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Spent coffee as a rich source of antioxidative compounds
최보경,고은미 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.4
Antioxidant activities and major antioxidants were investigated in the methanolic extracts of roasted and spent coffee to evaluate the feasibility of spent coffee as a source of functional ingredients. Phenolic compounds, such as gallic acid, protocatechuic acid, and chlorogenic acid, and nitrogenous compounds, including trigonelline and caffeine, were identified. Caffeine was the most abundant compound, followed by chlorogenic acid.Despite the significant reduction of antioxidants, 2,2,-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was retained in more than 95% of roasted coffee. The retentions of superoxide dismutase (SOD)-like activity and ferric reducing antioxidant power (FRAP) were 65–90 and 46–60%, respectively. Gallic acid had a positive correlation with SOD-like activity, whereas protocatechuic acid positively correlated with FRAP, suggesting that the major compounds contributing to each antioxidant activity are different. These results show that spent coffee can be used as an antioxidant source for functional foods and cosmetic products to improve antioxidant properties.
한국 전공의들의 직장 내 차별 경험과 심리적 스트레스, 우울감, 자살 생각과의 연관성
최보경,김지환,김승섭 한국보건사회연구원 2018 保健社會硏究 Vol.38 No.2
Few research has been conducted about the association between workplace discrimination and mental health outcomes among medical residents. This study sought to 1) assess the prevalence of workplace discrimination; and 2) examine the association between workplace discrimination and mental health outcomes (i.e. psychological distress, depressive symptoms, suicidal ideation) among medical residents, using a cross-sectional dataset of 1,155 Korean medical residents in 2014. Experience of workplace discrimination over the past year and its reason (i.e. gender, educational background, age, appearance, grade, and others) were assessed. Our analysis found that 27.1% (N=216) of male and 42.9% (N=153) of female medical residents experienced workplace discrimination over the past year. Among medical residents who experienced discrimination at work, the most common reasons for discrimination was educational background (32.4%) for male, whereas it was gender (69.3%) for female medical residents. Experience of workplace discrimination showed statistically significant association with psychological distress (PR: 2.27, 95% CI: 1.65-3.12), depressive symptoms (PR: 1.56, 95% CI: 1.32-1.83), and suicidal ideation (PR: 1.61, 95% CI: 1.04-2.49) among male whereas statistically significant association was observed only in the analysis of depressive symptoms (PR: 1.22, 95% CI: 1.00-1.48) among female residents. This study found that workplace discrimination was prevalent among Korean medical residents, and it was associated with mental health problems. 본 연구는 2014년에 전국 25개 전문과목 전공의 1,155명을 대상으로 수행된 단면연구 자료를 분석하여 다음의 연구목표를 달성하고자 했다. 첫째, 전공의들의 1년 동안 직장 내 차별 경험과 차별 경험의 요인은 무엇인지 확인한다. 둘째, 이와 같은 직장 내 차별 경험이 전공의들의 정신건강(심리적 스트레스, 우울감, 자살 생각)과 어떤 연관성을 가지는지 남녀로 나누어 검토한다. 분석 결과, 남성 전공의 798명 중 216명(27.1%), 여성 전공의 357명 중 153명(42.9%)이 지난 1년 동안 직장 내 차별을 경험한 것으로 보고하였다. 차별을 경험한 전공의 중 남성 전공의는 출신학교(32.4%)와 나이(27.3%), 여성 전공의는 성별(69.3%)과 출신학교(30.7%)를 차별 경험의 주된 요인으로 보고하였다. 성별을 나누어 검토한 결과, 남성 전공의에서는 직장 내 차별 경험과 심리적 스트레스(PR: 2.27, 95% CI: 1.65-3.12), 우울감(PR: 1.56, 95% CI: 1.32-1.83), 자살 생각(PR: 1.61, 95% CI:1.04-2.49)이 통계적으로 유의한 연관성을 보였다. 반면 여성 전공의에서는 직장 내 차별 경험과 우울감(PR: 1.22, 95% CI: 1.00-1.48)과의 연관성만이 통계적으로 유의한 것으로 나타났다. 본 연구는 전공의들이 경험하는 직장 내 차별이 정신 건강 문제의 원인이 될 수 있음을 제시하는 첫 연구로, 병원 내 차별 문제와 전공의의 정신건강 문제를 개선할 수 있는 정책 수립의 근거가 될 것으로 기대한다.
≪墨子≫에서 보이는 명命에 대한 비판의식과 통제 가능성
최보경 고려대학교 중국학연구소 2024 中國學論叢 Vol.- No.84
The purpose of this study is to demonstrate Mozi criticizing Ming命 and controlling life in situations when war or disaster occurs. We often blame fate when we continually experience sudden events and situations when it is impossible to perform through our own will, or various situations that cannot be explained by causality. Unpredictable situations likely lead to resignation and arbitrary judgment. However, Mozi seek to eliminate the tendency of the obsession with Ming命 by providing the belief that external circumstances can be controlled. Rational judgments or actions help us escape from fatalism. Sanbiao三表, Jianxiangai兼相愛 and Jiaoxiangli交相利 are expected that rational judgment and moral standards will enable people to control their lives in situations such as war and disaster. I aim to organize my thesis in the following manner. First, I seek to confirm Mozi's criticism of fatalism. Moreover, I will discuss the need for Sanbiao三表 and deliberation. Finally, I will explore how Jianai兼愛 makes life bearable and controllable in disasters.
권력과 정치적 권위의 문제에서 바라 본 墨子의 정치사상
최보경 고려대학교 중국학연구소 2022 中國學論叢 Vol.- No.76
The aim of this paper is to study political thought of Mozi on power and political authority. Political thought of Mozi is the establishment and operation of a political system based on Shangtonglun(尙同論). Shangtong(尙同)'s logic should respect and follow the opinions of superiors, which have the return to feudalism centered at Tianzi(天子) and a vertical characteristics of the upper and lower. Therefore the challenge arises from two aspects. First, it did not reflect the political landscape at that time. Second, it is in conflict with his ethical ideology[兼愛]. These problems can be solved when political thought of Mozi is interpreted in terms of power and political authority. This becomes the theoretical basis for solving the two difficulties implied in Shangtonglun(尙同論). First, since the logic of homology is also applied to Tianzi(天子), the power of Tianzi(天子) can secure political authority by Tian(天). The attribution of Tian(天) is a premise that can induce voluntary obedience of the people because it is unselfish. Second, Tianyi(天意) is Jianai(兼愛). Tianzi(天子) must observe the horizontal ethical principles of Jianai(兼愛), so the power of Tianzi(天子) guarantees morality. As a result, the power of Tianzi(天子) will secure autonomous obedience and morality through the symbol of Tian(天).
Thermal characterization of PAN and pitch-based carbon fibersaccording to various heat treatments
최보경,국윤수,서민강 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0
The crystallization, exothermic, and electrochemical properties of PAN/pitch-based carbon fibers (CFs) with various temperatures were studied. The CFs were prepared from stabilized PAN and pitch-based carbon fibers at 500°C, 700°C, 900°C, and 1100°C with 60 min. The surface and structural properties of the CFs were determined by scanning electron microscope (SEM) and X-ray diffraction (XRD), respectively. The electrical conductivity was obtained by measuring the surface resistance with 4-pin probe method. The thermal properties of the CFs were studied by thermal conductivity measuring system.
최보경,이옥정,박윤경,임태효,김상단 한국방재학회 2016 한국방재학회논문집 Vol.16 No.5
In this study, the stormwater capture ratio and load capture ratio are actually estimated using TP monitoring data and SWMM modeling. From such ratios’ estimation, uncertainties involved in the existing stormwater and load capture ratios and the relative impact of these uncertainties on the performance evaluation of designed non-point sources pollution control facilities are quantified. The study area is a small drainage catchment in the Busan Noksan industrial zone in order to exclude the effect of unnecessary uncertainty caused by various land use patterns. An interlocking module between SWMM and Matlab is used to estimate efficiently model parameters. As a result, main uncertainty in designing non-point sources pollution control facilities is due from underestimation of the stormwater capture ratio. Hence, the present stormwater capture ratio should be improved. 본 연구에서는 총인 모니터링자료와 SWMM 모델링을 이용하여 강우유출수 처리비와 삭감대상부하비가 산정된다. 이를 통하여 강우유출수 처리비와 삭감대상부하비 산정에 포함된 불확실성과 이러한 불확실성이 설계된 비점오염저감시설의 성능평가에 미치는 상대적인 영향이 정량화된다. 대상지역은 부산광역시에 위치한 녹산공단의 소규모 배수분구를 선정하여 토지이용패턴에 따른 불확실성을 사전에 배제하고자 하였으며, SWMM을 이용한 모델링에서의 효율적인 매개변수 추정을 위하여 SWMM-Matlab 연동 모듈이 이용된다. 분석결과 우리나라 비점오염저감시설 설계 시의 주요 불확실성은 강우유출수 처리비의 과소산정으로부터 기인하고 있으며, 따라서 현재 사용되고 있는 강우유출수 처리비 공식의 개선이 필요함을 살펴볼 수 있다.
Flurbiprofen 용매침착물(溶媒沈着物)의 용출특성(溶出特性)에 관(關)한 연구(硏究)
최보경,용재익,Choi, Bo-Kyung,Yong, Jae-Ick 한국약제학회 1985 Journal of Pharmaceutical Investigation Vol.15 No.3
Dissolution characteristics of flurbiprofen solvent deposited on ${\alpha}-cyclodextrin$, ${\beta}-cyclodextrin$, lactose and corn starch were studied to evaluate the pharmaceutical aspects of solvent deposition method where drug was solvent deposited on the surface of excipients. In a solvent deposition system, the drug to excipient ratio and kind of excipient affect much on dissolution rates of flurbiprofen. The solvent deposition system formation was confirmed by scanning electron microscope. By increasing the amounts of matrix, it was possible to enhance the dissolution rate of flurbiprofen solvent deposition system. The amount of flurbiprofen dissolved from ${\beta}-cyclodextrin$ deposition system (1:10) at 60 minutes was enhanced 6.5 times in water and 28 times in simulated gastric juice compared with flurbiprofen alone. Flurbiprofen solvent deposited system (1:10) enhanced dissolution rate greater than inclusion complex and dispersion system.