다수의 냉동시스템에 의한 저온 저장고의 에너지 성능평가

강동언,김성만,운종호,이의준,박영하,현명택 濟州大學校 産業技術硏究所 2000 산업기술연구소논문집 Vol.11 No.1

The cool storage system(CSS) is a specific building that is required only cooling load without heating during the whole year. CSS uses a electric energy which is very expensive and is required much amount of energy due to temperature differences between interior and ambient temperatures. The purpose of this study is to assess the energy performance of the multi-unit cooler operating control system. For the prediction of its performance, two types of test (KIER). First cell is equiped with one .are installed a t Korea Institute of Energy Research large unit cooler. and second cell consists of two small unit coolers. According to the results of experiments using these cells. the multi-unit cooler operating control system is found to be effective in energy saving and beneficial for storage due to much less deviation of temperature.

전기경련치료(ECT)시 뇌파의 비선형 분석 : 단일증례 연구 A Single Case Study

강웅구,이운철,정선주,윤세창,조맹제,이상훈,김용식 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 비선형 분석을 통해 전기경련 치료(ECT)의 적절성 및 효과를 판정할 수 있는 새로운 변인을 추출해 낼 가능성을 탐색하기 위하여 한 여성 우울증 환자에서 ECT중 기록한 뇌파의 단일증례 분석을 하였다. 방 법 : 1주일 간격을 둔 두 ECT 회기에서 치료전 안정상태, 마취후-경련전상태, 경련상태, 경련후 뇌파억제상태, 치료후 안정상태의 다섯 상태에 따른 뇌파를 디지털 기록한 데이터를 분석하였다. 결 과 : 분석의 결과 1) 뇌파가 10차원 이하 저차원의 결정론적 성질을 가지고있으며 2) 뇌파는 비정상적(non-stationary)이지만 비선형 지수들이 각 상태 뇌파를 안정적으로 구분해 줄 수 있고 3) ECT 회기의 진행에 따라 경련중 뇌파의 결정론적 성질이 증가하며 4) ECT 회기의 진행에 따라 치료전후 안정상태 뇌파의 최대발산지수(PLE) 및 상관차원이 증가한다는 사실을 관찰할 수 있었다. 결 론 : 단일증례에 대한 다양한 비선형 분석의 결과는 ECT의 치료효과를 정량화할 수 있는 변인으로서 PLE, 상관차원 등 비선형 변수들이 사용될 수 있을 가능성을 제시한다. Objectives : In order to search for new parameters for the evaluation of the adequacy of electroconvulsive therapy(ECT), the authors performed a non-linear analysis of electroencephalogram(EEG) recorded during the course of electroconvulsive therapy(ECT) in a single female patient with depression. Methods : Digitized EEG recordings from two ECT sessions spaced one week were analyzed at five different stages ; pretreatment stable, postanesthetic-preictal, ictal, postical suppression and posttreatment stable stages. Results : Our analysis showed that 1) EEG signals had low dimensional(below 10 dimensions) deterministic characteristics 2) although EEG was nonstationary signal, non-linear parameters could reliably differentiate between various stages we examined. 3) the deterministic property of ictal EEG increased according to the progression of sessions and 4) the primary Lyapunov exponent(PLE) and correlation dimension of pre- and post-treatment stable stage EEG increased according to the progression of sessions. Conclusion : In this single case study, results of various non-linear analyses suggested that non-linear variables extracted from EEG recordings during ECT may have utilities as tools for the quantitative evaluation of ECT.

Aspergillus sp. PS-104의 액침배양중 mycellial pellet 형성에 미치는 황토의 영향

강선철,구본성,태언희 한국환경농학회 2002 한국환경농학회지 Vol.21 No.1

유리인산 생산균을 생물비료화 하기 위한 노력의 일환으로 인산가용화능이 우수한 Aspergillus sp. PS-104 균주를 액침배양하면서 pellet 형성에 미치는 황토의 영향을 조사하였다. Aspergillussp. PS-104의 분생포자를 황토를 포함하는 PDB 배지에 접종하여50 rpm의 낮은 속도로 교반하여 배양하면 무정형의 불규칙적인pellet을 형성하는 반면에 150 rpm의 높은 속도로 배양하면 구형의 규칙적인 pellet을 형성하였다. 또한 0∼10% (W/V) 범위의황토 첨가시에는 황토의 농도가 높을수록 pellet의 크기가 작게 형성되었으며, 1.0% 황토 농도에서 1.0±0.1 mm의 가장 작은pellet이 형성되었다. 이 결과는 황토를 첨가하지 않는 경우에 비하여 약 4배 작아진 것이다. 그러나 황토 농도가 1.5% 이상 되면 무정형의 큰 pellet이 형성되었다. 또한 황토의 주성분인 SiO_2Fe_2O_3, A1_20_3, CaC0_3, Caso_4,MgC0_3 분말을 각각 O∼l.0% 농도로 배지에 첨가하여 pellet 형성에 미치는 영향을 조사한 결과Al_2O_3를 제외하고는 첨가물의 농도가 높을수록 작은 크기의pellet이 형성되었으며, MgCO_3를 첨가했을 때 가장 작은 크기의pellet을 형성하였다. In order to investigate effects of loess on the mycellial pellet formation a phosphate-solubilizing fungus Aspergillus sp. PS-104 was cultured in potato dextrose broth containing loess. The strain formed an amorphous pellet or loose aggregates agitated at a low speed (50 rpm) while spherical and regular pellets at a high speed (150 rpm). The higher concentration of loess was added, the smaller size of a pellet was formed during the submerged culture of the strain. As shown in results, being cultured in the PDB medium supplemented with 1.0% loess the pellet size was maximally reduced to a fourth compared to the control. Evaluating the addition effect of several components of loess such as SiO_2, Fe_2O_3, Al_2O_3, CaCO_3, CaSO_4 and MgCO_3 on the reduction of mycellial pellet size the higher concentration was supplied, the smaller size of pellet was formed except Al_2O_3 And the smallest pellet size was recorded at the concentration of 1.0% (W/V) magnesium carbonate.

다수의 냉동시스템에 의한 저온 저장고의 에너지 성능평가

김성만,윤종호,박영하,이의준,강동언,현명택 제주대학교 산업기술연구소 2000 尖端技術硏究所論文集 Vol.11 No.1

The cool storage system(CSS) is a specific building that is required only cooling load without heating during the whole year. CSS uses a electric energy which is very expensive and is required much amount of energy due to temperature differences between interior and ambient temperatures. The purpose of this study is to assess the energy performance of the multi-unit cooler operating control system. For the prediction of its performance, two types of test cell are installed at Korea Institute of Energy Research (KIER). First cell is equiped with one large unit cooler, and second cell consists of two small unit coolers. According to the results of experiments using these cells, the multi-unit cooler operating control system is found to be effective in energy saving and beneficial for storage due to much less deviation of temperature.

한국 재래 산양에서 Leptospira spp.에 대한 혈청역학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

Between January 1999 and September 2001, 948 sera (120 from each province except 108 from Chungbuk) from 8 provinces were sampled from Korean goats. All the samples were serologically tested for Leptospira spp. By the microscopic agglutination test against four L. interrogans serovars including canicola, icterohaemorrhagiae, pomona and hardjo, 948 Korean goats were confirmed as 11 seropositives (1.2%) only infected with L. icterohemorrhagiae. All positive sera were collected from Gyeonggi (5), Gangwon (4) and Chungbuk (2). Titration of them were classified as 1:100 of 10 sera except one case with 1:200 from Gyeonggi. It was meaningful that the pathogen in Korean goats was mainly distributed in the northen part of the country. Consequently, the results in the study were confirmed and analyzed the recent status of infection of leptospirosisas zoonotic agentsome in Korean goats.

혈액투석중인 만성신부전 환자에서 골대사 지표로써의 Osteocalcin치

송치운,이진홍,안미애,윤환중,윤상임,성기양,이강현,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Background : Serum osteocalcin is synthesized by osteoblast and has been shown to be sensitive indicator of bone turnover inpatients with various metabolic bone disease. In renal osteodystrophy, serum osteocalcin is elevated due to decreased renal clearance and elevated level of PTH. This study was done to evaluate the usefulness of serum osteocalcin as a marker of bone metabolism and the correlation with other biochemical markers of bone metabolism. Methods : We measured serum osteocalcin, calcium, phosphorus, ALP(alkaline phosphatase) and PTH(parathyroid hormone) in 37 patients with end stage renal disease on hemodialysis. Osteocalcin was determined by radioimmunoassay and PTH was determined by radioimmunometric assay. Results : 1) The mean level of serum osteocalcin in ESRD patients was 233.8± 218.2ng/ml which was significantly higher than that of controls(p<0.0001). 2) The mean level of serum PTH in ESRD patients was 40.5± 43.8pg/ml was significantly higher than that of controls(p<0.005). 3) There was a significant positive correlation between the level of serum PTH, ALP and the level of serum osteocalcin in ESRD patients. 4) By using multiple regression, PTH is most reliable factor that affect to elevated level of serum osteocalcin ( beta coefficient = 0.687, Sig T<0.05). Conclusion : Serum osteocalcin as a marker of bone metabolism in ESRD patients is more useful than other biochemical marker such as serum calcium, phosphorus, ALP and PTH is a most reliable factor that affect to elevated level of serum osteocalin.

당뇨병환자에서 게이트심장혈액풀신티그라피를 이용한 심기능 평가

윤상임,송치운,이진홍,안미애,성기양,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Major cardiovascular complications of diabetes are coronary atherosclerosis, diabetic dilated cardiomyopathy, autonomic neuropathy and those are major causes of morbidity and mortality in diabetic patients. Gated blood pool heart scan is noninvasive and useful method for evaluation of functional status of heart in diabetics. We evaluated 52 patients with diabetes and divided 3 groups. Group 1 were 11 patients without proteinuria or with proteinuria less than 550mng during 24 hours. Group 2 were 9 patients with proteinuria more than 550mg during 24 hours and group 3 were 32 patients with endstage renal diasese due to diabetes. We performed 99mTc-HSA cardiac gated blood pool scan and used left ventricular ejection fraction(LVEF), peak ejection rate(PEF) to indices of LV systolic function and peak filling rate(PER) to index of LV diastolic function. The results were follows : 1) LVEF, PER were significantly lower in diabetics with ESRD than diabetics without ESRD, but there were no significant difference between normal controls and diabetics without ESRD 2) PFR was significantly lower in diabetics than normal controls, but there were no significant differences in diabetics with or without nephropathy. 3) There were negative correlation between PER, PFR and duration of diabetes. On the basis of results, PFR is a LV functional index of GBPS which can disclose early change of LV dysfunction in patients with diabetes.

위암에서 장화생 발생 양상에 대한 연구

최은정,강상균,김창진 순천향대학교 1994 논문집 Vol.17 No.4

The pathogenic mechanisms of gastric carcinoma, which is the most common malignant tumor in Korea, have not been completely revealed, but several lines of evidence suggest that intestinal metaplasia contributes in some way to the gastric carcinogenesis. Histologically, the gastric carcinoma can be classified into two main types, the expanding type and the infiltrative type. Intestinal metaplasia can be classified into 3 types : type Ⅰ which is complete metaplasia, type Ⅱ and type Ⅲ which are incomplete metaplasia secreting sulphomucin. The expanding type has some correlations with incomplete sulphomucin secreting metaplasia. To investigate the relationship between patterns of intestinal metaplasia, especially sulphomucin producing metaplasia, and histologic types of gastric carcinoma, 80 cases of gastric carcinoma and 10 cases of gastric ulcer were studied histochemically with hematoxylin-eosin, periodic acid-Schiff alcian blue(PAS-AB : pH2.5) and high iron diamine alcian blue (HID-AB : pH2.5) stains. The results were as follows : 1. Of a total of 80 cases of gastric carcinoma, 21 cases(26%) were expanding type and 59 cases(74%) were infiltrative type. 2. Of 21 cases of expanding type, 6 cases(28%), 4 cases(19%) and 5 cases(25%) were type Ⅰ, type Ⅱ and type Ⅲ intestinal, which is higher rate than that of nonsulphomucin secreting type Ⅰ intestinal metaplasia. 3. Of 59 cases of infiltrative type, 18 cases(30%), 8 cases(14%) and 12 cases(20%) were type Ⅰ, type Ⅱ and type Ⅲ intestinal metaplasia respectively. Twenty cases(34%) were sulphomucin secreting type Ⅱ and typeⅢ metaplasia, which is slightly higher rate than that of nonsulphomucin secreting type Ⅰ metaplasia. 4. Non-metaplasia was found in 28% of expanding type, and in 36% of infiltrative type, which suggests that, compared to the expanding type, infiltrative type tends to be associated with non-metaplasia 5. Of 10 cases of gastric ulcer, 6 cases(60%), 2 cases(20%) and 1 case(10%) were type Ⅰ, type Ⅱ and type Ⅲ intestinal metaplasia respectively. Above results suggest that sulphomucin secreting type Ⅱ and Ⅲ intestinal metaplasia have some relationship with gastric carcinogenesis, and that infiltrative type is more frequently associated with non-metaplasia, while non-tumorous gastric lesion as peptic ulcer has frequently associated with type Ⅰ complete intestinal metaplasia. However, further studies on the profiles of mucins secreted by epithelial cells should be done to elucidate the relationships between intestinal metaplasia and gastric carcinogenesis.

한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구

한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3

The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.

三天地의 環境과 生物多樣性 : I. Enviornmental Factors and Flora I. 環境要因과 植物相에 關하여

신상천,이종운,배규호,전재인,강경화 嶺南大學校 基礎科學硏究所 1992 基礎科學硏究 Vol.12 No.-

Environmental factors and phytological aspects of Samchunimpoundment in Kyongsan, Kyongpook were studied. 40 quadrats in 4 sites had 94% herbaceous cover, 31% shrub cover and 18% tree cover. Ambrosia artemisiifolia var. elatior, Metaplexis japonica, Erigeron annuus, Humulus Japonicus, Eragrostis ferruginea, Artemisia princeps var. orientalis were dominant herbaceous species and found cultivated plants of Hordeumn vulgare var. hexastichon, Prunus persica, Morus alba and neophytes of Ambrosia artemisiifolia var. elatior, Erigeron canadensis, Erigeron annuus, Ailanthus altissima, Bidens bipinnata, Lactuca indica var. laciniata, Robinia pseudo-acacia, oenothera odorata, Euphobia maculata. The investigated sites were divided into 4 patterns based on the vegetation with high difference level and Ambrosia artemisiifolia var. elatior, Medicago sativa, Setaria viridis, Metaplexis japonica, Humulus japonicus, Calystegia japonica, Forsythia koreana, Lsctuca indica var. laciniata were different species group. More than 90% on the surface area of water mass covered with Nelumbo nucifera, Marsilea quadrifolia and Typha angustata and distributed Hydrilla verticillata, Ceratophyllum demersum, Trypa pseudo-incisa, Myriophyllum spicatum under water. Average data of environmental factor analysis are as followings; air temperature 25.8℃, ph 6.77, total hardness 117.94㎎/ℓ, SS 4.5㎎/ℓ,Do 3.3㎎/ℓ,BOD 6.6㎎/ℓ,COD 7.2㎎/ℓ,cl- 17.56㎎/ℓ,?? 7.14㎎/ℓ,Mn 0.05㎎/ℓ, Zn 0.04㎎/ℓ. Total quality of impoundment water were heavily polluted and were quality class Ⅳ.