수,김철호,오병희,이명묵,박영배,채윤식,이영우 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.11

적외선열화상장치를 이용한 Buchanan plugger 표면의 온도상승 분석

최성아,김선호,황윤찬,윤창,오병주,최보영,정우남,정선와,황인남,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

This study was performed to evaluate the temperature rise on various position of the Buchanan plugger, the peak temperature of plugger's type and the temperature change by its touching time of heat control spring. The heat carrier system 'System B' (Model 1005. Analytic Technologies, USA) and the Buchanan's pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200℃ which Dr. Buchanan's "continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. In order to apply heat on the Buchanan's pluggers, the heat control spring was touched for 1, 2, 3, 4 and 5 seconds respectively. The temperature rise on the surface of the pluggers were measured at 0.5 mm intervals from tip to 20 mm length of shank using the infraed thermography (Radiation Thermometer-IR temper, NEC San-ei Instruments, Ltd, Japan) and TH31-702 Data capture software program (NEC San-ei Instruments, Ltd, Japan). Data were analyzed using a one way ANOVA followed by Duncan's multiple range test and linear regression test. The results as follows. 1. The position at which temperature peaked was approximately at 0.5 mm to 1.5 mm far from the tip of Buchanan's pluggers (p<0.001). The temperature was constantly decreased toward the shank from the tip of it(p<0.001). 2. When the pluggers were heated over 5 seconds, the peak temperature by time of measurement revealed from 253.3±10.5℃ to 192.1±3.3℃ in a touch for 1 sec, from 218.6±5.0℃ to 179.5±4.2℃ in a touch for 2 sec, from 197.5±3.0℃ to 167.6±3.7℃ in a touch for 3 sec, from 183.7±2.5℃ to 159.8±3.6℃ in a touch for 4 sec and from 164.9±2.0℃ to 158.4±1.8℃ in a touch for 5 sec. A touch for 1 sec showed the highest peak temperature, followed by, in descending order, 2 sec, 3 sec, 4 sec. A touch for 5 sec showed the lowest peak temperature (p<0.001). 3. A each type of pluggers showed different peak temperatures. The peak temperature was the highest in F type and followed by, in descending order, M type, ML type. FM type revealed the lowest peak temerature (p<0.001). The results of this study indicated that pluggers are designed to concentrate heat at around its tip, its actual temperature dose not correlate well with the temperature which Buchanan's "continuous wave of condensation" technique recommended, and finally a quick touch of heat control spring for 1 sec reveals the highest temperature rise.