자연산 점몰개, Squalidus multimaculatus Hosoya et Jeon의 새인두흡충, Clinostomum complanatum (Rudolphi, 1814) 감염

박명애 ( Myoung Ae Park ),서정수 ( Jung Soo Seo ),정승희 ( Sung Hee Jung ),최희정 ( Hee Jung Choi ),전은지 ( Eun Ji Jeon ),지보영 ( Bo Young Jee ),이완옥 ( Wan-ok Lee ),우승호 ( Sung Ho Woo ),이은혜 ( Eun Hye Lee ) 한국어병학회 2011 한국어병학회지 Vol.24 No.2

경상북도 영덕군의 하천에 서식하는 점몰개 spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon)의 근육에서 새인두흡충 Clinostomum complanatum (Rudolphi, 1814)의 피낭유충이 발견되었다. 감염된 점몰개는 "yellow grub"인 기생충의 피낭유충으로 인해 표면이 울퉁불퉁하게 보였으며, 수면위에 힘없이 유영하였고 일부 폐사한 개체도 발견되었다. 분리된 탈낭유충의 형태는 혓바닥 모양이었으며, 크기는 2.85~5.89 mm×0.8~1.99 mm였다. 어체당 1~98 개의 피낭유충을 분리하였으며 평균 감염수는 25개로 나타났다. 특히, 성어크기인 평균 7 cm 정도의 점몰개는 100% 감염되어 있었다. 본 연구는 한국의 자연수계에 서식하는 어류에서 C. complanatum 의해 질병이 발생하고 폐사가 일어난 첫 보고이다. The metacercariae of Clinostomum complanatum (Rudolphi, 1814) were isolated in the whole body muscle of wild freshwater fish, spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon) from the local river in Yeongdeok, Gyeongsangbuk-do, Korea. The infected fish with bumpy body surface by "yellow grub" showed erratic swimming behavior and some fish were died. The isolated excysted metacercariae were tongue shaped and 2.85~5.89 mm × 0.8~1.99 mm in size. 1~98 metacercariae were isolated in individual fish and mean infection intensity was 25. All examined adult spotted barbel gudgeon sizing 7 cm in body length were infected. This is the first report of disease outbreak and mortality caused by C. complanatum infection in wild freshwater fish in Korea.

Cyclosporin 함유제제의 생물학적 동등성 시험

박은전,손영택,손동환,고건일,김재백 圓光大學校 藥品硏究所 1995 藥品硏究所報 Vol.10 No.1

非同期 傳達모드 通信網을 위한 影像 트래픽의 特性化에 대한 硏究

全龍熙,朴貞淑,朴銀美 대구효성가톨릭대학교 응용과학연구소 1995 응용과학연구논문집 Vol.4 No.-

Asynchronous Transfer Mode(ATM) has been proposed as the target switching and multi-plexing schemes for broadband ISDN(B-ISDN). A variety of traffic types such as voice, data and video can be integrated into the network. Among the traffic types, video requires a significantly higher bandwidth than voice and data. Since video will be a major traffic component in the future multimedia communiation, transporting video traffic in a very efficient manner will be the key point for the successful implementation of B-ISDN. Therefore, the characterization of video traffic sources are essential for the design of traffic control algorithms in ATM networks. The knowledge of bit rate statistics are necessary for the proper bandwidth allocation algorithms in the ATM networks. Since VBR(Variable Bit Rate) video transmission can be achieved taking advantages of the inherent burstiness of video sources, VBR encoding algorithms are well suited for the ATM networks. VBR video transmission also provides uniform quality video by transmitting at a higher rate during high-activity scenes and at a low rate when there is less motion. As the bit rate is not a constant, it is necessary to develop some statistical models in order to represent cell arrivals from video sources. The bit rate generated by a VBR coder depends on the type of video scenes, video coding algorithms, and video quality requirements. A video source model should have simple and effective parameters for performance evaluation and traffic control of ATM networks. In this paper, some video models are surveyed and reviewed. A video model was chosen and simulated. The simulation results are shown in order to illustrate some generated bit pattern of video sequence. Some of the results found may also be used for the design of efficient traffic control algorithm in ATM networks.

인장물성 평가를 위한 연속압입시험법의 실험조건 최적화

전은채,박주승,권동일 대한금속재료학회 2002 대한금속·재료학회지 Vol.41 No.2

The continuous indentation test, which measures indentation depth with applied load, has been used to evaluate the tensile properties whose accuracy can vary depending on such experimental conditions as maximum depth ratio, indenter radius, number of unloadings and unloading ratio. In this study, Taguchi method, one of the designs of experiment, was applied to quantify the effects of the experimental conditions effectively. Using a signal-to-noise ratio calculated from the error in the indentation tensile properties, the optimum values of the experimental conditions were presented. The indentation tensile properties from the load-depth curves with the optimum conditions showed better accuracy than those with existing conditions.

기능성 생식, 다이어트식 및 장개선제가 비만개선에 미치는 영향

전태일,전은자,김창성,이주용,안홍석,임병우,최영숙,박웅채,박동기 建國大學校附設農業資源開發硏究所 2001 農資源開發論集 Vol.23 No.-

Obesity is defined as an excess of body fat and is closely related to diabetes, hypertension and heart disease. Dietary cure has been paid attention as a method for preventing from or curing obesity. The effect of some food products developed in this laboratory, such as, functional saengsik (Health & Joy saengsik), diet food (Health & Joy diet meal) and intestine function activator (Cell-pa, commercial name) on curing and protecting from obesity were investigated. Diet program was applied to 31 adults (Males 22, Females 9) with above 120% body mass index (BMI). After diet program was applied, body weight, body fat and fat weight decreased by 1, 4.8 and 4.5% (p<0.01), HDL-cholesterol increased by 3.6% and LDL-cholesterol and atherogenic index decreased by 6.6 and 7.7% (p<0.05). Consequently, the food products developed in this laboratory effectively reduced the obesity.

심실전도장애환자에서 위상각 분석의 의의

전은석,곽병수,이강욱,박종훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

It is known that the normal His-Purkinje system provides for nearly synchronous activation of the right and left ventricles. When this His-Purkinje conduction is abnormal, the resulting sequence of the both ventricular contraction should be changed. These abnormal mechanical consequences resulting from abnormal conduction system have been difficult to demonstrate because these are very rapid and complex. We evaluate the phase angle analysis using radionuclide gated blood pool scan(GBP) as a quantitative method which can determine the asynchronous contraction of left ventricule in patients with complete left bundle branch block(C-LBBB, 20 cases) and complete right bundle branch block(C-RBBB, 15 cases). The results as follows : 1) The ejection fractions, peak ejection rates, in GBP were significantly decraesed in patients with C-LBBB compared with controls(10 cases, 70± 4.2 vs 44± 13.9%, 3.51± 0.62 vs 2.48± 0.98, p<0.05 by t-test respectively). The peak filling rates were also decreased in patients with C-LBBB(3.38± 0.92 vs 1.76± 0.71, 1A.05). 2) In the phase angle analysis, the standard deviations and the width of half maximum of phase angle were significantly increased in patients with C-LBBB(8.6± 1.8 vs 20.6± 18.1, 16.0± 3.9 vs 22.5± 9.2, p<0.05 by t-test respectively). And the ranges of phase angle were also increased in C-LBBB(51.3± 5.4 vs 95.7± 31.7, p<0.05). 3) But there were no significant differences in GBP and phase angle analysis between patients with C-RBBB and controls. As the results above, it can be concluded that the phase angle analysis can provide an accurate noninvasive method to detect the asynchronous contraction in patients with abnormal intraventricular electrical activation.

내독소로 유발된 삼추성 중이염에서 TNF-α Inhibitor의 효과

전은주,박용수,최영철,이정학 대한이비인후과학회 2000 대한이비인후과학회지 두경부외과학 Vol.43 No.10

고콜레스테롤 혈증 환자에서 Cerivastatin(LIPOBAY, 의과학연구소)의 임상효과 및 안전성에 관한 연구

박성훈,김미연,정수진,이영숙,박창한,변은경,전성희 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

목적 : Cerivastatin(LIPOBAY)은 최근에 개발되어 사용되기 시작한 HMG-CoA 환원효소 억제제로서 저용량으로 탁월한 콜레스테롤 강하효과를 보이는 약물이다. 저자들은 Cerivatatin(LIPOBAY)의 혈중 콜레스테롤 강하효과를 평가하고 약물의 안전성을 평가하기 위하여 본 연구를 시행하였다. 방법 : 고콜레스테롤혈증 환자 37명(남자 13명, 여자 24명)을 대상으로 하였다. 대상환자는 2주간의 저콜레스테롤 식이 후에도 혈청 콜레스테롤이 240㎎/㎗이상이거나, 관상동맥질환이 있는 환자는 혈청콜레스테롤이 220㎎/㎗이상인 경우 cerivastatin 0.4㎎을 8주간 복용하도록 하였다. 임상적 관찰과 검사실 검사(간기능검사, 일반혈액검사, 혈청지질검사)는 투약개시 후 4주 및 8주 후에 시행하였다. 결과 : Cerivastatin 0.4㎎을 4주간 투여한 후 측정한 LDL 콜레스테롤, 총콜레스테롤, triglyceride, 및 HDL 콜레스테롤은 각각 38%, 28.8%, 11.6% 및 7.8% 감소하였다. 총콜레스테롤/HDL 콜레스테롤 비 및 LDL/HDL비는 각각 20.8% 및 31.1% 감소하였다. 투약 8주후에 측정한 검사소견은 4주후에 비해 유의한 변화를 보이지 않았다. 한명의 환자(2.7%)에서 간기능 검사상 AST, 및 ALT의 지속적인 상승으로 투약을 중지하였다. 결론 : Cerivastatin 0.4㎎/day는 혈청콜레스테롤을 효과적으로 감소시켰으며 심각한 부작용은 볼 수 없었다. 따라서 적극적으로 LDL콜레스테롤을 낮출 필요가 있는 고콜레스테롤혈증 환자에서 cerivastatin은 효과적이고 안전한 약물이라고 생각된다. Objectives : Cerivastain(LIPOBAY) is recently developed HMG-CoA reductase inhibitor which is effective in lowering serum cholesterol levels at microgram does. We evaluated the clinical efficacy and safety of cerivastatin(LIPOBAY) in patients with hypercholesterolemia. Method : Thirty-seven patients(male : 13, female : 24) with hypercholesteolemia defined as baseline serum total cholesterol ≥240㎎/㎗, or ≥220㎎/㎗ in patients with known coronary artery disease were included for this study. After 2 weeks of low cholesterol diet, if the serum total choesterol level meet the criteria, cerivastain 0.4㎎/day was prescribed for 8 weeks. Clinical follow-up and laboratory tests were performed 4 weeks and 8 weeks after medication. Results : After 4 weeks of cerivastain 0.4㎎/day treatment, low density lipoprotein(LDL) cholesterol decreased 38% and total cholesterol decreased 28.8% from baseline. Triglyceride decreased 11.6%, and high density lipoprotein(HDL) cholesterol decreased 7.8% from baseline. Total cholesterol/HDL ratio decreased 20.8% and LDL/HDL ratio decreased 31.1% from baseline. After 8 weeks of treatment, no further significant changes were noted compared with the values at 4 weeks. Cervastatin was discontinued in one patient(2.7%) due to continuous liver enzyme elevation. Conclusion : Cerivastatin 0.4㎎/day is effective in lowering serum cholesterol levels without significant adverse reactions. Cerivastatin is effective and safe for patients with hypercholesterolemia who needs aggressive LDL cholesterol lowering.

주문형 비디오 시스템에서의 데이타 저장 및 디스크 스케줄링 기법

전용희,박은미 대구효성가톨릭대학교 응용과학연구소 1997 응용과학연구논문집 Vol.5 No.-

Generally speaking, I/O capability and storage requirements are more important than computing capability in a video system. The gap between processor performance and I/O system is expected to widen continuously. Therefore, the disk system typically becomes the bottleneck in a Video-On-Demand(VOD) system. Data storage in a VOD server is different from that of conventional file server in respect to the points that needs real-timeliness and requires large storage capacity. The conventional storage servers are not also geared to handle the demands of applications that deal with continuous media. In this paper, we made a survey of the placement methods for mutimedia data strage and presented a VOD data structure which can minimize the seek overheads in retrieval and maximize the throughput, thus may result in a substantial increase in the access efficiency for storage and retrieval. Using the data structure, we simulated the disk system in a VOD server and compared the performance of some disk scheduling schemes.

헤파셀정의 cross-over test에 의한 국내시판 제제와의 생물학적 동등성 시험

박은전,이성희,이미현,김혜주,손동환,고건일,김재백 圓光大學校 藥品硏究所 1995 藥品硏究所報 Vol.10 No.1