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Park,Tae-Sun INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1971 YONSEI REPORTS ON TROPICAL MEDICINE Vol.2 No.1
Ladies and gentlemen! It is a great honor to inaugurate the Second Seminar on Tropical Medicine which is sponsored by the Institute of Tropical Medicine, Yonsei University. I sincerely welcome all the distinguished researchers and professors to Yonsei University Campus. Our 8,000 students, 2,000 faculty & staff members and 22,000 alumni also welcome you with me.
Ryu, Jin Sun,Choi, Sun Woo,Yun, Sung Su,Koo, Bon Hoon,Choi, In Seok,Kim, Seung Jun,Park, Joon Seong,Seok, Jeong-Ho,Yoon, Dong-Sup Yonsei University, College of Medicine 2018 Yonsei medical journal Vol.59 No.9
<P><B>Purpose</B></P><P>This study investigated the effectiveness of meaning-centered psychotherapy (MCP), which is known to be a helpful psychotherapeutic intervention in distressing conditions, for patients with pancreatobiliary cancer.</P><P><B>Materials and Methods</B></P><P>We recruited 37 patients with pancreatobiliary cancer from three university general hospitals and assessed their psychological characteristics. Patients who reported clinically significant emotional distress were recommended to undergo MCP. Patients who consented to MCP were provided four sessions of the therapy. Patient psychological characteristics were assessed again 2 months after MCP. For statistical comparison, outcome variables included anxiety, depression, mental adjustment to cancer, and quality of life (QoL), as well as the degree of stress and physical symptoms.</P><P><B>Results</B></P><P>Sixteen patients completed the MCP and the final assessment 2 months later. In the initial assessment, the patients receiving MCP showed higher levels of anxiety and depression than those not receiving MCP, and QoL was also lower in terms of role function, emotional function, social function, and global QoL. At the 2-month follow-up, the MCP group showed a significant improvement in anxiety (<I>p</I>=0.007), depression (<I>p</I>=0.010), and anxious preoccupation (<I>p</I><0.001). In addition, QoL significantly improved in the MCP group, while there was no significant change in the non-MCP group.</P><P><B>Conclusion</B></P><P>In this study, MCP showed potential therapeutic benefits against emotional distress in patients with pancreatobiliary cancer, improving their QoL.</P>
Anti-Toxoplasma Antibody Titers in Pregnant Women
Im,Kyung-il,Yong,Tai-Soon,Shin,Ho-Joon,Lee,Doo-Ho INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1991 YONSEI REPORTS ON TROPICAL MEDICINE Vol.22 No.1
톡소플라스마의 감염은 태아의 유산이나 선천성 기형을 일으킬 수 있으므로, 일반임신부에 대한 감염 상황의 조사는 톡소플라스마증이 임신 및 태아에 어떠한 영향을 미치는지에 대한 간접적인 자료를 얻을 수 있을 것이다. 이 연구에서는 산전 관리를 위하여 1990년 8월부터 1991년 2월까지 연세의료원에 내원한 일반임신부 중 618명의 혈청내 IgG 항체가를 간접형광항체법 및 효소면역검사법(ELIAS)으로 측정하고그 결과를 서로 비교하였으며, 아룰러 병력을 검토하였다. 간접형광항체법을 위한 항원의 제조는 마우스 복강내에서 계대 배양한 툭소프라스마 RH주의 tachyzoite를 슬라이드에 고정하여 사용하였으며, 효소면역검사법을 위하여는 tachyzoite를 균질화하여 인산완충용액에 추출한 항원을 사용하였다. 간접형광체법의 측정 결과는 총 618명 중 41명(6.6%)에서 양성반응(1:16 이상)을 보였으며, 이 중 1:16은 37명, 1:32는 3명, 1:64는 1명으로 나타났다. 효소면역검사법(ELISA)의 결과는 43명(7.0%)에서 양성 반응(흡광도 0.36 이상을 보였다. 간접형광항체법과 효소면역검사법에서 모두 양성의 항체가를 보인 경우는 618명중 12명(1.9%)이었으며, 간접형광항체법과 효소면역검사법으로는 음성인 경우가 29명이었고, 반대로 간접형광항체법에는 음성이었으나, 효소면역검사법으로는 양성의 항체가를 나타낸 경우가 31명으로, 개별적인 결과는 두 검사 간에 불일치하는 경우가 많았다. 한편, 양성 반응을 보인 일반임산주의 병력을 조사한 결과, 톡소플라스마 감염과 연관지을 근거는 부족하나, 태아사망 등으로 인한 유산, 소두증(microcephalus)으로 인한 신생아 사망, 양수과다증(hydroamnious)등의 경우를 찾아볼 수 있었다. Congenital infection of T. Gondii has been revealed to cause chorioretinitis, meningoencephalitis, hydrocephaly, microcephaly and mental retardation in man. So prenatal detection of antibodies against T. gondii in pregnant women is very important in managing these serious congenital abnormalities. In this study, a total of 618 sera were collected from pregnant women, who visited Severance Hospital, Yonsei University College of Medicine, for prenatal obstetric care from June 1990 to Deember 1990. Serum IgG antibody itiers were examined by IFA and ELIS, and the results obtained by these two test were compared. Forth-one (6.6%) out of 618 serum samples of pregnant women showed positive titers (higher than 1:16) detected by IFA. Of them. 37 cases showed 1:16.3 showed 1:32 and only 1 case was found to be 1:64. Forty-three (7.0%) among 618 tested sera were revealed to be positives (O.D. 0.36). Twelve cases (1.9%) showed positive reactions by both IFA and ELISA. Post obstetric history reviewed through their medical records of the positive cases of either IFA or ELISA showed several ovstetirc complications, such as abortion due to intrauterine fetal death, neonatal death, microcephalus and hydroamnios. Any of these complications could be attributed to toxoplasmosis during pregnancy.