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Kwon,Ki-Tae,Lee,Woo-Sik,Kwon,Lee-Seung,Seong,Seung-Hwan,Kim,Young-Do,Kwon,Woo-Taeg 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-
It is possible not only to treat high concentration organic matter such as food wastes but also to utilize food wastes as resources according to the bio-energy generation such as methane. The method of co-digestion of mixed wastewater mixed with organic wastes such as sewage sludge concentrated waters together with drinking wastewater is the most ideal method. Radiation not only has germicidal power in water treatment, but also is effective in decomposing degradable organic matter. Second chemical contamination problem is also solved because it does not use chemicals. Introduction of radiation pretreatment system to solve problems caused by mixing of waste water and organic waste resources. Biological electrochemical fusion system is used to remove the nutrients contained in the organic matter-removed mixture. Through the development of a system for treatment of high concentration wastewater, the processing efficiency is verified through the universal water treatment system for wastewater containing high concentration organic matter in addition to treatment of wastewater.
면역 알고리즘을 이용한 AGV의 2자유도 PID 조향 제어기 설계에 관한 연구
이창훈,이진우,이영진,이권순 동아대학교 정보기술연구소 2002 情報技術硏究所論文誌 Vol.9 No.2
Immune system is an evolutionary biological system to protect innumerable foreign materials such as virus, germ cell, and et cetera. Immune algorithm is the modeling of this system's response that has adaptation and reliableness when disturbance occur. In this paper, Immune algorithm controller was proposed to control four wheels steering(4ws). Automated Guided vehicle(AGV) in container yard. And then the simulation result was analysed and compared with result of Neural Network PID controller.
조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성
김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3
Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.
( Myeong Jun Song ),( Jung Hyun Kwon ),( Soon Woo Nam ),( Tae Hee Lee ),( Young Woo Kang ),( Ji Woong Jang ),( Seok Hyun Kim ),( Byung Seok Lee5 ),( Sea Hwan Lee ),( Hong Soo Kim ),( Ji Hoon Kim ),( S 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: We aimed to evaluate the efficacy and safety of Daclatasvir (DAV) and Asunaprevir (ASV) in patients with chronic hepatitis C virus (HCV) and chronic renal failure (CRF). Methods: 22 chronic hemodialysis patients with HCV infection at 12 medical centers have prospectively enrolled from Feb, 2016 to Feb, 2017 (NCT02580474). Of those, 9 patients who were followed 12 weeks after treatment ended were included. We evaluated the virological responses at each week 4, 12, 24 and the 12-week sustained virologic response (SVR12). The tolerability and safety of patients were also evaluated. Results: Of these 20 patients, there had no resistance-associated variant of NS5A (NS5A RAVs) and 2 patients showed indeterminate NS5A RAVs. 12 patients (54.5%) completed the 24 weeks treatment of DAV and ASV. 6 patients (27.2%) have continued, but 4 patients discontinued study prior to 12 weeks. Overall, all patients (n=9) achieved SVR12. Virologic response at week 4, 12 and 24 showed 94.4% (17/18), 93.3% (14/15), and 100% (12/12) respectively. DCV and ASV were well tolerated among the majority of patients and discontinuation of the treatment due to adverse events (hypertension, bradycardia, leukemia) was occurred in 3 patients. In two patients with indeterminate NS5A RAVs, one achieved SVR12 but the other showed viral breakthrough and discontinued treatment. Conclusions: In this study, DAV and ASV combination therapy for chronic hemodialysis patients with HCV infection achieved high sustained virological response with few adverse events. Close monitoring of safety and tolerability may be necessary when treating chronic hepatitis C patients with CRF receiving DCV and ASV.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
葡萄(Campbell Early)의 結實에 미치는 GA 및 覆袋의 影響
權相洙,具禹書,朴正璂,權五昌,李容門 東亞大學校 1983 東亞論叢 Vol.20 No.3
葡萄 Campbell Early 의 無核果 生成 및 成熟促進을 위하여 GA₃ 濃度別 그리고 몇 가지 覆袋處理를 한 實驗結果는 다음과 같다. 1. 果房重과 果粒數는 滿開 8日前 處理가 適期로서 果房重은 無處理에 비해 76.4%, 果粒數는 80.6%였다. 2. 1果房當 無核粒率(92%)과 100粒中 種子數(12個)는 滿開 18日前, Gibberellin 處理+cellophane紙 覆袋區가 가장 良好하였다. 3. 果粒數와 種子數(r=0.826) 또한 種子數와 果重間에는 정의 相關關係(r=0.841)를 나타내었다. 4. 糖度는 無處理區보다 cellophane紙 覆袋區가 9.34% 로서 높았다. 含水量과 灰分은 無處理와 新聞紙 覆袋區가 높았고 cellophane 紙 覆袋區가 낮았다. 5. vitamin C 含量은 Gibberellin 處理時期가 빠르고 無核率이 높을수록 낮은 傾向이엇다. 處理間에 있어서는 無處理와 parchment紙 袋覆區 많았고 cellopnane紙 袋覆區가 含量이 적었다. 6. Gibberellin 處理時期를 앞당기고 cellophan紙 袋覆를 하면 無核率이 높은 反面 果粒數 果重이 減少되고, Gibberellin 處理時期를 늦추고 新聞紙 覆袋를 하면 果粒數 果重은 增加하지만 無核率이 낮아졌다. The results obtained by the Gibberellin and bagging treatment on the Campbellearly grape are as follows: 1. The suitable period of treatment for cluster weight and number of berry are to be before 8 days of full bloom. The cluster weight was 76.4% and number of berries were 80.6% compared with control. 2. The ratio seedless berries of 92% per cluster, and number of 12 seedss in 100 beries were showed the best on before 18 full bloom at the bagging plots of Gibberellin treatment+cellophane paper. 3. Number of berry and number of seed (r=0.826) also were showed mutual relation of plus between the number of seed and fruit weight. 4. Soluble solid was showed higher of 9.3% at the cellophane paper bagging plot and 9.34% at the parchment paper bagging plot than the control. Juice content and ash were showed high at the conthol and newspaper bagging plot, and low at the cellophane paper bagging plot. 5. The content of vitamin C was showed low tendency at the higher of the seedless ratio with the quick Gibberellin treatment period. At the betweentreatment, the control and parchment paper bagging plot were showed much, and showed less content at cellophane paper bagging plot. 6. In advance the period of Gibberellin treatment and had cellophane paper bagging then the ratio of seedless would be high, but on the contrary, the number of berry and fruit weight decreased, and had delay the period of Gibberellin treatment and had the newspaper bagging, the number of berry and fruit weight would be increased but the ratio of seedless was low.
정전 열 접합을 이용한 Multi-Substrate Bonding
이덕중,주병권,최우범,한정인,조경익,이광배,장진,오명환 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1
We performed silicon-to-glass bonding using silicon direct bonding followed by anodic bonding(SDAB). Initial bonding between glass and silicon was caused by the hydrophilic surfaces of silicon and glass ensemble using silicon direct bonding(SDB) method. We found that the bonded specimen using SDAB process had higher strength than one using anodic bonding process only. We performed multiple layer bonding by SDAB, which is glass- silicon -glass as sandwich structure. In the silicon wafer, the (1mm x 2mm x 500μm)-sized cavity was formed by the anisotropic etching of the silicon substrate in EPW(Ethylendiamin-Pyrocatechol-Water). And, the cavity was sealed with glass wafers by SDAB method.