QT연장 증후군 환자에서 Head-Up Tilt Test에 의해 유발된 Torsades De Pointes 1례

전익수,차태준,김길수,김동완,김규종,김찬욱,김성만,주승재,이재우 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

필지단위 토지이용 정보체계 구축의 시안적 접근

김타열,강성길,장찬호 영남대학교 공업기술연구소 1999 工業技術硏究所論文集 Vol.27 No.2

Cities are confronted with the Information Age. Large cities, like Tae-gu, have different land use patterns that are characterized by highly demised land use pattern, vertical land use differentiation and mixed land use. We need more accurate and scientific information for efficient management and planning. Land use is the presentation of human activities on the land. So, land use information is very important to manage the city efficiently. We think that they can be integrated with land use information system. They make difficult to understand land use pattern by existing land use information, such as parcel's land category and building's use classification. The purpose of this study is to suggest the land use information system model for Tae-gu which can integrate land use information systematically. The basic components of land use information system are spatial reference files(parcels), land use information files, urban project files which are computerized by files and integrated in system. Finally, parcel based land use information system which users are the major components can be operationalized and improved the existing conditions of urban management.

高等學校 陸上評價의 平均評價와 回歸評價 適用에 관한 硏究 : 멀리뛰기를 중심으로

金鍾吉,朴贊弘 公州大學校스포츠科學硏究所 1999 스포츠科學硏究所論文集 Vol.- No.13

This study was about writing of a plan of athletic evaluation based on the methods of average and regressive evaluation for second grade student's satisfaction and achievement in D high school. It was used Microsoft Excel 97 program and Spss for MS Windows Release 6.1 program to data analysis. The result were as follows : 1) A correlation coefficent between long jump and height of student was 0.75 There was seen to very high correlation between. 2) The results showed that there was difference between groups in satisfaction test on the average and regressive evaluation. 3) There were showed significant differences between groups. Regressive evaluation group was higher satisfaction than average evaluation groups in the satisfaction test. 4) There were showed significant differences among height groups(long, middle, short) in the reasonable test of average evaluation. Long height students were higher satisfaction than short height students. 5) There were showed significant differences among height groups(long, middle. short) in the satisfaction test of average evaluation. Long group students showed higher satisfaction. 6) There were showed significant differences among height groups(long, middle, short) in the reasonable and satisfaction test of regressive evaluation. Short height students showed higher satisfaction to regressive evaluation. 7) It were should significant differences among herght groups(long, middle, short) satisfaction test of regressive evaluation short height students showed higher satisfaction to regressive evaluation. 8) There were showed changeable ratio 41.5%∼50.0% between groups in the comparative analysis of two evaluations.

세가지 니켈 티타늄 파일의 휨과 비틀림 조건에서의 응력 분포에 관한 3차원 유한요소 연구

김태오,이찬주,김병민,박정길,허복,김현철 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.4

이 연구의 목적은 세가지 니켈-티타늄 파일의 휨과 회전 조건 하에서의 응력 분포를 유한요소 모형을 이용하여 비교하는 것이다. ProFile .06/#30, ProTaper와 ProTaper Universal의 F3파일을 마이크로컴퓨터 단층촬영을 하고 reverse engineering을 통하여 세 니켈 티타늄 파일의 구조를 얻고 삼차원 유한요소모형을 제작하였다. 니켈 티타늄 합금의 비선형적인 물리적 성질을 반영하고 ABAQUS 프로그램을 이용하여 휨과 회전 조건 하에서의 기계적인 움직임을 수학적으로 예측 분석하였다. U-형태의 단면 구조를 가진 ProFile이 모형 가운데 가장 좋은 휨 성질을 나타냈다. 동일한 휨량 조건에서는 볼록한 삼각형 단면의 ProTaper가 다른모형보다 많은 힘을 필요로 하였으며, 반면에 가장 높은 von Mises 응력은 ProTaper Universal의 단면에서 움푹 파인 부위에 집중되었다. ProFile 모형은 동일한 크기의 회전력에 대해 가장 큰 응력 집중을 U-형 구 부위에 나타냈다. ProTaper 모형은 다른 모형에 비해 동일량을 비틀기 위해 더 많은 힘을 필요로 하였으며, 반면에 동량의 비틀림에서는 가장 높은 von Mises 응력이 ProTaper Universal의 단면에서 움푹 파인 부위에 집중되었다. Flexibility and fracture properties determine the performance of NiTi rotary instruments. The purpose of this study was to evaluate how geometrical differences between three NiTi instruments affect the deformation and stress distributions under bending and torsional conditions using finite element analysis. Three NiTi files (ProFile .06 / #30, F3 of ProTaper and ProTaper Universal) were scanned using a Micro-CT. The obtained structural geometries were meshed with linear, eight-noded hexahedral elements. The mechanical behavior (deformation and von Mises equivalent stress) of the three endodontic instruments were analyzed under four bending and rotational conditions using ABAQUS finite element analysis software. The nonlinear mechanical behavior of the NiTi was taken into account. The U-shaped cross sectional geometry of ProFile showed the highest flexibility of the three file models. The ProTaper, which has a convex triangular cross-section, was the most stiff file model. For the same deflection, the ProTaper required more force to reach the same deflection as the other models, and needed more torque than other models for the same amount of rotation. The highest von Mises stress value was found at the groove area in the cross-section of the ProTaper Universal. Under torsion, all files showed highest stresses at their groove area. The ProFile showed highest von Mises stress value under the same torsional moment while the ProTaper Universal showed the highest value under same rotational angle.

만곡 근관에서 삼각 혹은 장방형 단면 구조의 니켈-티타늄 파일 응력 분포에 관한 3차원 유한요소 연구

김현주,이찬주,김병민,박정길,허복,김현철 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.1

이 연구의 목적은 3차원 유한요소 모형 분석을 이용하여 삼각 대칭형과 S형태의 단면 및 변형된 사각 형태인 장방형 단면으로 분류되는 네 종류의 니켈티타늄 파일이 만곡 근관 적용 시의 응력 분포를 비교하는 것이다. 삼각 대칭형 단면 구조의 ProFile #30 / .06과 HeroShaper #30 / .06,장방형 단면구조의 Mtwo #30 / .05와 NRT #30 / .06 파일을 마이크로컴퓨터 단층촬영을 하고 reverse engineering을 통하여 파일의 구조를 얻고 삼차원 유한요소모형을 제작하였다. 모형 근관 내에서 파일이 근관장 끝까지 진입하여 회전할 때 발생하는 von Mises 응력 분포 및 파일의 제거후의 잔류 응력의 분포양상을 ABAQUS 프로그램을 이용하여 비교하였다. 근관 내 회전 시에 발생하는 응력을 관찰하였을 때 NRT 파일에서 가장 큰 응력을 나타냈으며 , 각 파일에서의 최고 응력과 최저 응력을 비교하였을 때 Mtwo파일에서 가장 큰 차이가 나타났다. 응력의 내부 분포 경향을 보았을때 장방형 구조의 단면을 가진 Mtwo 및 NRT 파일에서 불연속적인 응력의 집중 부위가 관찰되었으며 , 근관 외부로 파일을 제거하여 탄성 회복이 일어난 후의 잔류 응력도 NRT 파일에서 가장 높게 나타났다. 이상의 결과로 유추할 때, 삼각대칭 단면 구조를 가진 파일보다 S-형태의 단면과 변형된 사각 형태의 단면 등의 장방형 단면 구조의 파일이 파절의 위험성이 더 클 것으로 사료된다. The purpose of this study was to compare the stress distributions of NiTi rotary instruments bascd on their cross-sectional geometries of triangular shape-based cross-sectional design. S-shaped cross-sectional design and modified rectangular shape-based one using 3D FE models. NiTi rotary files of S-shaped and modified rectangular design of cross-section such as Mtwo or NRT showed larger stress change while file rotation during simulated shaping. The stress of files with rectangular cross-section design such as Mtwo, NRT was distributed as an intermittent pattern along the long axis of file. On the other hand, the stress of files with triangular cross-section design was distributed continuously. When the residual stresses which could increase the risk of file fatigue fracture were analyzed after their withdrawal, the NRT and Mtwo model also presented higher residual stresses. From this result, it can be inferred that S-shaped and modified rectangular shape-based files were more susceptible to file fracture than the files having triangular shape-based one.

암사슴의 뿔 발생 인공 유도가 번식에 미치는 영향

김상우,서길웅,상병찬,이규승 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.1

This study was conducted to investigate the antler induction rate and production by artificial induction of antlerogenesis using CaCl_(2) injection on both periosteum around area of horn development for the frontal bone of a female elk deer which do not have an antler. The results obtained from eleven deers for verifying effect of the female's antler induction on reproduction are as follows: The antler development induction by CaC1_(2) injection is higher on the treatments of 30 and 50 % of CaCl_(2) injection than those on the treatments of 15 %. The antler production is higher on the 30 % CaCl_(2) injection than those of 15 and 50 % CaCl_(2) injection. For 30 % CaCl_(2) injection, the antler production is higher in 1.5 and 2.0 ml of % CaCl_(2) injection than the other injection level. After the induction of antler development, the birth rate is not changed as of 75-100 %, while the regeneration rate of the antler which was not constant in approximately 45 % for five among eleven female deer. With these results, we assume that the injection concentration and amount of CaCl_(2) injection are around 30 % and 1.5 and 2.0 ml level which can be not only most effective conditions for the antler induction rate and production, but also these conditions do not influence the reproduction during the period of the female elk's antler development induction.

항균성 펩타이드인 Mastoparan B의 살조효과

서정길,김찬희,배윤정,문호성,김근용,박희연,윤호동,김창훈,변대석,홍용기,박남규 한국어병학회 2003 한국어병학회지 Vol.16 No.3

Mastoparan B (MPB)는 벌독으로부터 정제된 양친매성α-helical 구조를 취하면서 14개의 아미노산 잔기로 구성된 염기성 항균성 펩타이드로서 여러 가지 생물막과 작용한다. 본 연구에서는 우리 나라 연안의 적조 (HABs, harmful algal blooms)를 일으키는 4종의 적조생물 (Alexandrium tamarense, Chattonella catenatum)에 대한 MPB의 살조효과를 조사하였다. MPB의 4종의 적조생물에 대한 살조효과는 31.3㎍/㎖에서 세포의 lysis또는 ecdysis와 같은 형태로 현미경으로 관찰할 수 있었다. 또한 MPB는 C. marina 및 C. polykridorides에 대해서 A. tamarense와 G. catenatum보다 더욱 강한 살조효과를 나타내었다. 이러한 MPB의 HABs에 대한 살조효과연구는 새로운 살조물질을 개발하기 위한 자료가 될 것으로 생각된다. Mastoparan B (MPB), an antimicrobial cationic peptide isolated from the venom of the hornet Vespa basalis, is a basic amphipathic a-helical peptide composed of fourteen amino acid residues. In this study, we have investigated the algicidal effect of MPB against hatmful algae blooms (HABs) casative Alexandrium tamarense, Chattonella marina, Cochlodinium polykrikoides and Gymnodinium catenatum. The algicidal effect of MPB showed in the concentration of 31.3 ㎍/㎖ to 500 ㎍/㎖ against 4 HAB species and observed cell lysis or cell ecdysis by microscopy. MPB reacted more sensitive to C. marina and C.polykrikoides than A. tamarense and G. catenatum. The algicidal study of MPB against HABs will provides much insight into development of new algicidal substances.

間歇的 運動에 의한 脫水 및 水分攝取의 生理的 效果

朴哲浩,朴吉俊,李相于,金永明,朴贊熙,玄松子,呂南會,朴相甲,金榮俊 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

This study aims at revealing the physiological responses of dehydration (DH) and rehydration (RH) in intermittent exercises at the work intensity of 70% HR max. First, with general student public, three times of exercise (each for 20 minutes) at the given work intensity were taken, with a break for 25 minutes respectively. Their heart rate, rectal temperature and plasma electrolyte concentration both DH and RH were measured. Second, in two groups of athletes and non-athletes, 9 rounds of exercise (for 100 minutes) and 8 breaks (for 60 minutes) were taken, with RH forced 10 times to compensate for the subjects' water loss. Their change in sweat loss and plasma electrolyte concentration as well as the IVDP(Intensive Voluntary dehydration Phenomenon) were experimented. The summary of this research follows. 1) Mean heart rate and rectal temperature in intermittent exercises were higher at DH than at RH, growing up at the increasing level of DH. 2) RH saw no change in the plasma concentration of Na+, K+ and Cl-, while DH observed a significant increase. 3) HCO₃made a significant decrease at DH before growing up. 4) Mg++ had no change, while Ca++ increased significantly at RH and DH. 5) Lactate showed an increase with significance at RH and DH, especially greater at DH. 6) Osmotic pressure increased meaningfully at DH. 7) Anion gap increased significantly at DH and RH. 8) On the other hand, when the forced RH was held, the group of athletes had greater sweat loss per body surface area than that of non-athletes. 9) The athletes' plasma concentration of Na+ and Cl- revealed a clear decrease. 10) There was seen no significant change in the plasma concentration of K+, Mg++ and Ca++ in both groups. 11) The IVDP occurred at the RH of 2.3ℓfor athletes and more than 2.5ℓfor no-athletes.

Propantheline Bromide의 安定性에 關한 硏究

沈應基,李海彬,金吉洙,姜讚淳,李福姬 國立保健硏究院 1977 국립보건연구원보 Vol.14 No.-

의약품중 잔류유기용매 시험법 확립에 관한 연구

고용석,강찬순,최보경,김혜수,홍정희,최명신,김상현,장성재,김길수 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

Headspace-GC(딘5-GC)를 이용하여 ICH 잔류웅매 가이드라인 class 1, 2에 속하는 28종의 잔류유기웅매 분석방법을 연군한 결과 SPB-5, BB-WAX column을 동시 이용하여 각각을 확인, 정량할 수 있었다.또한 염의 참가효과, 평형시간,평형온도가 headspace분석에 미치는 영향을 검토한 결과 평형 시간 30분,평형온도 85℃,Na₂SO₄Ig을 첨가하여 시험할 때 최적 부넉조건을 나타내었다. 회수율은 1,1-achloroethene(68.3%)를 제외하고 90.9 ~ 114.5%로 패체적으로 양호하였다. 따로 HS-GCJECD, DB-524 column을 이용하여 9종의 잔류유기용매에 대하여 각각의 검랸선을 작성하고 검출한계를 구하였다. 실제 의약품 원료 10종및 제제 5종에 적용시킨 결과 모두 불검출되었으며 본 시험법은 의약품중의 잔류유기용매 분석에 적용할 수 있는 방법이라고 판단된다. The headspace-fC/FID(HS -GC/FID) method was performed for test method developnlent of residu;31 organic solvents in pfrarmaceuticals. Using SPB-S and BB-WAXcolumn, 28 kinds of solvents iri ICH residual sof)·ents guidetine class 1, 2 couBd be individuallt-identified and quantitated. The foIBowing residoal soIYents were not detected by the headspaceinjection condition : N,N-Cmethylacetamide, N,N-dimeth)rlformamide, ethyfeneglycol, formamide,2-methoryethanot, N-rnethylpyrrolidone, suBforane. The effects of the addition of salts,equilibration time, and equilibration temperature on headspace analt·sis were invesugated. Theoptimum conditions weiFe obtained with addtion of Ifa2s04 19 as a salt, simultaneously. thetime and temperature of equitibration were 30min and 8i'f, respectivety. The recovery havefound between 90.9 and 114.5% except 1,1-dichloroethene(fi8.3%). Using DB-624 column &HS-GC/:ECD method, 9 kinds of residual solvents could be individually identified andfuantitated. This HS-GC method can be applied to test the residua3 organic solvent in thepharmaceuticals.