췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

광장공포증 유무에 따른 공황장애 환자의 공존병리와 증상 심각도의 비교 연구

임경희,장은진,김정범 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.2

연구목적 : 본 연구에서는 광장공포증을 동반하지 않은 공황장애 환자들(이하 비광장공포증군)과 광장공포증을 동반한 공황장애 환자들(이하 광장공포증군)의 공존병리와 증상의 심각도를 조사하여 두 질환의 본질을 규명하고 치료계획을 세우는데 도움을 얻고자 한다. 방 법 : 연구대상은 1998년 3월부터 2001년 7월까지 계명대학교 동산의료원 정신과에서 외래치료를 받아온 환자들로 비광장공포증군 26명, 광장공포증군 44명으로 구성된 총 70명이다. 평가도구는 9개의 증상차원을 평가하는 90문항으로 구성된 간이정신진단검사(SCL-90-R)와 공황장애의 필수적이고 전반적인 7가지 영역의 심각도를 평가하는 한국판 공황장애 심각도 척도를 사용하였다. 통계적 분석은 ANOVA, Chi-square test, student t-test, person correlaiton을 시행하였고, 통계적 유의수준은 p<.05로 하였다. 결 과 : 1) 광장공포증군의 광장공포증적 두려움과 회피의 정도는 경도에서 중등도 사이에 해당되는 것으로 나타났다(PDSS점수 : 1.46±0.94). 2) 인구통계학적 특성에 대해 광장공포증군과 비광장공포증군을 비교해 보면, 연령, 성별, 교육정도, 직업유무, 병력, 발병연령에서는 두 집단 간에 유의한 차이가 없었다(표 1). 3) 세 집단의 공존병리의 유형을 분석해 본 결과, 광장공포증군은 모든 증상차원에서 정상대조군 집단보다 유의하게 높은 점수를 얻었다. 비광장공포증군은 불안, 공포불안, 정신증 척도에서 정상대조군 집단 보다 유의하게 높은 점수를 얻었다(표2). 4) 광장공포증군은 비광장공포증군에 비해 신체화, 강박증, 적대감, 공포불안, 편집증척도에서 유의하게 높은 점수를 보였다(표 2). 5) 광장공포증군과 비광장공포증군의 심각도 비교에서는 내적감응적 두려움과 회피, 직무수행의 장해/고통, 사회적 기능의 장해/고통에서는 두 집단 간에 유의한 차이를 보이지 않았느아, 심각도 총점, 복합점수, 공황발작의 빈도, 공황발작 동안의 고통, 예기불안, 광장공포증적 두려움과 회피에서는 광장공포증군이 비광장공포증군에 비해 유의하게 높은 점수를 보였다(표 3). 6) 광장공포증군내에서 광장공포증적 두려움과 회피항목은 SCL-90-R의 정신증 척도를 제외한 신체화, 강박증, 대인민감성, 우울, 불안, 적대감, 공포불안, 편집증 척도와 유의한 정적상관관계를 보였다(표 4). 결 론 : 광장공포증군이 비광장공포증군에 비해 대부분의 필수증상의 심각도가 높을 뿐만 아니라 더 다양한 공존병리를 가지고 있음이 밝혀져 기본적으로 더 심한 질환임이 시사된다. 따라서 공황장애의 치료와 평가에 있어서 공존병리와 증상의 심각도를 함께 고려하고 공황장애에서 광장공포증이 동반되는 경우 이에 대한 더 적극적이고 집중적인 치료가 필요하겠다. Objectives : In this research comorbidity and severity of symptom of patients that have panic disorder without agoraphobia(PD) and with agoraphobia(PDA) were examined in order to study their nature more closely and also to help set up therapy plans. Method : 70 patients were diagnosed with PD(N=26) and PDA(N=44) by DSM-Ⅳ. SCL-90-R was administered to panic subjects and normal control subjects. PDSS were administered to panic subjects, the statistical analysis was conducted using ANOVA, Chi-square test, student t-test, Pearson Correlation analysis. statistical signifi-cance was p<.05. Results : 1) The degree of agoraphobic fear/avoidance of PDA indicated the level to from moderate(PDSS score 1.46 0.94). 2) There was no significant difference between the two groups(PD/PDA) in there sex, age, education level, occupation, duration of illness, onset of age. 3) After analyzing the comorbidity pattern of the three groups, PDA was significantly higher score than normal control group in all symptom level. PD had higher score than normal control groups in anxiety, phobic anxiety and psychotism. 4) PDA showed much a significantly higher score in Somaatization, Obsessive-Compulsive, Hostility, Phobic Anxiety, Paranoid Ideation when compared to PD. 5) There was no significant difference between the two groups(PD/PDA) in there interoceptive fear/avoidance, PDA had significantly higher scores than PD. 6) The agoraphobic fear/avoidance item within PDA had significant correlation with Somatization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression, Anxiety, Hostility, Phobic Anxiety, Paranoid Idation except significant correlation with psychoticism. Conclusion : As it is shown clearly in all the results, PDA had a higher level of severity than PD. It was also clarified that PDA had a variety of comorbidity. Therefore when evaluating the treatment of Panic Disorder, One has to consider the comorbidity and severity. A more positively and concentrated treatment will be needed when panic disorder is accompanied by agoraphobia.

대전대학교 학생의 음료섭취 실태 조사

임영희,박명순,정은영 대전대학교 생활과학연구소 1999 생활과학연구 Vol.5 No.-

The purpose of this study was to investigate beverage consumptions of students at Taejon University. This survey was carried out through questionnaires, and subjects were 265 students(110 males and 155 females) between June 9-24, 1999. All statistical data analysis were conducted using the SPSS/PC+. The results of this studies are follows. 1. Mean height of male and female students were 173.4㎝, 161.2㎝ and the mean body weight of those were 64.3㎏, 51.7㎏, respectively. 2. BMIs of male and female students were 21.4, 19.9, respectively. According to BMI underweight subjects were 24.2%, normal and overweight subjects were 67.2%, 8.7%, respectively. Also only 51.3% of the subjects correctly self judged their weight. 3. The preferred beverage were water(3.17), coke(3.06), coffee(2.94), milk (2.75) for male students, and water(3.02), milk(2.75), coke(2.63), coffee(2.63) for female students. 4. The criterion of choosing beverage was taste(58.1%), effects(13.2%), materials(12.1%), prices(10.9%). 5. Coffee was significant positive correlation between frequency of eating out and smoking, coke was frequency of snack and smoking.

UWB시스템용 초광대역 통과 필터 설계

임재현,김은정,김학선 한밭대학교 정보통신전문대학원 2004 정보통신전문대학원 논문집 Vol.2 No.1

본 논문에서는 UWB (Ultra-WidrBand)시스템에 사용되는 초광대역 통과 필터를 설계하였다. 고역 통과 필터와 저역 통과 필터를 직렬 연결하여 구현하였다. 10.6 GHz의 cut off주파수를 갖는 저역 통과 필터는 단락된 전송선로와 개방된 전송선로를 이용 하여 구현하였고, 3.1 GHz의 cut of주파수를 갖는 고역 통과 필터는 L과 C의 lumped소자를 이용하였다. 시뮬레이션 결과 통과 대역에서는 S11 값이 18 dB의 값을 얻었으며 두개의 cut off 주파수에서는 S21의 값이 10 dB 감쇄한 결과를 얻었다. In this paper, it was designed ultra-wide band pass filter for UWB(Ultra-Wide Band) system. There was inplemented series connection of high pass filter and low pass filter. Low pass filter accessed cut off frequency of 10.6GHz was designed using short-circuited stubs and open-circuited stubs. High pass filter assessed cut off frequency of 3.1GHz was designed using lumped elements of L and C. Simulation results were obtained 18 dB of S11 from pass band and attenuated 10dB of S21 from two cut off frequencies.

초등 과학 생명 영역 내용에 대한 학생들의 의문 유형과 해결방법에 관한 연구

임채성,최은아,박정인,이수진 부산교육대학교 과학교육연구소 2004 科學敎育硏究 Vol.29 No.-

In this study, the frequencies and types of questions about LIFE areas of the Science Curriculum of elementary school students were investigated through in-depth interviews with twelve 4th and 5th graders. The results of the research can be summarized as follows: (1) In conjectural question, the proportions of 'object exploration question' and 'object verification question' were high in all of the 4th graders and the students of low achievement level. (2) The numbers of causal questions generated by the 4th graders were much higher than those of the 5th graders. (3) The frequencies of the predictive, methodological, applicative questions were very low both in 4th and 5th grade students. (4) The numbers of conjectural questions were more in all students except the low achievement level of 4th graders at not-yet-taken contents than at already-taken ones. (5) The numbers of causal questions were more in all students except the low and middle achievement levels of 4th graders at not-yet-taken contents than at already-taken ones. (6) The numbers of the predictive, methodological, applicative questions of the 4th graders were more at not-yet-taken contents than at already-taken ones, whereas opposite trend in the 5th graders. (7) The numbers of students' curriculum-related questions were more in all students except the low and middle achievement levels of 4th graders at not-yet-taken contents than at already-taken ones. (8) As ways for solving or seeking answers about questions, the 4th graders suggested methods of consulting experts or teachers (23.9%), internet searching (21.6%), and books or science-related encyclopedia (20.3%), while the 5th graders suggested the internet searching (36.5%), consulting experts or teachers (24.8%), and books or science-related encyclopedia (17.7%). Based an these results, we suggest several ways for improving the question-posing abilities of the students and adequate use of students' questions in the process of science teaching learning.

코우크로스로의 방출물에 노출된 근로자에서 발생한 폐암 증례

임현술,최정근,권은혜,김헌 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.1

목 적 : 소세포성 폐암으로 진단받은 56세 남자에대하여 과거 21년간 코우크스로에서 근무한 작업력과 폐암과의 관련성을 파악하고자 하였다. 방 법 : 증례에 대한 의무기록가 흉부컴퓨터단층촬영 및 조직검사, 세포검사를 검토하였다. 증례의 작업 내역, 공것 작업환경 측정 결과를 파악하였고 작업환경 측정과 동료근로자에 대한 역학조사를 실시하였다. 작업환경측정은 산업안전보건연구원에서 모든 근로자를 대상으로 2회 반복 측정하였으며, 측정시간은 근로자의 작업시간 전체를 포함한 1일 8시간으로 하였다. 시료채취 및 분석방법은 미국 국립산업안전보건연구소의 공정시험법과 미국 노동부 산업 안전보건청의 공정시험법을 이용하였다. 측정결과의 정확도를 높이소 오차를 줄이기 위하여 측정 전후에 적적한 보정을 실시하고 현장 공시료를 포함하였다. 동료 근로자 40명에 대하여 역학조사를 실시하였고 COEs의 노출정도를 평가하기 위하여 PAHs의 대사산물인 1-OHP와 2-naphthol을 소변에서 분석하였다. 결 과 : P제철 부속의원에서 1996년부터 1999년까지 COEs에 대하여 측정한 결과는 0.01-0.39 ㎎/㎥ 범위로 후발성 콜타르피치물질에 대한 노동부의 노출기준인 0.2 ㎎/㎥르 적용할 때 초과하는 경우가 있었다. 1999년 산업안전보건연구원에서 작업환경을 직접 측정한 결과 전체 측정 건수 136건 중 45건 (33.1 %)이 노출기준을 초과하였다. 동료 근로자 40명에 대한 역학조사에서 특별한 COEs에 의한 건강장해를 발견하지 못하였다. K업체와 S업체의 근로자에 대하여 충북대학교 의과대학 예방의학교실에서 측정한 요중 1-OHP와 2-naphthol은 대조군인 대학생에 비하여 유의하게 높았다(P<0.01). 결 론 : 중례는 21년간 코우크스 제조공정에서 COEs에 노출되었으며, 현재 작업환경측정 결과로 판단할 때 노출기준을 초과하여 노출되는 경우도 있다고 추정되며, 흡연은 COEs가 폐암 발생을 가중시키는 요인으로 작용하였다고 추정된다. 그러므로 증례의 폐암은 코우크스 제조공정에서 노출된 COEs와 관련이 있다고 생각하여 직업성암으로 판단하였다. Objectives : We report a case of lung cancer (small cell carcinoma) occurring in a worker exposed to coke oven emissions. Methods : We examined the chest CT and pathologic findings of the patient. We reviewed previous environmental measurements for coke oven emissions at the workers place of employment. Also we measured the airborne concentrations for coke oven emissions and total polycuclic aromatic hydrocarbons in the work area. Finally, we analyzed the 1-hydroxypyrene and 2-naphthol concentrations in the subjects urine and compared this with student controls. Results : This case was a 56-year-old male who had worked in a coke oven plant within a steel manufacturing factory for 21 years (1977-1998). The airborne concentrations of coke oven emissions at the worksite were above the permissible exposure level (0.2 ㎎/㎥) in 45 cases (33.1%) among 136 workers. The concentrations of 1-hydroxypyrene and 2-naphthol in the subjects urine were statistically significantly elevated as compared with those of controls (P<0.01). Conclusions : We confirmed that the lung cancer occurring in this patient was as an occupational disease due to exposure to coke oven emissions. To prevent occupational cancer in coke oven plant workers, we must remodel the engineering procedure, begin comprehensive medical surveillance, educate workers on risks and the benefits of smoking cessation, and increase awareness of safety regulations in the workplace.

『말타의 유대인』과『볼포네』에 나타난 주인공의 기질연구

임은정 경기대학교 영어영문학회 2005 경기영문학 Vol.10 No.-

Christopher Marlowe is the father of English tragedy and the creator of English blank verse. Also the ardor of Marlowe's early Machiavellianism in The Jew of Malta. This play is first and foremost a play about a Jew whose overwhelming passion is for gold and the power that gold brings him. Barabas is a Jew who has gained and kept his wealth by Machiavellian devices and policies. The general terms of Machiavelli, even as interpreted by the Elizabethans, were capable of building a character on as grand a scale as Marlowe's other heroes. Barabas hates Christian, for he can see no goods in all their faith, but malice, falsehood, and excessive pride. The Jew of Malta is not a farce but tragedy. Ben Jonson is well-known as a playwright of the comical satires and powerfully influential in the younger wits who formed the Tribe of Ben in Elizabethan and Jacobean period. Jonson was a scholar and a classical antiquarian so he was on sound historical ground. Volpone is on the anti-acquisitive tradition inherited from the Middle Ages. In Volpone, we may find a philosophy of life that facilely divides the world into the knaves and their dupes, and identifying brains with roguery and innocence with folly. Volpone is an old magnifico of Venice who glories mere in the cunning purchase of his wealth than in the glad possessions. Volpone has no relative to whom to leave his fortune. This fact draws new clients with presents to his house daily. He is not motivated by greed in the beginning. He is much more of a gambler than a miser. But the development of mood is from an assured, self-satisfied cleverness at the beginning scene, through domination by the passions first of lust and then folly and then fear and then obsessive searching for amusement. Finally Volpone forfeits his complete identity, Iiterally lose himself when he has himself pronounced dead. Mosca is a parasite of Volpone as gadfly. In the beginning, he was a true parasite. He always satisfy his master's order for amusement and to assist master's plan. After that he is like a theatrical producer and becomes infatuated with his own cleverness. Self-possession ruins Mosca, as it does Volpone.

일부 성장기 학생 혈중 연농도의 성별 및 연령별 분포

임재언,강은용,최병선,서지영,홍연표,장임원,박정덕 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.2

대형경유차 저공해기술 적용에 따른 나노입자 배출특성

임철수,류정호,엄명도,황진우,김예은 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

Diesel engines which emit a lot of PM and NOx have been known as a main air polluter. Especially, diesel particulate matters (DPM) including black smoke are hazardous air pollutants to human health and environment. The nations retaining advanced engine technologies have reinforced emission regulations. To meet these regulations diesel engine manufacturers have developed low-emission diesel engines, aftertreatment equipments, alternative fuel technologies and so on. In this study, particle number concentrations characteristics according to particle size and engine driving conditions were analyzed when these low-emission technologies were applied. There was a tendency of increasing particle number concentrations from heavy-duty diesel engines with increasing engine rpm and load rate. In the cases of CDPF (Catalytic Diesel Particulate Filter), CNG (Compressed Natural Gas) engine and ULSD (Ultra Low Sulfur Diesel) more than 99% of particle number concentration were removed.