조산의 예측 지표로서의 fetal fibronectin의 유용성

정집광,이해혁,이정재,이석민,이순곤,남계현,이임순,이권해 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Objective: The purpose of this study was to evaluate clinical efficacy of fetal fibronectin as a marker to predictor of preterm labor. Materials & Methods: The study group consisted of sixty-eight healthy pregnant women, at gestational age between 24 and 36 weeks, who visited our department with vaginal discharge from April, 1995 to December, 1997. For comparison, we divided all of the pregnant women into two groups by the result of ROM-Check^®, positive groups(N=21) and negative groups(N=47). When preterm labor appeared, 50mg of ritodrine hydrochloride(Yutopar^®) mixed I liter of 5% dextrose solution was administered slowly intravenously. Results: 1) The gestational age at delivery and the interval time from admission to delivery in the positive groups were significantly shorter than those of the negative groups(p<0.05). 2) The positive groups had significantly lower birth weight and Apgar scores than the negative groups(p<0.05). 3) Among the negative groups, in case of tocolytics administration, the interval time from admission to delivery significantly delayed more than that time in case of no tocolytics administration(p<0.05). Conclusions: The detection of the fetal fibronectin in vaginal discharge had a useful method as a predictor of preterm labor. Tocolytics was more effective in the negative groups than in the positive groups.

폐경기 여성에서 호르몬 대치 요법시 병행 투여된 프로제스토젠 투여 방법에 따른 혈청 지질 및 지단백에 미치는 영향

이임순,전섭,이순곤,이해혁,이권해,정집광,이석민 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Objective : The purpose of our study is to evaluate the effect of different administration method of progestogen on lipid profiles including total cholesterol, LDL(low density lipoprotein)-cholesterol, HDL(high density lipoprotein)-cholesterol, triglycerides during hormone replacement therapy in postmenopausal women. Methods and Materials : Seventy-one postmenopausal women who were assigned to following groups (Group I : conjugated equine estrogen(CEE), 0.625 mg/day plus continuous medroxyprogesterone acetate (MPA), 2.5mg/day, Group II : CEE, 0.625 mg/day plus cyclic MPA, 5mg/day for 12days/month. And we measured serum total cholesterol, high density lipoprotein (HDL)-cholesterol, low density lipoprotein (LDL)-cholesterol, and triglycerides before hormone replacement therapy(HRT) and 12 months later after hormone replacement therapy. Results: 1. Total cholesterol decreased in group I,III. 2. HDL-cholesterol increased in group I,II,III. 3. LDL-cholesterol decrease in group I,II. 4. Triglycerides increased in group I,II,III. There was significance in serum total cholesterol and LDL-cholestrerol among three groups. Conclusions : Estrogen alone or in combination with progestogen both in cyclic and continuous use improves lipid profiles, so medroxyprogesterone acetate(MPA) does not seem to blunt estrogenic effect on lipid profiles.

대전시 노은 도매시장 채소류의 농약 잔류 실태 및 식이섭취량 추정

한국탁,이규승,이은경,이용재,고광용,원동준,이정원,권순덕 한국환경농학회 2003 한국환경농학회지 Vol.22 No.3

대전시 노은 도매시장에서 채취한 6종의 채소류 중 농약잔류량을 조사한 후 이에 대한 위해성 평가를 실시하였다. 전체 100건의 분석시료 중 농약이 검출된 시료의 비율은 46.0%이었고, 잔류허용기준 초과비율은 6.0% 이었다. 검출비율이 높은 시료는 상추(85.0%), 깻잎(80.0%), 오이(60.0%) 순이었고, 상추 3건, 깻잎 3건이 허용기준을 초과하였다. 살균제는 dicar-boximide계, 유기염소계, azole계 농약, 살충제는 유기인계, 합성 pyrethroid계 농약이 많이 검출되었다. 검출빈도가 높은 성분은 procymidone, chlorpyrifos, chlorothalonil, cypermethrin, EPN의 순이었다. 위해성을 평가하기 위해서 각 농작물에 대한 농약의 추정 섭취량과 ADI를 비교한 결과, 허용기준을 초과한 깻잎의 bitertanol, triflumizole, iprobenphos가 다른 성분에 비하여 높은 비율을 보였다. 그러나 각 농산물의 식이섭취량이 적어 ADI에 대한 추정섭취량의 비율이 0.46%이하로 나타나 그 영향이 매우 낮은 것으로 판단되었다. Pesticide residues in some vegetables collected at Noeun wholesale market in Daejeon were surveyed and assessed their risk In 100 samples, the detection rate of pesticide was 46.0% and the rate exceed MRL was 6.0%. Commodities showing high detection rate were lettuce(85.0%), perilla leaf(80.0%) and cucumber(60.0%). Dicarboximide, organochlorine, and azole fungicides and organophosphorus and pyrethroid insecticides were detected. Detection frequency of pesticide was in the order of procymidone, chlorpyrifos, chlerothalonil, cypermethrin and EPN. When the estimated intake amount of the pesticides were compared with ADI to assess their risk, bitertanol, triflumizole and iprobenphos in perilla leaf were higher rate than the other vegetables. However the total amounts of intake of pesticides were estimated to less than 0.46% of ADI.

Rocuronium의 애별투여방법이 모지내전근의 이완에 미치는 영향

최영균,김승수,이원진,조광래,이상은,김영환,임세훈,이정한,이근무,정순호,김영재,신치만 인제대학교 2009 仁濟醫學 Vol.30 No.-

Objective : There are controversies in pnmmg technique of rocuronium whether it can or can't shorten the onset time. We want to compare the effects of two different priming doses and intervals of rocuronium. Materials and Methods : After giving propofol, 50 patients were randomly assigned to 5 groups. Group I received a placebo, followed 3 min later by rocuronium 0.6 mg/kg. Priming doses and intervals of Group II, Ill, N, V were 0.06 rng/kg and 2 min, 0.12 mg/kg and 2 min, 0.06 rug/kg and 3 min, 0.12 mg/kg and 3 min, respectively. Total dose of rocuronium was 0.6mg/kg. Train of four (TOF) count or ratio and 1st twitch height of TOF (T1) were monitored with 15 secondsintervals. TOF ratio of each groups just before bolus injection, duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were compared. Results : Duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were decreased in priming groups compared to Group 1 (P < 0.01) In group V, significant depression of TOF ratio just before bolus injection was seen (P < 0.05). Conclusion : Priming technique with rocuronium is effective method to shorten the onset of neuromuscular block. But priming dose of rocuronium itself could cause hypoxia and aspiration in awake patients and should be used carefully. Priming dose of rocuronium 0.06 mg/kg and 2 minutes interval maybe relatively safe method.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

미기상규모 영역의 온실기체 승온효과에 관한 수치연구

이순환,서광수,김동희,황수진 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.3

The change of land use such as the construction of way in mountainous area and tunnel leads to the quantitative change of the greenhouse gas. This study tried to clarify the effect of the change of land use around Miryang Ice Valley on thermal environment of micro-meteorological scale by numerical experiment. We carried out several numerical experiment under different atmospheric conditions with different amount of greenhouse gases. Heating rate increased by the greenhouse gas in the ground level is average of 0.0073 K/day. And the increasing rate is smaller than the daily average heat crossing quantity.

고체 산화물 촉매의 퍼텐셜 에너지

李廣純 聖心女子大學校 1985 論文集 Vol.17 No.-

(110)-면에서 이루어진 산화알루미늄의 D-층에 대한 점 전하모형을 설정하고, 여든여섯개의 원자를 포함하고 있는 단위세포에 multipole expansion method을 적용시켰다. 점 전하의 크기를 화학양론적으로 할당하여 표면전하를 scale factor로 요구하였다. 이 방법으로 구한 단위세포의 정전기적 퍼텐셜 에너지는 Coulomb법칙과 일치하였다. 그리하여 multipple expansion 방법으로 퍼텐셩을 계산하는데 필수적인 direction cosine을 쉽게 계산할 수 있었다. 이를 확장하여 227개의 격자가 포함된 이차원과 삼차원 표면의 정전기적 퍼텐셜을 direct summation으로 구하였다. We have developed a point charge model of the D'-layer of the 110-surface of the γ-alumina surface, and extend the multipole expansion method for a unit cell which includes eight six atoms. The relative magnitude of talc assigned point-charges are determined from stoichiometry, and in this case, the surface is determined up to a scale factor. By direct comparison with the Coulomb's law, the requisite multipole expansion are found to always converge for l<16 for the unit cell of the 110-surface of the γ-alumina and its neighbours. It is, thus, quite feasible to store the necessary multipole moments in tabular form, and retrieve them for combination with the direction cosines to determine potential energies a associated with the particular unit cell within the lattice. We have extended the multipole expansion method to the 2D and 3D lattice plane of γ-alumina.

Fulminant Hepatits 治驗 2例

李承魯,陸淳劑,柳浩相,金吉洙,高侊道 中央醫學社 1976 中央醫學 Vol.31 No.5

Calculous anuria is one of the complications of upper urinary tract calculi and may be caused by mechanical obstruction at some point of the tract, renal insufficiency, and a combination of obstructive and renal factors. The clinical features may vary from a complete absence of symptom to the time when the patient observes he could not pass urine. An immediate roentgenogram and catheterization of the ureters in an attempt to restore the excretion of urine are always recommended and in from 50 to 55 per cent of the patients the calculus is expelled. Even if anuria recurs after withdrawal of the catheter, the patient is in better condition for surgical intervention as a result of the removal of accumulated nitrogenous waste products. Uric acid calculi comprise from 3.5 to 4 percent of urinary calculi. A low purine diet, allopurinol and alkalinization of urine are proved very effective in management of it. Recently we have experienced a case of calculous anuria due to bilateral ureteral stones in 41 years old man and present it with the review of the literatures.

Sezary증후군과 병발된 용혈성 빈혈 1예

유광하,진춘조,김홍승,이종인,심영학,정순희,이창훈 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

유구치 Stainless Steel Crown 주위의 치은염 치은열구 삼출액 및 치면세균막 부착도에 관한 연구

이광기,손동수 大韓小兒齒科學會 1985 大韓小兒齒科學會誌 Vol.12 No.1

The study was performed to evaluate the status of the marginal gingival tissue surrounding the Stainless Steel Crowned teeth comparing to the overall marginal gingival tissue of the same children use of plaque Index, Gingival Index and Gingival Crevichlar Fluid flow rate. The selected subjects for this study were 38 children (boys 18, girls 20) aged from 3 year - 5 month to 12 year - 3 month who have more than one Stainless Steel Crown in their mouth. The obtained results were as follows; 1. There was little deleterious effect on the marginal gingiva after delivery of Stainless Steel Crown. 2. In case of Satisfactory Stainless Steel Crown there was no deleterious effect on the marginal gingiva but in case of Unsatisfactory Stainless Steel Crown there was a little deleterious effect on the marginal gingiva. 3. In Plaque Index Stainless Steel Crowned teeth exhibited a little lower score than the natural teeth of control group but statistically there was no significant differences (p>0.05). 4. A strong positive correlation existed between the two of Gingival Index, Plaque Index and Gingival Crevicular Fluid flow rate. 5. 38.03% of examined Stainless Steel Crown was satisfactory and errors in crown crimp were the most common, with defects in crown length, position, contour, polish, contact and cementation following in order of decreasing frequency.