학생정신건강검진 시범운영사업에 따른 추진방안

김현정,김윤영,이혜숙,현미나,남동현,김상원,안동현 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.1

Purpose: The purpose of the study was to·find the strategies of mental health screening in school. Based on the literature review, we discuss the importance of screening students in schools for mental health problems. Methods: Data from the 2008 Korean Mental Health Screening in Schools(2008-KMHSS) are used to estimate the outline of this screening. We administered the questionnaire for satisfaction of 2008-KMHSS for students(N=1,280), parents(N=2,672), school nurses(N=75), teachers(N=685), district personnels(N=6), and mental health center staffs(N=37). Also we interviewed a part of them by telephone and e-mail. And we reviewed the tools and methods for screening students for emotional/behavioral problems. Results: Mental health screening in schools is a very important, yet worrisome, agenda that is in its very early stages. From the 2008 Korean Mental Health Screening in Schools, 9,588 students(12.9%) needed more evaluation in the first stage. Of these, 6,910(72.1%) completed the second stage screening. In this sample, 1,975(28.6%) utilized the mental health services in school or community. 38.3% of students and 43.7% of their parents notified the2008-KMHSS. But only 12.1% of students and 10.9% of their parents dissatisfied with the screening. 9.9% of teachers and 22.7% of school nurses dissatisfied with the screening. Among them the school nurses were mostly dissatisfied, and they complained work burden from KMHSS. Mental health center staffs complained similar issues. The Children's Problem-behavior Screening Questionnaire(CPSQ) and Adolescents' Mental-health & Problem-behavior Screening Questionnaire(AMPQ) were compatible to screen students in schools for mental health problems in first stage. Conclusion: Mental health screening in schools needs careful planning and implementation. For successful mental health screening in schools, several elements need to be considered: careful planning, collaboration, staff training, and integrative mental health programs and services in community or schools.

백색 발광 ZnS 박막 전기장 발광 소자의 제작 및 특성

현동걸,손상호,박태성,이동헌,이상윤 경북대학교 산업기술연구소 1990 産業技術硏究誌 Vol.18 No.-

The basic investigation on ZnS:P_rF_3 thin film electroluminescent devices was done, the phosphor(ZnS:P_rF_3) and the insulator(SiN_X:H) of which were deposited by electron beam evaporation and rf-plasma CVD, respectively. The red(650㎚) and blue(490㎚) light emission peaks were observed in the Electroluminescent spectrum. At the dopant concentration of 0.5mol%, the brightness of 90.6cd/㎡ was obtained under sinusoidal excitation of 1kHz.

약물 유해반응 보고지침 -임상시험의 안전성에 관한 정보 관리지침 -

지동현,김훈교,배진우,손동렬,김인범,전용관,박혜연 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

3-Acetamidophenyl Acetate의 Fries Rearrangement 반응 연구

김동현, 만노즈 마니캄, 풀라레디 보꾸, 이상윤, 조정석, 정상헌 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

Fries rearrangement has been known as highly useful reaction for the synthesis of ortho-or para-hydroxyacylbenzene from phenyl ester in the presence of Lewis acid catalyst. Conventionally, aluminum chloride was used as catalyst. For obtaining N-(4-acetyl-3-hydroxyphenyl)acetamide, 3-acetamidophenyl acetate was subjected to Fries Rearrangement reaction using aluminum chloride. Although the desired N-( 4-acetyl-3-hydroxyphenyl)acetamide was obtained, yield was very low. In addition, regioisomer N-(2-acetyl-5-hydroxyphenyl)acetamide and unexpected N-(2-methyl-4-oxo-4H-chromen-7-yl) acet-amide were obtained. NMR study and conversion to known compollnds confirmed the substitlltion pattern of these phenylacetamides and the structure of chromen-4-ones. Under this Fries Rearrangement condition, formation of chromen-4-one was newly discovered.

6-(3,4-디클로로페닐)아미노-7-클로로-5,8-퀴놀린디온의 항진균작용 및 안전성 평가

윤여표,김동현,이병무,허문영,정해문,강혜영,최정아,김도희,유충규 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

6-(3.4-Dichlorophenyl)amino-7-chloro-5.8-quinolinedione (RCK50) was tested for antifungal activities in mice systemically infected with Candida albicans. The therapeutic potential of RCK50 was also assessed in comparison with ketoconazole. RCK50 had ED_50 0.22±0.01 ㎎/㎏. Ketoconazole as a positive control had ED_50 6.00±1.70 ㎎/㎏. Intraperitoneally administered RCK50 at the ED_50 for 7 days and 14 days reduced Candida albicans colony count in the kidneys and liver. And administered RCK50 at the ED_50 for 14 days improved survival rates. The genotoxicities of RCK50 had been evaluated. RCK50 was negative in Ames test with Salmonella typhimurium and chromosomal aberration test in CHL cells. RCK50 did not show any clastogenic effect in mouse peripheral blood and was negative in mouse micronucleus assay. These results indicate that RCK50 has no genotoxic potential under these experimental conditions. Acute oral toxicity studies of RCK50 were carried out in ICR mice of both sexes. RCK50 did not show acute oral toxicities and LD_50 values were over 2.850 ㎎/㎏ in ICR mice.

鎔接殘留應力이 應力比에 따라 疲勞龜裂傳播에 미치는 影響

表東根,李龍福,金鍾鉉,吳湞淵 弘益大學校 1989 弘大論叢 Vol.21 No.2

To examine the effects of the welding residual stress on Mode I fatigue crack propagation behavior, 3mm thickness SS41 steel plate was welded by an Auto-matic Submerged Arc Welding. Initial residual stress and relaxation residual stresses according to each stress ratio were measured. The fatigue crack propagation behavior from the region of compressive residual stress to region of tensile residual stress was analyzed. The results predicted by the Forman's equation using the superposition approach of the respective stress intensity factors for the initial residual stress and for the applied stress according to each stress ratio were compared with experimental data. The validity of the superposition approach was investigated. The conclusion are summerized as follows: 1. When the component is subjected to a constant amplitude cyclic tensile loading, the welding residual stress is reduced as stress ratio increase. 2. As the fatigue crack is propagation through the compressive residual stress field, it was found that the effects of welding compressive residual stress on fatigue crack growth in weldments, and the stress ratio decreases, become larger and delay the fatigue crack growth rate. 3. For negative values of the effective stress ratio, R? in the welding compressive residual stress field, the prediction of fatigue crack growth rate by the Forman's equation were found to be corresponded to experimental data for stress ratio R?0.3, as the effective stress ratio R? approached zero, when the stress ratio R>0.3 the prediction of the fatigue crack growth rate by Forman's equation were found to be impossible.

수직 냉각면이 있는 정방형내 성층유체의 열적거동에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

This study was investigated by experimentals on the thermal behavior of stratified fluids in the square cavity with the vertical cooling surface by variation of initial temperature and cooling surface temperature and concluded as follows: 1. When the cooling surface temperature of the square cavity was -4℃. the supercooling phenomena was occurred every times regardless initial temperature of fluids and when -6℃ freezing was begun with out supercooling phenomena. 2. The higher the initial temperature was, the longer supercooling phenomena duration was, and the longer the supercooling phnomena was, the higher the temperature of the upper fluids was. 3. When the supercooling phenomena of water was occurred, the rate of temperature decrease of silicon oil was higher and when there was no supercooling phenomena, it was almost same the rate of temperature decrease.

농촌지역의 주의력결핍-과잉행동장애와 학습장애의 역학적 연구

김자윤,안동현,신영전 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4

연구목적 : 농촌지역 초등학생의 주의력결핍-과잉행동장애와 학습장애, 정신지체의 유병률을 조사하고, 보다 효과적인 장애아동 발견방법을 구하기 위해 연구를 계획하였다. 방 법 : 경기도 일개 군내 5개 면의 6개 초등학교, 1,256명에서 전체 학생을 대상으로 교사가 설문지를 작성한후 이를 통해 1차 선별하는 전수(total population) 조사방법과 교사가 직접 1차 선별하는 핵심요원(Key informant) 조사방법을 이용해 문제아동을 선별하였고, 대상아동은 현장을 방문해 정신과적 면담이나 지능검사를 통해 확진하였다. 결 과 : 1) 유별률은 주의력결핍-과잉행동장애가 1.99%, 학습장애가 0.40%, 경도이상의 정신지체가 2.23%이었다. 2) 전수 조사와 핵심요원 조사를 비교하면, 전수 조사의 경우 경도 이상의 정신지체의 유병률이 유의하게 높은 것(전수 조사 3.29%, 핵심요원 조사 1.23%) 외에 핵심요원 조사와 유별률에서 유의한 차이는 없었다. 핵심요원 조사는 주의력결핍-과잉행동장애와 정신지체 등에 의한 학습부진의 양성 예측도가 전수 조사에서 사용된 파탄적 행동장애 평정 척도(Disruptive Behavior Disorders Rating Scale, DBDRS)나 학업 수행 평정 척도(Academic Performance Rating Scale, APRS)보다 높았다(DBDRS : 전수 조사 17.33%, 핵심요원 조사 41.67% ; APRS : 전수 조사 39.22%, 핵심요원 조사 44.44%). 진단 받은 아동만을 비교할 때 두 집단의 질병분포에서 유의한 차이는 없었다. 3) 부모와 교사가 다같이 아동의 문제를 인식하고 있을 때 실제 장애의 가능성이 높았다. 결 론 : 조사된 시점유병률은 주의력결핍-과잉행동장애가 1.99%, 학습장애, 정신지체가 각각 0.40%와 2.23%였다. 양성예측도와 진단별 일치도로 비교할 때 핵심요원을 이용한 조사가 장애아동 발견에 보다 효율적이었다. 장애아동 발견에 있어 교사 혹은 부모의 단일 경로의 정보는 신뢰도가 상대적으로 낮았고 두 경로를 합쳤을 때 신뢰도가 더욱 높아짐을 볼 수 있었다. 이 연구의 결과는 우리 나라 초등학생에서 주의력결핍-과잉행동장애와 정신지체의 유병률을 조사했다는 의의와 함께, 향후 학교 대상의 역할조사에서 핵심요원 조사방법의 유효성을 증명하는 것이다. Objectives : We atlempted to determine the prevalence rate of attention deficit-hyperactivity disorder, learning disorder, and mental retardation of elementary school children in a rural area, and to evaluate a cost, and time-efficient method for identifying of children with such disabilities. Methods : We studied 1,256 children from 6 elementary schools in a rural aiea using used two-stage design. At the first step, we used the key informant and the total population survey methods for identifying children with disability. Teacher checklists were used as screening instru-ments in total population survey. And at the second step, child interview and KEDI-WISC were employed to make diagnoses. Results : 1) The prevalence rate of attention-deficit/hyperactivity disorder(ADHD) was 1.99%. The prevalence rates of learning disorder(LD) and mental retardation(MR) were 0.40% and 2.23%, respectively. 2) The prevalence rate of MR was significantly higher in total population method compared with key informant method(3.29% vs. 1.23%). Other comparison of prevalence rates in two methods was not significantly different. Positive predictabilities of ADHD and learning disabilities by key informants were higher than by DBDRS and APRS, the checklists used in total population methods. 3) The probability of illness was much higher when the teacher and parents reported the problems of child concurrently. Conclusions : The prevalence rate of ADHD in elementary school children in the rural area was 1.99%. And the prevalence rates of LD and MR were 0.40% and 2.23%, respectively. Key informant method was more effective compared with total population survey in positive predictability and diagnostic concordance, In identifying children with disabilities, the combined data from teacher and a parent was most reliable.

뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

급성 심근 경색에서 시행한 관상 동맥 우회술의 조기 결과

지현근,이원용,김응중,두영철,한규록,오동진,임종윤 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8