멜라민 수지 조리기구 중 formaldehyde 및 phenol의 이행에 관한 연구

오재명,안미경,김진철,신동우,박창원,김미혜 한국식품위생안전성학회 2014 한국식품위생안전성학회지 Vol.29 No.1

Formaldehyde and phenol used in the production of melamine-wares may be intended to come intofoodstuffs. So this study investigated the migration of formaldehyde and phenol from 222 articles Articles werecups(14), bowls(75), plates(85), spoons(10), chopsticks(4), food trays(8), rice paddles(4), spatulas(9) and scoops(12). The food stimulants were 4% acetic acid, 20% ethanol, distilled water and n-heptane. Korea regulation (Standards andspecifications for food utensils, containers and package) specifies migration limits for formaldehyde and phenol infood stimulants. Formaldehyde and phenol are restricted by 4 mg/L, 5 mg/L respectively. In all cases the migration offormaldehyde and phenol were below the limit set in Korea regulation. The level of formaldehyde and phenolmigrated to food simulants were in the range of N.D~2.949 mg/L, N.D~0.078 mg/L respectively. These migrationresults of formaldehyde and phenol will provide a scientific basis for the safety management of melamine-wares.

멜라민 수지 조리기구 중 formaldehyde 및 phenol의 이행에 관한 연구

오재명,안미경,김진철,신동우,박창원,김미혜 한국식품위생안전성학회 2014 한국식품위생안전성학회지 Vol.29 No.3

멜라민수지 조리기구 제조에 사용되는 formaldehyde와 phenol의 경우 식품에 이행될 우려가 있다. 이에 본 연구에서는 국내에서 유통되고 있는 멜라민수지 조리기구 222 건에 대하여 formaldehyde와 phenol의 식품유사용매로의 이행량을 조사하였다. 멜라민수지 조리기구는 컵(14), 공기(75), 접시(85), 숟가락(10), 젓가락(4), 식판(8), 주걱(4), 뒤지게(9) 및 국자(12)등을 수거하였다. 식품유사용매로는 물, 4% 초산, 20% 에탄올, n-헵탄을 사용하였다. 한국의 멜라민수지 기구 및 용기·포장 중 formaldehyde와 phenol의 용출기준은 각각 4 mg/L, 5 mg/L 이며, 수거된 222건 멜라 민수지 조리기구 모두 기준·규격에 적합하였다. 멜라민 수지 조리기구 중 formaldehyde와 phenol의 이행량은 각각 N.D~2,949 μg/L, N.D~78 μg/L이었다. 위 분석결과는 멜라민수지 기구 및 용기·포장의 안전관리의 과학적 근거 자료로 제공될 수 있을 것으로 판단된다. Formaldehyde and phenol used in the production of melamine-wares may be intended to come into foodstuffs. So this study investigated the migration of formaldehyde and phenol from 222 articles Articles were cups(14), bowls(75), plates(85), spoons(10), chopsticks(4), food trays(8), rice paddles(4), spatulas(9) and scoops(12). The food stimulants were 4% acetic acid, 20% ethanol, distilled water and n-heptane. Korea regulation (Standards and specifications for food utensils, containers and package) specifies migration limits for formaldehyde and phenol in food stimulants. Formaldehyde and phenol are restricted by 4 mg/L, 5 mg/L respectively. In all cases the migration of formaldehyde and phenol were below the limit set in Korea regulation. The level of formaldehyde and phenol migrated to food simulants were in the range of N.D~2.949 mg/L, N.D~0.078 mg/L respectively. These migration results of formaldehyde and phenol will provide a scientific basis for the safety management of melamine-wares.

건강기능식품 프랑스해안송껍질추출물 중 UPLC-MS/MS를 이용한 Ferulic acid, Caffeic acid, Catechin, Taxifolin 동시분석법 개발 연구

오재명,김지안,허수정,최윤희,오금순 한국식품위생안전성학회 2019 한국식품위생안전성학회지 Vol.34 No.5

This study was conducted to develop a simultaneous analysis method for ferulic acid, caffeic acid, catechin and taxifolin from Health Functional Food (HFF) Pinus Pinaster bark extract. The simultaneous analytical method for ferulic acid, caffeic acid, catechin and taxifolin is carried out using UPLC-MS/MS. The method validation was performed to determine selectivity, linearity, accuracy, limit of detection (LOD), limit of quantification (LOQ) and precision for ferulic acid, caffeic acid, catechin and taxifolin. LC-MS/MS method was established using an Acquity UPLC BEH C 18 Column and was applied for these 4 compounds. Product-ion traces, at m/z 194.2 → 133, 180.2 → 135, 290.3 → 245, 304.3 → 248, were used for quantitative analysis of ferulic acid, caffeic acid, catechin and taxifolin, respectively. Excellent linearity (r 2 =0.999) was observed for ferulic acid, caffeic acid, catechin and taxifolin in the concentration range (50-2500 mg/L). The observed recoveries of these 4 compounds were found to be between 84.9 and 104.9%, while precision was between 1.20 and 4.43% relative standard deviation (% RSD).

Rosa canina L. 중 hyperoside의 시험법 개발 연구

오재명,이화정,반경녀,서일원,이영주,이진희,박지민,강태석 한국식품위생안전성학회 2015 한국식품위생안전성학회지 Vol.30 No.2

Rosa canina L. is health functional food materials that can help to temporarily relieve symptoms of arthritis. This study has been conducted to develop and validate analytical methods for hyperoside of Rosa canina L.. Methods based on HPLC with ultraviolet detection(UVD) were established through instrumental analytical conditions, and the examination of data, such as domestic and foreign reliable methods and journals. HPLC UVD analysis using Capcell Pak C18 MG II column at 353 nm was determined on test through the column, mobile phase. The validation has been performed on the method to determine linearity, accuracy, limits of quantification (LOQ) and repeatability for hyperoside. The method showed high linearity in the calibration curve at a coefficient of correlation(R2) of 0.999, and the LOQ was 0.393 ㎍/mL. Relative standard deviation(RSD) values of data from repeatability precision was between 0.6 and 2.6%. Recovery rate test at hyperoside scored between 98 and 99 %. These results indicate that the established HPLC method is very useful for the determination of hyperoside in Rosa canina L. to develop a health functional material.

2차원 층상구조를 갖는 소결조제와 이를 활용한 세륨산화물 소결성 향상

박지영,오재명,박희정 한국결정성장학회 2019 韓國結晶成長學會誌 Vol.29 No.1

The physical properties of ceramic materials including oxides are greatly influenced by the material density. Therefore, various efforts have been made to increase the material density. One of the most popular strategies is to use sintering additives in sintering materials. The conventional sintering additive was a spherical powder having a threedimensional structure. In this study, sintering additive with 2-dimensional (2D) layer structure was used to increase the sintering density of cerium oxide and its effect was confirmed. In this study, 1 nm-thick TiOx and MnOx nanosheets were used as sintering additives. 산화물을 포함한 세라믹 재료의 물성은 소재 치밀도에 크게 영향을 받는다. 따라서 소재 치밀도를 높이기 위한다양한 노력들이 진행되어왔다. 이중 많이 사용되는 전략으로 재료 소결 시 소결조제를 첨가하는 것이다. 기존의 소결조제는 3차원 구조를 갖는 구형의 분말이었다. 본 연구에서는 차별화 전략으로 세륨산화물의 소결 밀도를 높이기 위해 2차원층상구조를 갖는 소결조제를 첨가하였다. 실제로 2차원 층상구조의 조결조제에 의해 소결밀도가 증가되는 것을 확인할 수있었다. 2차원 층상구조 소재로 초나노 두께(~1 nm)를 갖는 TiOx와 MnOx 나노쉬트가 이용되었다.

유전자재조합 식품의 알레르기성 평가

박선희,구용의,오재명 대한천식알레르기학회 2008 천식 및 알레르기 Vol.28 No.1

Poly (ethylene naphthalate) (PEN 수지)의 2,6-디메틸나프탈렌 디카복실레이트 (2,6-NDC)과 2,6-나프탈렌디카복실산(2,6-NDA) 분석법 확립

김미혜,성준현,오재명,신동우,최재천,임호수,박세종,박건우,김소희 한국식품위생안전성학회 2013 한국식품위생안전성학회지 Vol.28 No.1

Poly (ethylene naphthalate) (PEN), which is likely to be widely used in various application due to good barrier properties, is manufactured by condensation polymerization of 2,6-dimethylnaphthalene dicarboxylate (2,6-NDC) or 2,6-naphthalene dicarboxylic acid (2,6-NDA) with ethylene glycol. In this study, an analytical method to determine monomers in food simulants, which might migrate from PEN food contact materials into food, was developed. The HPLC-UV method was validated for 2,6-NDC and 2,6-NDA. The obtained validation parameters were selectivity, sensitivity, linearity, precision and recovery. The simultaneous HPLC method was considered the be most effective analytical method to determine 2,6-NDC and 2,6-NDA in food simulants. 본 연구에서는 PEN 수지 안전관리를 위하여 HPLC-UV검출기를 이용한 2,6-NDC 및 2,6-NDA 분석법을 확립하였다. 분석법 검증 결과, 2,6-NDC 및 2,6-NDA 모두 0.002μg/mL 검출한계, 0.005 μg/mL 정량한계 및 0.05~1 μg/mL의 농도 범위에서 r2= 0.999 이상의 직선성을 확인할 수있었다. 또한 회수율도 90~110%임을 확인할 수 있었다.

유전자재조합 식품의 알레르기성 평가

박선희,구용의,오재명 대한알레르기학회 2008 천식 및 알레르기 Vol. No.

데오도라이트 시스템의 측정 불확도 연구

이건탁,이동주,윤용식,박홍철,오재명 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

Theodolite measurement system is non-contacted 3-dimensional measurement system. The system accuracy is 0.5 mm or better for distance 0 ~ 100m. And the system is used for a product of middle and large scale. This study is performed for the measurement uncertainty of the system. We could know that the main uncertainty factors are temperature, illumination and skill. And, we perform the study for the effect according to the height difference of scale bar. And, we calculated the measurement uncertainty with those factors.

건강기능식품 등 중 수용성 비타민 B군의 HPLC를 이용한 동시분석법

김선희,김재현,이화정,오재명,이성혜,반경녀,서일원,이영주,이진희,강태석 한국식품위생안전성학회 2015 한국식품위생안전성학회지 Vol.30 No.2

This study was conducted to simultaneous analysis methods for water soluble vitamins B group (vitamin B1, vitamin B2, nicotinic acid, nicotinamide, vitamin B6) which is used as health functional foods etc. Analytical methods of water-soluble vitamins B group by HPLC were established through instrumental analytical conditions, and the examination of data such as domestic and foreign reliable methods, and papers of journal. HPLC method analyzing water soluble vitamins B group was established using Capcell Pak C18 UG 120 column in 270 nm through test of columns. The validation has been performed on the method to determine linearity, accuracy, limits of quantification (LOQ) and repeatability for water soluble vitamins B group. An excellent linearity (r2=0.999) was observed for vitamin B1, vitamin B2, nicotinic acid, nicotinamide, vitamin B6 in the concentration range (0.1∼2 μg/mL). Observed recovery of vitamin B1 was found to be between 100 and 103%, vitamin B2 was found to be between 104 and 112%, nicotinic acid was found to be between 82 and 85%, nicotinamide was found to be between 121 and 124% and vitamin B6 was found to be between 95 and 104%. LOQ of vitamin B1 was found to be 0.04 μg/mL, vitamin B2 was found to be 0.05 μg/mL, nicotinic acid was found to be 0.15 μg/mL, nicotinamide was found to be 0.08 μg/mL and vitamin B6 was found to be 0.63 μg/mL. Repeatability precision for vitamin B1 was found to be 0.4%, vitamin B2 was found to be 0.4%, nicotinic acid was found to be 0.5%, nicotinamide was found to be 0.7% and vitamin B6 was found to be 0.4% relative standard deviation (RSD). Also, verify the accuracy of the simultaneous analysis methods, we monitored the labeled contents of the health functional foods and children's preferred foods.