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      • 구강균에 대한 각종 한약제의 증식 억제

        정영건,지원대,김성영,곽동주,서수교,백경연 한국위생과학회 1997 한국위생과학회지 Vol.3 No.1

        The effect of oriental medicines an the growth of oral bacteria(B. pumilus JU4, B. coagulans JU6, B. subtilis var globigii JU7 and B. subtilis var. globigii JU9) which were isolated from teeth, gums and tongues of patients was investigated. lt was shown that the water extracts of Glycyrrhiza glabra L. var. glandulifera Regel et Zucc., Schizandrae Fructus and Coptidis Rhizoma have the strong antimicrobial activity against every test organism. Especially, the water extract of Schizandrae Fructus has the most antimicrobial activity against all test bacteria of which MIC were the same as 0.25%. The growth of oral bacteria B. pumilus JU4 was inhibited by addition of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma in the concentration of 0.9%, 0.2% and 0.1% respectively. It was tested that specific growth rates of B. pumilus JU4 in each concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma. From the results, the test showed that mean of specific growth rates of B. pumilus JU4 decreased 102%, 186% and 210% in 3% concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma more than those in control respectively.

      • KCI등재

        용해실리카의 기준경도를 이용한 나노 압입시스템의 실험적 교정

        이윤희 ( Yun Hee Lee ),안승민 ( Seung Min Ahn ),김주영 ( Ju Young Kim ),박찬평 ( Chan Pyung Park ),장희광 ( Hee Kwang Jang ) 대한금속재료학회(구 대한금속학회) 2015 대한금속·재료학회지 Vol.53 No.3

        Indirect calibration of a nanoindentation system was performed by deriving a reference loading curve. This reference load-depth relationship was accomplished by assuming a perfect nanoindentation test on an ideal reference material; if all components in a nanoindentation system are well calibrated and the reference material has unique hardness and Young’s modulus, the indentation depth can be formulated with a function of the indentation load having two parts of contact and surrounding elastic depths. Substituting both the hardness and Young’s modulus of a fused silica into the derived function, the reference loading curve was plotted and directly compared with experimental data of the fused silica measured by two commercial nanoindenters. All indentation loading curves showed leftward shifts compared to the reference loading curve, and this is discussed, offering two reasons for the result, system compliance and indenter apex geometry.(Received January 6, 2014)

      • 조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

        주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

        Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

      • KCI등재

        대구지역 야생조류로부터 분리한 Salmonella속 균의 생물화학적 특성과 Plasmid Profile

        윤가리,이영주,김기석,탁연빈 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.2

        The present study was conducted to investigate the prevalence, biochemical properties and plasmid profiles of Salmonella organisms isolated from wild birds in Daegu area during the period from May, 1999 to August, 2000. Twenty strains of Salmonella were identified from 192 samples of heron feces and 86 samples of pigeon feces. Among Salmonella isolates, S. montevideo were the most frequent serotype (16 strains), 3 strains of them were S. typhimurium and the other one was untypable. The biochemical properties of 20 strains of Salmonella isolated were in accordance with the traditional characteristics of Salmonella spp. in the majority of biochemical test such as IMViC, carbohydrate fermentation and amino acid decarboxylation. The majority of isolates were highly susceptible to amikacin, ampicillin, amoxicillin, carbenicillin, cephalothin, ciprofloxacine, chloramphenicol, enrofloxacin, furazolidone, gentamicin, kanamycin, nalidixic acid, polymixin B and sulfamethoxazole, while they were moderately susceptible to streptomycin and tetracyclin. However, the majority of them were highly resistant to nitrofurantoin. In plasmid profile, 21.1 kilobase (Kb), 20 Kb and 13.2 Kb fractions were common to three S. tvphimurium and one untypable strains, and no fraction was shown in all strains of S. montevideo.

      • 케미컬오일을 이용한 ERF 연마 특성

        윤종호,이재종,이응숙,이동주,김영호 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

        Electro-rheological fluid is recently used for the micro polishing of 3-dimensional micro-aspherical lens. It's also used for polishing small area defects on the wide flat wafer. Since ER fluid shows a behavior of viscosity changing under certain electric fields, micro polishing efficiency may be enhanced for certain cases. In this paper, a perfluorinated carbonyl fluoride oil based ER fluids was used to improve surface polishing rate and submicron-scale accuracy. As the polishing electrodes, micro size cylindrical tools had been used for maximizing the electric field. An experimental device, which was applied for micro polishing a number of wafers of 4 inches in size and other workpieces, was made on a precision polishing system. It consisted of a steel electrode, a wafer fixture, 10mA current and DC 5kV power supply unit, and a controller unit. From the Experiments, the ER fluid is applicable for micro polishing of small parts.

      • NaCl 처리에 대한 벼 Callus 의 품종간 양이온함량 차이

        윤주,신서호,이영만 全南大學校 農業科學技術硏究所 1999 農業科學技術硏究 Vol.34 No.-

        Callus 현탁배양시 배양기간, NaCl 농도를 달리한 양이온 함량의 내염성 품종과 감수성 품종간 변화에서 callus 증식율은 NaCl 이 첨가된 배지에서 현탁배양 3주후 감수성 품종과 내염성 품종간 차이를 보이지 않지만, 6주, 9주 후에는 내염성 품종인 상해향혈나가 감수성 품종인 동진벼보다 NaCl 농도 증가에 따른 감소율이 훨씬 적게 나타났다. callus의 양이온 함량은 두 품종 모두에서 NaCl 농도가 증가함에 따라 ??, ??/??비율은 증가하나, ??, ??, ?? 이온은 감소하는 경향을 나타냈다. In vitro culture of rice(Oryza sativa L.), cation contents were different between the genotypes of tolerant and susceptible to NaCl treatment. Differences in callus proliferation between salt tolerant and susceptible genotypes due to NaCl content in culture media were not observed until 3 weeks of culture, but became clear 6 to 9 weeks after culture. That is, decrease in calluse growth due to increasing of NaCl content in the media was much lower in tolerant genotypes than in susceptible genotypes. Content of ?? and ??/?? ratio in callus increased, as NaCl concentration in medial increased, while that of ??, ?? and ?? decreased in tolerant as well as susceptible genotypes.

      • SCOPUSSCIEKCI등재

        정상교합과 부정교합에서의 상·하악골과 제 1 대구치 위치에 관한 비교연구

        윤병모,안병근,이건주,김선해,박영주,한호진 대한치과교정학회 1993 대한치과교정학회지 Vol.23 No.4

        There has been so much controversies about the position of upper and lower jaws, and their first permanent molars in normal occlusion and Angle's class ⅠㆍⅡㆍⅢ malocclusions. So, the purpose of this study is to compare the position of upper and lower jaws, and their first molars in normal occlusion and Angle's class ⅠㆍⅡㆍⅢ malocclusions by lateral cephalometric analysis. The sample consisted of one hundred and twenty girls(thirty in each group) who had completed growth. The findings of this study were as follows : 1. In class Ⅰ malocclusion, both maxilla and mandible were slightly posterior position than normal occlusion, but they showed harmonious relationship. 2. In class Ⅱ malocclusion, the mandible was greatly retruded, and the maxilla was also slightly retruded to the cranial base as compared with normal occlusion. 3. In class Ⅲ malocclusion, the maxilla was significantly retruded to the cranial base, but no significant difference was found in mandibular position as compared with normal occlusion. 4. The maxillary first molar was located at posterior position in class Ⅱ malocclusion, and anterior position in class Ⅲ malocclusion to the cranium, so that the rotation of mandible was influenced by that. 5. The mandibular first molar showed constant relationship to the mandible in all four group, but different position to the cranial base in direct proportion to the mandibular position. 6. On the treatment planning of class Ⅲ malocclusion, it seems to be better to promote the mandibular horizontal growth by ingibiting the verbical growth of masillary molar area, and on the treatment planning of class Ⅲ malocclusion, it seems to be better to promote the antero-inferior growth of maxilla and to promote the mandibular vertical growth by inducing the vertical growth of maxillary molar area.

      • 연령별 Antistreptolysin O 분포 및 정상치

        김선주,정명아,정현주,김윤정,맹국영 대한감염학회 1998 감염 Vol.30 No.4

        배 경 : ASO 검사는 S. pyogenes 감염과 류마티스열이나 급성 사구체신염 등 후유증을 진단하는데 매우 유용하다. ASO 정상치는 연령에 따라 달라지는 것으로 알려져 있으므로, 단회의 ASO 결과를 올바로 해석하기 위해서는 같은 지역의 동일한 연령의 정상치를 알고 있어야 한다. 방 법 : 저자들은 진주지역 학동기전 아동 (162명), 초등학생 (436명)과 성인 (231명) 세 군에서 ASO 정상치와 분포를 살펴보았다. 연쇄구균 감염 증상이나 징후가 없는 진주 지역 주민들을 대상으로 혈청내 ASO치를 자동화학분석기 (Cobas Mira, Roche)와 비탁기 (Behring Nephelometer 100 Analyzer)를 이용하여 정량 분석하였다. 결 과 : 학동기전 아동, 초등학생 및 성인에서의 평균 ASO치는 각각 71 IU/mL (표준편차 107), 285 IU/mL (표준편차 246) 및 80 IU/mL (표준편차 64) 이었고, 정상상한치는 각각 131 IU/mL, 433 IU/mL, 136 IU/mL 이었다. 결 론 : ASO 정상치 및 분포는 각 연령군에 따라 크게 다르므로, ASO 정상치는 연령에 따라 다르게 설정되어야 할 것이다. A군 연쇄구균 감염은 학동기전 아동이나 성인에서는 매우 드문 반면, 초등학생에서는 빈번함을 알 수 있었다. Background : Antistreptolysin O (ASO) is very useful as an indicator of recent streptococcal infection and its sequelae, such as rheumatic fever and acute glomerulonephritis. Becuase the upper limit of normal (ULN) value of ASO varies according to age, the ULN value of ASO in an area should be evaluated to accurately interpret single ASO levels of patients. Methods : The ULN value and distribution of ASO concentrations were investigated in three age groups of preschool children (N=162), elementary school children (N=436), and adults (N=231) in Chinju. ASO concentrations were measured quantitatively by autoanalyzer or nephelometer from sera of healthy population in Chinju who had no symptoms or signs of streptococcal infections. Results : The mean (±SD) ASO concentrations were 71 (±107) IU/mL, 285 (±246)IU/mL, and the UNL value of ASO concentratios were 131IU/mL, 433IU/mL, and 136 IU/mL in each group of preschool children, elementary school children, and adults, respectively. Conclusion : The distributio and ULN value of ASO concentrations varied according to age group. The ULN value of ASO concentrations should be set differently according to the patient's age. Group A streptococcal infections might be quite common in elementary school children, while very rare in preschool children or adults.

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