法令案審査에 관한 몇가지 考察

鄭成福 법조협회 1994 法曹 Vol.43 No.9

결절성 다발동맥염 1예

윤경우,정성복 대한신장학회 1991 Kidney Research and Clinical Practice Vol.10 No.3

Polyarteritis Nodosa (PAN) is one of the systemic necrotizing vasculitis involving predominantly small and medium-sized muscular arteries, which shows variable clinicopathologic appearance according to the size and location of involved vessels. A 35-year-old male patient was admitted to the Department of Medicine, Yeungnam University and diagnosed as classic PAN by angiography. He was treated with 5 days of methylprednisolone pulse therapy followed by oral prednisolone and cyclophosphamide and was also supported by hemodialysis. Bilateral huge hematomas were absorbed and impalpable after four weeks and no more episodes of U.G.I. Bleeding occurred after administration of corticosteroid and cytotoxic drug. In conclusion, the authors report a case of PAN complicated by bilateral renal hematomas, U.G. I. Bleed- ing and acute renal failure with review of literatures.

진달래 꽃잎의 추출물이 심혈관계에 미치는 영향

전준하,정성복,강승호,김영조,심봉섭,이현우,신동구,박종님 영남대학교 기초/임상의학연구소 1991 Yeungnam University Journal of Medicine Vol.8 No.2

초산과 중탄산나트륨 투석액을 이용한 혈액투석의 비교 분석

임종식,윤경우,정성복 대한신장학회 1993 Kidney Research and Clinical Practice Vol.12 No.3

This study was conducted to compare the effects of acetate dialysate and bicarbonate dialysate on ABGA, blood pressure and symptoms which occur during hemodialyses in chronic stable dialysis patients. 26 patients (13 male and 13 female) with chronic renai failure participated in this study. Hemodialyses performed with acetate dialysate hav- ing 37 mEq/L acetate and bicarbonate dialysate having 8 mEq/L acetate and 30 mEq/L bicarbonate. Each blood sample was drawn for ABGA through arterial line of A-V fistula at 0, 1, 2 and 4 hours during hemodialysis. Serum electrolytes changes between 0 hour and 4 hours during hemodialysis were also studied. Blood pressure change and occurrence of symptoms during hemodialysis were observed. The results are as follows. In acetate dialysis group, there was no significant increase of pH at 1 hour compared with that of predialysis, but pH increased significantly after 2 hours. In bicarbonate dialysis group, pH increased significantly 1, 2 and 4 hours compared with those of predialysis. PaCO? increased significantly at 1 hour after hemodialysis in both groups and returned to baseline values at 4 hours. In acetate dialysis, PaO? decreased significantly at 1 hour and 2 hours (p$lt;0.05), but in bicarbonate dialysis it decreased significantly only at 1 hour. HCO, increased significantly from 1 hour after dialysis in both groups. Between acetate and bicarbonate dialysis, pH and HCO?- at 1, 2 and 4 hours were significantly higher in bicarbonate group (p$lt;0.05), but there was no difference in PaCO? all the time. PaO, level was higher at 1, 2 and 4 hours in bicarbonate dialysis compared with those of acetate dialysis without statistical significance. Serum Na^+, K^+, P^-- decreased significantly at 4 hours compared with those of predialysis values. Serum Ca^++ leve@l increased significantly after 4 hours of hernodialysis. Serum electralytes values were not different between acetate and bicarbonate dialysis group. Percent reduction of blood pressure showed greater systolic blood pressure reduction in acetate dialysis compared with that of bicarbonate dialysis, but diastolic blood pressure showed,no statistical difference. Symptoms such as headache, post-dialysis fatigue, nausea, vomiting, dizziness and abdominal pain developed frequently (p$lt;0.05) in acetate dialysate group. In summary we concluded that bicarbonate dialysis corrects metabolic acidosis more rapidly and has less deleterious symptoms and less blood pressure decrement than acetate dialysis does. We also noted that PaO, decrement was milder and shorter in duration in bicarbonate dialysis than in acetate dialysis.

완정방실 차단 환자에서 좁은 QRS파를 갖는 보조적 심박 조율기의 특성

도준영,이정미,김영진,정성복,강승호,박진호,김영조,심봉섭,이현우 대한순환기학회 1992 Korean Circulation Journal Vol.22 No.4

백서에서 출혈성 쇽이 장내세균 전위에 미치는 영향

김봉준,정문관,김태년,정성복,권순욱,최교원,장병익 대한소화기학회 2001 대한소화기학회지 Vol.37 No.3

Background/Aims: The aim of this study was to determine whether bacterial translocation could be demonstrated after experimental hemorrhagic shock in rat and whether translocated bacteria have a pattern of distribution within the major organ system. Methods: Male Sprague-Dawley rats were randomly assigned to hemorrhagic shock group (group I, n=20), sham shock group (group II, n=20) and normal control group (group III, n=15). At 24, 48, 72 hours after shock, rats were sacrificed and bacteria in their major organs were cultured. Results: The incidence of cultured bacteria in group I were highest. In the group I, enteric bacteria were cultured at mesenteric lymph node of 15 rats (75.0%), liver of 10 rats (50.0%), spleen of 4 rats (20.0%), lung of 4 rats (20.0%), portal vein of 4 rats (20.0%). The most common cultured bacterial species was E. coli. The bacterial translocation seemed to increase significantly in lungs at 48 and 72 hours after shock (p$lt;0.05) and cecal mucosal injury occurred after shock. Conclusions: Bacterial translocation was induced in hemorrhagic shock model. The identification of cultured organism in major organs supports the bacterial translocation from gut. Hemorrhagic shock could impair mucosal barrier, which may promote bacterial translocation.

리팜핀에 의한 급성 신부전

이동화,박태규,이재성,김희식,김경현,하영준,정성복,도준영,윤경우 영남대학교 의과대학 1998 Yeungnam University Journal of Medicine Vol.15 No.1

Rifampin is common drug to treat tuberculosis. Rifampin induced acute renal failure, hemolytic anemia and thrombocytopenia is rare and severe complication. We have experienced a case of rifampin induced acute renal failure, hemolytic anemia and thrombocytopenia. Forty-six years old male was suffered from reactivation of pulmonary tuberculosis, and had to medicate antituberculosis drugs including rifampin(600mg/day). Seven years age, antituberdulosis medication were successfully administered to treat pulmonary tuberculosis without any side effects of drugs. But eight days after readministration of rifampin. fever, abdominal pain, vomiting, oliguria, elevated BUN and creatinine were developed. And thrombocytopenia was also identified after administration of rifampin. The patient was recovered slowly after discontinuation of rifampin & intensive medical care. The renal function was normalized at 55 days after cessation of rifampin. The renal pathologic findings were interstitial nephritis and acute tubular necrosis. And, the rifampin dependent antibodies were indentified by indirect antiglobulin test in the presence of rifampin. So we report this case with a brief review of literature.

부신피질 자극호르몬 단독결핍 1례

박경식,이승현,최석영,박태규,이동화,이찬우,정성복,이인규 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

부신피질 자극호르몬 단독결핍은 국내에서 7례만이 보고된 희귀 질환이며 병인 및 경과 등 아직 불분명한 측면이 많다. 이는 질환지체의 희귀성도 있지만 치료후 자연경과에 대한 장기적인 추적검사가 이루어진 경우가 드물기 때문이기도 하다. 저자들은 비특이적인 전신증상을 주소로 내원한 폐경기후의 56세 여자 환자에서 자가면역질환의 증거없이 고프로릭틴혈증을 보인 부신피질 자극호르몬 단독결핍 1례를 경험하고 1년간의 부신피질호르몬 대치요법후 추적검사를 실시하였기에 문헌 고찰과 함께 보고하는 바이다. Isolated ACTH deficiency is a rare disorder which shows secondary adrenal insufficiency with normal states of other pituitary hormones. A 56-year-old postmenopausal woman complaining general weakness and intermittent mental confusion presented negligible serum cortisol and ACTH level with hyperprolactinemia and mild hyponatremia. Rapid ACTH stimulation test did not show significant increase of serum cortisol level. Combined pituitary stimulation test showed negligible response of cortisol and ACTH, and slightly decreased response of prolactin and gonadotropin. But the responses of TSH and GH were normal. There was no evidence of organic pituitary of hypothalamic lesion in brain MRI and antithyroid autoantibody was not detected in serum. After receiving 12 months of glucocorticoid replacement therapy, she skipped the medicine for 3 weeks and we performed follow-up endocrinologic tests. Serum ACTH and cortisol level was also negligible and prolonged ACTH simulation test showed normal response of serum cortisol. CRF stimulation test showed no response of serum ACTH. Basal prolactin level was decreased to near normal and combined pituitary stimulation test showed normal response of prolactin with slightly blunted response of TSH and GH. We concluded that the case was nonautoimmune origined isolated ACTH deficiency which was accompanied by hyperprolactinemia and resultant deficiency of gonadotropin, so we report this case with review of literatures.

지적민원행정의 능률성 제고에 관한 연구

이왕무(Lee Wang Mu),장우진(Jang Woo Jin),정성복(Jung Sung Bok) 한국지적정보학회 2005 한국지적정보학회지 Vol.7 No.2

본 논문은 현행 지적민원행정의 문제점 해결을 위한 기초자료를 제시할 목적으로 우리나라 지적민원행정의 운영 실태를 능률성 측면에서 분석ㆍ평가하여 문제점들을 도출한 다음에 미래지향적인 지적민원행정체계의 구축을 위한 개선방안을 제시하였다. 능률성 측면에서 제시된 대안으로는 지적정보를 총 관리할 수 있는 CIO 직제의 도입과 함께 도면전산화를 서둘러야 하고, 지적민원양의 폭주에 따른 행정서비스 기능의 질적 저하를 방지하기 위한 전문인력의 확보와 함께 기존 지적직 공무원과 지적공사 민원담당 직원에 대한 재교육과 훈련을 제도적으로 개선할 것을 제안하였다. In this paper, the conditions of operation in the cadastral civil affairs administration in our country were analyzed and evaluated in the view of efficiency to show the basic data for solution of these problems and then the methods for improving the construction of cadastral civil affairs administration system for the future were suggested. The suggested methods in the view of efficiency included the introduction of CIO system which can manage all the cadastral information and the prompt computerization of blue prints. Also it was suggested that hiring more experts in cadastre should be taken to prevent the deterioration of administration service caused by the increase of cadastral civil affairs and that reeducation and training for cadastral civil servants and staffs in charge of civil affairs in the Korea cadastral Survey corporation should be improved systematically.

당뇨병성 심혈관계 자율신경병증 환자에서 Corrected QT 간격 연장에 관한 연구

박종선(Jong Seon Park),이찬우(Chan Woo Lee),전준하(Jun Ha Jeun),정성복(Seong Pok Cheong),원규장(Kyu Chag Won),이충기(Choong Ki Lee),현명수(Myung Soo Hyun),최수봉(Soo Bong Choi),이현우(Hyun Woo Lee),이인규(In Kyu Lee) 대한내과학회 1992 대한내과학회지 Vol.43 No.1

N/A Background: Diabetic cardiac autonomic neuropathy may result in sympathetic imbalance and QTc interval prolongation, predisposing these patients to arrhythmias and sudden death. A simple method for evaluating alterations in cardiac sympathetic innervation may be measurement of the QTc interval. We investigated the relations between QTc interval and diabetic cardiac autonomic neuropathy. Methods: Fifty five patients with type-II diabetics were separated into 4 groups based on the presence and degree of cardiac autonomic neuropathy (CAN) with noninvasive cardiovascular autonomic reflexes and blood pressure response. None of the patients had evidence of ischemic heart disease, or the idiopathic long QT interval syndrome. The corrected QT interval (QTc) was determined at rest with Bazett`s formula. Results: Diabetic patients with ³ 1 abnormality had a prolonged QTc interval compared with a control group of 55 healthy non-diabetic subjects (mean±SD 401±2msec) (p<0.001) and diabetic patients with ³2 abnormalities of cardiac autonomic function had a longer QTc interval than those with no evidence of CAN. There was a direct linear relationship between the severity of CAN and the QTc interval (r=0.559, p<0. 001), and the frequency of prolonged (>434msec, normal mean+2SD) resting QTc interval increased with the increasing number of abnormalities (CAN score 0, 1, 2, ³3:0%, 8%, 54%, and 63%), respectively. 15 patients had a prolonged QTe interval (mean 447msec) and 40 patients had a normal QTc interval (mean 414msec). The two groups were comparable in age (56 vs. 58yrs), and duration of diabetes (9 vs. 8yrs) and not comparable in degree of glycemic control (HbA1c 11.6 vs. 14.3%). All of 15 patients with a prolonged QTc interval had evidence of CAN. However, 32% (15 of 47) of patients with CAN had a prolonged QTc interval. Conclusion: These results suggest that the resting QTc interval may be an additional, noninvasive diagnostic tool in the assessment of CAN in patients with diabetes mellitus.