필리핀 여행 후 발생한 쯔쯔가무시병 1예

김계형,김낙현,김문석,김충종,전재현,박완범,장원종,박상원,김익상,오명돈,최강원 대한감염학회 2008 감염과 화학요법 Vol.40 No.6

Infectious diseases imported from other countries have increased as more and more Koreans are going abroad for various purposes. Tsutsugamushi disease from other endemic area such as Southeast Asia is important, because it can occur in any season and eschar may be absent. We report a case of imported tsutsugamushi disease acquired in the Philippines. A patient presented with fever, headache, and maculopapular skin rash. However, eschar was absent. Polymerase chain reaction (PCR) for 56-kDa gene of Orientia tsutsugamushi using buffy coat was positive. Serum indirect immunofluorescent antibody assay was initially negative but became positive with a titer of 1:320 at follow-up, Sequencing analysis revealed the strain to be 100% identical to the TW73R strain identified in Taiwan. After the patient received doxycycline, body temperature normalized in 12 hours. Tsutsugamushi disease is one of the differential diagnoses that should be included for patients with fever who have recently returned from Southeast Asian countries. PCR for O. tsutsugamushi using patient's buffy coat was useful for early diagnosis.

두부 위치 변화에 따른 파노라마 방사선사진상의 치축각도의 왜곡

전현상,최갑림,임성훈,김광원 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.4

본 연구는 파노라마 방사선사진에서 두부 위치 변화에 따라 인접 치아장축 사이에 이루는 각도가 어떻게 변화되는 지 알아보기 위해 시행하였다. 정상교합자의 모델을 기초로 하여 3차원 solid 모델을 구성하고 이를 신속 조형모델(rapid prototyping, RP)로 제작하였다. 다음 9가지 두부위치들을 5주 동안 일주일 간격으로 재위치시키고 촬영하였다: ideal head position, 5^(o), 10^(o) up, 5^(o), 10^(o) down, 5^(o), 10^(o) right up, and 5o,^(o) 10^(o) right rotation. 파노라마 방사선사진 촬영은 디지털 방사선 촬영기(Planmeca ProMax)를 이용하였고 모니터상에서 직접 인접 치아장축을 표시하고 그 사이 각도를 계측하였다. 그 결과 이상적인 두부 위치와 다양한 두부 위치 변화에 따라 촬영한 파노라마 방사선사진 사이에 인접 치아장축 사이의 각도가 대부분 유의한 차이를 보였다. 수평축(X축)을 중심으로 고개를 든 경우, 각 치아 들의 장축이 교합평면을 향하여 수렴하는 경향을 보였고 고개를 숙인 경우에는 치근단측을 향하여 수렴하는 경향을 보였으며, 이는 특히 전치부에서 가장 큰 차이를 보였다. 전후방축(Y축)을 중심으로 좌우측으로 고개를 기울인 경우, 교합평면이 올라간 쪽의 치아장축은 치근단측을 향하여 수렴하는 경향을 보였고 교합평면이 내려간 쪽은 교합평면을 향하여 수렴하는 경향을 보였다. 수직축(Z축)을 중심으로 고개를 좌우로 회전시킬 때, 고개를 돌린 쪽의 측절치와 견치는 치근단측을 향하여 수렴하고 반대측의 측절치와 견치는 교합평면을 향하여 수렴하였다. 이상의 결과들로 볼 때 파노라마 방사선사진 촬영 시 두부의 위치 변화에 따라 치근 평행도가 달라지기 때문에 환자를 올바르게 위치시키는것이 중요하며, 교정 환자에서 파노라마 방사선사진을 이용하여 치근 평행도를 평가할 때 교합평면의 경사(전후방,좌우측방)나 악궁의 비대칭 등이 반드시 고려되어야 할 것이다. Objective: The purpose of this study was to evaluate the effect of head position changes on the root parallelism between adjacent teeth on panoramic radiographs. Methods: A model with normal occlusion was constructed in the SolidWorks program, then RP (rapid protyping) model was fabricated. The model was repeatedly imaged and repositioned five times at each of the following nine positions: ideal head position, 5^(o), 10^(o) up, 5^(o), 10^(o) down, 5^(o), 10^(o) right up, and 5o,^(o) 10^(o) right rotation. Panoramic radiographs were taken by Planmeca ProMax and the angle between the long axes of adjacent teeth was directly measured in the monitor. Results: Axes of adjacent teeth tended to converge toward the occlusal plane when the head tilted up and converged in the opposite direction to the occlusal plane when the head tilted down. Anterior teeth showed the most notable differences. When one side of the head tilted up 5o and 10o along the anteroposterior axis (Y axis), tooth axes of the same side tended to converge toward the occlusal plane and tooth axes of the opposite side tended to converge in the opposite direction to the occlusal plane. When the head rotated to one side along the vertical axis (Z axis), the canine and lateral incisor of the same side converged in the opposite direction to the occlusal plane and the canine and lateral incisor of the other side converged toward the occlusal plane. Conclusions: When assessing the root parallelism on panoramic radiographs, the occlusal plane cant (anteroposterior or lateral) or asymmetry of the dental arch should be considered because these can cause distortion of tooth axes on panoramic radiographs.

악성 섬유성 조직구종의 기원에 관한 면역조직화학적 및 초미세형태학적 연구

전호종,임성철,강종식,김일,황호원 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.15 No.1

Malignant fibrous histiocytoma(MFH) was first terminologically introduced in 1963 to refer to a group malignant soft tissue tumors characterized by a stonform growth pattern and these tumors are a oup of sarcomas composed of cells morphologically resembling fibroblast and histiocvte. The histogeisis of MFH is still controversial, but a more complete appreciation of it's morphogenesis has been ovided by tissue culture and ultrastructural studies. In the present study, ultrastructural and immunohistochemical studies of seven cases of MFH disclosee maturation and development of principal types of cells constituting MFH and immunohistochemical actions to investigate the histogenesis of malignant fibrous histiocytoma. The results obtained were as follows. Malignant fibrous histiocytoma composed of different portions of fibroblast-like cells, histiocyte-like cells, cells intermediate between histiocyte-and fibroblast-like cells, multinucleated giant cells, undif ferentiated cells, xanthomatous cells and myofibroblast. The principal cell types of malignant fibrous histiocytoma were fibroblast-like, histiocyte-like, intermediate (fibrohistiocytoid) and undifferentiated cell. There were cells bearing variable stages of differentiation along the fibroblastic and histiocytic lines from undifferentiated cells. 2. There was no difference in cellular composition ultrastructurally between storiform-pleomorphic, myxoid and inflammatory subtypes. 3. Junctional complexes were shown in fibroblast-like, histiocyte-like cells, intermediate cell and myofibroblasts. Long desmosomes were observed in histiocyte-like cells, intermediated cells and myofibroblasts, Paired subplasmalemmal densities were also shown in fibroblast-like cells and. intermediate forms. 4. Immunohistochemical reactions revealed strong staining reactions for α1-antitrymotrypsin in histiocyte=like cells and multmucleated giant cells. Vimentin was reactive for fibroblast-like cells, histsiocyte-like cells and multinucleated giant cells. However, no evidence of staining reactions for α1-antitrypsin, a1-antichymotrypsin, vimentin, lysozyme in the cells of early stage of differentiation along the fibroblast and histiocyte-like cells from the undifferentiated cells. 5. In conclusion it is suggested that malignant fibrous histiocytoma may be considered a primitive mesenchymal tumors originating from undifferentiated cells.

C₄유분을 이용한 옥텐류의 합성에 있어서 1,3-Butadiene의 함량에 따른 이량화 촉매의 수명에 관한 연구

전종기,한원희,조정호,고승태,노상균 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

Selective hydrogenation of 1,3-butadiene in C4 raffinate was carried out in fixed bed reactor using Pd/a1unina catalysts, Concentration of 1,3-butadiene in C4 raffinate could be reduced under 100 ppm.The life of dimerization catalyst using C4 raffinate after selective hydrogenation was longer than that of dimerization catalyst without selective hydrogenation.It was found that dilution of olefin concentration in feed was effective to increase dimerization catalyst life.

직장암에서 자율신경보존술후 배뇨기능의 변화에 대한 요역동학적 연구

조원상,이상전,송영진 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.4

생쥐 중이와 상기도 점막의 섬모세포운동

정하원,오승하,유원석,이강수,모지훈,전상준,김인상,김종선 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.9

냉각면이 있는 정방형내 이종유체의 저온거동에 관한 실험적 연구

전승배,장원택,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

Two stratified fluids (water and spindle oil) in aspect ratio of 1 to 1 were studied experimentally with the variation of an initial temperature and a cooling surface temperature in the square cavity with a lower cooling surface. With the initial temperature being varied, a cooling surface temperature were varied. With supercooling phenomenon being processed, a latent heat was emitted. The temperature of the spindle oil was increased with the occurrence of the latent heat. In case of initial temperature was low. the supercooling phenomena were observed and continued up to the end of experimental.

한국형 우울장애 약물치료 알고리듬 (Ⅳ) : 우울장애의 아형 및 부작용에 따른 항우울제의 선택과 여성우울장애에서의 치료전략

전현태,이상열,김원,민경준,박원명,서정석,석정호,송해철,전덕인,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : In 2002, the Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) was published, but there has been a need for a guideline about detailed issues of depressive disorder. We revised KMAP-MDD andreestablished Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. Methods : A questionnaire had been developed by the executive committee for KMAP-DD. The review committee consisted of 101 experienced psychiatrists. From the total of 22 questions in the questionnaire, 7 questions were evaluated for these subjects . We classified the expert opinions to 3 categories according to its confidence interval; first, second and third line. Results : SSRI and venlafaxine were the first line antidepressants (AD) for atypical and melancholic depression. For dysthymic disorder and minor depressive disorder, SSRI was recommended as the first line medications. Only AD medications was a preferred initial strategy for treating premenstrual dysphoric disorder, mild to moderate and severe non-psychotic postpartum depression. In severe psychotic postpartum depression, combination therapy of AD and atypical antipsychotics was the treatment of choice. SSRI was preferred when considering sedation, anticholinergic and cardiovascular adverse effects. Also, experts recommended mirtazapine against gastrointestinal adverse effects and bupropion in avoiding sexual dysfunction. Conclusion : These results suggest that clinicians have to consider both clinical situations and drug adverse effects in the choice of antidepressant medications.

輻射난방공간의 熱環境 特性에 따른 老人의 主觀的 反應評價에 關한 硏究

전규엽,이상홍,홍원화 대한건축학회 2003 대한건축학회논문집 Vol.19 No.6

This study aims to present the basic data for the establishment of indoor optimal thermal environment in housing for the aged by through field and subject response survey and experiment in model living room. As the first pace of study, the thermal-environment factors were defined by the measurement of physical thermal environment element (dry bulb temperature, radiative temperature, relative humidity, and air velocity) and the environmental needs of the residents was investigated through the questionary survey of the response to thermal environment in welfare facility with radiation heating for the aged in Teagu during winter in 2001. As a result of it, a model living room was designed and structured as a actual domestic room. Physical thermal-environment factors and environmental needs of the occupants in radiative heating space were examined thoroughly by measuring physical thermal environment element and investigating subjective response according to varied condition. The result of study can be summarized as follows; The value of the floor temperature in model living room was 30~34℃ according to temperature control of a constant temperature water tank. In particular, the value of the floor temperature was 33~34℃ and air temperature was 27~28℃ when the constant temperature water tank was 70~80℃. At this point, the value(38~42%) of indoor relative humidity was in the standard(37~48%) of relative humidity comfort. And also, occupants felt somewhat warm at the body on the whole as well as at the lower part of the body. However, the response of occupants was uncomfortable comparatively at the upper part of the body. The reason of that was seemed to be lack of ventilation and stifling atmosphere of the spot.

汗出의 病因病機에 對한 文獻的 小考

田炳薰,陸相元,李光揆 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.2

땀이란 人體內에서 體溫을 調節하고 老廢物을 排泄하는 등의 중요한 生理作用을 한다고 알려져있다. 韓醫學에서는 津液의 一種이라하여 汗出에 대한 警覺心을 强調하기도 하였으며 發汗法에 대한 重要性과 이것으로 因한 後遺症을 警告하기도 하였다. 이에 筆者는 正常的인 新陳代謝로서의 땀이 生理機能失調로 인한 非正常的인 땀이나 汗蒸 혹 찜질방 등의 人爲的인 發汗으로 인한 땀과는 本質的으로 差異點이 있을 것으로 思料되어 땀에 대한 여러 가지 文獻을 整理하여 발표하고자 한다. It is known sweat plays important roles in temperature regulation and secretion as phtsical action. In oriental medicine, it is regarded as a kind of dody fluids, and the importance and the side effects of excessive eprspiration were emphasized. The objective of this study is to investigate literature and introduce the results because there will be the difference between the usual sweat for metastasis and the extraordinary sweats by failure of physical funciton, sauna and other artificial perspiration. The results of this study are summarized as follows: 1. Swteat is a kind of body fluid and the sweat for physical is considered to be made up of water component and made by the weakness of defensive energy of lung. 2. The function of activity of gi by triple heater brings about the thin and clear fluid and the fluid is made by the opening and closing function of defensive energy. 3. The disorder of opening and closing function comes about sponataneous perspiration and night sweats, spontaneous perspiration is divided into disharmony between Ying and Wei, insufficiency of both the spleen and the lung of gi and so on, and night sweats is divided into deficiency of the heart blood and deficiency of Yin brings about interior heat-syndrome. 4. Swear is named variously. 1) By the time and feeling : spontaneous perspiration, night sweats. 2) By the perts of body : perspiration on the forehead, chest, nose, groin, hand and foot and so forth. 3) By the color : yellow, red, green sweat. 4) By the condition : perspiration after shivering, hot and cold sweats and so on.