老化過程에서 흰쥐 滑車神經의 軸索의 數 및 直徑의 變化

최영수,엄창섭,서영석 최신의학사 1987 最新醫學 Vol.30 No.8

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

Brushless DC 모터의 磁氣에너지 모델에 의한 토크 제어 시스템 구성

서기영,이수흠,문상필 경남대학교 공업기술연구소 2001 硏究論文集 Vol.19 No.-

본 논문은 자기에너지를 기본으로 한 브러시리스 DC모터의 토크 서보계를 현대 제어공학에 응용해서 새로운 모델을 구성하였다. 그리고 에너지 모델에서 토크와 회전자 자계에 저장된 에너지를 상태변수로 표현하였으며, 고속토크응답에는 무효전력의 주입이 불가능하다는 것을 알 수 있다. 브러시리스 DC모터의 제어에 의한 로봇 조정시스템으로 구성된 영역에서 부하 토크는 비 선형화가 상쇄되므로 정밀선형화 기법이 사용되어진다. 그리고 민감한 전력제어에서 발생하는 고속 토크응답은 시뮬레이션 결과에 의해서 나타내었다. 본 논문에서 제안한 제어시스템의 유용성은 시뮬레이션 결과에 의해서 그 타당성을 확인하였다. This paper present a new approach of the brushless DC motor control system based on magnetic energy model. In this model, the torque and the stored energies in rotor field are chosen as state variables, and these magnetic energies are decoupled. The field-oriented control of the brushless DC motor-robot manipulator system using exact linearizing method in order to cancel nonlinearity in load torque is constructed. It is shown from the simulation results that quick torque responses are obtained by reactive power control. The availabilities of a control system used in the proposed model are confirmed from simulation results.

강원지역의 자원관리를 위한 지리정보시스템 개발

서백수,임길재,정영준,송화선,류창희,민경원,서희정 강원대학교 석재복합신소재제품연구센터 1997 석재연 논문집 Vol.2 No.-

강원도는 오랫동안 금속, 비금속, 석재 및 석탄과 같은 지하자원들을 공급하는 국내 주요생산지로 알려져 왔으나, 장기적인 채광과 비 계획적인 생산으로 인하여 매장량이 고갈되고 있으며, 대외적으로 생산 경쟁력 마저 잃어가고 있다. 이러한 문제점에 대한 해결방안의 일환으로 본 연구에서는 강원도내에 산재되어 있는 지하자원의 분포, 자원 생산시설 및 생산량, 경제성, 자원개발, 환경문제 등 자원관리에 필요한 제반사항을 수행할 수 있는 강원지역 자원 종합관리 GIS 시스템을 개발하였다. 이 시스템의 개발은 방대한 양의 정보 조사 및 저장, 오랜 개발기간, 많은 소요인력 및 개발 비용이 요구되기 때문에 본 연구에서는 조기에 자원관리 GIS 시스템을 개발하여 이와 관련된 생산 및 연구 분야에 조기에 적용할 수 있도록, 일차년도에는 현재 석재복합 신소재제품 연구센터의 집중적 연구대상 지역인 태백지역에 대한 탄광지역을 중심으로 자원 종합관리 GIS 시스템을 개발하였다. The Kangwon province has been well-known to be one of major underground resource producing districts which are mainly supplying metals, non-metals, stones, and coals. However, due to the long-term mining and unplanned production, the natural resource reserves have been rapidly drained and oversea production competition has been losing. In this study, we has developed a GIS system for regional resource management in the Kangwon province, which can operate, maintain, and manage the distribution of underground resources, resource production facilities, production and economic development, and environmental issues. The development of this system requires the collection, analysis, evaluation, and storage for a huge amount of research data, and in addition, the long period of time, the big research man power, and big development cost. Accordingly, to shorten the development period of time and to early apply itself to production, this stage of study has been intensively developed a regional resource GIS system for managing the mines scattered in the Tabak province, which is one of hottest RRC's research areas.

한 , 미 , 일 3국 기업의 인터넷 활용단계 및 발전모델연구 : 시계열 분석을 중심으로

서영호,채영일,이현수 한국품질경영학회 2002 품질경영학회지 Vol.30 No.1

Recently, the range of using Internet in business is expanding rapidly. And through Internet, companies are strengthening both their internal efficiency and their external competitive advantage in the market. In recent years, building and managing companies' web sites are becoming unavoidable tasks in business. Such a trend is becoming more imperative in business over the world. There is a great deal of research in progress to study the cases of companies with increasing performance from the use of their Internet web sites. But it is considered that there has not been enough of study in the area of levels of Internet application in business especially in strategic areas and application levels among countries. This research is in the same line of the research that was carried out on such topics in 1999. study in 1999 showed that there are significant differences in the usage levels of Internet in business between countries with long history of using Internet and those who are not. The 1999 study also suggested the model on development stages of Internet usage in business. This study is the continuation of the 1999 research and used two years of data to compare and analyze the trend of the Internet development stages in leading corporations in Korea, U.S.A., and Japan. This study found that there have been significant developments in the ability to use Internet in business in three countries. The differences in Internet usage level in each stage among different countries are compared and analyzed in this study.

ASYMUNT: 21개 Noncentric 점군이 갖는 X선 데이터의 asymmetric Units

서일환,박정란,박영수,이진호,이창희,김문집 순천향대학교 기초과학연구소 1999 순천향자연과학연구 논문집 Vol.5 No.2

결정학적 가설 ??은 anomalous dispersion을 나타내는 원자를 갖고있는 비대칭 결정에 대해서는 성립하지 않는다. 만약 이들의 결정구조가 Lane group 보다는 오히려 noncentric point group의 X선 강도 데이터의 asymmetric unit로부터 정해질 수 있다면, 그 구조는 강도 데이터가 2배로 증가하기 때문에 보다 신뢰성이 증가한다. 본 논문에서는, 21개 noncentric point group 각각에 들어가는 강도 데이터의 asymmetric unit 의 정확한 범위를 계산하는 프로그램을 제안하였다.

성인간호학회지 논문(1989-2000)의 내용과 경향 분석

서문자,김소선,송미순,이명선,오의금,신경림,김옥수,이숙자,이영자,오효숙,정재심,김철규 성인간호학회 2001 성인간호학회지 Vol.13 No.4

"Journal of Korean Academy of Adult Nursing" has been published since 1989 and more than 330 articles have been published up 2000. We reviewed all the articles published in this journal to analyze the contents and trend of published articles and to find out the way of improvement both in quantity and quality of studies in this area. The results are as follows : 1) Ninety percent of articles were quantitative studies. Experimental design was used in 16.1% and quasi-experimental design was adapted in 73.6% of articles. Qualitative research were 10.3% of total articles reviewed. 2) Only 5.1% of articles described theoretical framework and 73.6% of experimentally designed articles included research hypotheses. 3) Among experimental studies, only one was true experimental studie design. Eighty nine point three persent had descriptive survey method among non-experimental studies. Amog the thirty four qualitative studies, phenomenologic(73.5%), grounded theory(14.7%), and ethnographic (11.8%) design were used. 4) Most of research subject were patients and few healthy people, healthcare worker, and patient family. 5) Psychosocial data collection method which used questionnaire were 53.7% and interview. physical measurement, observation were used in 22.8%. 8.2% 5.4% of articles respectively. 6) Total number of keywords were 692, and average number of key words per article was 2.2. Health-related keyword was the most frequently used according to four metaparadigm of nursing (human, health, nursing, and environment). Environment related keyword was rarely appeared. The number and quality of nursing research in "Journal of Korean Academy of Adult Nursing" have been improved continuously. It is difficult to find out special trend or characteristics which is unique in this journal because of relatively short history of adult nursing studies. This review study was performed to analyze adult nursing studies only in the view of quantitative aspect, but it is needed to analyse qualitatively to find philosophical or theoretical trend in nursing.

益植物의 生育에 미치는 土盆內의 Polyethylene film 遮斷效果에 關한 硏究

徐榮敎,愼英範,金龍洙 慶北大學校 새마을硏究所 1978 農村과 科學 Vol.1 No.-

Polyethylene film inserted between compost and pot-wall to reduce evaporative waterloss. Petunia planted in two Conditions of clay pot were watered at one to four days intervals to compare their effect on the growth of potted plant. Plant growth was reduced in the clay pot when watering interval and delayed, while forced in the polyethylene film inserted clay pot. All plant characters investigated in the polyethylene film inserted clay pot were more favorable than clay pot. Therefore, reduction of watering-cost can be expected by utilization of polyethylene film inserted clay pot likewise non-porous pot.

PID제어에 의한 單相 昇·降壓 整流器의 입력전류 특성에 관한 연구

徐基永,李壽欽,柳在葉,文相弼,李來一 경남대학교 신소재연구소 1999 論文集 Vol.11 No.-

Distortion Minimized of Input Current for Single-Phase Buck-Boost Rectifier is studied in the paper. To sinusoidal waveform the input current with a near-unity power factor over a wide variety of operating conditions, the output capacitor is operated with voltage reversibility for the supply by arranging the auxiliary diode and power switching device. Then the output voltage is superposed on the input voltage during on time duration of power switching devices in order to minimize the input current distortion caused by the small input voltage when changing the polarity. The tested setup, using two insulated-gate bipolar transistors(IGBT) and a microcomputer, is implemented and IGBT are switched with 20[kHz]. which is out of the audible band. Moreover a rigorous state-space analysis is introduced to predict the operation of the rectifier. The experimental and simulated results confirm that the input current can be sinusoidal waveform with a near-unity power factor and a satisfactory output voltage regulation can be achieved.