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      • KCI등재

        양 하지의 근력저하를 주소로 응급실로 내원한 원발성 알도스테로증 1예

        안력,김원,조규종,홍정석,이미우,장성은,오세현,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

        A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranial-spinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5∼ 1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immune-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state. Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus. She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature.

      • SCOPUSKCI등재

        원예치료를 통한 여성재소자들의 사회성 및 대인관계 변화 연구

        김미선,안경선,이진영,이상미,이시래,서정근 한국식물인간환경학회 2000 인간식물환경학회지 Vol.3 No.4

        The purpose of this study was identify change for socialite and interpersonal relationship of female prisoner through horticultural therapy on 14 prisoners in ○○female prison located in Chung-Book. Measurement methods were used Scale of sociality, Scale of change for interpersonal relationship, Form for evaluation of horticultural therapy. The results were as follows; 1.After HTP, Sociality was increased on female prisoners. and there was statistically significant difference(p〈0.01). 2.According to low-ranking field of I-R, communication, sensitivity, openness were increased, satisfaction, confidence, a feeling of intimacy were decreased, understanding was the same after HTP. But the average was increased, and there was statistically significant difference(p〈0.01). 3.Form for evaluation of horticultural therapy showed a increase of participation, interest and assistance, verbal communication, interpersonal relationship. Through above result, horticultural therapy has positive effect far socialite and I-R on female prisoners.

      • 남자대학생의 흡연태도와 행동에 관한 연구

        강경진,김정미,민혜영,안소진,오경숙,은경희,이현,이희선,홍주미,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

        There have been so many researches about problems of cigarettes and relation of smoking and heath since 1950's and generally known that smoking is one of the worst factor of increasing disease and mortality. No matter what such many proofs about various problems of smoking have been researched, smoking rate of current male collage students has not been decreased. Besides, most of the researches about cigarette use and its addiction have been focused on the adolescent or adult women smokers or adult male, not male collage student. Therefore, the subject of this study is about smoking attitude and smoking behavior of male collage students by general features. Smoking attitude was analyzed by modifying 'Guidelines for the content of tobacco smoking surveys of the general population'(WHO, 1982). Two hundred of male collage students participated to the distributed questionnaire for one week in May. The smoking attitude was categorized into duration of smoking and number of cigarette per day(CPD), and nicotine dependency, investigated by Fagerstrom Tolerance Questionnaire(FTQ) (Fagerstorm & Schneider, 1989). All statistics were performed by procedure of SAS according to number, percentage, mean, standard deviation, and ANOVA. The results are as follows: 1. Smoking attitude level was mean 25.73±5.15 marks, ranging from 13 to 39 marks of the total 40 marks. 2. Duration of cigarettes, number of cigarette per day, and nicotine dependency were mean 5.14±2.84 years, 12.88±6.85 pieces, and 4.78±1.69, respectively. 3. Smoking attitude showed significance according to general features such as marital state and allowance, but the significance according to marital state is not valuable because the numerical difference is so big between married one and single that they cannot be compared with each other. 4. Duration of smoking was significant according to general features such as age and allowance. 5. Smoking amount showed significance the factors of age only. 6. ll1ere was no significance in nicotine dependency according to general features. As a result, smoking attitude of male collage student in this study shows moderate level. Smoking attitude and duration is significant according to allowance, and smoking amount is significant according to age. Nicotine dependency according to general features is not significant but comparing with the preceding study about adult male, male collage students in this study are respectively more nicotine-dependent than adult male smokers. In conclusion, the right allowance usage strategies and effective heath education focused on the young are needed. In addition, helpful programs and information spreading strategies are necessary for establishing higher level of smoking attitude. At last, systemic regulations in daily living for ""anti-nico-dependent"" and perspective reforming of male university student are needed for reducing nicotine dependency.

      • 중·장년층의 스트레스 완화를 위한 뇌호흡 프로그램 적용 효과

        심준영,오미경,안승찬,이승헌 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.4

        This study assigns 21 subjects randomly who had no brain respiration training and regular exercise experience to 7 subjects with brain respiration training, 7 subjects with aerobic exercise experience and 7 subjects of control group in order to examine their physiological reactions of stress when brain respiration program was applied to the middle-aged class in their thirties and forties, and the experiment was conducted for one hour per session by three times a week for 8 weeks. After eight-week experiment, it measured ACTH, Cortisol, heart rate(HR), skin conductance level(SCL) and breath rate(BR) before and after stimulus when they were exposed to auditory noise and mental arithmetic stressor and analyzed results. ACTH and Cortisol showed little change or reduction in brain respiration group before and after stimulus, compared to the increase of ACTH and Cortisol in aerobic exercise group and control group, but there was significantly significant trend in HR, SCL and BR. In particular, in ACTH density, brain respiration group showed a significant change between group and period and it is found that application of brain respiration program is effective in reducing vigorous maintenance of homeostasis of temporary stimulus and reaction against stress.

      • KCI등재

        자궁근종 환자에서 정맥과 우심방 혈전의 방사선학적 소견을 보인 정맥내 평활근종 1예

        김제상,강미라,이상철,박표원,김병기,안긍환,장경식 대한내과학회 2004 대한내과학회지 Vol.66 No.5

        저자는 과거 자궁근중으로 수술한 50세 여자 환자가 심부전 및 광범위한 혈전증의증으로 본원에 내원하여 수술후 정맥내 평활근종으로 밝혀진 증례를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. A case of intravenous leiomyomatosis (IVL) invading the vena cava and extending to the right atrium, a rare benign smooth-muscle tumor, is described. Despite their histological benignity these lesions have a tendency to metastasize and are closely related to the condition called "benign metastasizing leiomyoma" and " intracaval mass and cardiac extension" a 50-year old woman was admitted to the hospital with dyspnea beginning 6 months ago and precious history of hysterectomy due to uterne myoma. Echocardiography revealed severe tricupid valve insufficiency and a mobile elongated mass which occupied the inferior vena cava and was extending into the right ventricular cavity. Pelvic ultrasonography and pelvic MRI identified suspicious metastasis to both ovaries and peritoneum. She underwent resection of the cardiac tumor, conomitant tricuspid annuloplasty with a closure of the foramen ovale and both salphyngo-oophorectomy with vaginal stump mass biopsy. All of them could be histologically identified as IVL.

      • KCI등재

        경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

        홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

        Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

      • KCI등재
      • KCI등재

        혈관내피세포 손상과 에스트로겐, 프로게스테론 관계에 대한 연구

        김미경 ( Mi Kyoung Kim ),김지애 ( Ji Ae Kim ),전여진 ( Yeo Jin Jeon ),박종순 ( Jong Soon Park ),박미혜 ( Mi Hye Park ),서석효 ( Suk Hyo Suh ),전선희 ( Sun Hee Chun ),안정자 ( Jung Ja Ahn ),김영주 ( Young Ju Kim ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.3

        목적: 자간전증 산모에서 에스트라디올, 에스트리올, 프로게스테론 농도 변화를 규명하고 LPC에 의한 세포 독성에 미치는 에스트로겐과 프로게스테론의 효과를 규명하고자 하였다. 연구방법: 자간전증 산모와 정상 산모를 대상으로 혈중 에스트라디올, 에스트리올, 프로게스테론, 산화성 저밀도지질단백 농도를 측정하였으며, LPC를 인간제대정맥 내피세포에 처리한 후 에스트로겐, 프로게스테론을 여러 용량으로 주었을 때 세포독성 억제 여부를 알아보았다. 결과: 에스트라디올, 에스트리올 혈중 농도는 자간전증 환자에서 정상 산모에 비해 감소하였고 산화성저밀도 지단백의 농도는 증가하였다 (P<0.05). 인간제대정맥 내피세포에 LPC를 첨가하였을 때 농도 의존적으로 세포 독성을 증가시켰으며 에스트로겐과 프로게스테론의 첨가는 각각 용량 의존적으로 세포 독성을 감소시켰다 (P<0.05). 결론: 자간전증에서의 에스트로겐, 프로게스테론 농도 감소는 자간전증의 내피세포 손상과 연관이 있으며 에스트로겐, 프로게스테론은 자간전증의 예방과 치료에 있어서 중요한 역할을 할 수 있을 것으로 생각되어 이에 대한 계속적인 연구가 필요하다 하겠다. Objective: The aim of this study were to examine the serum level of estradiol, estriol, progesterone, oxidized LDL in preeclamtic patients and to evaluate the protective effects of estrogen and progesterone against lysophosphatidylcholine (LPC) induced cell death in Human umbilical vein endothelial cells (HUVECs). Methods: We analysed the serum level of estradiol, estriol, progesterone, oxidized LDL in patients with preeclampsia and control. We used LPC to induce cell death in HUVECs. For cytotoxic assay, we did LDL assay for cell death and Resazurin assay for cell viability. HUVECs were exposed to various concentrations of LPC, LPC+estrogen, LPC+progesterone and we did cytotoxic assay. Results: The serum estradiol, estriol were lower in the preeclamptic patients (P<0.05). Oxidized LDL were higher in the preeclamptic patients(P<0.05). LPC induced cell death in a concentration-dependant manner. Estrogen or progesterone inhibited LPC-induced cell death in a concentration-dependant manner (P<0.05). Conclusion: Estrogen and progesterone attenuated LPC-induced cytotoxicity. The results suggest that Oxidized LDL induced endothelial damage in preeclampsia may be induced by low serum estradiol, estriol and progesterone levels and prevented by estrogen and progesterone addition.

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