계지의 항염 효과에 관한 연구

박히준,이지숙,이재동,김남재,표지희,강전모,최일환,김수영,심범상,이제헌,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : Cinnamomi Ramulus (CR), the young twing of Cinnamomi loureirii nees, has been used for treating symptoms related to pain. rheumatic arthritis and inflammation in Korean herb medicine. This study was carried out to investigate the anti-inflammatory effect of CR in vivo and in vitro. Methods : Extracts of CR were prepared and the chemical components of the extracts were examined by gas chromatography-mass spectrometry (GC-MS). The extracts were administrated to the rat paw edema model induced by carrageenan to evaluate the anti-inflammatory effect of CR. The expressions of nitric oxide (NO). prostaglandin E2(PGE2), inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 were also quantified in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages to survey the effect of CR in vitro. The main components were cinnamaldechyde and coumarin. Results : We examined the anti-inflammatory activity of the 80% ethanol extract of Cinnamomi Ramulus in vivo by using carrageenan-induced rat paw edema model. Maximum inhibition of 54.9% was noted at the dose of 1000㎎/㎏ after 2 hours of drug administration in carrageenan-induced rat paw edema and this showed a potent anti-inflammatory effect. Conclusions : The results showed that Cinnamomi Ramulus suppressed dose-dependently LPS-induced NO production in RAW 264.7 macrophages and also decreased iNOS protein expression. Cinnamomi Ramulus also showed a significant inhibitory effect in LPS-induced PGE2 production and COX-2 expression.

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

Jason S. Lee,김윤호,김익수,김보규,최희준,이지민,신희재,김정화,김지영,서상범,이호,Olivier Binda,Or Gozani,Gregg L. Semenza,김민형,김근일,황대희,백성희 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

Jason S. Lee,김윤호,김익수,김보규,최희준,이지민,신희재,김정화,김지영,서상범,이호,Olivier Binda,Or Gozani,Gregg L. Semenza,김민형,김근일,황대희,백성희 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

고카라트 Au-Zn-Pt 합금의 등온시효경화 거동

이희경,박영환,문희만,이정은,김형일 大韓齒科器材學會 2001 대한치과재료학회지 Vol.28 No.4

The isothermal age-hardening behavior of a high carat Au-Zn-Pt alloy was investigated by means of hardness test, X-ray diffraction study, microscopic observation and electron probe micro analysis. By the isothermal ageing of the solution-treated specimen at 300∼400℃, the hardness increased slowly at the initial stage of ageing and reached a maximum hardness values at 300∼400℃ was similar and suitable to use as the crown & bridge. By the isothermal ageing of the solution-treated specimen at 300∼400℃, three phases of the Au-rich α_1 phase with face-centered cubic structure,the Pt_3Zn a_2 phase with an ordered AuCu_(L1_2) type(f.c.c) and the Pt-rich a_3 phase with face-centered cubic structure were transformed into three phases of the α_1 phase, the α_3 phase and the PtZn β phase with an ordered AuCu I(L1_0) type. The hardening seemed to be attributed to the lattice strains of the matrix resulting from the transformation of the a_2 phase to the β phase. The overageing with softening was attributed to the coarsening of the nodule precipitates which seemed to be composed of the β phase and α_1 matrix.

身體 不自由 學生들의 體育授業에 對한 實態와 指導策에 關한 硏究

李商鍾,李惠姬,姜熙成 全北大學校 1980 論文集 Vol.22 No.-

The followings are the result of research on the actual condition of disabled students. To get the result, I met 122 middle school boys and 102 middle school girls and 103 high school boys and 52 high school girls. 1. They became the disabled man at the age of 4~6. They became the disabled man due to disease and accident. 2. Occupation of their protectors were mostly business and agriculture. 3. Most of the boys liked to play soccer and baseball and school girls liked volley ball. 4. They wanted to play pingpong because they thought pingpong was fit for their physical condition. 5. It was found that teachers of the physical education were not concerned about the disabled students. 6. They had study-hours for themselves and took a rest instead of outdoor sports because they didn't like to show their disabled bodies. 7. They felt unwell that they had been excluded at the school-hour of physical training and they wanted to take part in the study of physical education. 8. They were discontented with marks in physical examination and they wanted to have examination through another special ways. The guiding methods of disabled students in the instruction of physical education. 1. Physical educaters make them enjoy their pfavorite sports. 2. Physical educaters have to have much concern for them. 3. Physical educaters make them enjoy make kind of sports activity like another gerneral students because they wanted. 4. Their marks in physical education must be validly valued according to the special ways.

Transformer Bridge 방법을 이용한 자기변형 측정장치

이용호,신용돌,이영희,김희중,강일구 全北大學校 基礎科學硏究所 1991 基礎科學 Vol.14 No.1

간편하고 경제적인 transformer-ratio-arm bridge 회로를 자체 제작하여 몇 가지 잘 알려진 물질의 자기변형을 측정하였다. 전기용량 변환기에 진공 증착한 Al 전극판을 사용하여 와류효과를 줄였다. Bridge의 분해능은 10^-4pF정도였으며 7Å 정도의 길이변화의 분해능을 얻었다. Metaglass 2605SC,2605CO,2826MB에 대해 측정한 결과 공표치와 일치함을 보였다. An economical magnetostriciton measurement system is built. Using simple transformer-ratio-arm bridge we get the resolution of 7Å in length and 10^-4pF in capacitance. Vacuum coated thin film of Al is used as electrodes for the length-to-capacitance transducer which greatly reduces the eddy current cause varying magnetic field and improves sensitivity. The obtained results for well known Metglass 2605SC, 2605CO and 2826MB show good agreement with published data.

연속 역세척 모래여과기를 이용한 질소제거에 관한 연구

조희경,이병희 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

This study is to investigate biological denitrification removal efficiencies using continuous back-washing sand filter with high nitrate concentration influent. Three stages of studies with three different influent nitrate-nitrogen concentrations - 80, 120 and 160 ㎎/ℓ, were carried out. The electron donor for this study was methanol. Sand having a range of diameter from 2.0㎜ to 2.36㎜ was used as media. The nitrogen removal efficiencies were showed average values of 81%, 75% and 73% for each stage, respectively. The consumed amount of Methanol per Nitrogen expressed as M:N (Methanol : Nitrogen) was about 2.47 regardless of stage which is the theoretical value, although some variable results were shown. The effluent concentrations of suspended solids were increased proportional to influent nitrate concentrations. This result indicated that the size of reactor was not proper to handle suspended soilds from bioreaction. During this study, the influent pH had a range from 7.24 to 7.71, however, the pH in effluent was 8.33, 8.93 and 9.05 at each stage, repectively. This increase was believed due to the produced alkalinity from denitrification reaction.

Efficacy of Intracytoplasmic Sperm Injection for Leukocytospermia

강희규,--,--,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

White blood cells (WBCs) are present in most human ejaculates, but abnormally high concentration of seminal leukocytes map reflect an underlying pathological condition. The World Health Organization (WHO) has defined leukocytospermia as status of more than 10^(6) WBC/mL of semen. The purpose of this study was firstly, to compare the outcomes between conventional IVF and ICSl in leukocytospermia, and secondly, to investigate whether ICSI may be an alternation treatment for patients with leukocytospermia. Total 346 cycles of conventional IVF and ICSI candidates underwent IVF cycles at Eulji Hospital Infertility Clinic. Semen Parameters including concentration, motility, morphology of spermatozoa and concentration of leukocytes were assessed from the raw ejaculates. There was no difference in sperm concentration, motility and morphology. The rates of fertilization and good embryo development from ICSI were significantly higher than those from conventional IVF in leukocytospermia (60.4% & 32.5% respectively for ICSI group and 44.4% & 28.5%, respectively for IVF group, P<0.001). The pregnancy rate after ICSI was also higher than that from conventional IVF (34.0% vs 29.1%. P<0.05). These results indicate that the presence of seminal leukocyes (>1×10^(6) WBC/mL of semen) is adversely related with fertilization, embryo development and pregnancy rate. Therfore the measurement of seminal leukocytes in routine semen analysis appears to be of prognostic value with regard to male fertilizing potential. In conclusion. it is suggested that ICSI is an alternative choice of treatment for patients with leukocytospermia.

CAPD환자에서 복강내 도관 말단부의 위치에 따른 도관전위율 및 도관유지율의 비교

정용희,이태원,김희진,임천규,김명재 대한신장학회 2001 대한신장학회잡지 Vol.20 No.3

금연침에 대한 반응군과 비반응군의 유전자 다형성 차이 연구

윤동학,박히준,김승태,진수희,이수진,이혜정,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objectives : This study was designed to investigate the differences of effects in smoking cessation after acupuncture treatment and we hypothesized that the discrepancies might be caused by individual genetic differences. Methods : Acupuncture treatment was given to the subjects three times a week for the 231 healthy male Korean smokers without personal or familial history of psychiatric or neurological illness. We evaluated for differentiate responder and non-responder who showed more than 50% decrease in the cigarette consumption or the desire for smoking were regarded as responder, and less than 25% decrease in the cigarette consumption or the desire for smoking were regarded as non-responder, respectively. Allele and genotype frequencies of the Taq1 A polymorphism of dopamine D2 receptor (DRD2) gene were compared in 231male smokers. Chai-square analyses were performed to test for an interactive effect between the DRD2 Taq1 A allele. Results : The allele frequencies and genotype distributions of DRD2 gene among the smokers (n = 231) showed significant the differences in their genotype distributions. The responder and non-responder showed the difference in genotype distribution with a prevalence of A1 allele. A slightly positive association of DRD2 Taq1 A1 genotypes with smoking was observed. Conclusions : This experiment results indicate that the present of DRD2 allele genotype showing significant difference in the genotype distributions between responders and non-responders could be explained by the difference in the genetic effect of DRD2 A1 allele.