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      • Two new records of the genus Nola Leach, 1815 (Lepidoptera: Nolidae, Nolinae) from Laos

        Yeong–Bin Cha,Ulziijargal Bayarsaikhan,Sol–Moon Na,Dong–June Lee,Jae–Ho Ko,Tak–Gi Lee,Hyeong–Kyu Kim,Chang–Moon Jang,Han–Ul Kim,Yang–Seop Bae 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04

        The genus Nola (Nolidae, Nolinae) was established by Leach (1815), with the Noctua palliola Denis & Schiffermüller, 1775 (a junior subjective synonym of Phalaena cucullatella Linnaeus, 1758) from Vienna, Austria. Nola comprises over 200 species: Africa and western Palearctic approximately described 100 speices (Hacker et al., 2012); Oriental and Eastern Palearctic regions have over 100 species (László et al., 2010; Sasaki et al., 2011; Kononenko and Pinratana, 2013). Two species of the genus Nola Leach; Nola euryzonata (Hampson, 1900) and Nola lucidalis (Walker, 1865), reported for the first time in Laos. Illustrations of adults and genitalia of all the examined species are provided.

      • Ho-166 부착풍선도자를 이용한 방사선 조사의 돼지 관상동맥 스텐트 재협착 예방 효과

        김원 ( Kim Won ),정명호 ( Jeong Myeong Ho ),박옥영 ( Park Og Yeong ),정우곤 ( Jeong U Gon ),박우석 ( Park U Seog ),김주한 ( Kim Ju Han ),안영근 ( An Yeong Geun ),조정관 ( Jo Jeong Gwan ),박종춘 ( Park Jong Chun ),강정채 ( Kang Je 한국지질동맥경화학회 ( 구 한국지질학회 ) 2002 韓國脂質學會誌 Vol.12 No.1

        배경 : 국내에서 개발된 방사선 동위원소 Holmium-166 (166Ho)은 주로 베타선을 방출하며, 166Ho을 부착한 풍선도자를 이용하여 돼지 관상동맥 재협착 모형에서 풍선확장술 후 신생내막 증식을 전신적 부작용 없이 안전하고 효과적으로 억제하였음을 보고한 바 있다. 본 연구에서는 돼지 관상동맥 스텐트 재협착 모형에서 스텐트 시술 후 신생내막 증식에 의한 재협착 병변을 166Ho 부착 풍선도자를 이용하여 치료하여 그 효과를 관찰하고자 하였다. 방법

      • Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

        김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

        Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.

      • SCOPUSKCI등재

        대장암 주변에서 관찰되는 백색반점의 병리조직학적 특성과 임상적 의의

        김효종,조진만,장린,동석호,김윤화,장영운,박일랑,김병호,이정일 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

        Background/Aims: To investigate the difference between colorectal adenocarcinomas with white spots (foamy cells) and those without white spots, clinically and histopathologically, were examined 37 cases of colorectal adenocarcinomas were classified in this study. Methods: Two groups: those with white spots and those without. In each case, evidence of lymph node and liver metastasis was sought. Immunoreactive staining for macrophage was performed. Results: Increased incidence of exophytic tumors was found (73%, p=0.028) in the group with white spots. The incidences of lymph node metastasis were 33% vs. 45% between the group with white spots and the group of without, but the difference was not statistically significant. Conclusions: These results suggested that foamy cells might have a beneficial role in colorectal cancer, although they were not statistically significant. Therefore, further prospective study be warranted.

      • Protective Effects of Hyperoside against Carbon Tetrachloride-Induced Liver Damage in Mice

        Choi, Jun-Ho,Kim, Dong-Wook,Yun, Nari,Choi, Jae-Sue,Islam, Md. Nurul,Kim, Yeong-Shik,Lee, Sun-Mee American Chemical Society and American Society of 2011 Journal of natural products Vol.74 No.5

        <P>In this study, the hepatoprotective effects of hyperoside (<B>1</B>), a flavonoid glycoside isolated from <I>Artemisia capillaris</I>, have been examined against carbon tetrachloride (CCl<SUB>4</SUB>)-induced liver injury. Mice were treated intraperitoneally with vehicle or <B>1</B> (50, 100, and 200 mg·kg<SUP>−1</SUP>) 30 min before and 2 h after CCl<SUB>4</SUB> (20 μL·kg<SUP>−1</SUP>) injection. Levels of serum aminotransferases were increased 24 h after CCl<SUB>4</SUB> injection, and these increases were attenuated by <B>1</B>. Histological analysis showed that <B>1</B> prevented portal inflammation, centrizonal necrosis, and Kupffer cell hyperplasia. Lipid peroxidation was increased and hepatic glutathione content was decreased significantly after CCl<SUB>4</SUB> treatment, and these changes were reduced by administration of <B>1</B>. Protein and mRNA expression of tumor necrosis factor-α (TNF-α), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and heme oxygenase-1 (HO-1) and nuclear protein expression of nuclear factor erythroid 2-related factor 2 (Nrf2) significantly increased after CCl<SUB>4</SUB> injection. Compound <B>1</B> suppressed TNF-α, iNOS, and COX-2 protein and mRNA expression and augmented HO-1 protein and mRNA expression and Nrf2 nuclear protein expression. These results suggest that <B>1</B> has protective effects against CCl<SUB>4</SUB>-induced acute liver injury, and this protection is likely due to enhancement of the antioxidative defense system and suppression of the inflammatory response.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jnprdf/2011/jnprdf.2011.74.issue-5/np200001x/production/images/medium/np-2011-00001x_0006.gif'></P>

      • KCI등재후보

        8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

        강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

        Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

      • Antioxidant and Anti-Inflammatory Effects of Rhei Rhizoma and Coptidis Rhizoma Mixture on Reflux Esophagitis in Rats

        Kwon, O Jun,Kim, Min Yeong,Shin, Sung Ho,Lee, Ah Reum,Lee, Joo Young,Seo, Bu-il,Shin, Mi-Rae,Choi, Hyun Gyu,Kim, Jeong Ah,Min, Byung Sun,Kim, Gyo-Nam,Noh, Jeong Sook,Rhee, Man Hee,Roh, Seong-Soo Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-

        <P>The purpose of this study was to investigate the antioxidant and anti-inflammatory effects of the combined extract of Rhei rhizoma and Coptidis rhizoma (RC-mix) in experimental model of acute reflux esophagitis. The antioxidant activity was assessed by<I> in vitro</I> 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. RC-mix was given at 100, 200, and 400 mg/kg body weight 2 h prior to induction of reflux esophagitis (RE). After 5 h, the effects of RC-mix treated rats were compared with those of normal and control rats. The representative flavonoid contents of RC-mix, such as sennoside A, epiberberine, coptisine, palmatine, and berberine, were detected using HPLC. The elevated esophageal mucosa damage was markedly ameliorated by RC-mix treatment in a dose-dependent manner. Furthermore, the administration of RC-mix reduced the increase of serum reactive oxygen species (ROS) and peroxynitrite (ONOO<SUP>−</SUP>). The improvement of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) levels were marked in the group given RC-mix. Moreover, the elevation of inflammatory mediators and cytokines by nuclear factor-kappa B (NF-<I>κ</I>B) activation in control rats decreased by RC-mix pretreatment. These results indicate that RC-mix treatment reduces the pathological states of esophagitis<I> via</I> regulating NF-<I>κ</I>B mediated inflammation related to oxidative stress. </P>

      • KCI등재

        크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

        김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

        The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

      • Goethe의 “Faust” 작품에 나타난 죄의 의미

        金永鎬 慶尙大學校 1998 論文集 Vol.37 No.-

        Diese Abhandlung stellt sich die Aufgabe, das Wesen der Sunde in Goethes "Faust" zu analysieren. Nur in begrenzter Weise sieht Goethe den Menschen als Sunder an : Nur da, 재 er mit der niederen Seele begehrt oder die ihm gesetzte menschliche Schranke in seinem Streben uberschreitet. Nach christlich-reformatorischer Lehre ist der Mensch ein Sunder in der Totalitat seiner Existenz. Wenn er das Wesen der Sunde nach ihrer aktiven Seite hin beschreibt, kommt Goethe immer dem christlichen Verstandnis der Sunde nahe. Er entfernt sich vomChristentum, sobald es gilt, den umfang der Verstrickung des Menschen in die Sunde festzustellen. Hier entrichtet erdeutlich seinen Tribut an die idealistische Lehre von der Duplizitat der menschlichen Natur, die ihn mit der auf Platon zuruckgehenden Tradition verbindet. Neben dem Bosen laβt aller Idealismus das Gute im Menschen, sein Streben nach den Werten als von Gott anerkannte Leistung gelten. Goethe weicht deutlich auch durch sein tragisch-metaphysisches Verstandnis der Sunde vom Christentum ab. Die Sunde hat dem Menschen letztlich nicht das Bose gebracht, sondern das Gute. Damit der Mensch in dem Streben, durch das er sein Dasein steigert und fur die Verwandlung in eine hohere Existenzform rief wird, nicht gehemmt wird und erstarrt, ist die Sunde Werkzeug in der Hand des Herrn. Also gehort die Sunde als ein notwedkiges Glied in den Weltprozeβ hinein, in dem sich die Gottheit in der Steigerung der Welt und der Wesen offenbart und vervolkommnet. Also hat die Sunde nicht nur ihren Ursprung in Gott, sondern sie erhalt durch Gott auch Sinn und Gewicht. Damit ist die dunkle Ratselfrage, die auf der Sunde liegt und die Sophokles nicht loste, erhellt. Goethe hat im Unterschied von Sophokles die letztlich aufgelost, insofern die Tragik der Schuld nicht nur darin besteht, daβ Schuld dem Menschen von der Gottheit auferlegt ist sondern der Grund dafur sich der menschlichen Einsicht entzieht.

      • "국민윤리" 敎科內容의 模型設定에 關한 一硏究

        金渭錫,裵龍光,姜永晧,朴仁熙 慶北大學校 文理科大學 1977 文理學叢 Vol.4 No.-

        Based upon the point of view that man would be able to get self-perfection only in community and that, on the other hand, just the man is the origin of vitality of community, writers believe that value education program is needed an useful in the university curriculum. And they found that in substantial character the value education program means the instruction which is not only for a student to adapt himself to the system of the community, but also criticize the system of the community in order to realize the best social conditions. Then, it is important to establish the substantial object of "National Ethics" and to constitute the contents of curriculum of it, which is suitable to accomplish the object of "National Ethics." According to the view mentioned above in this paper, writers attempted to establish a model of contents of "National Ethies" as a university curriculum. Writers think that the substantial object of "National Ethics" must be established with reference to the most important problems for the nation to be solved. Writers believe, therefore, that such problems as ① Primitive Unification, ② Industrialization ③ National Welfare ④ Abundance upon which discoursed A.F.K Organski in his "This Stage of Political Development," or as ① State-Building ② Nation-Building ③ Participation ④ Distribution of which stated G. A. Almond and G. B. Powell in their "Comparative Politics: Developmental Approach," are the most important for us to solve: because the history of modernization of Western Europe would suggest an End-State model for the underdeveloped nations. The following conclusions were derived from the present study: First, a statue of a human being as the substantial object of "National Ethics" is one who eager to solve and accomplish such problems mentioned above. Second, according to the suggestions of the history of modernization of Western Europe, the contents of curriculum of "National Ethics", which would be able to accomplish the substantial object of the "National Ethics," must be constituted with the contents which cultivate the patriotism. And from the history of modernization of Western Europe writers find out the facts that such modern spirits as positivism, rationalism and so forth rested on the basis of their traditional thought. And so, Koreanic modern spirits must be derived from her traditional thought. Then writers conclude that the contents of "National Ethics" must be constituted with "Korean thought" and the thought of "Chyung-Hyo" which is one of the Korean traditional morals. Third, writers concluded that it is reasonable to exclude the chapter of "The Philosophy of Political Science" and "Criticism of Communism" from the contents of curriculum of "National Ethics," which is contained in present text of "National Ethics," and to treat each one as a independent subject if it is possible. Fourth, a system of "Korean Thought" which is stated in this paper is an example for further study.

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