분당 신도시 개발 이후 용인시의 공간구조 변화에 대한 연구

조지혜,김영욱,박영기 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

The purpose of this study was to analyze quantitatively the transformation of spatial structure in the near city of a newtown after the development of it The result is that the development of a newtown had an effect on the trans formation of spatial structure in the near city. The analysis shows that Yongin city's spatial configuration with near cities became strong. And its northwest was more integrated forward Bundang new city than old urban core of it. As a result, it shows a decline of the old urban core.

갑상선 종양에서 thrombin receptor (PAR-1)의 발현 양상

박지영,목지오,김여주,박형규,김철희,변동원,서교일,유명희,조현득,오미혜,김상진 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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일부 흡연 대학생의 지각된 스트레스와 흡연실태에 대한 상관관계 연구

강초록,권시내,권혜림,박수경,송인혜,오해인,이미지,한승아,황선아,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

In spite of the seriousness of smoking harm has been developed these days. the increase of national smoking rate and that the people in the twenties are especially leading the rise of national smoking rate is an important issue of national health. Smoking of the university students can occur health problem and cause loss of manpower and expenses in their social activity period. So then the actual state for prevention of smoking and development of a program to prohibit smoking has to be seized urgently and starting with the study of the realities of university students, the effort to find a related fluent of smoking has to be studied. Related to this, the purpose of this study is to seize the general characteristics of smoking university students and to find out the relationship between perceived stress and smoking status among smoking university students. In addition, by collating the relationship between perceived stress and smoking status among smoking university students we have the purpose to furnish the basal data of stress care, the best way to cope with stress through group training and the plan for nursing implementation to decrease the smoking rate. For this study, a survey was conducted for 204 smoking university students of 13 universities in Seoul from 9th of May to 16th of May, 2003. The collected data was analyzed by t-test, Pearson Correlation and ANOVA in the statistical packages SPSS/PC. Major findings of this study are as follows; 1. Of the 204 respondents 85.4% of them were male and 14.6% of them were female. The average age of the sample was 23.19 years old and 41.8% of them were in senior, 21.4% in junior, 16.9% in sophomore, 19.9% in freshman grade. The major motivation to start smoking was 'because of curiosity'(33.8%) and the first smoking experience was at 'senior high school' (41.9%) and at 'college' (41.9%). 2 The highest scored stress factor of smoking university students were stresses about school work. 3. 72.7% had experience to quit smoking at least one or more times. Most of the reason to keep on smoking was 'short will to quit'(51.0%) and the smoking place was usually at 'school' (41.4%). Most respondents for the number ofsmoking friends were '5 people and above' (73.2%). 4. There was a negative relationship between the general characteristics and the entire perceived stress, however, there was a positive relationship between the general characteristics and the perceived stress in 4 categories which is 'sex distinction', 'major of study', 'residence form' and' inmate'. 5. There was a negative relationship between the general characteristics and the entire smoking status, however, there was a positive relationship between the general characteristics and the smoking status in 2 categories which is 'presence of hobby' and 'number of smoking friends'. 6. There was a negative relationship between the perceived stress and the smoking status. Through this study we have seized the relationship between the general characteristics, perceived stress and the smoking status of smoking university students. There was a positive relationship between some of the general characteristics with the perceived stress and the smoking status of smoking university students. Also there was a negative relationship between the perceived stress and the smoking status.

서울 시내 4년제 남자 대학생의 우울과 흡연량, 흡연기간, 니코틴 의존도와의 관계

박지영,박소영,이미숙,백수진,신의경,예혜련,오승진,장윤정,조혜진,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

Background: With reports on the relation between smoking and depression appearing since 1980, it has become clear that depression is one of the psychodynamics of smoking, though there has been little or no progress made in the study of whether or not there is indeed a relation between depression and nicotine dependence. Purpose: The purpose of the study was to investigate the effects of depression on the amount and period of smoking and nicotine dependence among university man student smokers. Method: In periodical examination between 14 and 21, May, 2003, using 170 university male. The CES-D(Center for Epidemiologic Studies Depression) Scale and the FTQ(Fagerstrom Tolerance Qustionnaire) were utilized to measure the level of depression and nicotine dependency. The amount of smoking was calculated based on the number of cigarette used. Result: Results indicated that depression had something to do with amount of smoking. Nicotine dependence also was related to depression but total value was relatively low. finally the period of smoking had nothing to do with depression. Conclusion: The results of this study revealed that the amount of smoking of university man student smokers was very high. Both the amount of smoking and nicotine dependence were affected by levels of depression. Accordingly psychiatric nursing access such as emotional support is needed to manage depression and decrease smoking.

LLCE법에 의한 천연산 은어의 휘발성 향기성분 분석

김훈,조우진,안준석,조두희,김지혜,차용준 창원대학교 생활과학연구소 2003 생활과학연구 Vol.- No.7

The volatile compounds in natural sweet smelt were analyzed by liquid liquid continuous extraction/gas chromatography/mass spectrometry (LLCE/GC/MS) methods. A total of 64 compounds were detected in sample, and these were mainly composed of lipid oxidative compounds such as aldehydes, ketones, alcohols, acids and hydrocarbons besides terpens and aromatic compounds. Among these, 9-carbon compounds including (E)-2-nonenal, (E,Z)-2,6-nonadienal and (E,Z)-3,6-nonadien-1-ol were suspected to have a key role on odor of natural sweet smelt because these compounds have low odor threshold and water melon-like and melon-like odor, characteristic odor in sweet smelt.

비소세포 폐암종에서 Epidiermal growth factor receptor(EGFR)의 발현 양상

임석호,이지혜,조현득,오미혜,김의한 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

배경: 비소세포 폐암종에서 epidermal growth factor receptor (EGFR)의 발현이 예후에 미치는 영향에 대해서는 아직 일치된 결론에 이르지 못하고 있으며, 비소세포 폐암종의 조직 병리학적 소견으로는 종양의 진행 및 예후에 대해 예측이 불가능하다. 이에 저자들은 종양의 EGFR 발현과 임상 및 병리학적 특징과의 관계를 관찰하였다. 재료 및 방법: 1990년부터 2004년까지 순천향 대학교 천안병원에서 수술로 절제된 95명 환자의 포르말린에 고정한 파라핀 포매 조직을 이용하여 EGFR 항체를 이용한 면역조직화착 검사를 시행하였으며 이의 결과를 환자의 임상양상과 병리학적 소견과 비교 분석하였다. 결과: EGFR 발현과 환자의 생존기간을 비롯한 성별, TNM 임상병기, TU댕기, N-병기와는 관련이 없었으나 조직학적 유형중 편평상피암종은 47예중 43예가 양성 반응을 보여 통계학적으로 의미 있는 상관관계를 보였다(p=0.005). 그 외에 성별, 조직학적 유형, TNM 임상병기, T-병기, N-병기중 어떠한 변수도 생존기간과의 연관성을 보이지 않았다. 결론: 비소세포 폐암종에서 EGFR의 발현은 환자의 생존기간 및 임상병리학적 소견과 유의한 상관관계를 보이지 않으므로 예후인자로서의 이용은 현재로선 불가능하여 좀 더 많은 증례를 통한 연구가 필요할 것으로 사료된다. Background: The prognostic role of epidermal growth factor receptor (EGFR) remains controversial in patients with non-small cell lung cancer (NSCLC). Histopathologic findings cannot adequately predict disease progression, so we investigated the reladonship between EGFR and clinicopathologic feature. Methods: Using immunohistochemical techniques, we retrospecdvely analyzed formalin-fixed, paraffin-embedded samples from 95 padents with resected pathological NSCLCs. Then, we correlated these data with padents' clinical outcome and pathologic finding. Results: No reladonship was found between EGFR overexpression and patient survival when the entire cohort was considered. Multivariate factors including gender, histologic type, TNM stage, T stage and N stage were not correlated to poor outcome. Also, no factors revealed correlation with EGFR overexpression except histologic type. Squamous cell carcinoma showed positive reaction in 43 out of 47 patients(p=0.005). Condusion: This result indicated that EGFR overexpression in NSCLC showed no reladonship with patients' survival. Therefore, EGFR overexpression could not be used as a poor prognostic marker.

기립자세에서 발위치가 무릎 폄근의 등척성수축 근전도 활성도에 미치는 영향

김성중,권오윤,조상현,황지혜 한국전문물리치료학회 2001 한국전문물리치료학회지 Vol.8 No.2

This study was designed to identify the effects of foot position on electromyographic (EMG) activity of the quadriceps femoris during maximum voluntary contraction (MVC) in standing. Twenty young adults who had not experienced any knee injuries were recruited. Their Q-angles were within a normal range. They were asked to stand in five different foot positions (40˚externally rotated, 30˚ internally rotated, neutral, 20˚ plantarflexed, and 10˚dorsiflexed foot position). The EMG activities of the vastus lateralis (VL), rectum femoris (RF), and vastus medialis oblique (VMO) were recorded in standing by surface electrodes and normalized by MVC EMG values derived from manual muscle test. The normalized EMG activity levels (%MVC EMG) of muscles in the five foot positions were compared using repeated measures ANOVA. The EMG activity levels of the VL, RF, and VMO were the highest when foot was externally rotated. The EMG activity levels of the VL and RF were significantly different among the foot positions (p<.05). However, EMG activity levels of the VL, RF, VMO, and VMO/VL ratio did not show significant differences in each foot position (p> .05). The results suggest that the quadriceps femoris may be effectively activated by performing MVC a: an externally rotated foot position. Therefore, the externally rotated foot position can be considered as an effective foot position for quadriceps femoris strengthening exercise. Further studies are needed to identify whether there are differences in the effects of foot position on muscle strength after MVC exercise of quadriceps femoris in standing.

환기정도에 따른 수술실용 신발 종류가 수술실 오염에 미치는 영향 : How to Choose Suitable Shoes?

남경동,정혜선,박영신,원진희,주미자,성화신,이지혜,이병희,조경숙,배재춘 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two-hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony-counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

유방암의 위와 대장전이

유현아,김은영,서민지,정은,조민정,오현진,장지혜,박지찬,이정의,박석영 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2

Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.

일 대학병원에서 양극성장에 환자의 흡연 특성 : 정신분열병 환자와의 비교 연구

이강수,천덕희,김지혜,김현진,조현상 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

Objectives : This study aimed to investigate smoking characteristics and nicotine dependence severity in bipolar disorder Comparing those of schizophrenia. Methods : 70 bipolar and 123 schizophrenic patients, diagnosed using DSM-IV-TR criteria and treated at the Severance Mental Health Hospital, were interviewed regarding socio-demographic variables, smoking characteristics and Fagerstrom Test for Nicotine Dependence (FTND), designed to evaluate the intensity of smoking. Results : The rate of current smoking was 60.0% in the bipolar group, and 50.4% in the schizophrenia group. No significant difference was seen in terms of the rate of current smoking between the groups. Rates of having ever smoked also did not differ between bipolar (73%) and schizophrenic patients (65%). Daily cigarette consumption of bipolar patients (15.9 cigarettes/day) was significantly lower than that of schizophrenic patients (21.2 cigarettes/day), but FTND score didn't appear to differ between bipolar and schizophrenic patients. Bipolar females showed higher rate of current smoking (44%) than schizophrenic females (17%). Among bipolar patients, antipsychotics dose was not correlated with daily cigarette consumption and FTND total score. Age of disease onset didn't appear to differ between smokers and non-smokers in bipolar group. Conclusion : Although daily consumption was significantly lower in the bipolar group, the rate of smoking and smoking severity in bipolar disorder were as high as in schizophrenia. This fact suggests that the bipolar disorder might be related to the nicotinic acetylcholine system dysfunction as like schizophrenia.