개에서 발생한 이버멕틴 중독증 1례

여동원,윤기영,박정호,이왕희,송근호,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

A 1-year old, intact male Jin-do dog with ataxia, hypersalivation and anorexia was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Ivermectin toxicosis was diagnosed by the history taking, clinical signs, physical examination and neurological examination. After therapy with intravenous fluid and lipid emulsion administration, the clinical signs were found to have significantly improved.

관동맥연축의 비침습적 진단에 있어 Ergonovine Echocardiogrpahy의 유용성

송재관,박성욱,김재중,두영철,김원호,박승정,이종구 울산대학교 의과대학 1992 울산의대학술지 Vol.1 No.1

관동맥연축의 비침습적인 진단방법의 확립은 침습적인 관동맥조영술 및 연축유발검사에 비해 반복적용이 가능한 이론적인 장점이 있어 선별검사(screening test)로서의 기능뿐만 아니라 치료로 이용되는 약물의 효과비교 및 추적검사를 통한 관동맥연축의 임상ㄹ활동도 평가등에 손쉽게 이용될 수 있으라라 예상된다. 이에 저자들은 ergonovine 투여시 기록된 좌심실벽운동장애 유무가 갖는 관동맥연축에 의한 심근허혈의 진단적 가치를 평가하기 위해 Beside Ergonovine Echocardiography Test를 시행하였다. 관동맥조영술 및 연축유발검사에서 변이형협심증으로 증명된 30명(남자 27명, 평균연령 54세)과 비특이적인 흉통질환군 20명(여자 12명, 평균연령 55세)을 대상으로 관동맥조영술 다음날 ergonovine test를 시행하였다. 운동부하검사가 음성인 환자들을 대상으로 6시간 공복시킨 뒤 앙와위에서 상지정맥을 통하여 25-50microgram(이하 mcg)을 5뷴 간격으로 투여하여 흉통의 유무, 심전도 및 이면성심초음파를 5분마다 기록하였으며 총투여량이 350mcg에 도달하거나 양성반응을 보이는 경우 nitroglycerin 250mcg 정주 및 설하투여로 종료하였다. 좌심실벽운동의 분석은 side-by-side continuous cine-loop display가 가능한 QUAD screen 방법으로 판별하였다. 가역적인 심전도 변화나 국소적인 심실벽운동장애가 유발되는 경우를 양성으로 판정하였다. Ergonovine Echocardiography의 전체 민감도는 90%, 특이도는 100%로 동시에 기록된 심전도 변화의 민감도(73%)보다 높았으며 특히 흉통이 있으나 심전도 변화가 전혀 없었던 5례 모두에서 좌심실벽운동장애가 관찰되어 본 검사법의 우월성을 확인할 수 있었다. 양성반응을 보인 ergonovine 평균 투여량이 173±95mcg 이었으며 흉통발작의 빈도를 기준으로한 임상활동도가 높은 경우 활동도가 낮은 군에 비해 양성반응을 의한 총 ergonovine 투여량이 적었으며(123±86 vs 213±83mcg, p<0.01) 관동맥협착이 연축에 동반되어 있는 경우 정상 관동맥에 연축이 있는 경우보다 민감도가 더 높았다(100% va 60%, P=0.02). Ergonovine 투여로 혈압은 기저치 보다 약 17%정도 증가되었으나 맥박수는 큰 변화를 나타내지 않아 안전하게 시행될수 있었으며 오심, 두통, 견갑부통증, 심실기외수축, 방실차단 등이 소수례에서 관찰되었으나 검사로 인한 사망례는 없었다. Ergonovine 주입후 기록된 좌심실벽운동동장애는 심전도 변화보다 더 민감하게 관동맥연축에 의한 심근허혈을 진단할 수 있었으며 Ergonovine Echocardiography는 운동부하검사 등으로 심한 관동맥협착이 배제된 선별된 흉통환자들에서 관동맥연축의 진단에 안전하게 시행될 수 있는 민감하고 특이도가 높은 검사방법이며 변이형협심증의 임상활동도와 관동맥협착의 동반유무가 본 검사법의 결과에 영향을 미칠 수 있으리라 사료된다. The purpose of this study was to evaluate the clinical feasibility of bedside intravenous ergonovine test with echocardiography as a noninvasive diagnostic method for coronary vasospasm. Bedside ergonovine test was performed in 50 patients with chest pain one day after coronary angiography with spasm provocation test;30 patients showed positive results of provocation test while in 20 patients there was no evidence of coronary vasospasm. A bolus of ergonovine maleate(.025 or .05mg) was injected at 5 min intervals up to total cumulative dosage of 0.35mg, and 12-leads ECG and 2-D Echo were recorded every 3min after each injection. Left ventricular wall motion was analyzed with a commercially available ' QUAD' system. The positive criteria of beside ergonovine test included reversible ST segment elevation or depression, T wave changes in ECG(ECG criteria) and reversible regional wall motion abnormalities(RWMA) in Echo(Echo criteria). The overall sensitivity and specificity of ECG criteria were 73%(22/30) and 100% respectively ; The sensitivity of Echo criteria increased up to 90%(27/30) without the change of the specificity. Among 22 patients with reversible ECG changes only 73%(16/22) showed typical ST segment elevation while ST depression was recorded in 2 patients(9%) and minor T wave peaking or flattening without ST segment displacement in 4 patients(18%). Concomitant fixed coronary lesion does increase the sensitivity of the test compared to pure coronary vasospasm with ECG criteria(100% vs 60%, p<0.05). Mean does of ergonovine with positive results was 173±95 microgram(mcg) and the amount of does of ergonovine for positive result was significantly larger in patients with low disease activity (chest pain <5times/자) than those with high disease activity(213±83 vs 123±86mcg, p<0.01). There was no procedure related mortality or fatal arrhythmias. Ergonovine echocardiography is a highly sensitive and specific test for coronary vasospasm and is safe in selected patients in whom the exercise test is negative and severe fixed coronary artery disease has been excluded. Presence of concomitant fixed coronary artery disease and the degree of clinical activity of coronary vasospasm may influence the results of this test.

자동화학검사용 영동시약의 평가

이성규,공선영,송선미,이수연,김종원 대한임상검사정도관리협회 1992 臨床檢査와 精度管理 Vol.22 No.2

운동수행능력에 따른 경기 분석

김승일,송진석,강유원,오유성,김용무 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

The purpose of this study was to examine the nature and characteristics of competitive aspect in sporting experience through phenomenological approach. The conclusion was followings: 1. The classified characteristics and result of tough and individual game are appeared in double with classification of meaning category in the physical contacting games. Physical contacting games were mostly appreared toke tough games. Thus, human relationship would be meaning ful in the physical contacting games. The meaning ful category (which is experienced in the competitive aspect of physical contacting game) reflects the characteristics of meaning category experienced in group game. 2. The results of the study indicated that to be time and body affect in women sport such as basketball, bowling, and taekwondo while, body and space influence men sport such as football, golf, boxing, judo and taekwondo and so on.. 3. I could find that the elements of meaning category of participants in this study through experience of competition of non-physical contacting games such as golf, shooting, bowling, skiing etc reflect the elements of meaning category in individual games. This would be caused by that probably the sporting events that doesn't need physical contact are mostly individual games. The common meaning category of participants of non-physical contacting games in this study show time and body. It provides and opposite view about common opinion that non-physical contacting games are static and not active by its attribute of the games. The vivid time and body that are meaning categoty experienced with non-contacting games show that they are the field of vivid meaning experience on the assumption of live movement which th competitive aspect is alive.

접합면의 차이에 따른 두개골 외판의 생존

박성근,송중원,한기환,강진성,박관규 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.3

Onlay graft of the calvarial bone has been popularized in craniofacial surgery because absorption of the calvarial bone is less than that of the endochondral bone. But the problems with using the calvarial bone are its rigidity and difficulty in setting a precise apposition. When the outer tables of the calvarial bone are used for augmentation and reconstruction of the convex zygoma, forehead, or chin, it is better to place the cancellous surface over the convex recipient bone to get a precise apposition. Whereas, it is better to place the cortical surface over the concave nose or orbital cavity to achieve a good apposition. Therfore, our study was designed to determine the differences of bone absorption and regeneration between cancellous and cortial bone contact to facial bone, and between preserved periosteum and detached periosteum in autograft of calvarial bone in dog models. Outer tables of the calvarial bone were placed in subperiosteal pockets of the upper and lower maxilla in four different ways : Group I ; The cancellous surface was placed in contact with the bare recipient bone, and the cortical surface attached with periosteum was accordingly contacted with the elevated periosteum of the recipient bone. Group Ⅱ ; The corical surface attached with periosteum was placed in contact with the bare recipient bone and the cancellous surface was contacted with the elevated periosteum of the recipient bone, Group Ⅲ ; The arrangenent was similar to Group Ⅰ except that the periosteum of the graft was deprived. Group Ⅳ ; The arrangement was similar to Group Ⅱ except that the periosteum of the graft was deprived. Volume measurements using a caliper technique and histological study were made 20 weeks postoperatively. The volume of maintenance is as follows ; Group Ⅰ, 84.2% ; Group Ⅱ, 77.6% ; Group Ⅲ, 77.0%, and Group Ⅳ, 69.5%. The histolgical contribution of living bone was assessed by a modified point counting technique : Group Ⅰ, 86.6%, Group Ⅱ, 83.8% ; Group Ⅲ, 79.6% and Group Ⅳ, 77.6%. Greater volume maintenance and histological contribution of living bone were found when cancelllous surface rather that the cortical were placed in contact with the recipient bone and the grafts from their periosteum were preserved. We concluded that in order to expect better survival of a grafted bone, the cancellous surface of the graft should contact with the recipient bone and that the periosteum of the graft should be preserved.

마이크로파 용융삽입법을 이용한 생분해성 나노복합체의 제조

하원조,신준식,송승욱,김준호,손세모,박성수 한국환경과학회 2004 한국환경과학회지 Vol.13 No.4

The purpose of this study was to investigate the possibility of application of microwave energy for the fabrication of polymer/clay nanocomposite. APES/Clay nanocomposites were prepared at 130℃ for 30min with various content of clay by melt-intercalation method under classical and microwave heating source. APES/Clay samples were characterized by the means of X-ray diffractometry(XRD), thermal gravimetric analysis(TGA), and rheometric dynamic analysis(RDA). It was found that intercalated or exfoliated state was obtained in the samples according to the condition of organic modification, clay content, and heating source.

해석적기법 및 비파괴시험에 의한 콘크리트 포장슬래브의 잔존수명추정에 관한 연구

이승원,송재호 金烏工科大學校 1996 論文集 Vol.17 No.-

To predict of remaining life of cement concrete pavement slabs, both nondestructive tests and analysis procedures have analyzed in this study. Therefore it is concluded, after analysis of merits and demerits of the various analysis procedures and nondestructive tests, coupled finite element analysis is the most effective procedure and FWD(Falling Weight Deflectometer) is the most suitable nondestructive test. Through the analysis procedure considering structural failure due to load repetition, failure equation is developed. The developed failure equation is compared with existing failure equations. And load repetition for failure for domestic concrete pavement. slabs is calculated

국내에서 분리된 Extended-Spectrum β-Lactamase 생성 Escherichia coli와 Klebsiella pneumoniae의 빈도 및 유형

홍성근,김선주,정성훈,장철훈,조성란,안지영,신종희,이혜수,송원근,어영,염종화,용동은,이경원,정윤섭 대한임상미샐물학회 2003 Annals of clinical microbiology Vol.6 No.2

자동화학검사용 인화시약의 평가

이성규,공선영,송선미,이수연,김종원 대한임상검사정도관리협회 1992 臨床檢査와 精度管理 Vol.22 No.2

代體醫學을 利用한 肥滿治療의 實際

이성덕,宋泰元 대전대학교 한의학연구소 2000 혜화의학회지 Vol.9 No.1

This case study was done on a 37 year old female patient at the department for rehabilitation in Bundang Cha Oriental hospital who was treated for 70 days by traditional Acupuncture and Herbal medicine therapy as well as fasting with saengshig(生食), air bath(風浴) and cold-hot-bath(冷溫浴) for skin revitalisation, furthermore by Doinangyo(導引按??) and exercise for improvement of general condition and colon-hydrocleansing. The results are as following: 1.The body weigth was reduced by 14.5㎏ from 87.4㎏ to 72.9㎏ 2.The obesity degree reduced from 159% to 133% 3.The BMI reduced from 33.3 to 27.8 4.The WHR reduced from 0.96 to 0.88 5.The amount of body fat reduced by 7.7㎏ from 27.2㎏ to19.5㎏ 6.The fat distribution of the abdomen reduced from 0.92 to 0.85 7.The percent body fat was reduced from 31.1% to 26.7% 8.Except of a mild systemic pruritus the clinical symtoms like kneepain, fatigue, chilling, headache, indigestion, menorrhalgia improved significantly.