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황창환(Chang Hwan Hwang),백승욱(Seung Wook Baek),한조영(Cho Young Han),김수겸(Su Kyum Kim),전형열(Hyung Yeol Jeon) 한국연소학회 2012 KOSCOSYMPOSIUM논문집 Vol.- No.45
The droplet behavior of 83.9 wt.% HAN water solution was investigated experimentally with various ambient temperature and nitrogen environment. At the initial stage of evaporation under thermal decomposition temperature of HAN, gradual decreasing of droplet diameter was observed. After that, the droplet started to expand due to the internal pressure build up by water nucleation inside the droplet. The micro explosion was observed at higher temperature than the decomposition temperature of HAN and the remaining droplet showed similar behavior of single composition droplet. The decreasing rate was augmented as the ambient temperature increasing.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
한국인 Fragile-X 증후군 환자의 분자 유전학적 진단
김경모,유한욱 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.2
Fragile-X syndrome (FXS) is the most common cause of inherited mental retardation. Until recently, the diagnosis of FXS has been made based on the cytogenetic expression of the fragile site at Xq27.3 (FRAXA) in the patients' cultured cells and on the results of linkage analysis with DNA markers surrounding the fragile X locus. The recent cloning of fragile-X gene(FMR-1) made it possible investigate the molecular defects in FMR-1 gene of individuals at risk. Vast majority of molecular defects of FXS has been known to be an abnormally amplified trinucleotide(cytosine guanine guanine) repeat. This study aims at establishing the molecular genetic diagnosis of FXS as well as correlating genotype-phenotype analyzing the increment of amplified CGG repeat number, clinical findings, and cytogenetic expression rate in two Korean families with FXS patients. The FXS patients are tested cytogenetically & molecular genetically. The fragile site at Xq27.3 was cytogenetically expressed in folate deficient medium by culturing lymphocytes for 4 days. Molecular diagnostic approaches utilize the genomic DNA Southern blot analysis using genomic probe FXA 241 (ONCOR) and radiolabelled PCR-denaturing polyacrylamide gelelcetrophoresis. Each patient expressed a FRAXA site in folate deficient medium with the expression rate of 38%, 16% respectively. The molecular genetic study showed that each patient had the CGG amplification 1.6kb, 0.7-0.8kb in the FMR-1 gene respectively. In addition, this study clarified the carrier status of each family members. In conclusion, molecular genetic studies employed in this study can be utilized for a confimatory diagnostic purpose in FXS patients.
ISP의 BcN 투자 및 요금체계 평가모형 : 실물옵션과 몬테카를로 시뮬레이션의 응용
김도훈,정한욱,방정희,박명선 한국정보사회진흥원 2006 정보화정책 Vol.13 No.3
모든 정보통신서비스가 All-IP 통합 인프라로 제공되는 BcN 구축은 우리나라의 핵심 국책사업 중의 하나로, 인터넷 강국으로서의 글로벌 입지를 굳히는데 결정적인 역할을 할 것으로 기대된다. 그러나 BcN 기술의 성숙에도 불구하고, 제도적 측면에서 이의 성공을 뒷받침하는 연구는 드물다. 특히 BcN 요금체계와 같은 정책적 문제에 대해서는 별다른 진전이 없다. 본 연구에서는 요금정책이 BcN 투자에 미치는 영향을, 실물옵션과 Monte Carlo 시뮬레이션을 이용하여 분석하였다. 실험결과, BcN 수요의 불확실성뿐만 아니라, 요금체계와 관련된 정책대안이 사업자의 수익구조와 투자동기에 중요하게 작용하였다. 또한 수익과 투자시점은 밀접한 관계를 가지며, 트래픽 규모가 수입에 직접 반영되는 요금체계에서 BcN 투자가 앞당겨짐을 알수 있다. 특히 ISP와 CP간의 요금체계가 투자 의사결정에 보다 크게 작용하는 것으로 파악된다. 이러한 결과는, 사업자의 자발적인 첨단 인프라 및 서비스 개발이 국민경제에 긍정적으로 작용하는 동태적 효과를 보다 전향적으로 검토할 것을 요청한다.
한강시민공원 체육시설 현황과 효율적 활용 방안에 대한 연구
한진욱,김진호 경희대학교 체육과학연구소 1999 體育學論文集 Vol.27 No.-
The aim of this study is primarily to examine the current state of the sports facilities for the Han-Gang Citizens' Park and to propose its effective utilization plans for the coming 21st century. The main findings and conclusions can be described as follows: 1.Strengthening of publicity fucntions 2.To provide citizens with various means of easy access to the Park such as shuttle buses and samaul buses 3.Developments of new programs for the disabled and senior citizens 4.Extensive utlization measures for the evening hours 5.To make the Park distictive according to each distict 6.Reorganization of the Parks' administrative structures 7.Diversification of programs, and training and retaining instructors of an excellent caliber.
한국인 집단에서 미토콘드리아 DNA의 'Asian-specific 9-bp결실'다형현상
김욱,진한준 단국대학교 1999 論文集 Vol.34 No.-
Length changes in mitochondrial DNA (mtDNA) offer a useful marker for the study of female aspects of human population history. One such length change is the intergenic COⅡ/tRNA^Lys 9-bp deletion, which the region usually contains two tandemly arranged copies of a 9-bp sequence (ccccctcta) in human mtDNA. This deletion has been reported at varying frequencies in populations from Asia. Polynesia, the New World, and sub-Saharan Africa. This genetic polymorphism of mtDNA was analyzed in samples from 171 unrelated individuals from the Korean population and compared the frequency and distribution of 9-bp deletion with other Asian population. The frequency of the 9-bp deletion was found to be 17.5% (30/171) in the Korean populations. Uncommonly, a new insertion allele of approximately 6-bp in the intergenic COⅡ/tRNA^Lys region in the Korean population (2/171) was first identified in this study. East Asian populations including Chinese. Japanese, and Koreans were relatively homogeneous in the frequency of 9-bp deletion. with the exception of the low frequency of this deletion in Mongolians. On the other hand, Indonesians and Malaysians of Southeast Asian populations were found to show relatively high frequencies of the 9-bp deletion. Based on results of the frequencies of the 9-bp deletion, the Japanese population appeared to have a closer genetic relationship to Koreans than to the other surveyed Asian populations. Therefore, the results of this study also supported the hypothesis that a large amount of the gene pool in mainland Japanese was derived from the continental gene flow after the Yayoi Age.