Rat의 성주기에 따른 난포의 수와 형태변화

이의주,곽수동,Lee, Yoi-joo,Kwak, Soo-dong 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.3

This study was designed to investigate the number of the growing and mature follicles in each stage of estrus cycle in mature rats. Eighteen mature rats(Sprague-Dawley, initially 190~230gm) were randomly alloted into 4 groups(proestrus, estrus, metestrus, and diestrus) according to estrus cycles. The uteri and ovaries of rats were collected and then alternative sections of paraffin embedding ovaries were stained with H-E. Numbers of large, middle and small follicles or only large and middle follicles from secondary and tertiary follicles were investigated by LM photography of preparations. Small follicles were defined as secondary follicles with 2~5 cell layers of granulosa cells surrounding the oocyte, and middle follicles were defined as secondary follicles with more than 5 cell layers or with early signs of antral cavity or with more than one small cleft on either side of the oocytes and large follicles were defined as tertiary follicles with a single medium or large antral cavity. The number of follicles in a pair ovary per rat was appeared to be ranged from 207 to 370 and the mean number of these follicles was $270.4{\pm}52.6$ and the mean number of follicles per ovary was $134.9{\pm}32.0$. The mean number of large, middle and small follicles per ovary was appeared to be $16.4{\pm}4.4$($12.2{\pm}3.3%$), $36.2{\pm}8.6$($26.8{\pm}6.4%$), and $82.7{\pm}24.0$($61.3{\pm}17.8%$), respectively. The mean number of large and middle follicles in each stage group of estrus cycle was appeared to be $17.8{\pm}2.1$ and $38.3{\pm}7.4$ at proestrus stage group, $15.7{\pm}5.2$ and $38.0{\pm}10.0$ at estrus stage group, $16.5{\pm}3.5$ and $33.8{\pm}7.0$ at metestrus stage group, $16.7{\pm}5.8$ and $29.7{\pm}5.5$ at diestrus group, respectively. In histological findings of large follicles during each estrus cycle, the large follicles in proestrus group contain single small antrum, thick granulosa cell layers, and were $300{\sim}500{\mu}m$ in diameter and were growing follicles with PCNA-positive cells in the granulosa cell layers, and other luteinizing follicles of proestrus cycle stage were decreased in size and were thicker in wall thickness and more luteinized than those in metestrus and diestrus stage groups. The large follicles in estrus stage group contain thick granulosa cell layers and nonprominent cumulus-oocyte complexes in antrum, and were $400{\sim}700{\mu}m$ in diameter and were growing follicles with PCNA-positive cells in the granulosa cell layers. The large follicles in metestrus and diestrus stage groups contain enlarged antrums, thinner layers of walls and prominent cumulus-oocyte complexes, and were $700-950{\mu}m$ in diameter, and were nongrowing follicles without PCNA-positive cells or another large follicles contain cells with dark stainability and distinct boundary.

사상변증내용(四象辯證內容) 설문조사지(設問調査紙)(I)의 타당화(妥當化) 연구(硏究)

이의주,고병희,송일병,Lee, Eui Ju,Ko, Byung Hee,Song, Il Byung 사상체질의학회 1995 사상체질의학회지 Vol.7 No.2

This study was conducted for the purpose of finding out an objective classification method for Sasang Constitutional medicine, which divides people into 4 groups of constitution and presents comprehensively physiology, pathology, diagnosis, therapy and recuperation regarding each constitution. Questionnaire of Sasang Constitution Classification(I) was administered to 328 inpatients at Kyung Hee Oriental Medicine Hospital. Data was collected during 10 months from June 1994 to Mar. 11, 1995. For the purposes of this study, the collected data was analyzed by crosstabs, variation analysis, and discrimination analysis. The analyzing program was SPSS PC+V4.0. For the purposes of this study, the collected data was analyzed by crosstabs, cariation analysis, and discrimination analysis. The analyzing program was SPSS PC+V4.0. The results were as follows : 1. There was significant differences of each group scales through variation analysis. The questions of each group had Sasang constitutional diagnostic discrimination abilities 2. The diagnostic discrimination abilities(Hit-ratio=56.10%) of the Questionnaire for Sasang Constitution Classification(I) were found to have over 20% improvement than the propotional chance criteria(33.3%), Especially, Hit-ratio for $So{\breve{u}}m$-In(63%) was higher than that of SoYang-In(55%) and $Ta{\breve{e}}um$-In(56.3%). 3. Through discrimination analysis on good questions of each group, the diagnostic discrimination abilities of the Questionnaire for Sasang Constitution Classification(I) was 57.93%. 4. This would be on the ground that the Questionnaire for Sasang Constitution Classification(I) could be used as a tool for Sasang constitution classification.

갑오본(甲午本)(구본(舊本))과 신축본(辛丑本)(인본(印本))을 중심으로 한 소음인(少陰人) 병증(病證)과 소양인(少陽人) 병증(病證)에 관한 고찰(考察)

이의주,고병희,송일병,임진희,Lee, Eui-Ju,Koh, Byung-Hee,Song, Il-Byung,Lim, Jin-Ny 사상체질의학회 2001 사상체질의학회지 Vol.13 No.2

1. Purpose 'Gu-Bon' of ${\ulcorner}$Soose Bowon${\lrcorner}$ found lately was written in 1940, through comparing with 'Gu-Bon' and 'In-Bon'. In 'Gu-Bon' and 'In-Bon', there are many different contents. The aim of the present study was to find changes of Dong-Mu's recognition on Symptom of Soeumin's Disease and Soyangin's Disease from 1894 to 1900 2. Methods Comparing with 'Gu-Bon' and 'In-Bon' on Symptom of Soeumin's Disease and Soyangin's Disease, Mechanism . region . main symptom and treatment of Soeumin's Disease and Soyangin's Disease are arranged. and changes of Dong-Mu's recognition on Symptom of Soeumin's Disease and Soyangin's Disease from 1894 to 1900 was found 3. Results 1) In 'Gu-Bon' of ${\ulcorner}$Soose Bowon${\lrcorner}$, Dong-mu recognized Symptom of Soeumin's Disease and Soyangin's Disease, mainly through the conception of 'ventral-dorsal--interior-exterior' and 'Main Qi of life protection' 2) In 'In-Bon' of ${\ulcorner}$Soose Bowon${\lrcorner}$, Dong-mu recognized Symptom of Soeumin's Disease and Soyangin's Disease, mainly through the conception of 'ventral-dorsal-interior-exterior' and 'Ascending of Yang-Qi and Descending of Yin-Qi' 3) In 'Gu-Bon' of ${\ulcorner}$Soose Bowon${\lrcorner}$, Symptom of Soeumin's Disease was classified into 'Taeyang Disease' and 'Yang-myoung Disease'. But In 'In-Bon' of ${\ulcorner}$Soose Bowon${\lrcorner}$, Symptom of Soeumin's Disease was classified into 'Mang-yang' and 'Ul-guang'

책갈피산책 - 이제마의 "동무유고"를 읽고

이의주,Lee, Ui-Ju 대한출판문화협회 2000 출판저널 Vol.273 No.-

확산화염의 비정상 거동과 국소 소화에 관한 연구 ( An experimental study on the unsteady behavior of strained diffusion flames )

이의주,오광철,신현동 대한기계학회 1998 대한기계학회 춘추학술대회 Vol.- No.-

동무(東武) 이제마(李濟馬)의 인간관(人間觀)에 관한 연구(硏究) - "동의수세보원사상초본권(東醫壽世保元四象草本卷)"을 중심으로 -

이의주,고병희,송일병,임진희,Lee, Eui-Ju,Koh, Byung-Hee,Song, Il-Byung,Lim, Jin-Ny 사상체질의학회 2003 사상체질의학회지 Vol.15 No.2

1. Objects of a study Dong-mu emphasized knowing who he or she is to treat disease, so this parer was written to summarize Dong-mu's thought on human 2. Methods of a study ${\ulcorner}Dongyi$ Suse Bowon Sasang $Choboguon{\lrcorner}$ is Dong-Mu's early writing, is composed of three chapters, which are ${\ulcorner}$Won-in$(原人)${\lrcorner}$ . ${\ulcorner}$Byung-byun(病變)${\lrcorner}$ . ${\ulcorner}$Yak-bang(藥方)${\lrcorner}$ . This is chiefly written on human, so this paper was written by summarizing Dong-mu's general and constitutional thought on human in ${\ulcorner}Dongyi$ Suse Bowon Sasang $Chobonguon{\lrcorner}$ 3. Results and Conclusion 1. Dong-mu's viewpoint of human in ${\ulcorner}Dongyi$ Suse Bowon Sasang $Chobonguon{\lrcorner}$ is viewpoint of human in the base of 'Human Nature(人性)-Human Form(人形)' and viewpoint of human in the base of 'Affairs-Mind-Body-Objects(事心身物)'. 2. The general viewpoint of human suggested in ${\ulcorner}Dongyi$ Suse Bowon Sasang $Chobonguon{\lrcorner}$ is that 'Nature-Emotion(性情)' is a action of mind and 'Knowing-Acting(知行)' is a action of body in human. He emphasized that we should try to become saint through controling 'Nature-Emotion(性情)' and 'Knowing-Acting(知行)' 3. It was thought that The span of lift is different according to the volume of Oi(氣) existed in the smallest organ. To manage the Qi(氣) existed in the smallest organ, it is very important to recover 'Good Qi of each constitution(體質正氣)' through cultivating Heart and body. 4. The constitutional viewpoint of human suggested in ${\ulcorner}Dongyi$ Suse Bowon Sasang $Chobonguon{\lrcorner}$ is that Human is classified into four constitutions according to 'Natural Principle of Organ(臟腑性理)' of 'Human Nature(人性)' mind and 'Knowing-Acting(知行)' of 'Human Form(人形)' 5. The viewpoint of human suggested in ${\ulcorner}A$ Aphorism in Teaching Children(敎子平生箴)${\lrcorner}$ emphasized 'Heart('心')'. but The viewpoint of human suggested in ${\ulcorner}Dongyi$ Suse Bowon Sasang $Chobonguon{\lrcorner}$ emphasized' Natural Principle of Organ(臟腑性理)' of 'Human Nature(人性)' mind and 'Knowing-Acting(知行)' of 'Human Form(人形)' and developed the viewpoint of human suggested in ${\ulcorner}Dongyi$ Suse $Bowon{\lrcorner}$.

‘사상체질진단 및 상담’ 부문의 요양급여 확대를 위한 제안

이의주,이준희,고병희 사상체질의학회 2017 사상체질의학회지 Vol.29 No.4

The Sasang Constitutional Examination, which is a medical treatment for Korean medicine, is a insurance non-coverage item. It is necessary to diagnose the constitution for medical treatment and to know the health regimen according to the constitution. We plan this project in order to expand the insurance guarantee reinforcement for Sasang Constitutional Examination and Counselling. This study was to investigate the status of insurance coverage and non-coverage items and to investigate objectivity and standardization of Sasang Constitutional Examination and Counselling. In addition, according to medical field, the items of Sasang Constitutional Examination and Counselling were divided. We reviewed the status of constitutional health care services and applied it to the financial budget for the medical care costs. Finally we propose Sasang Constitutional Examination and Counseling of Korean Medicine Act Classification (plan) and propose Insurance Coverage of Sasang Constitutional Examination and Counselling (plan).

동무공(東武公)의 지행(知行)에 관한 고찰(考察)

이의주,고병희,송일병,임진희,Lee, Eui-Ju,Koh, Byung-Hee,Song, Il-Byung,Lim, Jinny-Hee 사상체질의학회 2002 사상체질의학회지 Vol.14 No.2

1. Objects of Research This research is purposed to find Dong-mu's thought on 'Knowing-Airing(知行), through summarizing sentences related to 'Knowing-Acting(知行)'proposed in his writings. 2. Methods of Research It was researched bibliologically with Dong-mu's chief medical writings such as ${\ulcorner}$Gyukchigo(格致業)${\lrcorner}$, ${\ulcorner}$Dongyi Soose Bowon(東醫壽世保元)${\lrcorner}$ , ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun(東醫壽世保元四象草本卷${\lrcorner}$, ${\ulcorner}$Dong-mu's posthumos work(東武遺葉)${\lrcorner}$. 3. Results and Conclusions 1.'Knowing(知)'is related to recognition of 'Mind(心)' and 'Acting(行)' is related to practice of 'Body(身)' in ${\ulcorner}$Gyukchigo(格致藁)${\lrcorner}$ . 'Knowing-Acting(知行)' in ${\ulcorner}$Gyukchigo(格致藁)${\lrcorner}$ is regard as a important factor to reach the state of 'Golden mean(中庸)' by 'Perception of Man(知人)' 2. 'Knowing-Acting(知行)' in ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun(東醫壽世保元四象草本卷${\lrcorner}$ is thought to recognize and practice marals such as 'Humanity Justice propriety Wisdom(仁義禮智)' and 'Loyality Filialpiety Friendahip Fraternity(忠孝友悌)'. It was proposed that people are classified into Sasang Constition by 'Knowing-Acting(知行)' in ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun(東醫壽世保元四象草本卷${\lrcorner}$ 3. 'Knowing-Acting(知行)' in ${\ulcorner}$Dongyi Soose Bowon(東醫壽世保元四象草本卷)${\lrcorner}$ is difffrent from 'Knowing-Acting(知行)' in ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun(束醫壽世保元圖象草本卷${\lrcorner}$ 'Knowing(知)'is conception of marals such as 'Humanity Jusrire propriety Wisdom(仁義禮智)' and Loyality Filialpiety Friendship Fraternity(忠孝友悌)'. 'Acting(行)' is conception of productivity such as 'Scholar Farm Engineer Merchannt(士農工商)' and 'Field Residence District Nation (田業邦國). 4. 'Knowing-Acting(知行)' in ${\ulcorner}$Dong-mu's posthumos work(東武遺葉)${\ulcorner}$ was c1assified into large and small one. The large one is private and the small one is public. It is imponant to become sincere and respectful for achieve 'Ideal medium of Knowing-Acting.'.

경인지역의 임상검체에서 분리된 이질균의 항생제에 대한 감수성

이의주,정경석 대한임상검사정도관리학회 1985 臨床檢査와 精度管理 Vol.7 No.1

사상인변증(四象人辨證)의 확충(擴充)을 위한 연구(硏究) -[동의수세보원사상초본권(東醫壽世保元四象草本卷) 병변편(病變篇) 제오통(第五統)] 을 중심으로-

이의주,Lee, Eui-Ju 사상체질의학회 2002 사상체질의학회지 Vol.14 No.3

Objectives ; A Supplementary Study for Sasangin Identifing is based on Chapter Pathophysiology Part V of [Donggyi Soose Bowon Chobonguan]. And I try to explain that with Sasang Constitutional Theory. After all I want this study given the basis of 'The Guideline of Sasangin's Diagnosis & Treatment(GSDT)'. Methods ; First, I divid ${\ulcorner}$part V${\lrcorner}$ into 4 cartegories (Normal Condition, Abnormal Condition, good or bad Condition, Better or Worse Condition). And then each symtom is analyzed by Sasang Constitutional Medicine(SCM). Conclusions; I am sure that it gives the first step toward Indentifying Sasangin of [Donggyi Soose Bowon]. All of Sasangin Identifing Supplementary are analyzed by SCM. They are divided the identifing for Sasangin classification and Sasangin diagnosis of the disease. And this study will give the basis of ‘GSDT’.