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이윤근,권세환 중앙대학교 스포츠과학연구소 2000 體育硏究 Vol.- No.13

It is considered the most of sport drinks that the lack of a herb medicine. We tried to verify of a baseball plyer's the recover from fatigue through the taking an'u sung cho' which have great an effects in the internals. It was based on the fatigue survey report by subjective symptoms that an object to the high school baseball plyer(man:26 woman:24). 1. After taking that, it is showed to helpful the function of the respiratory organs, the muscular system, a joint, recover from fatigue. 2. It is good for mental state, nerve system that has nothing to do with ability to carry out directly, so it served keep a balance and comfortable mental state. 3. A period of 1 month, it is great an effects physically, mentally, nerve system add to other things about the recover from fatigue. 4. It should required to be in the spotlight as a sport drink thet 'u sung cho' follow-up the study of medically, nutritionally.

레미콘 회수수의 안정적 재활용을 위한 교반수조의 설비유형 효과

이문환,이세현,박영신,박재명 대한건축학회 2005 大韓建築學會論文集 : 構造系 Vol.21 No.2

Using the sludge water in producing ready mixed concrete, which is generated as washing surplus concrete after completing manufacturing and transportation of concrete is the best method in meeting the issue of cost of production and environment. However, in reality, using sludge water decreases Quality, and solid ingredients adhere to the transportation line of sludge water and the basin of sludge water, agitated to prevent precipitation of sludge, which incurs tremendous amount of repair expenses. In order to resolve the problems above, we have studied stable methods of supplying sludge water and experimentally reviewed the types of facilities. The result showed that a facility that added stabilizing agents which retarded hydration of unhydrated cement in sludge water for certain periods (2-3 days) and simultaneously agitated and moved by air diffusion and vertical flat blade impeller was most effective in stabilizing concentration of solid and preventing precipitation of solid in the bottom of basin. In addition, the performance of agitation and prevention of adherence of reaction basin of sludge water depended on selective efficiency of sand grain, and it has been studied that buffering inconsistent band of circulation of sludge water by operating the ring blower for air diffusion to the maximum was advantageous to preventing managing concentration and prevention of adherence.

그리드 연관성을 이용한 지능로봇용 환경 지도 형상의 신뢰성 향상에 관한 연구

임종환,이세진,강철웅 제주대학교 공과대학 첨단기술연구소 2005 尖端技術硏究所論文集 Vol.16 No.2

This paper addresses a new feature map building method that can minimizes the appearance of phantom features by using only sparse sonar data. The approach is composed of extraction of features and building a probability grid map using only the footprint of sparse sonar data, estimation of position uncertainty of the feature, and evaluation of the reliable features. A virtual circle association frame model has been developed, which associates two sonar footprints into a virtual circle frame. Using this model, geometric primitives such as line, point, or arc features are separately extracted. While extracting the feature, a grid map is also built using the orientation probability approach. Position uncertainty of each extracted feature is, then, estimated by considering both the position uncertainty of the robot and the measurement uncertainty of the sonar sensor. Finally, the reliable features among all extracted ones are evaluated from grid association method. The proposed methods have been tested in a real home environment with a mobile robot.

재생골재 생산방식의 차이에 따른 재생 굵은골재의 품질 특성에 관한 비교 연구

심종우,이문환,이세현,전현규 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

The purpose of this study is intended for effective recycling of waste concrete. It analyzes the quality 0 the recycled coarse aggregate with production types. The conclusions of the study are as follows. 1. The recycled coarse aggregate which is produced through 5th Crushing Process (A-Type) shows the improvement in grading and particle shape, reduction in an absorption rate until 1.14% due to removal of attached the mortar and paste. Therefore, it satisfies the standards of KS F 2573(recycled aggregate for concrete) as the first grade. 2. The recycled coarse aggregate which is produced through 3rd Crushing Process(B-Type) is suited to the quality prOVlSlOns of the standards of KS F 2573, shows a 3.12% absorption rate that is second grade as recycled coarse aggregate. Based on the above results, it is possible to product first and second grade recycled coarse aggregates with production types. It is concluded that recycled coarse aggregate with production types can be used as aggregate within required conditions. And more researches are also needed to make recycled coarse aggregate better to use for concrete.

안정화제 처리된 회수수를 사용한 콘크리트의 특성에 관한 실험적 연구

박영신,박재명,이세현,이문환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Recently, Most enterprises produced ready mixed concrete uses a mixing water as a recycling water without a density control in proportion to guide and standard. That is a cause of deterioration in the concrete quality like a reduce of strength, laitance, crack, etc. This study shows basic materials for development of ready mixed concrete recycling water density control system that holds down a deterioration in the concrete quality by using a mixed water treated recycling water with stabilizing agent and examines a possibility of re-using components of cement in recycling water. Therefore, in the experiment, we make a recycling water contains 3,5,7% of solid content ratio examines a property of a mixing water with a stabilizing agent and without it. Results of this study is next as follow. 1. The slump is decreased 1~2cm in a mixing without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 2. The air content is 4~4.7% in proportion to an increase of solid content without a stabilizing agent and the mixing with a stabilizing agent is similar to the standard mixing. 3. The compressive strength of an early curing age is tendency to increase both the mixing without a stabilizing agent and the mixing with a stabilizing agent. But, After 14days is passed, Compressive strength is decreased in a mixing without a stabilizing agent but increased a mixing with a stabilizing agent.

회수수 안정화제를 사용한 콘크리트의 공학적 특성에 관한 연구

김기정,金光華,이문환,이세현,한천구 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

In this study is investigated the engineering properties of concrete using stabilizing agent of recycling water in order to suggest a practical use of recycling water. According to the results. as stabilizing agent is added. fluidity and air content varies slightly with W/C, but does not make a big difference. Bleeding is reduced by adding stabilizing agent, and so it decreases by about 40% at the adding ratio of 0.15%. When stabilizing agent is not added, compressive strength decreases in comparison with plain concrete, but increases by adding stabilizing agent, so it is largest at adding ratio of 0.30%(W/C 30%) and 0.15%(W/C 40, 50%). Length change by drying shrinkage is larger than plain concrete in the case of no adding of stabilizing agent, but decreases by the use of stabilizing agent. Therefore, it is thought that when stabilizing agent is added to recycling water, quality deterioration of concrete is prevented, moreover, quality of concrete can be improved.

The Safety and Efficacy of Daclatasvir and Asunaprevir with Chronic HCV Genotype 1 Infection and Hemodialysis

( Myeong Jun Song ),( Jung Hyun Kwon ),( Soon Woo Nam ),( Tae Hee Lee ),( Young Woo Kang ),( Ji Woong Jang ),( Seok Hyun Kim ),( Byung Seok Lee5 ),( Sea Hwan Lee ),( Hong Soo Kim ),( Ji Hoon Kim ),( S 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: We aimed to evaluate the efficacy and safety of Daclatasvir (DAV) and Asunaprevir (ASV) in patients with chronic hepatitis C virus (HCV) and chronic renal failure (CRF). Methods: 22 chronic hemodialysis patients with HCV infection at 12 medical centers have prospectively enrolled from Feb, 2016 to Feb, 2017 (NCT02580474). Of those, 9 patients who were followed 12 weeks after treatment ended were included. We evaluated the virological responses at each week 4, 12, 24 and the 12-week sustained virologic response (SVR12). The tolerability and safety of patients were also evaluated. Results: Of these 20 patients, there had no resistance-associated variant of NS5A (NS5A RAVs) and 2 patients showed indeterminate NS5A RAVs. 12 patients (54.5%) completed the 24 weeks treatment of DAV and ASV. 6 patients (27.2%) have continued, but 4 patients discontinued study prior to 12 weeks. Overall, all patients (n=9) achieved SVR12. Virologic response at week 4, 12 and 24 showed 94.4% (17/18), 93.3% (14/15), and 100% (12/12) respectively. DCV and ASV were well tolerated among the majority of patients and discontinuation of the treatment due to adverse events (hypertension, bradycardia, leukemia) was occurred in 3 patients. In two patients with indeterminate NS5A RAVs, one achieved SVR12 but the other showed viral breakthrough and discontinued treatment. Conclusions: In this study, DAV and ASV combination therapy for chronic hemodialysis patients with HCV infection achieved high sustained virological response with few adverse events. Close monitoring of safety and tolerability may be necessary when treating chronic hepatitis C patients with CRF receiving DCV and ASV.

A Comparative Study of Daily 3-Gy Hypofractionated and 1.8-Gy Conventional Breast Irradiation in Early-Stage Breast Cancer

Lee, Sea-Won,Kim, Yeon-Joo,Shin, Kyung Hwan,Kim, Kyubo,Chie, Eui Kyu,Han, Wonshik,Im, Seock-Ah,Jung, So-Youn,Lee, Keun Seok,Lee, Eun Sook Wolters Kluwer Health 2016 Medicine Vol.95 No.19

<P><B>Abstract</B></P><P>We retrospectively compared accelerated hypofractionation (AHF) with conventional fractionation (CF) in the radiation therapy (RT) for early-stage breast cancer patients.</P><P>Three hundred seventy-nine early-stage (pT1–2 and pN0–1a) breast cancer patients who received RT with AHF after breast-conserving surgery (BCS) were included. These patients were matched with 379 corresponding patients who received BCS and RT with CF at a different center with respect to the year BCS was performed, patient age (±3 years), and cancer stage. The AHF regimen consisted of 39 Gy in 13 fractions to the whole breast and a consecutive boost of 9 to 12 Gy in 3 to 4 fractions to the tumor bed. CF comprised whole-breast irradiation up to 50.4 Gy in 28 fractions and a boost of 9 to 14 Gy in 5 to 7 fractions to the tumor bed.</P><P>The median follow-up period was 75 months (range, 3.8–110.8 months). There was no statistically significant difference between the AHF and CF groups in terms of age distribution, T and N stage, resection margin, and histologic grade. There were 5 ipsilateral breast tumor relapse (IBTR) cases in the AHF group compared with 7 cases in the CF group. Seven and eight locoregional relapse (LRR) cases were observed in the AHF and CF groups, respectively. The 7-year rates of IBTR-free survival, LRR-free survival, and disease-free survival were 98.9%, 98.4%, and 97.1% in the AHF group and 98.1%, 97.9%, and 96.0% in the CF group, respectively (<I>P</I> > 0.05). The incident rates of grade 3 edema, hyperpigmentation, or wet desquamation at the end of RT were higher in the CF group than in the AHF group (16.4% vs 0.2%, respectively; <I>P</I> < 0.01).</P><P>AHF RT of 39 Gy to the whole breast plus a 9-Gy boost in 16 fractions showed excellent tumor control and tolerable skin toxicity, a finding that is comparable to CF RT in patients with early-stage breast cancer.</P>

Retrospective analysis of intensity-modulated radiotherapy and three-dimensional conformal radiotherapy of postoperative treatment for biliary tract cancer

Lee, Hyo Chun,Lee, Jong Hoon,Lee, Sea-Won,Lee, Joo Hwan,Yu, Mina,Jang, Hong Seok,Kim, Sung Hwan The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.4

Purpose: This study was conducted to compare the outcome of three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) for the postoperative treatment of biliary tract cancer. Materials and Methods: From February 2008 to June 2016, 57 patients of biliary tract cancer treated with curative surgery followed by postoperative 3D-CRT (n = 27) or IMRT (n = 30) were retrospectively enrolled. Results: Median follow-up time was 23.6 months (range, 5.2 to 97.6 months) for all patients and 38.4 months (range, 27.0 to 89.2 months) for survivors. Two-year recurrence-free survival is higher in IMRT arm than 3D-CRT arm with a marginal significance (25.9% vs. 47.4%; p = 0.088). Locoregional recurrence-free survival (64.3% vs. 81.7%; p = 0.122) and distant metastasis-free survival (40.3% vs. 55.8%; p = 0.234) at two years did not show any statistical difference between two radiation modalities. In the multivariate analysis, extrahepatic cholangiocarcinoma, poorly-differentiated histologic grade, and higher stage were significant poor prognostic factors for survival. Severe treatment-related toxicity was not significantly different between two arms. Conclusions: IMRT showed comparable results with 3D-CRT in terms of recurrence, and survival, and radiotherapy toxicity for the postoperative treatment of biliary tract cancer.

Outcome of postoperative radiotherapy following radical prostatectomy: a single institutional experience

Lee, Sea-Won,Hwang, Tae-Kon,Hong, Sung-Hoo,Lee, Ji-Youl,Chung, Mi Joo,Jeong, Song Mi,Kim, Sung Hwan,Lee, Jong Hoon,Jang, Hong Seok,Yoon, Sei Chul The Korean Society for Radiation Oncology 2014 Radiation Oncology Journal Vol.32 No.3

Purpose: This single institutional study is aimed to observe the outcome of patients who received postoperative radiotherapy after radical prostatectomy. Materials and Methods: A total of 59 men with histologically identified prostate adenocarcinoma who had received postoperative radiation after radical prostatectomy from August 2005 to July 2011 in Seoul St. Mary's Hospital of the Catholic University of Korea, was included. They received 45-50 Gy to the pelvis and boost on the prostate bed was given up to total dose of 63-72 Gy (median, 64.8 Gy) in conventional fractionation. The proportion of patients given hormonal therapy and the pattern in which it was given were analyzed. Primary endpoint was biochemical relapse-free survival (bRFS) after radiotherapy completion. Secondary endpoint was overall survival (OS). Biochemical relapse was defined as a prostate-specific antigen level above 0.2 ng/mL. Results: After median follow-up of 53 months (range, 0 to 104 months), the 5-year bRFS of all patients was estimated 80.4%. The 5-year OS was estimated 96.6%. Patients who were given androgen deprivation therapy had a 5-year bRFS of 95.1% while the ones who were not given any had that of 40.0% (p < 0.01). However, the statistical significance in survival difference did not persist in multivariate analysis. The 3-year actuarial grade 3 chronic toxicity was 1.7% and no grade 3 acute toxicity was observed. Conclusion: The biochemical and toxicity outcome of post-radical prostatectomy radiotherapy in our institution is favorable and comparable to those of other studies.