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최강원 대한에이즈예방협회 2004 레드리본 Vol.61 No.-
1999년 7월부터 2003년 9월까지 4년 동안에 서울대학교 병원에 내원한 HIV 감염자 중에서 매독에 걸린 환자가 없었다. 그러나, 2002년 상반기부터 1기 및 2기 매독에 걸린 사람은 급증하였고, 2003년 하반기에는 연 100명 당 18명 꼴로 매독 환자가 급격히 증가하였다.
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최강원,장우영,이종욱,김수정,Choi, Gang-Won,Jang, Woo-Yeong,Lee, Jong-Wook,Kim, Su-Jung 한국미생물학회 2010 미생물학회지 Vol.46 No.2
Disposable contact lenses, which are one type of soft contact lenses, provide convenience in use, but also cause various ocular infectious diseases. Microorganisms that cause eye diseases include Acanthamoeba, bacteria, Fungi, and so on. It is impossible to prevent microorganism contamination completely due to the use of hands as wearing contact lenses. The contamination by various microorganisms leads to infectious keratitis, but it is not well known for the exact microorganisms that affect the disease. For this reason, to identify the microorganisms, two groups that are commonly used for disinfection of lenses were divided: normal saline solution and multiple purpose solution. Using these solutions the degree of microorganism contamination was observed according to the days of 1, 3, 5, 10, and 15. Twenty students by two groups from Ophthalmic Optics department at D college in Daegu Metropolitan city participated in the experiment after their ocular health conditions were checked. During they wore one-day disposable lenses for 1, 3, 5, 10, and 15 days, bacteria were cultured in media. The results, which were Gram stained by selecting the cultured colonies, show as followings: Gram positive cocci 33%, Gram-negative cocci 2%, Gram positive bacilli 34%, and the Gram negative bacilli 31%, respectively. As for the identification of potential pathogens, VITEK system and API kit methods were used. Keratitis caused by bacteria known as Staphylococcus aureus, Pseudomonas aeruginosa were detected as a result of wearing contact lenses. This study examined the distribution of bacteria as wearing one-day disposable contact lenses and pathogenic bacteria according to the duration of wearing them. In conclusion, the importance of hygiene when using contact lenses is suggested.
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최강원,배현주,김양수,김성민,박선양,김병국,김노경,우준희 대한화학요법학회 1990 대한화학요법학회지 Vol.8 No.1
In a randomized, prospective study, ceftazidime monotherapy was compared with a combination of piperacillin and tobramycin for the treatment of infection in febrile granulocyto penic cancer patients. The subjects consisted of 40 patients with acute leukemia or solid tumor who developed fever and other signs of infections after induction chemotherapy or bone marrow transplantation. 21 patients were randomized to the piperacillin plus tobramycin combination, while 19 patients were allocated to ceftazidime monotherapy. Initial granulocyte count, duratation of granulocytopenia, infection days and granulocyte count on therapeutic responsewere all comparable in both treatment groups. On 72 hour assessment, success (with or with-out modification) rate according to NCI criteria was 100% in ceftazidime and 95% in combination group. Success according to EORTC criteria was 26% and 48% respectively. On posttreatment assessment, success rate according to MCI criteria was 91% in ceftazidime group and 70% in combination group, while one according to EORTC was 33% and 40% respectively. There was no statistical significance between the two success rates. The superinfection was more commonly seen in the combination group, esp. by resistant E. coli, even though the difference was not significant.
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제 15차 세계 에이즈 회의 -학술대회가 아닌 '정치대회'로 변질-
최강원 대한에이즈예방협회 2004 레드리본 Vol.60 No.-
전 세계의 이목이 집중된 가운데 지난 7월 $11\~16$일 태국 방콕에서 제 15차 세계 에이즈 회의(International AIDS Conference)가 열렸다. 2년 전에 바르셀로나에서 열렸던 14차 회의에 참석하지 못하여, 그 간 에이즈 관련 연구에 어떤 변화와 발전이 있었는지도 보고, 사람들도 만나볼 겸 방콕행 비행기에 몸을 실었다.
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