근위 대퇴정을 이용한 대퇴 전자부 골절의 치료

문영완,서동현,강신택,권덕주,지용남,이기병 대한골절학회 2003 대한골절학회지 Vol.16 No.1

목 적 : 근위 대퇴정을 이용한 고령 환자의 대퇴전자간 골절의 치료결과에 대해 보고하고자 한다. 대상 및 방법 : 2001년 4월부터 2002년 2월까지 대전자부에서 소전자에 이르는 횡선골절 및 소전자 주위 분쇄골절로 압박고 나사 고정이 용이하지 않은 전자간 골절, 일반적인 전자간 골절에 대해 근위 대퇴정을 사용해 치료한 80례 중 추시가 가능했던 71례를 대상으로 하였으며, 추시과정 중 골유합 시기, 대퇴경간각, 지연나사의 활강, 수술시간 및 출혈량, 술중 및 술후 합병증 수술시 주의사항을 조사하였다. 결 과 : 평균연령은 77.5세, 평균추시기간은 9개월이었다. Evans의 분류법으로 골절을 분류하여 안정성, 불안정성 골절은 30례, 41례였다. 평균 골 유합 시비는 13.8주였고, 대퇴경간각은 수술직후 131.9 ± 5.21˚, 129.9 ± 6.04˚ 였으며 평균지연나사의 활강은 4.21±4.13㎜였다. 수술시간은 평균 61분, 출혈량은 평균 0.67pint(134cc)였다. 술중 합병증으로는 정복 실패 1례, 원위고정나사 삽입시 피질골 골절 1례, drill bit 파손 1례가 있었으며, 술후 합병증으로는 대퇴 경간각 소실(5도이상) 12례, 경부골절의 발생이 2례, 지연나사의 관절내 돌출 1례였다. 결 론 : 대퇴골 전자부 골절의 치료로 근위 대퇴정은 정확한 삽입 위치, 삽입시의 조심스러운 확공, 지연나사의 연골하 골에 단단하게 고정시키는 등의 주의를 한다면 수술시간, 출혈량 감소 등의 술중 합병증을 줄이고, 견고한 내고정을 통한 조기 보행을 가능하게 하며, 좋은 골유합 등이 기대되므로, 특히 고령, 분쇄골절, 역행성 골절, 골다공증이 심한 경우에서 바람직한 수술방법으로 사료된다. Purpose : To evaluate the treatment results of geriatric intertochanteric fractures using a proximal femoral nail. Materials and Methods : From April 2001 to February 2002, 71 cases of the intertrochanteric fractures involving lesser trochanter, transverse or reverse oblique intertrochanteric fracture. We evaluated the bone union time, neck-shaft angle, lag screw sliding by follow up radiographs, operation time, blood loss and complications. Results : The average age was 77.5 years old, the mean duration of follow-up was 9 months and the mean duration of bone union was 13.8 weeks. The average neck-shaft angle on immediate postop. x-ray was 131.9 ± 5.21˚ and 129.9 ± 6.04˚ at last follow up and the average lag screw sliding was 4.21 ± 4.13㎜. The average operation time was 61 minutes and blood loss was 0.67 pints(134cc). Intraoperative complications were inadequate reduction in one case, difficulty in distal transfixing in one case and drill bit failure in one case and postoperative complications were loss of neck-shaft angle(more than 5 degree) in 12 cases, femur neck fracture in 2 cases and intraarticular cutting out of femur neck screw in one case. Conclusions : The use of the proximal femoral nail could be appropriate for the fixation of communited or reverse oblique intertrochanteric fracture in elderly, osteroporotic patients for early ambulation, preventing shortening and rotation deformity, and reducing operation time and blood loss.

Helicobacter pylori 양성인 소화성 궤양 및 위염 환자에서 Helicobacter pylori 제균에 대한 판토프라졸 포함 삼제 요법의 임상효과 및 내약성에 대한 연구

서영호,이완식,주영은,김현수,최성규,유종선,김행재,서순팔,김세종 최신의학사 2000 最新醫學 Vol.43 No.11-12

식량정책면에서 본 양곡의 물가변동

문영인,서화원,윤여은 연세대학교 생활과학대학 1975 婦學 Vol.8 No.-

결핵치료제인 시판 리팜피신제제의 생체내 이용율

김종두,안기완,서영환,조경상,김철,김상도,홍순표 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

This study was attempted to investigate the dissolution rate and the bioavailability of commercially available rifampicin preparations after oral administration in nine normal volunteers. Cross-over design was used for the analysis. The dissolution test was conducted in artificial gastric juice and artificial intestinal juice using basket method with four rifampicin preparations (A, B, C, and D) which were pharmaceutically equivalent. The results were as follows; The dissolution rate was higher in the order of A>C>B>D in artificial gastric juice, and A>B>C>D in artificial intestinal juice. Area under the blood concentration time curve (AUC) was larger in order of A>C>B>D. Relative bioavailability(%) of rifampicin preparations were 93.6% for B, 97% for C, 84.4% for D preparation compared with standard A preparation. Peak blood concentration (Cmax) was higer in order of A>B>C>D. Peak time (Tmax) was larger in order of D>C>A>B. Absorption rate constant (Ka) was larger in order of B>A>D>C. there was little difference in elimination rate constant and biological half-life. The correlation of the dissolution rate in artificial gastric juice and area under the blood concentration time curve as well as correlation of the dissolution rate in artifical intestinal juice and peak time showed significant linear relationship. From the result of the this experiments, it can be concluded that for the choice of preparations, bioavailability must be performed in man because the bioavailability of rifampicin preparations showed big differences among commercial preparations which were abvertised as pharmaceutically equivalent, and that the bioavailability of rifampicin preparations in man partially could be predicted from the results of dissolution rate.

대장통과시간 측정용 방사선 비투과성 표지자인 KolomarkTM의 국내 개발

김지은,이풍렬,김영호,성인경,심상군,김재준,고광철,최규완,임효근,서수원 대한소화관운동학회 1999 Journal of Neurogastroenterology and Motility (JNM Vol.5 No.2

내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

The Clinical Utility of Microalbuminuria in Nephrotic Syndrome with Complete Remission, Isolated Microscopic Hematuria and Renal Transplantation Donors

Wan Suh Koo,Euy Jin Choi,Bong Yun Cha,Yoon Sik Chang,Young Suk Yoon,Ho Young Son,Byung Kee Bang,Kwan Su Hong,Suk Young Kim 대한내과학회 1988 The Korean Journal of Internal Medicine Vol.3 No.2

Changes of Plasma Angiotensin-Converting Enzyme Activity during Hemodialysis

Wan Suh Koo,Yong Joon Lee,Hye Su Kim,Suk Young Kim,Euy Jin Choi,Yoon Sik Chang,Young Suk Yoon,Byung Kee Bang 대한내과학회 1987 The Korean Journal of Internal Medicine Vol.2 No.1

사이버대학 콘텐츠품질관리센터에서 이루어지는 수업컨설팅에 관한 연구

서용완(Young-Wan Suh) 한국산학기술학회 2017 한국산학기술학회논문지 Vol.18 No.7

본 연구는 사이버대학 현장에서 이루어지고 있는 수업컨설팅의 사례를 분석하여 올바른 방향으로 원격대학에서 활성화 하여 질 높은 콘텐츠 개발에 도움이 되기 위해 진행하였다. 본 연구는 충남지역 A사이버대학의 콘텐츠품질관리센터에서 수행하고 있는 수업컨설팅 자료를 분석하고 본 센터에 근무하고 있는 연구원들과 인터뷰 자료를 토대로 현상학적 접근방법으로 탐색하였다. 연구를 통해 알 수 있었던 것은 수업컨설팅에 참여하는 교수들은 많은 부담을 가지고 있었으나, 강의 질 개선을 위해 비교적 적극적으로 참여하고 있었으며, 원격대학에서 이루어지는 생소한 환경에서의 교육법을 알고 싶어 했고 피드백을 제공받고 싶어 하였다. 또한 연구원들은 강의평가의 객관적인 틀을 가지고 여러 번 강의 촬영한 영상을 탐색하는 과정을 거쳐 교수자에게 피드백을 제공하지만, 전달과정에 있어서 어려움을 겪고 있었다. 보다 원활한 의사전달을 하기 위하여 교수자와 연구자 사이의 라포 형성이 되어져야 하며 강의 촬영 전 충분한 사전협의가 필요함을 알 수 있었다. 일반대학과 다르게 사이버대학은 학습자가 없는 강의실에서 카메라만 응시하며 수업컨설팅이 진행이 된다는 한계를 지니고 있다. 따라서 교수자들은 촬영 및 녹화에 대한 부담감은 가지고 있었다. 그러나, 사이버대학의 교수자들은 수업컨설팅에 보다 적극적으로 참여하여 질 높은 강의를 하고자 하는 의욕도 보였다. 본 연구에서 연구결과를 논의하고 사이버대학의 수업컨설팅의 확산과 효율적 방안을 제언하였다. This study analyzed cases of teaching consulting in the cyber university field and activated it in a remote university in the right direction to contribute to the development of high quality contents. This study analyzed the instructional consulting data of the Center for Content Quality Management at A Cyber University in Chungnam area and interviewed researchers working at the center using the phenomenological approach based on the data. This studyshowed that the professors participating in instructional consulting had manyproblems, but they were relatively active in improving the quality of the lectures. They wanted to know the teaching methods in the unfamiliar environment ofremote universities. In addition, the researchers had difficulty in delivering feedback to the instructor through the process of exploring images taken several times with the objective framework of lecture evaluation. To allowbetter communication, it was necessary to form rapport between the instructor and researcher. Unlike general universities, cyber universities have features and limitations in that they only take cameras in the classroom without learners and proceed with class consulting. Therefore, the teachers have a feeling of burden about shooting and recording, but they are less than general university teachers, and are more willing to engage in class consultationmore actively. In this study, the results of the research was discussed and the proposal of cyber universities" instruction consulting and the effective planis proposed.

Erythrocyte Sodium Transport in Dialyzed Uremic Patients

Koo, Wan Suh,Choi, Euy Jin,Yoon, Young-Suk,Chang, Yoon Sik,Kim, Suk Young,Bang, Byung Kee CATHOLIC MEDICAL CENTER 1988 Bulletin of the Clinical Research Institute Vol.16/17 No.1

To investigate the status of the Na^+ concentration and ionic fluxes in red cells of human subjects with dialyzed chronic uremia, the authors measured the Na^(+)_K^+ pump activity as well as Na^(+)-K^+ cotransport (CoT), Na^(+)-Li^+ countertransport (CTT) and Na^+ passive permeability in erythrocytes from 37 normal subjects and 23 chronic uremic patiens receiving maintenance hemodialysis. The mean intracellular Na^+ concentration [Na^+]i value in the pre-dialytic group was significantly lower than that in control subjects (p < .0001), but tended to recover to the normal value of [Na^+]i in the pest-dialytic group. The mean intracellular K^+ concentration value in the postdialytic group was significantly higher than that of the control group (p < .001), but not significantly different from that of the pre-dialytic group. It was found that the Na^(+)-K^+ pump activity of erythrocytes in the pre-and post-dialytic groups markedly decreased over that of the normal control group with statistical significance (p < .0001, respectively). The Na^(+)-K^+ pump activity in the post-dialytic group, however, tended to recover, but not significantly. The rate constant for ouabain-sensitive Na^+ efflux in the post-dialytic group was significantly decreased over that of the normal controls (p < .05). The authors observed a significant decrease of the Na^(+) CoT value (p < .001 respectively) and .ate constant for Na^(+) CoT (p < .05, respectively) in the patients with pre-and post-dialytic uremia vs. that of normal subjects. Also, the authors observed a marked decrease of the Na^(+)-Li^+ CTT value in the patients in the pre-and post-dialytic groups than that of the control subjects (p < .05, respectively). Passive Na^+ permeability in the patients with predialytic uremia was decreased markedly compared to the normal subjects (p < 10^-5), but its value in the post-dialytic group tended to recover to the normal value. In conclusion, our studies demonstrate that another possible mechanism of inhibition of the Na^(+)-K^+ pump in pre-dialytic uremia might then be a secondary adaptive response of the cell to maintain normal intracellular ion concentration and transmembrane ion gradients in the face of the reduced [Na^+]i due to decreased passive Na^+ permeability .