서울의 PPNG 발생 빈도(1991-1992)

김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.

갈바노메터를 이용한 고속 광스펙트럼 측정

김영관,전상민,김용평 경희대학교 산학협력기술연구원 2001 산학협력기술연구논문집 Vol.7 No.-

WBM system requires the accurate measurement of a real-time optical spectrum properties. In this study, we constructed an optical spectrum analyzer using a galvanometer and analyzed its properties. The measurement resolution is 0.1 nm, accuracy is ± 0.01 nm and sweep time is 1.5 ms in the C-band of WDM system.

살충성 O,O-Dimethyl-O-(3-Methyl-4-Nitrophenyl)-phosphorothioate (Sumithion^�)의 전기화학적 환원반응에 미치는 Micell의 영향

成洛道,明平根,朴勝熙,金日光 충남대학교 약학대학 의약품개발연구소 1986 藥學論文集 Vol.2 No.-

The electrochemical reduction of sumithion in various surfactants, LaLS, CTABr, Triton X-100 and in acetonitrile solution has been examined by DC, DP polarography and cyclic voltammetry (CV). Especially, in anionic surfactant, NaLS solution, the height of reduction wave is dramatic eliminated and half-wave potentials are shifted to strong negative potential (-2.7 volt vs. Ag-AgCl) by repulsion of nitro group in sumithion and anionic micell surfaces. The processes of reduction of sumithion were irreversibly electrochemical mechanism and the result of the reaction at high cathodic potential (-2.7 v. vs. Ag-AgCl), O,O-dimethyl-O-(3-methylhydoxyaminophenyl) phosphorothioate is formed as major product via O,O-dimethyl-O-(3-methylnitrosophenyl) phosphorothioate in NaLS micell solution.

살충성 O,O-Dimethyl-O-(3-Metyl-4-Nitrophenyl)-phosphorothioate (Sumithion^�)의 전기화학적 환원반응에 미치는 Micell의 영향

成洛道,明平根,朴勝熙,金日光 圓光大學校 基礎自然科學硏究所 1988 基礎科學硏究誌 Vol.7 No.3

The electrochemical reduction of sumithion in various surfactants, NaLS, CTABr, Triton X-100 and in acetonitrile solution has been examined by DC, DP polarography and cyclic voltammetry (CV). Especially, in anionic surfactant, NaLS solution, the height of reduction wave is dramatic eliminated and half-wave potentials are shifted to strong negative potential (-2.7 volt vs. Ag-AgCl) by repulsion of nitro group in sumithion and anionic micell surfaces. The processes of reduction of sumithion were irreversibly electrochemical mechanism and the result of the reaction at high cathodic potential (-2.7v. vs. Ag-AgCl), O,O-dimethyl-O-(3-methylhydoxyaminophenyl) phosphorothioate is formed as major product via O,O-dimethyl-O-(3-methylnitrosophenyl) phospho-rothioate in NaLS micell solution.

살충성 O,O-Dimethyl-O-(3-Methyl-4-Nitrophenyl)-Phosphorothioate (Sumithion^�)의 전기화학적 환원반응에 미치는 Micell의 영향

成洛道,明平根,朴勝熙,金日光 圓光大學校 基礎自然科學硏究所 1987 基礎科學硏究誌 Vol.6 No.3

The electrochemical reduction of sumithion in various surfactants, NaLS, CTABr, Trition X-100 and in acetonitrile solution has been examined by DC, DP polarography and cyclic voltammetry(CV). Especially, in anionic surfactant, NaLS solution, the height of reduction wave is dramatic eliminated and half-vale potentials are shifted to strong negative potential (-2.7 volt vs. Ag-AgCl) by repulsion of nitro group in sumithion and anionic micell surfaces. the processes of reduction of sumithion were irreversibly electrochemical mechanism and the result of the reaction at high cathodic potential (-2.7 volt vs. Ag-Agl) by repulsion of nitro group in sumithion and anionic micell surfaces. The processes of reduction of sumithion were irreversibly electrochemical mechanism and the result of the reaction at high cathodic potential (-2.7 volt vs. Ag-AgC1), O,O-dimethy1-O-(3-methylhydoxyaminophenyl) phosphorothioate is formed as major product via O,O-dimethyl-O-(3-methylhydoxyaminophenyl) phosphorothioate in NaLS micell solution.

宿主體內에서의 犬蛔충, 犬鉤충 및 肝吸충의 ¹³¹I-RISA 吸收分布

金相俊,鄭坪林,李根泰,高昌俊 中央醫學社 1977 中央醫學 Vol.33 No.1

Most of the parasites in nemathelminthes and platyhelrninthes have highly developed reproductive organs as 'compared with their digestive organs, and deposit heavily protein-rich eggs. One female adult of Ascaris lumbricoides lays more than 200, 000 eggs per a day, a female of hookworm more than 20, 000 eggs and more than 4,000 eggs from an adult of leaf-like liver fluke with length of 1. 0 to I.5cm. It is considered that these eggs-depositing parasites may take nutrients not only through degenerated mouth part but also through any other absorption mechanism, especially for the compensation of protein loss due to egg deposition From this viewpoint, an autoradiographic study was carried out for investigating the intake mechanism of protein into the above-mentioned parasites. Toxocara canis and Ancylostonza caninum were infected to the dogs, and Clonorchis sinensis was infected to the rabbits for the present study. A serum albumin for radioisotope, 1311-RISA, was also injected intravenously into each host, which was sacrificed 48 hours after injection The parasites were removed from the sacrificed hosts, and then the quantitative distribution of radioactivity were counted by Well Type Scintillation Counter from the parasites. The results are as follows; 1. Toxocara canis The dog ascaris harboring freely in the intestinal lumen of the host takes protein from the host through the cuticle as well as the primitive mouth :_. Part. Absorption amount of, serum protein was 1.2m; Ci per gm. Of body weight of the parasite and the absorption rate .was. 0.6%. The results indicate that the parasites take protein mainly from the contents of intestinal' lumen regardless of direct absorption from the intestinal wall of the host. 2. Ancylostoma caninum Canine hookworm intakes serum protein from the host only with its mouth part. Absorption amount .bf serum protein was 100.8 mpCi per gm. Of body weight of a parasite and 50.4% of absorption rate. Absorption amount of serum protein was actually 85 times higher than that of Toxocara canis. It is showed that blood-sucking through the mouth part with 3 pairs of teeth, is enough for protein metabolism in the canine hookworm. 3. Clonorchis sinensis The liver fluke inhabiting in the bile duct of the host liver, intook serum protein of the host with the oral sucker and integument. Absorption amount of serum protein was 60.0 mpCi per gm. Of body weight of the worm. The absorption rate (30.0%) was 50 times higher than that of Toxocara canis. It is suggested that serum protein is intaken from bile juice and wall of the host bile duct through the integument as well as the oral sucker of the liver fluke.

Mirizzi 증후군의 변형된 분류와 치료

김형철,강길호,채만규,김성용,백무준,이문수,박상흠,이문호,김창호,송옥평,조무식,박희주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Purpose : The Mirizzi syndrome is relatively rare and preoperative diagnosis of this disease is difficult. In 1978, Morelli suggested the subclassification of the Mirizzi syndrome into acute or chronic form. We experienced 5 cases of acute form. We analysed clinical features, preoperative radiologic findings and operative findings of 18 cases including acute forms which were diagnosed as Mirizzi syndrome and should suggest the modified classification of Mirizzi syndrome for choice of appropriate treatment. Method : From January 1995 to December 1998, 18 cases, of which 8 cases were diagnosed at Soonchunhyang University Chunan Hospital, and 10 cases were reported in the Korean Journal were retrospectively analysed with regard to clinical features, preoperative radiologic findings and operative findings. According to the clinical features, whole cases were divided into type Ⅰ(acute form) and type Ⅱ(chronic form) and then each type of cases were subclassified according to preoperative radiologic findings and operative findings. Results : Of 18 cases there were 5 cases in type Ⅰ(27.8%), 13 cases in type Ⅱ(72.2%). Type Ⅱb was most common. Type Ⅰa cases were treated only with cholecystectomy. We applied cholecystectomy, T-tube choledochostomy and patch technique in type Ⅰb and thpe Ⅰc cases. Cholectystectomies including removal of gallstones and internal drainage procedures were done in type Ⅱ chronic forms. Conclusion : The acute form(Type Ⅰ) of Mirizzi syndrome was suggested by Morelli might be subclassified into typeⅠa,Ⅰb and Ⅰc following the presence of the necrotic defect in common hepatic duct. Through the modified classification of Mirizzi syndrome based on clinical feature, preoperative radiologic findings and operative findings, we can choice appropriate treatment.

OCT 시스템을 위한 이중 광경로 지연기와 PZT 광경로 지연기에서의 편광모드분산 및 열요동 보상

김영관,박성진,김용평 경희대학교 레이저공학연구소 2004 레이저공학 Vol.15 No.-

In this study, a duplex scanning optical delay line is implemented and characterized for optical coherence tomography. The reference and sample arms in Michelson interferometer are simultaneously scanned by use of two identical piezoelectric transducers (PZT). It is obtained that scanning range, thermal drift, repeatability, and axial scanning velocity of duplex optical scanning delay line are distinctly superior to those of single scanning optical delay line.

직장암 수술 후 국소재발과 예후

김태윤,백무준,김성용,신응진,박내경,이문수,김창호,송옥평 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Locally recurrent rectal cancer is a difficult clinical problem. Local recurrence following treatment for rectal cancer is a major cause of morbidity and mortality. The reported range of local recurrence rates following surgical treatment for rectal cancer has varied from 4% to 50%. We retrospectively reviewed the charts of 142 rectal cancer patients from January 1991 to December 1999. Analysis of patients factors included age, gender, type of surgery, and adjuvant therapy. Tumors were assessed for level, stage, and grade. Local recurrence and distant metastases were also documented. Variables influencing local recurrence in this group were identified and disease-free survival is determined. Of the 142 patients(74 males, 68 females; mean age 62.6 years), 137 consecutive patients operated on for rectal cancer and followed up to December 2000 (range 23-118months) were analyzed. Local recurrence rate was 18.3%. Age and sex of patients, type of surgery, location of tumor in the rectum, size, morphology and grading of the tumor were all unrelated to the event under investigation. At Cox regression, the Dukes stage and the postoperative radiotherapy were the only independent prognostic factors for local recurrence, and Dukes stage (Hazard ratio=2.89, p<0.001) and local recurrence (Hazard ratio=3.31, p<0.01) were the only independent factors associated with improved survival.