민간공원 특례사업으로 인한 청주시 공원 · 녹지의 연결성 변화 분석

이종욱(Lee, Jong-Wook),박종광(Park, Jong-Kwang),홍성조(Hong, Sungjo) 대한건축학회 2022 대한건축학회논문집 Vol.38 No.1

The Korean government introduced a private-initiative park project to prevent further environmental damage caused by the abolition of parks. The private-initiative park project is expected to affect the connectivity of the green space system by creating a part of the park site as a non-park facility. The purpose of this study is to analyze the change in the connectivity of the green space system in relation to the private-initiative park project. The spatial scope of this study is in Cheongju, Korea. There were 8 private-initiative park projects selected as research subjects. The IIC indicator and d_IIC indicator, which are widely used in the analysis of green space connectivity, were used as analysis methods. Changes in connectivity according to four scenarios were simulated. Upon analysis, the results revealed that private-initiative park projects can reduce the overall connectivity of green spaces. The connectivity of private-initiative park projects can be improved compared to the situation of unplanned development while maintaining the current state. Lastly, changes in connectivity due to private-initiative park projects vary by region. This study was meaningful as an early study that analyzed private-initiative park projects in terms of the connectivity of green areas and is expected to be used for the improvement of the park and green space system in the future.

차량 재도색용 청색 페인트의 분석

박성우,손성건,박하선,박성지,정영호,홍성욱,박종신 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

흰쥐 시상에서 Epidermal growth factor receptor면역반응 신경세포의 생후 발달에 관한 연구

박영란,정윤영,김종중,문정석,오재욱,정영욱,김주수 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : Epidermal growth factor receptor (EGFR), a 170-kDa transmembrane glycoprotein, appears to mediate epidermal growth factor (EGF) activity. Transforming growth factor-α and EGF produce their biological effects in numerous systems by stimulating the EGFR In this study, we examine the postnatal development of EGFR immunoreactivity in the different regions of the thalamus of the rat Materials and Methods : The present study is based on 28 postnatal cases of rat thalamus ranging from the day of birth, postnatal day 0 (P0) to 30 days (P3, P5, P10, P15, P20, P30), and these cases were compared with adult rat thalamus. Cryostat sections were processed free-floating with monoclonal antibody by immunohistochemistry Results : EGFR immunoreactivity in the thalamus of the rat showed very different patterns according to postnatal ages and thalamic areas. EGFR-immunoreactive cells appeared in the first two postnatal weeks, except the ventral posterior thalamic nuclei. In the early postnatal days, EGFR-immunoreactive cells appeared thalamic midline structures, increased progressively in the first two postnatal weeks, and followed mediolateral gradient. The mature patterns of EGFR-immunoreactive cells were achieved at P20 Conclusion : These data indicate that the maturation of EGFR-immunoreactive cells requires a relatively prolonged period of time to achieve an adult configuration. Many growth factors probably play protective or neurotrophic roles at EGFR-immunoreactive neurons of thalamus both young and adult rats In addition to difference in time of appearance in thalamic nuclei and developing pattern with mediolateral gradient suggest that EGFR-immunoreactivities are correlated with the appearance of the related functional.

천연두 백신 접종 후 발생된 급성 심근염 1예

박옥성,김종환,이광욱,윤성훈,강동구,이승욱,조상기 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Acute myocarditis complicating coronary vasospasm after smallpox vaccination is very rare complication that can be generally developed within less than 30 days after vaccination. Clinically and biochemically, this disorder is often mimic and highly suggestive of acute myocardial infarction. We report 21 years old man that had a history of a smallpox vaccination 3 weeks ago and prodromal symptoms(fever, malaise etc) a few days ago. hIe visited to our hospital because of abrupt onset of severe substernal chest pain, dyspnea and diaphoresis. At admission, electrocardiography was ST elevation in lead Ⅰ, aVL, V4, V5, and V6. The CK-MB level was 68 U/L, LDH level was 760 U/L, Troponin-Ⅰ was 24.64 ng/㎖, and Troponin-T was positive. 2D-echocardiograpy was normal left ventricular function, Clinically we presumed this disorder as acute myocardial infarction and we promptly performed the coronary angiography and revealed focal spasm in distal left coronary artery territory without critical stenosis in both coronary arteries. We diagnosed this disorder as coronary vasospam complicating acute myocarditis that is different with acute myocardial infarction, and we prescribed nitroglycerin and nifedipine. After discharge, he is now well without any symptoms and has been following up monthly at our outward department for 6 months.

돼지의 골기질유도 골형성단백질의 골유도능에 관한 실험적 연구

박영욱,김수경,이종호 大韓顎顔面成形再建外科學會 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.3

Bone morphogenetic proteins (BMPs) are a group of transforming growth factor beta(TGF-β)-related factors and multifunctional proteins , especially the only known biologic factors capable of inducing endochondral bone formation at an extraskeletal site. This study was performed to investigate the effect of the partially purified porcine BMP(pBMP) at an ectopic site. PBMP was partially purified from porcine bone matrix and its activity was monitored by an in vivo bioassay. The purification method utilized extraction of the bone-inducing activity with 4M guanidine, followed by chromatography on heparin-Sepharose. Active fractions were assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. And the fractions were reconstituted with inactive insoluble collagenous bone matrix from rats, acid soluble type I collagen from rat tail and chondroitin-6-sulfate sodium salt and implanted into the pectroralis muscle pouches of Sprague-Dawley rats. And the carrier complex was implanted on the opposite side as control. The rats were sacrificed at the day of 1st, 3rd, 5th, 7th, 11th, 14th and 21st after implantation and examined histologically, radiologically and biochemically. And alkaline phosphatase activity and calcium content were used as indices of bone formation. The results were as follows; 1. Active fractions were localized in a zone between 31 and 40 KDa on SDS-PAGE. 2. The implanted 3.0㎎ of the partially purified pBMP induced cartilage and bone in the muscle tissue of rats through an endochondral ossification process. 3. Inactive insoluble bone matrix, type I collagen and chondroitin-6-sulfate have functioned as carriers for pBMP, but revealed some foreign body reactions. 4. Soft X-ray didn't reveal significant change between the experimental and the control group. 5. The alkaline phosphatase activities in the experimental group of 5th, 7th, 11th, 14th and 21st were increased significantly compared with control (p<0.01) with the peak in the group of 11th day. 6. With time, the calcium content of the experimental group increased. And the calcium contents in the experimental group of 11th, 14th and 21st were increased significantly compared with control (p<0.01).

강진만에서 미생물의 년 변화

박종천,오재영,정용욱,주현수,이원교,유춘만,이우범 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-

The biological surveys were performed at seven sites in the Gangjin bay from February, 1998 to November, 2001. In order to analysis of environmental variation, numbers of heterotrophic bacteria, general fungus and fecal coliforms were enumerated in each sample. The result showed that variation range of heterotrophic bacteria, general fungus, and fecal coliforms were 2.9 x 10^(3)~9.6 x 10^(3) CFU/ml, 17.2~80.1 CFU/ml, and 6.3~682.5 CFU/100ml for four tears(1988~2001), respectively. Density of heterotrophic bacteria and general fungus were gradually decreased for four tours, while fecal coliforms were suddenly increased. Specially, numbers of fecal colifoms were increased the more 100 times in 2001 than that 1998. We think that it was probably caused a little rainfall in February, 2001. There result suggests that ecosystem of Gangjin bay were mainly regulated by 2~3 factors, which were inflow of fresh water, salinity and variation of water temperature.

주민등록제도 및 주민등록정보활용에 대한 연구 : 개인정보프라이버시 권리 확보를 중심으로

박홍윤,변종화,임동욱 忠州大學校 2003 한국교통대학교 논문집 Vol.38 No.1

To be progressed in information society, personal information protection is one of the most important things for desirable development of information society. This research investigates personal information infringements and effective protection means in resident registration system and use of resident registration information. First, this research is studied the history of Resident Registration Law(Korea ID law) and need of positive privacy by computer technology improvement, Second, this research evaluated the resident registration system on OECD's privacy protection principles: Collection Limitation, Data Quality, Purpose Specification, Use Limitation, Security Safeguards, Openness, Participation and Accountability. In conclusion, From the previous analysis and normative protection principles, the following alternatives are presented for the privacy protection a. use limitation of resident registration number and revision of the resident registration number system. b. establishment of personal information protective organization which can independently determine personal information protective action and policy. c. government faith restoration to the resident registration system

양성중력가속도가 조종사의 심방이뇨 호르몬(Artrial Natriuretic peptide)에 미치는 영향

박종관,서만옥,설경환,조경우,박병옥 공군본부 의무감실 1991 항공의학 Vol.39 No.1-2