관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.

HY 항원 불일치 췌도 이식에 의한 면역 관용의 유도

최승은,박정규 Official Journal of the Korean society for immunol 2004 Immune Network Vol.4 No.1

고출력 다이오드 레이저를 이용한 SKD11 표면 열처리 특성

최성대,정선환,양승철,김잠규 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

An experimental investigation with high power diode laser system was carried out to study the effect of surface heat treatment on the SKD11. The surface heat treatment characteristics of the laser beam were evaluated using hardness tests, optical microscopy, X-ray diffraction and energy dispersive X-ray spectroscopy(EDS). Results indicated that the Hardness were changed by beam size, focal length, feed rates. The micro grain structure was observed retained austenite grain at hardened zone and globular cementite grain at fine grain zone and base metal zone by optical microscopy. The intensive X-ray diffraction patterns of (110)-(200)-(211) was detected on the surface and the hardened surface intensity level was bigger than the unhardened surface. The intensive X-ray diffraction patterns of (110)-(200)-(211) was detected hardened surface and the hardened surface distributed plenty of carbon density than metal zone.

窒素質肥科의 基追肥 施用時期가 이타리안라이그라스의 生育 및 靑草收量과 養分組成에 미치는 影響

崔洙日,崔亨松,陳星桂 又石大學校 1990 論文集 Vol.12 No.-

本 硏究는 冬季休閑畓을 活用한 이타리안 라이그라스의 栽培에 알맞은 窒素質肥料의 基·追肥 施用適期를 알고자 遂行하였던 바 다음과 같은 結果를 얻었다. 1. 窒素基肥施用時期가 늦어질수록 越 草長의 伸長短縮과 靑草收量을 感收시켰고 組蛋白質, 組脂肪, 組灰粉의 含量도 적어 飼料의 質을 低下시켰으며 또한 越冬期 枯死莖 被害와 越冬後의 靑草收量도 減小시켰다. 2. 窒素質肥料의 追肥施用適期 試驗에서도 追肥施用適期가 늦어질수록 生育量 및 追肥施用適期 減小와 節間을 伸長시켰으며 組蛋, 白質, 組脂肪 含量도 적었다. 3. 窒素質肥料의 基追肥 施用適期는 基肥는 播種當日, 追肥는 生育再生後 10日頃이었다. This experiment was carried out to study the effects of different application times on the nitrogen fertilizer, the fresh matter yield and feed efficiency of Italianryegrass under winter cropping on drained paddy field. Plant height, fresh matter yield and content of organic nutrient were decreased. According as the application times of top basal dressing on the nitrogen were late. In the experiment of the application times of top dressing on the nitrogen times of top wintering. Agronomic characters, fresh matter yield, crude protein, crude fat and crude were decreased. According as thd application times of top dressing on the nitrogen fertilizer were late. The optimum application time of nitrogen fertilizer was sowing date in basal dressing and was 10 days after regrowth in top dressing.

미식축구의 필드골(Field Goal) 킥(Kick)에 대한 운동학적 분석

안찬규,김기형,최승방 한국운동역학회 2003 한국운동역학회지 Vol.13 No.1

Ahn, C-G · Kim , K-H · Chol, S-B. A three-dimensional kinematic analysis of the field goal kicking motion in American football. Korean Journal of Sport Biomechanics, Vol. 13,No. 1, pp. 139-153. The purpose of the study was to present technical guidance about the field goal motion of two skilled players and two unskilled players was corried out. The following conclusions were made: 1. In comparison on the total elapsed time of the kicking, there no significant differences between two groups. The progressing time from BP event to impact among experts group, however, took 0.141 second less than that of novices group. 2. The experts group showed right hip rotatier horizontally toward the targeted ball fixing left hip as the axis. On the other hand, the novices group didn't use the left hip as the axis in the kicking motion. 3. At the impact of kicking the ball, regarding with the distance of the ball and the supporting leg, the right and left distance of experts was 3.45cm longer than that of novices, the front and the rear distance of experts was 5.14cm shorter than novices. 4. At the impact, experts' initial velocity of the targeted ball was 5.27% faster than novices', besides experts' incidence angular displacement was 3.78˚ larger than novices'. 5. After BP event, experts showed a stable movement maintaining flexion and extension at left hip joint and knee joint. On the other hand, for novices, the angle of the left lower extremities became larger. 6. Experts showed the efficient flexion and extension of the hip joint and the knee joint during following procedure in the whole event of the kicking motion. At the BP event, the right knee joint angle of novices was 11.46˚ larger than that of experts. However, the duration of the impact event and FT event among, novices had less extension of knee joint than experts. 7. At the 2nd phase, for both of the groups, the angular velocity of the knee joint drastically increased as the angular velocity of hip joint decreased. However, only novices showed the largest negative angular velocity at the impact.

경직성 뇌성마비 환아에서 선택적 후근 절제술 후 운동기능의 변화

이소영,최인성,한재영,정주찬,위정선,오명신,박승진,이삼규,김재휴 全南大醫大 2001 전남의대학술지 Vol.37 No.1

人體에서 分離한 葡萄糖 非醱酵菌의 抗菌劑 耐性에 關한 硏究

李淵台,崔承求,朴哲熙,曺圭鳳 단국대학교 대학원 1991 學術論叢 Vol.15 No.-

This experiment was conducted to classify for the 82 strains of glucose nonfermentative bacteria obtained from K hospital, in 1988, on the biological differentials and to test the resistance reaction on the drugs for those strains. The results were as follows : 1. Eighty two strains were classified into 65 strains of 79.3% of Ps. aeruginosa, 10 strains of 12.2% of Ps. cepacia, and 7 strains of 8.5% of Ac. calcoaceticus as results of 0 F sugar test, oxidase test, and DNase test. 2. It showed that Ps. aeruginosa was coincided with AP, CM, GM, KM, CF, and TC from the disk and MIC methods in the test of resistance reaction to antimicrobial agent, and especially, that AK and TOB KM and GM were observed high resistance reactive from MIC method. Resistnace to antibiotics for Ps. cepacia showed the identical reaction to AP, CB, CM, AK, SPT, CF, TC, TOB, KM and GM were observed high resistance reative from MIC method. Ac. calcoaceticus was identified the same resistance reaction to antibiotics to CB, KM, GM, AK, CF, and TOB, AP, SPT and TC showed high resistance reaction from the disk method. 3. CF and AP were observed the highest resistance reactions among 10 kinds of drugs used in this experiment and following was CM, KM and TC in order. 4. Ps. aeruginosa, Ps. cepacia, and Ac. calcoaeticus showed all multiple resistance reactions in the test of resistance to drugs, and Ps. aeruginosa was identified high resistance reaction to 6 drugs in 24.6%, Ps. cepacia was 9 drugs in 60%, and Ac. calcoaceticus showed resistance reaction to various kinds of drugs. 5. It showed important question in result of these studies that resistance percentage of NFB decreased by optimal antimicrobial selection and effective treatment established from serious antimicrobial treatment.

부신피질 자극호르몬 단독결핍 1례

박경식,이승현,최석영,박태규,이동화,이찬우,정성복,이인규 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

부신피질 자극호르몬 단독결핍은 국내에서 7례만이 보고된 희귀 질환이며 병인 및 경과 등 아직 불분명한 측면이 많다. 이는 질환지체의 희귀성도 있지만 치료후 자연경과에 대한 장기적인 추적검사가 이루어진 경우가 드물기 때문이기도 하다. 저자들은 비특이적인 전신증상을 주소로 내원한 폐경기후의 56세 여자 환자에서 자가면역질환의 증거없이 고프로릭틴혈증을 보인 부신피질 자극호르몬 단독결핍 1례를 경험하고 1년간의 부신피질호르몬 대치요법후 추적검사를 실시하였기에 문헌 고찰과 함께 보고하는 바이다. Isolated ACTH deficiency is a rare disorder which shows secondary adrenal insufficiency with normal states of other pituitary hormones. A 56-year-old postmenopausal woman complaining general weakness and intermittent mental confusion presented negligible serum cortisol and ACTH level with hyperprolactinemia and mild hyponatremia. Rapid ACTH stimulation test did not show significant increase of serum cortisol level. Combined pituitary stimulation test showed negligible response of cortisol and ACTH, and slightly decreased response of prolactin and gonadotropin. But the responses of TSH and GH were normal. There was no evidence of organic pituitary of hypothalamic lesion in brain MRI and antithyroid autoantibody was not detected in serum. After receiving 12 months of glucocorticoid replacement therapy, she skipped the medicine for 3 weeks and we performed follow-up endocrinologic tests. Serum ACTH and cortisol level was also negligible and prolonged ACTH simulation test showed normal response of serum cortisol. CRF stimulation test showed no response of serum ACTH. Basal prolactin level was decreased to near normal and combined pituitary stimulation test showed normal response of prolactin with slightly blunted response of TSH and GH. We concluded that the case was nonautoimmune origined isolated ACTH deficiency which was accompanied by hyperprolactinemia and resultant deficiency of gonadotropin, so we report this case with review of literatures.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.