도장작업시 유해인자들의 노출수준과 작업환경관리실태

이세기,문덕환,이채관,황용식,선병관,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objectives: For the purpose of preparing the fundamental data and assessing the status of exposure level of chemical substances in painting process. Methods and Materials: The author determined the concentration of organic solvents, lead(Pb), Chromium(Cr), and Toluene-2, 4-diisocyanate(TDI) in air of painting process to 90 industries classified by 15 types of manufacturing industry during a period from Jan. 1st 2001 to Dec. 31st 2001. Results: The results were as follows: 1. The geometric mean level of each chemical substance was 0.1706 ppm for exposure index in organic solvents, 0.0019㎎/㎥ for Pb, 0.0024 ㎎/㎥ for Cr, and 0.0004ppm for TDI, respectively. 2. The exposure level of each chemical substances by type of painting was the highest in dipping and brush painting for organic solvent, in spray-painting for TDI, and in spray gun-painting for Pb and Cr, respectively. 3. The exposure level of each chemical substances by type of local ventilation equipment was higher in enclosed and booth type for organic solvents. Cr, and TDI, and in exterior type for Pb, respectively than those of other types. 4. The exposure level of each chemical substances by type of hazardous material arresting media was higher in using water for organic substances, in using bag filter for Pb, TDI, respectively than those of other types. Conclusion: According to above results, this study suggests that the exposure level by type of industry exceeded the exposure level in wooden furniture and metal furniture manufacturing industry for organic solvents and Pb, respectively.

한랭작업 근로자들의 건강위해에 관한 연구

박호추,정설미,문덕환,이종태,김대환,김정호,최재일,황용식,이용희,이채언 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.1

In order to evaluate the status of cold exposure and its health hazards of workers at cold storage workplaces and to provide basic data for effective health care, the author measured core temperature and also observed clinical symptoms and signs, past and present history, and general health examination data on 99 cold exposed workers for exposure group and 96 non-exposed workers for control group working at 2 food refrigerating companies in Pusan area from January 6, 1998 to February 24, 1998. The results were as follows: 1. There was statistically significant difference in water intake between the exposure and control group and increased urine volume, urine frequency in exposure group without statistically significant difference. 2. Past and present illness in exposure group were hypertension (18.2%), hepatopathy (8.1%), gastro-intestinal disease(7.1%), arthritis (4.0%), intervertebral disc herniation(4.0%), and so on, and hypertension, arthritis was statistically significant difference compared to control group. 3. Symptoms in exposure group were fatigue(89.9%), headache (64.6%). drowsy(63.6%), neck stiffness(59.6%), excessive food intake(59.6%). general weakness(58.6%), hunger(58.6%), numbness(54.5%), and so on, and there was statistically significant difference between the exposure and control group except fatigue, drowsy. 4. As results of clinical test abnormality rate of the systolic, diastolic blood pressure and electrocardiogram were significantly higher in exposed group than control. 5. Core temperature in exposure group was statistically significantly lower than control group and the highest statistically significant inverse correlation with the working hours and working frequency of daily mean cold storage. As above results, the author suggested that the further studies should be conducted to evaluate the health status of workers about chronic health effects in cold workplaces and to establish effective health care methods for them.

혈청 및 뇨 amylase 측정치의 임상적 검토

이기환,구광호,이상용,이규용,유언호,김종숙 ( Ki Whan Lee,Kwang Hoo Koo,Sang Yong Lee,Kyu Yong Lee,Un Ho Ryoo,Chong Sook Kim ) 대한소화기학회 1974 대한소화기학회지 Vol.6 No.1

The measurements of sium amylase and urine amylase for 2-1 and 2 hrs were caried ou normal perso,-s, 118 pat;:enls vith disardei s in the upp r alimentary tract, 184 patie.,ts v, ith h;le- cystopathy and 26 patients ivith acute pancreatitis. The follosving rc.su1ts were drawn: In the normal prsons, the average determination of serum amylas was 5-l. I L 21, 9. Units ' 100 m]. It shov;ed no difference by sex and age. 2 The frequezcy manifesting raise of serum amylase (the value higher than mean+2S.I),,, v,as 5 ] y in the patients with the upper G.I. Disorders, an<l 6, l,jj in the patients of chiIccys'.:>p.ithy v, ith normal features in cholecys.ograms. It, however, showed 2S. 7, of frequeny appeaiing nis:.. of serv,m an.ylase in the patients of cholecystopathy with abnorrnalities in roentgenographic exa!ii- ;iations indicating a mean value of 86. 4 31. 67 units,'l0(l ml. 3, The determination of s rum amylase in the pat,ents of acute pancreatitis was 12a. ] un!ts,'100 ml on the initial day, and it showed ahrupt diminution thereafter. 4. Each dete:mination of urine amylase for 24 and 2 hnurs was 1394. 3 .867. 43 and 15 4 -(j;, Hi units in the normal pers1ns, but there was no significant shift in the group of the uppr:.;- G,I disorders, and a little raise in the group of cholecystopathy. In the group of acute panc:eatili:., ii showed marked rais of urine amylas, ,6562, 9---4526, 3<J units for 24 hours on the se ond cia o!' ailment), revealins: subs quent gradual cle rease, (30i;>. 9 l 1927. 92 units on the sexth day',. It must b emphasized that in picture of urine amylase should be a great help for c!iagnos!.ng tli. Conditions.

전라북도 남원시 열대의 산림조류상

이두표,신용운 호남대학교산업기술연구소 2009 산업기술연구논문집 Vol.15 No.-

본 연구는 전라북도 남원시 일대의 산림조류상을 파악하기 위하여 2008년 3월부터 10월까지 조류센서스를 실시하고, 그 결과를 분석 평가한 것이다. 총 75종 이 기록되었으며, 그 중 텃새가 29종, 여름철새가 23종, 겨울철새가 17종, 나그네새가 6종으로 나타났다. 이 지역의 우점종은 붉은머리오목눈이, 참새, 되새, 멧비둘기, 노랑턱멧새, 물까치 등으로 나타났다. 법정보호종은 환경부지정 멸종위기 Ⅱ급 인 참매, 말똥가리, 새흘리기, 흰목물떼새로 4종, 문화재청 지정 천연기념물은 원앙, 붉은배새매, 새매, 참매, 황조롱이, 솔부영이로 6종, 총9종이 관찰되었다. Bird censuses were conducted to elucidate the present forest avifauna of Namwon city from March to October, 2006. A total of 75 bird species was recorded. They consisted of 29 species of residents, 23 species of summer visitors,17 species of winter visitors, and 6 species of passage migrants. Dominant species were Paradoxornis webbianus, Passer montaus, Fringilla montifringilla, Streptopelia orientalis, Embenza elegans, Cyanopica cyana. The legal protected birds listed by Ministry of Environment were 4 species: Accipiter gentilis, Buteo buteo Falco subbuteo, Charadrius placidus, and listed by Cultural Heritage Administration were 6 species: Aix galericulata. Accioiter soloensis. A. nisus. A. gentilis. Falco tinnunculus. Ninox scutulata

Hepatoma cell에 증식억제작용을 나타내는 식물들

이은주,정용자 慶星大學校 1998 論文集 Vol.19 No.1

We have studied that the effect on the inhibition of the cancer cell growth by the 3-[4,5-Dime wthylthiazol-2 yl]-2,5-diphenyl-tetrazolium bromide(MTT) assay, to investigate the anticancer effect with plants, observed around us, by culturing the human hepatoma cell-line. And we knew it was the best condition that the cell number was 4×10³ cells/well and the time of culture is 48 hours. We found that Equisetum arvense L. and Lactuca dentata Makino. var. Flaviflora Makino. exhibited a good anticancer effect and especially Capsicum annum L. angulosum Mill exhibited the best effect of them.

흑두로 제조한 청국에서 분리된 Bacillus subtillus BB-1으로부터 혈전용해효소 유전자 크로닝 및 특성규명

이영훈,이성호,전주미,김홍출,조용운,박기훈,최영주,갈상완 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

A bacterium producing five fibrinolytic isozymes was isolated from black bean chung kuk. The bacterium was identified as Bacillus subtilis BB-1 by 16s rDNA sequence homology search. A gene out of five fibrinolytic genes in the Bacillus subtilis BB-1 was cloned by shot-gun method. A Cla ⅠDNA fragment of B. subtilis BB-1 chromosome was cloned in to pBluescript ⅡSK(-) and showed the fibrinolytic activity to bacterial cells. The Cla ⅠDNA fragment was sequenced and the sequences did not show homology with gene for protease or fibrinolytic enzyme genes in other organisms. The Cla ⅠDNA fragment was reduced to 2,142 bp by activity-guided PCR cloning method. The optimum pH and temperature of the enzyme were 5.0 and 35℃, respectively. Substrate specificity of the fibrinolytic enzyme was detected in skim milk, casein, gelatin and blood agar plates. The activity of the enzyme was not detected with these substrates. Taken together, this enzyme is a new fibrinolytic enzyme and may be used to prevent thrombosis and arteriosclerosis.

Rhizopus japonicus와 Zymomonas mobilis의 혼합 고정화 배양계를 이용한 생전분으로부터 비살균처리에 의한 에탄올 발효

이상원,조용운 진주산업대학교 1998 論文集 Vol.37 No.-

Rbizopus japonicus와 Zymomonas mobilis로 구성된 혼합고정화 배양계(R-Z 24계)의 특성을 이용하여 biomass로부터 유용물질 생산을 행할 때 투입되는 에너지를 절약할 목적으로 비가열살균 배양을 검토하였다. R-Z 24계 만으로의 비가열살균 배양은 배지에 함유된 세균 때문에 어려웠다. Sorbic acid, benzoic acid, dehydroacetic acid, P-hydroxybenzoic acid와 Vantocil IB등의 여러 가지 살균제 중에서 0.1% Vantocil IB가 잡균의 생육을 억제하는데 가장 적합하였다. Vantocil IB는 곰팡이보다 세균에 대하여, 또 고정화 배양보다 액체배양에서 더 강한 효과를 나타내었다. 0.1% Vantocil IB를 첨가한 비가열살균 배양에서 2, 5 및 10%의 생전분 기질로부터 각각 6.5g/ℓ(Yp/s=0.38), 14.5g/ℓ(Yp/s=0.36) 및 28g/ℓ(Yp/s=0.33)의 에탄올이 생산되어 살균제를 첨가하지 않은 대조구와 동등한 수율을 얻었다. In order to reduce energy input in direct ethanol production from raw starch without sterilization, (co-immobilized mixed Rbizopus japonicus and Zymomonas mobilis culture system(R-Z 24) which changed to anaeoric from aerobic condition after 24hrs of fermentation was investigated.) R-Z 24 system can not be used for ethanol production because of growth of microbial contaminants from medium under nonstrile condition. 0.1% Vantocil IB was the most effective food additive to suppress the growth of contaminants among sorbic acid, benzoic acid, dehydroacetic acid and p-hydroxybenzoic acid. Microbial growth inhibition of vantocil IB was more effective in a bacteria than in a mold, and also in free culture system than immobilized culture system. By adding 0.1% Vantocil IB to the fermentation medium without sterilization, ethanol production was 6.2g/ℓ (Yp/s=0.35), 14.5g/ℓ (Yp/s=0.36) and 28g/ℓ(Yp/s=0.31) from 2, 5, 10% untreated raw starch respectively. These productivities were similar to those of control culture system without Vantocil IB.

광주광역시 어등산의 산림조류상

이두표,신용운 호남대학교산업기술연구소 2008 산업기술연구논문집 Vol.14 No.-

본 연구는 광주광역시에 위치한 어등산 일대의 산림조류상을 파악하기 위하여 2006년 2월부터 11윌 까지 조류센서스를 실시하고, 그 결과를 분석 평가한 것이다. 총 68종 이 기록되었으며, 그 중 여름철새가 27종, 텃새가 26종, 겨울철새가 11종, 나그네새가 4종으로 나타났다. 이 지역의 우점종은 붉은머리오목눈이, 노랑턱멧새, 박새, 불까치, 쑥새, 직박구리, 참새 등으로 나타났다. 법정보호종은 환경부지정 멸종위기 H 급 인 참매 말똥가리 흰목물떼새로 3종 문화재청 지정 천연기념물은 붉은배새매, 새매, 참매, 황조롱이, 소쩍새, 솔부영이로 6종, 총8종이 관찰되었다. Bird censuses were conduct to elucidate the present forest avifauna of Mt. Eodeung from February to November, 2006. A total of 68 bird species was recorded. They were consisted of 27 species of summer visitors, 26 species of residents, 11 species of winter visitors, and 4species of passage migrants. Dominant species were Paradoxomis webb띠nus, Emberiza elegans, Parus major, Cyanopica cyana, Emberiza rustica, Hypsipetes amaurotis, Passer montanus. The legal protected birds listed by Ministry of Environment were 3 species: Accipiter gentilis, Buteo buteo, Charadrius placidus , and listed by Cultural Heritage Administration were 6 species: Accipiter soloensis, A. nisus , A. gentilis, Falco tinnunculus, Otus scops, Ninox scutulata.

고온설비의 FFS평가를 위한 308 스테인리스강의 크리프 균열성장 재료물성에 대한 연구

이경용,백운봉,윤기봉 한국산업안전학회 2002 한국안전학회지 Vol.17 No.4

For fitness-for-service evaluation of high temperature plant components with defects, crack growth life must be assessed properly as indicated in the recent draft of API 579 code. Type 308 stainless steel has been widely used as a field weld material in the petrochemical industry. In this study, creep crack growth data of type 308 stainless steel are colleted and re-analyzed using C_t as a characterizing fracture parameter. A unique da/dt versus C_t relationship was obtained despite of difference of creep deformation constant or the reviewed materials and specimen geometry of the tested specimens. The obtained results can be employed for crack growth life assessment and fitness-for-service evaluation for the cracks in high temperature components. It is also argued that since the effect of creep properties and other material variability on the creep crack growth behavior would be minor the obtained model may be applied for most of the 308 stainless steels.

강박증 환자에서의 인격장애 공존병리에 관한 연구

이동우,강웅구,류인균,정도언,조맹제,우종인,김용식,권준수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : 강박증의 동반인격장애에 관한 연구들은 기존의 개념과 달리 강박성 인격장애와 강박증 간에는 특이적인 관계가 없으며, 강박증 환자들은 다양한 인격장애를 동반한다는 결과를 보여주었다. 그러나 이러한 연구들은 동반 인격장애에 관한 기술적인 분석에 그쳤고, 강박증 환자군의 임상 증상과 동반 인격장애 양상간의 연관성에 관한 분석을 시행하지 않았다. 본 연구의 목적은 강박증 환자군에서의 동반 인격장애를 평가하고 강박증 환자의 다양한 증상과 동반 인격특성 간의 연관성에 대해 연구하는 것이다. 방 법 : DSM-IV의 강박증의 진단기준을 만족하는 59명의 환자군과 32명의 정상대조군을 대상으로 인격장애 질문지를 적용한 후 4∼6점의 절단점을 기준으로 인격장애의 진단이 내려졌다. 먼저 환자군과 정상대조군 간의 특정 인격장애 빈도의 차이를 알아보기 위하여 Fisher's exact test를 시행한 후, 두집단 간에 유의한 차이가 있는 것으로 밝혀진 인격장애 척도 점수에 미치는 Y-BOCS,BDI,BAI점수의 영향을 알아보기 위하여 다중선형회귀 분석을 시행하였다. 결 과 : 1) Fisher's exact test 결과 강박증 환자군은 정상 대조군에 비해 경계성 인격장애(18.6%vs 0%, p=0.007). 회피성 인격장애(55.9% vs 18.8%, p=0.001), 우울성 인격장애(40.7% vs 0%, p=0.000)의 비율이 유의하게 높았다. 2) 다중선형회귀분석 결과 Y-BOCS 점수 (t=2.10, p=0.043)와 BAI점수(t=2.60, p=0.014)는 경계성 인격장애 점수에 유의한 영향을 주는 것으로 나타났다. 또한 BAI점수(t=3.23, p<0.003)는 회피성 인격장애 저수에, BDI점수 (t=3.08, p=0.004)는 우울성 인격장애 점수에 유의한 영향을 주는 것으로 나타났다. 결 론 : 강박증 환자군은 정상 대조군에 비해 회피성 인격장애, 우울성 인격장애, 경계성 인격장애의 동반율이 높고, 강박증이 경계성 인격장애의 심각도에 유의한 영향을 미치는 것으로 사료된다. The purpose of this study was to assess the comorbid axis-Ⅱ disorders of obsessive compulsive disorder(OCD) patients and to investigate the relationship between symptoms of OCD and the comorbid personality traits. The subjects were 59 patients who met DSM-IV criteria for obsessive-compulsive disorder and 32 normal controls. All subjects completed personality Disorder Questionnaire-IV(PDQ-IV). The patients completed Beck Depression Inventory(BDI) and Beck Anxiety Inventory(BAI), and were rated with Yale-Brown Obsessive Compulsive Scale(YBOCS). The results were as follows. 1) The OCD patients showed significantly higher prevalence of avoidant, depresssive and borderline personality disorder(p<0.01) compared to controls. 2) The BAI score had significant effect on the avoidant personality score(t=3,23, p<0.003). The BDI score had significant effect on the depressive personality score(t=3.08, p=0.004). The YBOCS(t=2.10, p=0.043) and BAI(t=2.60, p=0.014) scores had significant effects on the borderline personality score. We found that OCD patients had higher prevalence of avoidant, depressive, and borderline personality disorders. We also found that obsessive-compulsive symptoms have significant effect on the severity of borderline personalty traits. We suggest that it would be very helpful to consider Axis-Ⅱ disorders for managing patients with obsessive-compulsive disorder.