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      • Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

        장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

        의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

      • 전류 비유 모델에 의한 초등학생의 전류 개념 변화 분석

        유병길,강인석,김병철,남만희,박선희,소하연,윤희정,이영아,이하룡,전병문,정승호 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-

        There exists a major impediment to learning electricity which may illuminate why direct presentation of scientists' ideas is too aggressive a strategy. This impediment lies in thinking that electricity is used up and in envisaging the light bulb as a consumer. This view is based on a powerful idea which summarises much of our experience; it declares that 'things get used up', 'you cannot get something for nothing', and 'intuitive thinking'. To replace this view with scientific view, we made the analogy model. It is suggested that the analogy model is more effective in teaching electricity circuits than conventional teaching method.

      • 저항성-밴드 운동이 제 2형 당뇨 비만여성의 Leptin과 Glucose Tolerance에 미치는 영향

        이규성,김문희 한국체육대학교 체육과학연구소 2001 국제학술대회논문집 Vol.20 No.1

        To evaluate the effect of band-resistance training on serum leptin levels 20 obese subjects with type 2 diabetes were enrolled in 6 weeks of band-resistance training. The training program consisted of band exercise for 40min at least 5 times per week, with the intensity of exercise maintained at 50% of 1RM. Serum leptin levels decreased significantly in the exercise training (TR) group (from 9.07±2.04 to 6.80±2.29ng/mL, P<.05), but not in the sedentary (SED) group (from 7.80±1.75ng/mL to 6.33±1.19ng/mL). Body weight and percentage body fat decreased in the exercise training (TR) group (from 58.9±3.0kg to 52.6±3.5kg; from 40.1±2.5% to 25.6±2.7%. but not in sedentary (SED) group. however, The concentrations of plasma insulin and NEFAs did not differ between the groups either before or after exercise training. After 6 weeks of band-resistance training, the relationship between plasma leptin and each variable (insulin, glucose, NEFAs and body weight, fat mass and lean body mass) were studied. Pearson correlation coefficient revealed that the concentration of plasma leptin was correlated with the change in body weight (r=.842, p<05) and (body fat amass (r=.896. p<.05). This study demonstrates that band-resistance training in obese women with type 2 diabetic subjects reduces seam leptin levels dependent of changes in body fat mass during 6 weeks of band-resistance training.

      • 日本의 人文·社會科學 硏究動向 調査

        李注衡,朴仁熙,韓點洙,金文基,朴晋泰 慶北大學校 1983 論文集 Vol.36 No.-

        In January 1983, the writer visited a few universites in Japan to survey the recent trend of studies in cultural and social Sciences. At that time what I researched is as follows; In Japan, many a learned society has been organized and the research activities were very lively. Mass publication of scientific periodicals and prompt translation of foreign writings showed the maturity of scientific atmosphere. It true that their study of literature has been performed on the basis of positivism since 1930'. But now Structuralism which consider's literary works as one organic unity of parts became the main basis of literary studies. And, Learned Society of Educational Law has been organized in Japan. In consequence, the level of researches in educational law could be remarkably high. So, it is necessary for us to study the law of education. For, to make it better, we must know not only the universal principles of education but also specific ones derived from the peculiar characteristics of Korean education. At the same time, in Japan, Department of the Law of Industrial Administration was established in 14 universities including Japan University. And with the help of it, companies could improve the efficiency in dealing with judicial affairs related with industrial administration. So, to be a winner in the international trade competition, it is also required for us to study the judicial affairs of industrial administration.

      • KCI등재

        A. 高校 科學 (生物·地球科學) 및 數學科 探究學習의 評價模型 定立과 評價紙 開發

        李相協,權炳奎,林在圭,孫文求,吳岱燮,楊洪準,梁承榮,姜用熙,林成圭,金正遠,金吉民,兪正在 경북대학교 과학교육연구소 1982 科學敎育硏究誌 Vol.6 No.-

        Currently the evaluation of high school science and mathematics learning has been too much knowledge-centered without concerning the inquiring ability or scientific attitude. This study, therefore, was made for the purpose of establishing of evaluation model for high school science (biology and earth science) and mathematics learning and its evaluation items. In this paper, the research was done about three fields, biology, earth science and mathematics. 1. For the biology, the evaluation methods of inquiry learning were studied with the foreign references, and proper evaluation items were suggested. 2. For the earth science, after analizing 5 kinds of earth science textbook of current using in high school, essential 19 items were selected. 5 of them were tested in test group and control group, then, the results were analized. 3. For the mathematice, the teaching elements of「Set」and「Flow chart」in mathematics (Ⅰ) were selected and structured. Detailed teaching objects were established and evaluation items were introduced.

      • KCI등재

        솔잎혹파리 피해임지의 수세변동에 관한 연구

        이찬용,채희문,김종국 강원대학교 삼림과학연구소 2000 Journal of Forest Science Vol.16 No.-

        솔잎혹파리 피해임지의 특성에 따른 수세변동을 구명하였다. 솔잎혹파리 피해도(「심), 「중), 「경))별로 구분하여 수세를 조사한 결과 피해가 심한 지역의 수목은 수세가 현저하게 약화되었으며, 수목의 임분밀도(「밀), 「중),「소」)별로 구분한 경우는 피해도와 관계없이 임분밀도가 낮은 임분에서 수목의 수세가 강하게 나타났다. 수목의 외형적 인자중 수관폭과, 흉고직경이 작은 개체에 비하여 큰 개체의 수세가 모든 임분에서 강하게 나타났다. 각 임분에서 전기저항치와 수관면적과의 관계는 피해도 「심」 임분에서는 수관면적이 13.4m2, 「중」 임분에서는 10.9m2, 「경」 임분에서는 7.9m2로 피해가 심할수록 수관면적이 넓어야 임목이 생존할 가능성이 높은 전기저항치(15kΩ이하)가 나타나는 것으로 파악되었다. This study investigated tree vigor of damaged forest by Thecodiplosis japonensis Uchida et Inouye. In damaged forest by pine gall midge, the investigation result of damaged rate section(severe, moderate, light) indicated that severe stand showed higher value of electric resistance(kΩ) than that of light stand, the investigation result of tree density section(crowed, middle, little) indicated that crowed stand showed higher value of electric resistance than that of little stand(the value of electric resistance at which low reading show high vigor tree and high reading low vigor tree). The crown width and DBH(diameter of breast height) of external factors showed lower value of electric resistance than that of small size. The results of comparative between Crown area and value of electric resistance in each stand were 13.4m2 in severe stand, 10.9m2 in moderate stand and 7.9m2 in light stand. Therefore, the tree which have big crown showed low value of electric resistance(below 15kΩ)that has high possible of survial. Key word : Thecodiplosis japonensis, electric resistance, crown area

      • 12주간의 써키트 웨이트트레이닝이 중ㆍ장년기 남성의 건강관련체력에 미치는 영향

        이규성,김문희,오경택,김범수 한국체육대학교 체육과학연구소 2000 韓國體育大學校附屬 體育科學硏究所論文集 Vol.19 No.1

        The purpose of this study is to examine the change of health related physical fitness. The study conducted the experiment with 24 participants; three groups fo eight participants in each age group(40, 50 and 60's) The subjects are members of the G sports center. The results of this study are as followed. According to comprehensive results of the research, circuit weight training for 12 weeks appears to give a positive effects on middle aged men's health, and that large increase in body fat and lower strength is not an unavoidable result of aging but the result of an unhealthy life style. Putting the proper training for the middle-aged group into systematic and regular practice, exercise can delay the normal aging process and also maintain relative good health physiologically. I think we need to develop more rational and scientific exercise programs to build up physical strength and improve health.

      • 4주간의 쥐뒷다리 고정이 Soleus근섬유 조성에 미친 영향

        이선장,김완조,김문희 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

        The purpose of this study was to examine the effect of immobilization on muscle fiber composition, mass, area and capillarization after 4 - wk of hindlimb suspension. Significant reductions in soleus mass, area and capillary density were occured after 4 wks of hindlimb suspension, Wheres type IIa fiber percentage was significantly increased in the experimental group. The results suggest that hindlimb unweighting induced soleus muscle atropy and these results also demonstrate that muscle fiber atropy not necessarily being associated with a loss in capillary supply.

      • 아미노산 투여가 운동중 싸이클선수의 젖산 및 심박수에 미치는 영향

        이승국,유병렬,김문희,김완조,이선장 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

        The purpose of the study was to determine whether a 15.6mg.Kg ??' does of glutamate given one hour prior to incremental exercise test would reduce the lactate formation. Five well trained cyclists served as subjects in this experiment which included a placebo and glutamate trial. The subjects initially work on treadmill 200m/min for 3 minutes and here increased the workload by 20m/min every 3minutes until exhaustion. Blood lactate were collected from finger-tip. Subjects in the glutamate trial showed significantly lower lactate formation during exercise then they did in the placebo trial. In both groups no significant difference was found on heart rate. During the recovery lactate and heart, rate were unaltered in either the glutamate or placebo trials. In summary, glutamate ingestion may reduce lactate formation resultly improvement of performance.

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