소음인(少陰人) 태음병(太陰病) 심하비증(心下?證)의 병증약리(病證藥理) 고찰

서영광,이지원,이준희,최원철,이의주,고병희,Seo, Young-Kwang,Lee, Ji-Won,Lee, Jun-Hee,Choi, Won-Cheol,Lee, Eui-Ju,Kho, Byung-Hee 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3

1. Objective: Gastric Stuffiness (心下?證) in the Soeumin Taeeum symptomatology (少陰人 太陰病) in Sasang Constitutional Medicine shows an interesting evolutionary process. Originally found in the texts of Sanghanlun (傷寒論), the perspectives regarding the symptoms of Gastric Stuffiness were expanded by many medical scholars and Lee Jema. To comprehend the Jema's concept of Taeeum symptomatology and utilize his prescription clinically, it deserves to study on the Gastric Stuffiness in Donguisuseowon (東醫壽世保元). 2. Methods: Many texts including Sanghanlun (傷寒論) and Dongeuibogam (東醫寶鑑) were reviewed in order to track the evolutionary process concerning the symptoms of Gastric Stuffiness. Also, Lee Jema's works including the different versions of Donguisuseowon (東醫壽世保元) were reviewed to examine the development of Lee's concepts regarding the Gastric Stuffiness in the Soeumin Taeeum symptomatology. 3. Results and Conclusions: 1) Most of the previous concepts on Gastric Stuffiness were generally similar to those found in Sanghanlun, especially in that they addressed Yang deficiency of the middle triple energizeer as the central pathogenic process. 2) Lee Jema's views on the epigastric discomfort in the Soeumin Taeeum symptomatology evoloved over time and culminated in the finalized pathology and therapeutics appearing in his last work, the Shinchuk version of Donguisuseowon (東醫壽世保元). 3) 4 kinds of prescription which invented by Lee Jema to treat the Gastric Stuffiness in the Soeumin Taeeum symptomatology can be matched to the prescription of Sanghanlun respectively. However through evolutionary process of Jema's prescriptions, the indication of them expanded: not only to treat Gastric Stuffiness but to diverse symptoms of Soeumin.

간세포암과 하대정맥 막성폐쇄의 치료 후 호전된 백혈구파괴혈관염 1예

이준엽 ( Jun Yeob Lee1 ),이주원 ( Ju Won Lee1 ),이진욱 ( Jin Wook Lee ),박현준 ( Hyun Joon Park ),장국환 ( Gook Hwan Jang ),김다정 ( Da Jung Kim ),김선민 ( Sun Min Kim ),한병훈 ( Byung Hoon Han ),정규식 ( Gyoo Sik Jung ),김근태 ( 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.5

저자들은 하지 자색반과 고환 통증으로 내원한 알코올성 간경화증 환자에서 LCV의 원인 감별하는 과정에서 HCC와 하대정맥 막성폐쇄를 진단하고 이에 대한 치료 후 LCV의 호전된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Vasculitis is a heterogeneous group of diseases that destroy blood vessel walls by inflammation. Approximately half of vasculitis cases are idiopathic, but sometimes associated with genetic factors, medicines, chronic infection, autoimmune diseases, and malignancies. Although the mechanism remains unclear, vasculitis secondary to malignancy, also known as paraneoplastic vasculitis, has been reported. It is generally associated with hematologic malignancies rather than solid malignancies and commonly presents as leukocytoclastic vasculitis or polyarteritis nodosa. We experienced a case of leukocytoclastic vasculitis in a patient with hepatocellular carcinoma and membranous obstruction of the inferior vena cava. Here, we report this case with a brief review of literature. (J Rheum Dis 2015;22:322-326)

오존을 이용한 하수슬러지의 감량화와 안정화

이창근,황은주,강성재,빈정인,이병헌 한국물환경학회 2004 한국물환경학회지 Vol.20 No.3

In this study, ozone was adopted for the reduction and stabilization of waste sludge from the municipal sewage treatment plant. The waste sludge used in the experiments was primary sludge, excess sludge and a mixture of the two. The sludge cells and flocs were disrupted by ozonation resulting in the reduction of TSS and VSS concentrations. In the case of the primary sludge with a concentration of 20 gTS/L, the TSS and VSS concentrations were reduced 28%, 33% and the TCOD concentration was reduced 20% respectively. The consumption of ozone was 0.18 gO₃/gSS. In the case of the excess sludge with a concentration of 7.5 gTS/L, the TSS and VSS concentrations were reduced 37%, 41%, and the TCOD concentration was reduced 19% respectively. The consumption of ozone was 0.33 gO₃/gSS. In the case of the mixed sludge of 9.3 gTS/L, the TSS and VSS concentrations were reduced by 45%, 53%, and the TCOD was reduced 26% respectively. The desirable consumption of ozone was 0.27 gO₃/gSS. As ozonation proceeded, the level of SCOD increased due to the release of intracellular materials. However TCOD was reduced due to mineralization resulting from the transformation of organic materials to inorganic materials.

구개편도에 발생한 결핵

이병돈,강주원,장혁순,박철규,김장묵 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.1

Tonsillar tuberculosis, almost always secondary to pulmonary tuberculosis is very rare disease in otolaryngologic fields. Authors have experienced a case of tonsillar tuberculosis associated with miliary pulmonary tuberculosis. The patient had cough, sputum and sore throat for 1 month. On physical examinations, palatine tonsils were slightly hypertrophied, smoothly surfaced, but crypt ulceration or patches were not seen. Diffuse discrete nodules were seen in both lung fields by simple chest X-ray. In high resolution computed tomography, miliary tuberculosis was suspected and in pleural needle biopsy, granulomatous inflammaiton was diagnosed as tuberculosis. AFB smear of sputum was two positive. Histopatholoigic finding of right tonsil was consistent with tuberculosis. He was cured of it with antituberculosis medications for one year. We report the case with review of the literatures.

Er:YAG laser를 조사한 치근면의 변화에 관한 연구

이상현,김영준,김병국,정현주 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.4

This study was performed to evaluate the usability of Er:YAG laser for periodontal therapy. Forty dental root slabs (5x5x2mm^3) were prepared from human periodontally discased extracted teeth and grouped into 4 groups. 1)control (root planing only). 2)root planing and irradiated with laser at 30mJ. 3)root planing and irradiated with laser at 60mJ. and 4)root planing and irradiated with laser at 100mJ. The root slabs were embedded in resin block before laser treatment. Er:YAG laser was irradiated under water irrigation with the tip held perpendicular to the root surface in contact mode, After Er:YAG laser Irradiation or planing on the root surface, morphological changes have been observed under SEM, and the micro-hardness and Ca/P ratio were compared. 1. In the control group. the root surface showed the directional change caused by root planing instrumentation, and the presence of smear layer, and no exposure of dentinal tubule was observed. Laser irradiated group showed surface changes with rough dentin surface of niche and depression and dentinal tubule exposure by the elimination of smear layer. 2. The micro-hardness of root surface in the laser irradiated group was higher than the control group. The higher energy output was applied. the higher micro-hardness on root surface was resulted. 3. The higher energy output was applied, the higher Ca/P ratio was observed. The higher Ca/P ratio in 60mJ group and 100mJ group was statistically significantly compared to the control gloup and the 30mJ group These results suggest that Er:YAG laser Irradiation on the periodontally diseased root surface could remove smear layer and increase the micro-hardness on root surface and Ca/P ratio which contribute to enhance the acid resistance of periodontally treated root surface.

e-SCM의 전략적 구축 모형에 관한 연구

이종만,장주병 경복대학 2000 京福論叢 Vol.4 No.-

e-Business환경에서는 어플리케이션, 정보기술과 전략뿐만 아니라 SCM 또한 급변하고 있다. 본 논문에서는 공급사슬관리의 전략적 구축을 위해 세 가지 기본적인 e-SCM 모델을 제시하였다. 이 모델들은 B2B상에서 기업이 오늘날 SCM 구축을 위해서 출현기술들을 선택하는데 유용한 일반적인 방법들을 제시하고 있다. 본 연구에서 제시한 세 가지 e-SCM 모델은, 기업주도형 모델, 제3자 통합자형 모델, 실시간 지식 발견형 모델이다. 이러한 세 가지 e-SCM모델들은 e-SCM 구축을 지원하는데 유용할 것이며, 특히 가상기업 환경에서는 더욱 더 유용할 것으로 생각된다. e-Business presents a landscape of applications subject to high-velocity change, both technical and strategic, and the SCM function is no exception. In this paper, we outline three basic e-SCM model to support strategic implementation of supply chain management. The models represent the most common ways that companies choose today to utilize emerging technologies for business-to-business SCM. We suggest that three basic categories of e-SCM solutions, the "Do-It-Yourself', "Third-Party Integrator" and "Real-Time Knowledge Discovery" models. This three e-SCM models useful to support e-SCM implementation, especially for virtual enterprises environment.

시장개혁과 공정거래위원회의 역할

이병주 한국산업조직학회 2004 産業組織硏究 Vol.12 No.1

본 논문의 목적은 우리나라의 시장개혁을 위해 공정거래위원회가 중점적으로 추진해야 할 과제와 역할을 정립하고자 하는 것이다. 시장의 현황에 대한 객관적인 평가를 토대로 시장개혁의 비전과 목표를 설정하고 이를 달성하기 위한 정책과제를 구체적으로 제시하였다. 시장은 잘하는 경제주체와 잘못하는 경제주체를 차별화하는 장치이다. 소비자, 채권자, 주주, 투자자, 근로자, 잠재적 CEO 등 시장에 존재하는 각종 이해당사자들을 더 많이 양성하고 그 힘을 강화하여 시장의 차별화 기능이 한층 더 효율적으로 작동되도록 각종 제도와 정책을 보완·발전시켜 나가야 한다. 시장개혁은 공정하고 투명한 경제시스템의 확립을 위한 것으로 "타자위해의 원칙"(harm principle)에 따라 남에게 해를 끼치지 않는 한 자유로운 시장 활동을 보장하고 정부 직접규율보다는 시장 자율감사를 중시하는 방향으로 일관성 있게 추진되어야 한다. 시장개혁이 성공적으로 추진되기 위해서는 대기업집단의 소유지배구조가 개선되고 기업내·외부 견제시스템이 보완되어 산업자본의 금융지배에 따른 폐해가 차단되어야 한다 동시에, 시장경쟁이 제고되도록 담함 등에 대한 규제를 강화하고 경쟁제한적 규제를 철폐하는 한편, 사소활성화 등을 통해 불공정행위에 대한 사회적 감시기능을 강화해 나가야 한다. The purpose of this article is to present the major task and function of Korean Fair Trade Commission(KFTC) which aims to increase transparency and fairness of the market. The goal of market reform is to increase efficiency in resource allocation and enhance the status of the Korean economy by establishing a fair and transparent economic system. Based on the objective evaluation index measuring transparency, fairness and competition of business and market that is developed by the Korean Development Institute, specific policy measures to improve corporate ownership and governance structure of large business conglomerates and market s self-monitoring mechanism are suggested.

杜甫 '秋興八首' 堯解

李丙疇 東國大學校 1964 論文集 Vol.1 No.-

太陰調胃湯이 白鼠의 肥滿症 및 誘導肥滿細胞에 미치는 效果

田炳薰,金敬堯,李基珠 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.1

太陰調胃湯은 四象體質中 太陰人에 적용되는 處方으로 그 구성은 주로 祛濕, 祛痰하는 藥物로 이루어져있다. 韓醫學에서 肥滿의 병리기전은 주로 濕痰이 체내에 전체된 것으로 보고 있는데 太陽調胃湯의 處方구성은 이와같은 體內濕痰을 제거하는데 알맞음을 볼 수가 있다. 이에 太陽調胃湯이 gold thioglucose와 高脂肪食餌로 誘發한 肥滿 마우스에 미치는 效果와 前指肪細胞의 增殖과 分化에 미치는 影響을 실험하고 관찰한 결과 다음과 같은 결과를 볼 수 있다. 1. 太陽調胃湯은 前脂肪細胞(3T3-L1 세포)의 增殖과 分化를 抑制한다. 2. 細胞內 脂質蓄積을 誘導하는 酵素와 中性脂質의 細胞內 蓄積을 抑制하는 效果가 認定된다. 以上의 結果로 보아 太陰調胃湯은 四象體質中 가장 肥濕하기 쉬운 太陽人의 肥滿治療에 有用할 것으로 思料된다. Effects of Taeyeumjoweetang on the obesity of mouse induced by gold thioglucose. It is researched to elucidate the effects of Taeyeumjoweetang on the obesity of mouse induced by gold thioglucose and the diifferentiation and growth of preadipocyte, 3T3-L1 cell. The result were as follows. 1. Taeyeumjoweetang extract improved the blood level of transaminase changed by the obesity of mouse induced by gold thioglucose. 2. Taeyeumjoweetang extract inhibited the increase of liver fat and body fat induced by the obesity of mouse induced by gold thioglucose. 3. Taeyeumjoweetang extract inhibited the increase of body weight induced by the obesity of mouse induced by gold thioglucose. 4. Taeyeumjoweetang extract inhibited the growth of undifferentiate preadipocyte 3T3-L1. 5. Taeyeumjoweetang extract showed the effects of inhibition on the differentiation of preadipocyte 3T3-L1. The above results suggested that the Taeyumjoweetang extract may be used on the obesity induced by the overgrowth and differentiation of adipocyte, and the accumulation of fat in liver and body.

한국인 정신분열병과 도파민 D5 수용체 유전자 연합연구

이민수,조주연,박두병,김준모 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

본 연구는 도파민D5 수용체 유전자와 정신분열병 병인과의 상관성을 밝히기 위하여 한국인 정신분열병 환자군 100명과 정상대조군 100명에서 다형성의 분포를 중합효소연쇄반응을 이용하여 연합연구를 시행하였다. 도파민 D5 수용체 유전자의 대립유전자는(CT/GT/GA)n의 반복으로 구성된 154, 152, 150, 148, 146, 144, 142, 140, 138, 134염기 쌍을 가진 11가지 종류였고 환자군과 정상대조군사이에 대립유전자의 분포는 통계적으로 유의한 차이를 보였다. 각각의 대립유전자 빈도는 환자군에서 대립유전자 A10이 유의하게 감소되어 있었다. 환자군과 정상대조군의 유전자형 분포는 두 군간에 유의한 차이는 없었다. 본 연구의 결과는 도파민 D5 수용체 유전자가 한국인 정신분열병 발생의 취약성에 기여할 가능성이 있다는 것을 제시하지만 본 연구의 결과만으로는 이 유전자부위를 정신분열병의 유전적 결정인자로 결론 내리기는 어려우며 앞으로 더 많은 연구대상을 이용하여 이 도파민 D5 수용체 유전자부위에 대해 본 연구결과를 확인하는 연구가 계속적으로 이루어져야 할 것으로 생각된다. Objective : This study was performed to define the genetic relationship between the microsatellite (CT/GT/GA)n polymorphism for the dopamine D5 receptor gene and schizophrenia. An association study in 100 schizophrenic patients and 100 normal controls of Korean was made by means of using polymerase chain reaction. Results : The microsatellite(D5(CT/GT/GA)n) had 11 alleles. These was a significant difference in the allele distribution between schizophrenic and normal controls(p〈0.05). In schizophrenic patients, the frequency of allele A10 was decreased. As to the genotype distribution, there was no difference in both groups. Conclusions : This finding suggests that dopamine D5 gene is likely to be related to the development of schizophrenia in Korea but with only this result, we cannot come to the conclusion that this genetic locus is the genetic determinant of schizophrenia. Further studies of dopamine D5 receptor genetic locus that can confirm this result should be made.