物價의 巨視經濟變數에 대한 動態的 波及效果分析

崔成哲,周修鉉 釜山 外國語 大學校 1995 外大論叢 Vol.13 No.1

The Purpose of this study is to empirically analyze time series model for the dynamic effect of prices on macroeconomic variables. For this purpose, Vector Error Correction Model composed of seven variables is estimated as a prices forecast model. Maximum likelihood estimation is applicated to estimate VECM following Johansen(1988). The forecast experiments is based on the model for sample periods that begin in the first quarter 1970 and end fourth quarter 1992. In general, the analysis attempts to address the general conclusion that has emerged from the study of such VAR that most of dynamic interactions among the key variables can best be explained as. The VAR system is an atheoretic model that captures the statistical relations among various macroeconomic time series. We have tried stationarity of variables with unit root test and cointegration test. Both of the likelihood ratio-the trace test and the maximum eigenvalue test-fail to reject the hypothesis that three or fewer cointegrating at the 5 percent level exist. Thus, three cointegrating vectors were found in the system that include seven variables, and hence this system was estimated as a VECM(vector error correctiion model) As a result of VECM, the dynamic effect of macroeconomic variables of demand side on prices is larger than that of macroeconomic variables of supply side. Though we could not find that wage, interest rate, export and import affect prices from Granger-causality test, we have found prices does Granger-caused by consumption, investment. We could find the following facts by means of variance decomposition at the twenty-four quarter horizon. Results show that innovations in consumption, investment account for more than the other variables share of the variance of prices under orderings presented. The results above means that demand factors is not only the major determinant of prices but also the important variable which influences the price directly. Furthermore it can be implied that prices is determined not by supply factors but by demand factors.

12주간의 운동프로그램이 노인의 근력과 근지구력에 미치는 영향

최종환,김종성,조경욱,김태완,김현주 충북대학교 평생체육연구소 2000 平生體育硏究所 論文集 Vol.12 No.-

The purpose of this study was to determine the effect of 12-week exercise program on isokinetic muscular strength and endurance in the elderly women(n=32, age=66.78±4.01). They were tested on their muscular strength and endurance at the beginning and at the end of the 12-weeks study(pre-post tests). Muscle strength was evaluated by peak torque of the knee extensor and flexors at 60 deg/sec(5 repetitions) and Endurance was assessed by total work of the knee extensor and flexors at 120 deg/sec(15 repetions) using isokinetic exercise machine(Biodex system II, U.S.A.). For data analysis, Mean and Standard Deviation scores were calculated, and paird t-test was used. This study resulted in as follow; First, after 12-week exercise program, muscular strength of right and left knee flexors was significantly improved. Second, after 12-week exercise program, endurance of right and left knew flexors was significantly improved. In conclusion, regular exercise delays decline of muscular strength and endurance or improves muscular strength and endurance in elerly. It will have an effect on essential life of elderly, improve quality of life.

韓國 信用割富의 巨視經濟效果에 대한 計量分析

최성철,주수현 釜山 外國語 大學校 1997 外大論叢 Vol.16 No.1

The interest rate is the adjustment mechanism in loan markets. An equilibrium has seldom acquired in loan markets because of characteristics of loan markets such as default risk, borrower classification, customer relationships, and imperfect imformation. Credit rationing can be defined as a situation in which there exists an excess demand for loans because quoted loan interest rates are below the Walrasian market clearing level. Generally, firms which request loans for the investment act as promary borrowers in loan markets. The availability of credit affects the amount of investment. So, credit rationing affects macroeconomic varibles through the investment of firms. The purpose of this study is to analyze the macroeconomic effects of credit rationing. For this prupose, we have examined the effects of credit rationing on real GNP, price level, interest rate of private bonds, and investment. We have tried stationarity of variables with unit root test and cointegration test. Then, we have applied vector error correction medel to variables which have stationary relation.

외안각 절제술과 경결막 절개에 의한 안와 접근법

정종철,김성범,서지훈,송민석,전창훈,최세훈,김현민 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4

Various surgical approaches to the orbits have been used. But the transconjunctival approach, also called the inferior fornix incision, provides adequate access to the orbital floor with esthetic results. Additionally, transconjunctival approach with lateral canthotomy allows more wide surgical field and good access to the orbital area. Generally, preseptal approach is more used rather than postseptal approach in the transconjunctival incision for the prevention of fat herniation during surgery. There are some complications in transconjunctival approaches but these complications can be prevented with careful surgical techniques. We report clinical results in 12 patients who were treated by preseptal transconjunctival incision with lateral canthotomoy for the treatment of orbital trauma. We were satisfied with this technique for reduction and reconstruction of the orbital trauma and we could also observe relatively good esthetic results.

급성 신부전증을 초래한 Wegener씨 육아종증 1례

박일,임영국,최성도,임현성,정종훈,문철웅 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

호흡기 증상과 급성신부전증이 발생된 환자에서 혈액검사, 혈청학적 검사, 방사선학적 검사, ANCA test 및 신생검을 통하여 Wegener씨 육아종증을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 본질환이 재발하는 경우는 cyclophosphamide에서 azathioprine으로 치료약을 바꾸었을때나 특히 ANCA 반응이 양성으로 지속시 발생한다. Godman과 Churg는 상기도의 괴사성 육아성 병변, 하기도의 괴사성 혈관염, 국한성 신사구체염을 진단의 지표로 삼았다. 특히 상기도 점막의 생검 소견상 괴사성 육아성 혈관염이 보이면 일단 본 증을 의심하고 폐 생검과 신 생검이 필요로 한다. Wegener's Granulomatosis is an uncommon disease which is characterized by granulomatous vasculitis of both lung and kidney. Although the cause is unknown, it's suggesting that disordered immunity with both antibody and cell-mediated tissue damage occurs. The disease affects patients of any age. Characteristic clinical manifestations are diverse but in clude saddle nose deformity, sinusitis, productive coughing, myalgia, fever etc. Characteristic laboratory abnormalities include elevated ESR, neutrophilic leukocytosis, anemia and positive test for ANCA test. Renal biopsy is important for diagnosis. The treatment of choice is a combination of corticosteroid and cytotoxic agent. A53-year-old woman was admitted to our hospital because of productive coughing, short of breathing, oliguria, nausea, and vomiting. Three months ago, she was suffered from general weakness, poor appetite, tingling sensation on extremity, and loosely stool. Twenty days ago, above symptoms were aggravated, she admitted local clinic. Six days ago, because of CBC showed anemia , she was done transfusion. During transfusion, she was developed urticaha then productive coughing, dyspnea, increased serum BUN and creatinine levels. She was transferred to our hospital under the impression of ARF. On the admission, she was chronic ill-looking appearance with pale conjunctiva, tachypnea, dyspnea, and cold sweating. We have checked the patient by CBC, serum and serologic test, X-ray, ANCA test, renal biopsy. With renal biopsy microscopic examination study revealed necrotizing vasculitis, We treated a combination therapy with methyl-PDS and cyclophosphamide. She had a good response. So we report wegener's granulomatosis with the review of relevant literature.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

退行性關節炎 韓方治療에 對한 最近 硏究 動向 : 臨床硏究 方法論을 中心으로 Herbal Medicines in the Treatment of Osteoarthritis in Pubmed and Chinese Medical Journals

서병관,류성룡,이송실,허정은,백용현,이재동,최도영,조윤제,김남재,박동석 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

Predicting Full Bloom Date of ‘Niitaka’ Pear by using Temperature after Flower Bud Burst

Seong-Tae Choi,Mi Geon Cheon,Seo Hyeon Lee,Kyoungmi Park,Yeon Hyeon Hwang,Young Ho Chang 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.5

Korean Multicenter Study of Infectious Complications after Transurethral Prostate Surgery in Patients with Preoperative Sterile Urine

Seong Hyeon Yu,정승일,Eu Chang Hwang,김태형,최재덕,유구한,Jeong Woo Lee,Dong Hoon Koh,Sangrak Bae,Seung Ok Yang,Joongwon Choi,Seung Ki Min,Hoon Choi 대한요로생식기감염학회 2022 Urogenital Tract Infection Vol.17 No.3

Purpose: To evaluate the efficacy of antibiotic prophylaxis and determine the risk factors of infectious complications after transurethral surgery of the prostate. Materials and Methods: Seven hundred and seventy-two patients who underwent transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HOLEP) were reviewed. Of these, this study enrolled 643 patients without bacteriuria who had not received antibiotics for urinary tract infections for two weeks before surgery. The patients were divided into two groups according to the duration of the antibiotics (Group 1: less than one day, n=396 vs. Group 2: more than one day, n=247). Results: The overall incidence of postoperative infectious complications in 643 patients was 5.0% (32/643). When postoperative infectious complications were compared according to the duration of the antibiotics (Group 1 vs. Group 2), the infectious complications rates were 5.6% (22/396) vs. 4.0% (10/247), respectively (p=0.393). When postoperative infectious complications were compared according to the duration of antibiotics (Group 1 vs. Group 2) in the TURP and HOLEP groups, the infectious complications rates were 6.3% (12/192) vs. 1.0% (1/103) (p=0.035) and 4.9% (10/203) vs. 6.0% (8/134) (p=0.677), respectively. The duration of Foley catheterization was independently associated with infectious complications (p=0.003). Conclusions: The results showed that prolonged postoperative catheterization affects postoperative infectious complications associated with transurethral prostate surgery. Although antibiotics administered for less than one day are effective for antibiotic prophylaxis of transurethral prostate surgery, a longer antibiotic therapy is recommended for TURP.

Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A

Choi, Yoon Seok,Jung, Min Kyung,Lee, Jeewon,Choi, Seong Jin,Choi, Sung Hoon,Lee, Hyun Woong,Lee, Jong-Joo,Kim, Hyung Joon,Ahn, Sang Hoon,Lee, Dong Hyeon,Kim, Won,Park, Su-Hyung,Huh, Jun R.,Kim, Hyoung Elsevier 2018 Gastroenterology Vol.154 No.4

<P><B>Background and Aims</B></P> <P>CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP> T-regulatory (Treg) cells control immune responses and maintain immune homeostasis. However, under inflammatory conditions, Treg cells produce cytokines that promote inflammation. We investigated production of tumor necrosis factor (TNF) by Treg cells in patients with acute hepatitis A (AHA), and examined the characteristics of these cells and association with clinical factors.</P> <P><B>Methods</B></P> <P>We analyzed blood samples collected from 63 patients with AHA at the time of hospitalization (and some at later time points) and 19 healthy donors in South Korea. Liver tissues were collected from patients with fulminant AHA during liver transplantation. Peripheral blood mononuclear cells were isolated from whole blood and lymphocytes were isolated from liver tissues and analyzed by flow cytometry. Cytokine production from Treg cells (CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP>) was measured by immunofluorescence levels following stimulation with anti-CD3 and anti-CD28. Epigenetic stability of Treg cells was determined based on DNA methylation patterns. Phenotypes of Treg cells were analyzed by flow cytometry and an RORγt inhibitor, ML-209, was used to inhibit TNF production. Treg cell suppression assay was performed by co-culture of Treg-depleted peripheral blood mononuclear cells s and isolated Treg cells.</P> <P><B>Results</B></P> <P>A higher proportion of CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP> Treg cells from patients with AHA compared with controls produced TNF upon stimulation with anti-CD3 and anti-CD28 (11.2% vs 2.8%). DNA methylation analysis confirmed the identity of the Treg cells. TNF-producing Treg cells had features of T-helper 17 cells, including up-regulation of RORγt, which was required for TNF production. The Treg cells had reduced suppressive functions compared with Treg cells from controls. The frequency of TNF-producing Treg cells in AHA patients’ blood correlated with their serum level of alanine aminotransferase.</P> <P><B>Conclusions</B></P> <P>Treg cells from patients with AHA have altered functions compared with Treg cells from healthy individuals. Treg cells from patients with AHA produce higher levels of TNF, gain features of T-helper 17 cells, and have reduced suppressive activity. The presence of these cells is associated with severe liver injury in patients with AHA.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>