Clear cell sarcoma of the kidney : Immunohistochemical study and flow cytometric DNA analysis of 7 cases

Choi, Yoon-Jung,Jung, Woo-Hee,Jung, Soon-Hee,Park, Chanil Yonsei University, College of Medicine 1994 Yonsei medical journal Vol.35 No.3

급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

침자가 성장기 및 성숙기 웅성 흰쥐의 혈액성분에 미치는 영향

윤범철,이성동,류정록,최태암 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Acupuncture, an over 2500 years old therapeutic method stemming from traditional oriental medicine, is nowadays wide open to modern medical science. With the widespread usage of acupuncture, the number of article about biomechanical or therapeutic effects of acupuncture from animal experiments and clinical trials is largely reported. In a previous study, we have reported that Joksamlee(ST36) acupuncture increases serum protein and glucose but decrease serum lipid and cholesterol. For further study, we was examined effects of Shenshu(B23) and Samumgyo(SP6) acupuncture stimulation on differential blood components in growing and adult male rate. 24 male Sprague-Dawley rats were randomly assigned into three groups; A1 (B23 and SP6 acupuncture in adult rats) group, A2 (B23 acupuncture in growing rats) group, and control group. The results obtained were as follows; 1. Body weight was significantly decreased in A1 and A2 groups. 2. Serum TP level was not changed, but albumin level was significantly increased in A2 group. 3. Serum glucose level was significantly increased in A1 group. 4. Serum TG level was significantly decreased in A2 group: PL level was significantly decreased in both A1 and A2 groups; FFA level was not changed. 5. Serum T.CHO, HDL-C and LDL-C levels were not changed in both A1 and A2. 6. Serum amylase activity was significantly increased in A1 group.

서울지역 복지회관의 결식아동의 영양적 건강상태

최윤정;박유신;장유경 한양대학교 2004 韓國 生活 科學 硏究 Vol.- No.24

This study was carried out to investigated the growth development and nutritional health of poorly-fed children in Seoul Welfare Center. All subjects underwent a structured interview for general characteristics, anthropometric measurement and nutritional status. The results are as follows : The subjects were 30(male : 14, female : 16), among 7 to 12 years old. In higher grade boy, physical growth and development were decreased. Among the subjects, 37.7% were skipped the breakfast. In food group frequencies, subjects had animal protein such as meats(82.1%), fish(58.6%), and vegetable protein such as legumes(73.3%) 2 times and less a week. The average intakes of energy, vitamin B2, calcium were below 75% of the recommended dietary allowance. More than half of the subjects were under-nutrition (deficient of RDA, below 75%) in energy, vitamin A, vitamin B2, niacin, calcium and iron. Consequently, for balanced growth and development, it is necessary for school or community based nutritional support to supply dairy products that are major source of vitamin B2 and calcium for poorly-fed children.

서울 및 경기지역 노인의 신체적 건강 및 기능적 건강 실태 조사

최윤정;박유신;이상선 한양대학교 2010 韓國 生活 科學 硏究 Vol.30 No.2

This study was performed to assess anthropometric status, functional health and physical fitness among the elderly in Seoul and Kyunggi-do. Four hundred forty free-living elderly people(127 male, 331 female), aged 65 or more were interviewed by trained interviewers using structured questionnaires including demographic information, activities of daily living(ADL), instrumental activities of daily living(IADL), physical activity. And they measured anthropometic status and physical fitness. All the data were analyzed by student t-test, chi-square analysis using SPSS 9.0 version at p<0.05. The results can be summarized as follow : Of all the subjects, 46.3% were obesity, especially 92.4% of female were abdominal obesity. In functional health status, ADL score was 6.62±1.54, and IADL score was 25.94±6.92. Most of the subjects were difficult to walk and run. Female was a significantly higher flexibility and body fat than male(p<0.001), whereas female was a significantly lower muscular endurance than male(p<0.001).

SJO¨GREN'S SYNDROME 환자에게 즉시 임프란트 술식을 행한 치험례

최정환,손동석,이지연,이윤서,안선희,이재목 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.5

The old edentulous patients experience xerostomia commonly. They have considerable difficulty in wearing tissue-supported prosthesis and high risk rate of caries. One of them is Sj□gren's syndrome patient. Sj□gren's syndrome is a chronic inflammatory autoimmune disorder that results in a lymphocyte-mediated destruction of exocrine glands. We planned to place implants immediately after extraction in this case of autoimmune disease. The advantages of immediate implant placement include considerable decrease in time from tooth extraction to placement of the final prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plan. We present a case of Sj□gren's syndrome patient treated with immediate implant placement & immediate loading in anterior region and immediate implant placement in posterior region.

자궁적출술 후 통증에 Gabapentin 의 진통효과

최종호,김창성,김은성,유건희,이윤기,문동언,윤건중 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.6

항암제(Adriamycin, Cyclophosphamide, 5-Fluorouracil)로 유발된 흰쥐의 간독성에 대한 Squalene의 효과

최영복,김종세,윤중식 조선대학교 기초과학연구소 1998 自然科學硏究 Vol.21 No.1

The objective of the present study was to investigate the cytotoxicity of Adriamycin〔ADM〕. Cyclophosphamide〔CP〕, 5-Fluorouracil〔5-FU〕 in mouse liver cells (group A, B, c), and the protective effect of squalene to the hepatocytes to which ADM, CP, and 5-Fu-induced cytotoxicity(group A-1, B-1, C-1) was examined by transmission electron microscope. In the group A, The cisternae of rough endolplasmic reticulum(RER) and smooth endoplasmic reticulum(SER) are dilated/disoriented at 24 hours and 48 hours. The inner and outer membrane of mitochondria are detached or destructed, and attached ribosomes of RER are diminished in number. The cisternae of the SER are dilated, and the cristae of mitochondria are disrupted at 72 hours and 96 hours. In the group A-1, the cisternae of the RER and the SER are dilated at 24 hours. The cisternae of the SER are dilated at 48 hours. The cell organelles of hepatocytes are recovered from cytotoxicity at 72 hours. At 96 hours, hepatocytes were simillar to those of normal hepatocytes. In the group B, the cisternae of RER were partially destructed and attached ribosomes were remarkable decreased at 24 hours. A number of the mitochondria were dilated and increased in number, the filamentous materials also detected at 72 hours. In the group B-1, the difference between the normal and the treated groups were not detected at 24 hours, but the few mitochondria were expanded at the 72 hours. In the group C, the nucleus was destroyed at 24 hours and 48 hours group, however, somewhat repaired at 72 hours group. The dilated inner cavity and the irregular lamellae of the RER were observed continually until 72 hours group. The inner cavity of the SER were dilated in all groups. However, the destroyed and the normal membrane were observed simultaneously at 72 hours group. The inner membrane of the mitochondria were almost repaired at 96 hours group. In the group C-1, the nucleus was a little finfluenced by the toxicity of 5-Fu at 24 hours and 48 hours, RER were observed to keep the typical lamella structure of cisternae from 24 to 72 hours group, but inner cavity kept on dilating. In SER, inner cavity were also observed to flatten from 24 to 72 hours group. Mitochondria were always shown normal. All cell organelles were similar to those of normal at 96 hours. Accordingly, it can be said that the treatment of SQ prevents the cytotoxicity of ADM, CP, 5-FU on cell organelles of liver cell and that is concerned with the formation of membrane system of cell organelles.

대학주변 원룸형 다가구주택에 있어서 거주자 평가에 의한 소음실태분석

최윤정 대한가정학회 2003 Human Ecology Research(HER) Vol.41 No.10

The purpose of this study is to make clear the present condition and the reason of noise in one-room type multi-family housing around the campus by residents' subjective responses. The respondents are 104 residents living in one-room type multi-family housing around the campus The results are as follows. 1) The residents show relatively non-positive responses at evening and night on the present condition of noise in outdoor and indoor of building or indoor of house unit. 2) The types of outdoor noise of building are checked frequently are 'talking loudness' and 'traffic noise'. 'Walking and talking sounds in stairs and corridors' among the types of indoor noise of building shows highest percentage. They answer 'living equipment noise' and 'water hammer' as major types of indoor noise of house unit.

안면부에 발생한 고정형 스포로트리쿰증 3례

최윤애,류영욱,정재봉,송준영,이규석 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

We experienced 3 cases of fixed type cutaneous sporotrichosis confined to the face. Case 1 was a 32-month old child, affected over the nose. Case 2 was a 25-year old man, affected over the left cheek. Case 3 was a 71-year old man, affected over the nose. Histopathologically, chronic granulomatous inflammation with pseudoepitheliomatous hyperplasia was observed. Mycologically, typical dark brown to black colored colonines with moist, wrinkled and membranous surfaces were cultured. All patients were completely cured by oral administration of saturated KI and itraconazole combined therapy in a short period(40-90 days).