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농존지역 거주노인의 연령,성별,교육수준이 한국판 MMSE 점수에 미치는 영향에 관한 연구
우종인,이정희,홍진표 대한신경정신의학회 1996 신경정신의학 Vol.35 No.1
In order to observe the sociodemographic effects on Mini-Mental State Examination-Korean version(MMSE-K), MMSE-K was administered to the residents aged 65 and older in Yonchon county, Kyungki-Do. Following results were found : 1) Forty percent of the variance in MMSE-K scores was accounted by educatonal level, age and sex. 2) Educational levels were closely correlated with MMSE-K scores(r=0.49). The group of elementary school graduates and over scored higher scores of 5-6 points and 1- 3 points higher in comparison to the noneducated group and the elementary school failure group, respectively. 3) Men received higher MMSE-K scores than women, especially in the noneducated group and the elementary school failure group. In conclusion, readjustments of MMSE-K scores for demographic variables, especially for educational level, are necessary in order to use the MMSE-K as a screening measure for dementia.
정신분렬병의 혈소판 Monoamine Oxidase 활성도에 관한 연구
우종인,박찬웅,Woo, Jong-Inn,Park, Chan-Woong 대한약리학회 1982 대한약리학잡지 Vol.18 No.2
만성 정신분렬병 환자에서 성(性)에 따른 혈소판 MAO 활성도의 변화양상을 분석하고 이에 관련하여 혈장 Testosterone 및 Estradiol농도의 변화를 검토하고자, 135명의 정상대조군과 78명의 만성 정신분렬병 환자를 대상으로 하여 혈소판 MAO활성도와 혈장 Testosterone 및 Estradiol농도를 측정한 결과는 다음과 같다. 1) 만성 정신분렬병 환자에서 혈소판 MAO활성도는 남녀 모두 그 정상대조군에 비하여 낮은 사람이 더 많았다. 2) 혈소판 MAO활성도의 남녀간의 차이는 정상대조군에서는 없었지만 만성 정신분렬병 환자가 여자 환자에 비해 혈소판 MAO활성도가 낮은 사람이 더 많았다. 3) 남자 정신분렬병 환자에서는 혈장 Estradiol농도만 정상대조군에 비하여 저하되어 있었고, 여자 정신분렬병 환자에서는 혈장 Testosterone농도만 정상대조군에 비하여 저하되어 있었다. To investigate the relationship between platelet monoamine oxidase activity and serum levels of testosterone and estradiol in schizophrenic patient, 78 chronic patients were compared with 135 normal controls. 1) The monoamine oxidase activity of chronic schizophrenic group was lower than normal group. 2) In normal group, there was no sex difference in monoamine oxidase activity. But in chronic schizophrenic group, the monoamine oxidase activity in male was lower than female. 3) In male schizophrenic group, the serum estradiol level was lower than normal group. 4) In female schizophrenic group, the serum testosterone level was lower than normal group. The significances of relationship between platelet monoamine oxidase activity and sex hormones are discussed.
우종인 大韓神經精神醫學會 1990 신경정신의학 Vol.29 No.3
Even though the development of psychopharmcology has influenced on the exploration and the treatment of the psychiatric disorders, there are many difficult situations in psy-chopharmacological treatment. The author looked over the situations that could produce di-fficulties according to each step of the psychopharmacological treatment, and made some suggestions for the resolution of them : 1) The therapist should be well experienced and mastered. 2) The pharmacotherapy should be done psychotherapeutically. 3) Th psychopharmacotherapy should be individualized. 4) Short-term drug therapy at lowest effective doses should be the principle. 5) There should be well-equipped laboratories for plasma drug monitoring. 6) The elucidation of etiology and pathophysiology of mental illnesses should be prece-ded. 7) There should be development of new specific psychopharmacological drugs.