Three-Year Surveillance (2016-2018) of Chigger Mites Vector for Tsutsugamushi Disease in the Hwaseong-Si Area of Gyeonggi-Do, Republic of Korea

전호종,Seung Jegal,Myung-Deok Kim-Jeon,Jong Yul Roh,Wook-Gyo LEE,Seo Hye Park,Seong Kyu Ahn,Jinyoung LEE,Young Woo GONG,Mun Ju Kwon,박영일,Tong-Soo Kim 한국곤충학회 2020 Entomological Research Vol.50 No.2

Owing to climate change, the global resurgence of vector-borne infectious diseases has emerged as a critical public health issue. Orientia tsutsugamushi is the etiological agent of tsutsugamushi disease (scrub typhus) a mite-borne acute febrile disease occurring in the Asia-Pacific region. We investigated the prevalence of tsutsugamushi disease transmitted by chigger mite vectors living on rodents. Using sticky-type chigger traps for three months during 2016–2018, 1,057 chigger mites were collected (chigger mite index, 1.31) from four locations in the Hwaseong-si area of Gyeonggi-do, Republic of Korea. Five species distributed among three genera were identified. In addition, 94 rodents were captured (collection rate: 7.83%) using Sherman live traps over the course of three months (April, October, and November) during 2016–2017. Three rodent species were captured and identified and the striped field mouse (Apodemus agrarius) was the dominant rodent host species in the surveyed area. A total of 10,469 ectoparasitic chigger mites were recovered from the 94 rodents, from which 13 species distributed among four genera were identified. Of the 5,250 chigger mites examined, Leptotrombidium pallidum was most abundant (n = 2,558), followed by L. orientale, L. scutellare, L. zetum, Euschoengastia koreaensis, L. subintermedium, and Neotrombicula tamiyai. Of the examined chigger mites, no groups recovered from rodent hosts tested positive for O. tsutsugamushi. This study provides fundamental regional information on vector-borne disease data collection in the Hwaseong-si area, Gyeonggi-do, and will further contribute to formulating disease control and prevention strategies.

先天性 急性 骨髓性 白血病 : Mongoloid 新生兒에 隨伴된 1例報告 Report of a case in a Mongoloid neonate

田浩淙,李明姬,徐在烘,朴榮珍 朝鮮大學校 醫學硏究所 1982 The Medical Journal of Chosun University Vol.7 No.-

Congenital leukemia is very rare neoplasm, etiology of which is unknown. It reveals very short courses of clinical process and results in abrupt death, and the congenital leukemia is very difficult to manage. However, congenital leukemia is a very interested material and may be contributed to the cytogenesis for explain the relaticnship between intrauterine environments and genetic background. The significant findings of congenital leukemia are erythropenia, thrombocytopenia and leucocytosis due to replacement of bone marrow by leukemic cells and enlargement of lymph node and hepatosplenomegaly with infiltration of leukemic cells in those organs of tissue. Congenital leukemia must be distinguished from sepsis, erythroblastosis fetalis, toxoplasmosis and syphilis. A congenital acute myeloblastic leukemia in a 5-day-old mongoloid male with a chief complaint of poor sucking power for I day before admission to Chosun University Hospital on the 5th, September, 1980 was presented. The neonate was apparently well until 3rd day of life when he suffered from symptoms of poor sucking power and had icteric appearance of the whole body, circumoral cyanosis and abdominal palpable mass. At this time, total white blood cells count was markedly elevated, 320,000 per cu. mm and almost all the nucleated cells are myeloblasts with negative peroxidase reaction. The case of congenital acute myeloblastic leukemia associated with mongolism were discussed with brief literature review.

DMN과 GALN에 의한 간세포손상이 신사구체의 면역글로부린 침착에 미치는 영향에 관한 실험적 연구

전호종,설주문,김수홍 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Glomerular IgA deposition often occured in prolonged hepatobiliary disease and also it's definite pathogenesis is not yet cleared, In the present study, liver injury was induced by intraperitoneal administration of single dose of dimethylnitrosamine and D-galactosamine in rats to investigate the pathogenesis of glomerular Ig A deposition by observations of immunohistochemical and special stains. The results obtained were as follows 1. In the dimethylnitrosamine-treated rats, there were extensive blood-filled necrotic spaces containing debris of necrotic hepatocytes and sinusoidal lining cells in the centrilobular areas 5 days after intraperitoneal administration. 2. In the D-galactosamine treated rats, spotty necrosis with inflammatory cell infiltration throughout the lobule, and swelling and increment of Kupffer cells were appeared 2 days after intraperitoneal administration. 3. There were slightly increased thickness of renal glomerular basement membrane and widening of the mesangeal matrix in dimethylnitrosamine-treated rats, 14 days after intraperitoneal administration, but no pathological changes were observed in glomerular basement membrane and mesangeal cells in D-galactosamine treated rats. 4. There were glomerular IgA deposition after a single dose administration of dimethylnitrosamine. Slight deposits of IgA appeared 2 days after administration, In 5 days after administration, the deposits gradually intensified and peaked at 14 days after administration, However in the D-galactosamine-treated rats, only slight deposits of IgA appeared at days 7 and 14 There were no depositions of IgG in the dimethylnitrosamine and D-galactosamine treated rats. 5. These results suggest that dysfunction of the hepatocytes and Kupffer cells contribute to glomerular IgA deposition.

악성 섬유성 조직구종의 기원에 관한 면역조직화학적 및 초미세형태학적 연구

전호종,임성철,강종식,김일,황호원 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.15 No.1

Malignant fibrous histiocytoma(MFH) was first terminologically introduced in 1963 to refer to a group malignant soft tissue tumors characterized by a stonform growth pattern and these tumors are a oup of sarcomas composed of cells morphologically resembling fibroblast and histiocvte. The histogeisis of MFH is still controversial, but a more complete appreciation of it's morphogenesis has been ovided by tissue culture and ultrastructural studies. In the present study, ultrastructural and immunohistochemical studies of seven cases of MFH disclosee maturation and development of principal types of cells constituting MFH and immunohistochemical actions to investigate the histogenesis of malignant fibrous histiocytoma. The results obtained were as follows. Malignant fibrous histiocytoma composed of different portions of fibroblast-like cells, histiocyte-like cells, cells intermediate between histiocyte-and fibroblast-like cells, multinucleated giant cells, undif ferentiated cells, xanthomatous cells and myofibroblast. The principal cell types of malignant fibrous histiocytoma were fibroblast-like, histiocyte-like, intermediate (fibrohistiocytoid) and undifferentiated cell. There were cells bearing variable stages of differentiation along the fibroblastic and histiocytic lines from undifferentiated cells. 2. There was no difference in cellular composition ultrastructurally between storiform-pleomorphic, myxoid and inflammatory subtypes. 3. Junctional complexes were shown in fibroblast-like, histiocyte-like cells, intermediate cell and myofibroblasts. Long desmosomes were observed in histiocyte-like cells, intermediated cells and myofibroblasts, Paired subplasmalemmal densities were also shown in fibroblast-like cells and. intermediate forms. 4. Immunohistochemical reactions revealed strong staining reactions for α1-antitrymotrypsin in histiocyte=like cells and multmucleated giant cells. Vimentin was reactive for fibroblast-like cells, histsiocyte-like cells and multinucleated giant cells. However, no evidence of staining reactions for α1-antitrypsin, a1-antichymotrypsin, vimentin, lysozyme in the cells of early stage of differentiation along the fibroblast and histiocyte-like cells from the undifferentiated cells. 5. In conclusion it is suggested that malignant fibrous histiocytoma may be considered a primitive mesenchymal tumors originating from undifferentiated cells.

소동맥 및 세동맥의 내막초자화에 관한 병리조직학적 연구

전호종 中央醫學社 1981 中央醫學 Vol.41 No.3

Southern Blot Hybridization법을 이용한 악성 림프종의 면역유전형에 관한 연구

전호종,기근홍,김윤신,이미숙,이미자,장원재,장숙진,박영진,정춘해,정종훈,양성훈,이광민 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Immunogenotyping using gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant Iymphoid neoplasms. The lineage and clonality of the malignant Iymphoid neoplasms can be identified by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin and T-cell receptor genes. The analysis of the gene rearrangements on the malignant Iymphoid neoplasms are also useful as a sensitive unique clonal markers to detect early recurrence in patients with malignant Iymphoid neoplasms after treatment. To analyze the sensitivity and specificity of gene rearrangements in the diagnosis of malignant Iymphoid neoplasms. 24 cases of malignat Iymphoma were examined by Southern blot hybridization using CTβ-T cell receptor β chain gene-DNA probe and JH-immunoglobulin heavy chain gene-DNA probe. The results of the immunogenotypings using Southern blot hybridization disclosed high correlation between the immunophenotyping using immunohistochemical stain with monoclonal antibodies (B-cell Iymphoma 84.2%. T-cell Iymphoma 75% ). The analysis of the gene rearrangement of the angioimmunoblastic lymphadenopathy(AILD) and unclassifiable Iymphoma using immunohistochemical stain could resolve the monoclonality and lineage . Rearranged bands to the CTβDNA probe were observed in one case out of 2 cases of AILD. One case of unclassifiable Iymphoma showed rearranged bands to the CTβ DNA probe. There were no rearrangements in reactive follicular Iymphoid hyperplasia and paracortical Iymphoid hyperplasia. In conclusion, DNA gene rearrangement study should be applied to differentiate the clonality and cell lineage in the malignant Iymphoma with indistinctive immunophenotype.

간에서 발생한 Kupffer 세포 육종-1예 보고-

전호종,기근흥,서재홍,임성철,송혜숙 대한병리학회 1989 Journal of Pathology and Translational Medicine Vol.23 No.1

횡문근 육종 14례에 대한 병리조직학적 연구

전호종,기근홍,서재홍,송혜숙,지제근 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1

횡문근 육종은 소아나 유아에서 제일 흔히 관찰되는 육종이고 또한 성인에 있어서도 그 발생 빈도가 비교적 흔한 종양으로 신체 어느부위에서도 발생하는 종양으로 알려져 있다. 최근에 이들 종양에 대한 광범위한 연구, 특히 병리 조직학적 형태와 임상적 연구 및 치료에 관한 집중적인 연구 결과는 진단에서 부터 완치 까지 놀라운 진보를 가져왔다. 저자들은 서울대학교 의과대학 병리학 교실에서 횡문근 육종으로 진단된 13례와 조선대학교 외과대학 병리학 교실에시 진단된 1례를 포함한 총 14례의 횡문근 육종에 대한 자료검색을 통하여 다음과 같은 걸론을 얻었다. 1. 환자의 연령은 9개월에서 70세까지의 다양한 분포를 보여주었으며 평균 연령은 19.9세 이었다. 남녀 비율은 남자 9례, 여자 5례로(1.8:1) 남자가 많았다. 2. 종양이 발생하는 부위는 매우 다양하였다. 특히 생식 비뇨계에서 많이 밭생하였는데 우측 고환 3례, 전립선을 침범한 방광이 2례, 자궁경부 1례 이었고 두경부 에서는 좌비공 1례, 좌비 인강 1례, 우측귀 1례, 우측안검 1례, 연구개 1례, 우측상악동 1례, 후복벽 1례, 우측하지 1례 이었다. 3. 조직학적 형태는 botryoid형이 4례 (28.5%)이며 이는 주로 연구개, 우측안검, 우측귀, 좌비공에서 발생하였고 주로 소아에서 많이 발생하였다(평균 16.5세). 암전이는 4례중 3례에서 관찰 되었다. Embryonal형은 6례로서 생식비뇨 기계에서 많치 발생하였는데 우측고한 3례, 전립선을 침범한 방광기 1례, 쟈궁경부 1례, 좌비인강 1례로 42.8%를 차지하였으며 평균 연령은 26.8세 이었다. 암전이는 6례중 2례에서 관찰되었다. Alveolar형은 방광 1례, 후두벽 1례등 총 2례로 14.2% 였으며, 암전이는 없었다. Pleomorphic 형은 우측하지 1례, 우 상악동에서 1례로 총 2례이었으며 평균 연령은 13.5세이었고 암전이는 2례중 1례에서 관찰되었다. 4. 증상은 종양이 발생하는 위치에 따라서 다양한 증상을 보여주었는데 특히 종양이 급격히 성장하기 때문에 소위 masse effect등이 관찰되었다. 5. 종양이 발생하는 장소와 조직학적 형태에 따르는 Group 결정과 Stage 결정은 IRS(Intergroup Childhood Rhabdomyosarcoma Study)기준을 따랐으며 수술시 소견과 전이여부 그리고 병리 조직학적 소견에 근거 하였다. Embryonal 형중 방광에서 발생한 형의 Group은 IV, 우측고환 IV, 우측고환 I, 좌비인강 IV, 이었고 Pleomorphic 형중, 우측하지에서 발생한 육종의 Group은 IV, 우상악동은 Ia이었다. Botryoid 형은 좌비강에서 발생한 육종의 Group 은 II, 우안검은 IV 우측귀는 III, 연구개는 Group I이었다. Alveolar 형은 방광에서 발생한 육종의 Group은 Ia, 후복벽은 Group Ia이었다. 6. 임파절 전이나 주위 조직으로 종양침윤이 관찰된 예는 총 14례중 7례 이었고 전이가 안된 예는 5례, 확인되지 않는 예가 2례이었다.

Faulkner와 기계화 사회 -개(個)와 조직의 상극과 화해

전호종 서울대학교 미국학연구소 1982 미국학 Vol.5 No.-

黑人 文學論

田浩鍾 全北大學校 1973 論文集 Vol.15 No.-

Ralph Ellison이나 James Baldwin의 작품을 읽으면 그들이 흑인이라는 문제에서 사고하면서도, 동시에 혈형적인 현대인으로서 사고하는 그 예지와 정감에 놀라지 않을 수 없다 더욱이 그러한 예지와 정감은 그들이 끈덕지게 걸머진 대의 역사의 밑받침을 받고 있는 점에서 우리는 거기에 일종의 에언적인 것 조차 느끼게 된다.