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      • KCI등재

        Co-occurrence 네트워크 분석을 활용한 외국인 관광객의 제주 문화관광자원 경험구조: 글로벌 OTA의 온라인 리뷰 및 평점을 대상으로

        윤희정 강원대학교 경영경제연구소 2024 Asia-Pacific Journal of Business Vol.15 No.1

        Purpose - This study conducts the co-occurrence analysis, one of the social network analysis using global OTA’s online reviews and grades in order to understand the experience structure of foreign tourists visiting cutural tourism resources in Jeju, Korea. Design/methodology/approach - For this purpose, this study selects 6 cultural tourism resources in Jeju as the study sites, and collects qualitative review data (noun, adjectives, and verb) and quantitative grade data. Findings - The co-occurrence network analysis between words and grade of market and street shows that the grade of 5 appears the most simultaneous with pork, buy, lot, try, fresh, black, food, price, seafood, local, market, good, street, etc. and the grade of 1 connects with small, dish, better, taste, etc. And the co-occurrence network analysis between words and grade of tradition and folklore shows that the grade of 5 appears the most simultaneous with village, place, museum, visit, time, life, culture, women, diver, use, lot, etc. and the grade of 1 connects with minute, spend, room, recommend, honey, etc. Research implications or originality - The above research results are relevant in order to find out the core experience of foreign tourists using online review and grade generated by foreign tourists and use as the important information to develop the strategies related to the planning and management of cultural tourism resources.

      • KCI등재

        A Case of Multidrug-Resistant Salmonella enterica Serovar Typhi Treated with a Bench to Bedside Approach

        윤희정,Soung Hoon Cho,Seong Han Kim 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.1

        We report a relapsed case of a 25 year-old man with multi-drug resistant Salmonella serovar Typhi (MDRST) bacteremia who had recently returned from travel in India. Due to unresponsiveness to ciprofloxacin and ceftriaxone, we examined the strain’s resistance to quinolones and extended-spectrum β- lactamases (ESBLs). The strain had a single gyrA mutation at codon 83 (Ser83Phe), which explains its decreased susceptibility to fluoroquinolone and resistance to nalidixic acid. In the screening tests of ESBLs, TEM-1 was positive, which is beta-lactamase but not ESBL. The patient was finally successfully treated with meropenem and aztreonam. In the presence of clinical unresponsiveness despite favorable sensitivity tests, further laboratory evaluations are needed, which should include studies of genes related to antibiotic resistance and ESBLs. In addition, further prospective trials should be done about the possible inclusion of antibiotics not yet mentioned in the current guidelines. With MDRST on the rise worldwide, the most optimal and effective line of antibiotic defense needs to be devised.

      • KCI등재

        日本語の授受動詞習得における母語の影響 -韓國人日本語學習者と中國人日本語學習者を比較して-

        윤희정 한국일본어문학회 2009 日本語文學 Vol.41 No.-

        本硏究は、日本語學習者の授受動詞の習得における母語の影響を授受本動詞と授受補助動詞ごとに檢討したものである。調査對象者は日本で日本語を學習している韓國人日本語學習者と中國人日本語學習者である。調査資料は學習者が繪をみて授受動詞文を書く文産出テストを用いた。その結果、授受本動詞と授受補助動詞の習得は學習者の母語によって異なるが、それは習得促進であり、習得順序は變わらないことがわかった。また授受本動詞の場合は韓國人學習者のほうが中國人學習者より習得が進んでいるのに對して授受補助動詞の場合は中國人學習者のほうが韓國人學習者より日本語母語話者の受益動詞の使用狀況(「てくれる」<「てもらう」)に早く近づいていくことがわかった。つまり、日本語の授受動詞の習得において母語の影響は授受本動詞の場合とそれが文法化した授受補助動詞の場合で異なっていた。

      • KCI등재

        Widdrol에 의한 인간 자궁경부암 세포주의 Apoptosis 유도

        윤희정,정종헌,권현주,현숙경,최영현,박정하,김병우 대한암예방학회 2011 Journal of cancer prevention Vol.16 No.3

        In this study, the anticancer activity of widdrol, essential oil compound isolated from Juniperus chinensis,is investigated in human cervical cancer HeLa cells. Widdrol inhibits the growth of HeLa cells in a dose- and time-dependent manner. To confirm whether these effects of widdrol are associated with apoptosis, apoptotic features and expression of apoptosis-related proteins are examined. As a result, typical morphological characteristics of apoptotic cells such as formation of apoptotic body was observed as measured by DAPI staining. In Western blot analysis, the expression of anti-apoptotic Bcl-2 and Bcl-XL were decreased and cytosolic cytochrome c was increased in cells treated with widdrol. Also, caspase-8and caspase-9, which are initiator caspase each in extrinsic and intrinsic pathway, were activated, activation of executioner caspase (caspase-3) and proteolytic cleavage of PARP were also observed. Therefore,widdrol seems to induce apoptosis by activating both intrinsic and extrinsic pathway in HeLa cells at the same time. (Cancer Prev Res 16, 255-262, 2011)

      • KCI우수등재

        도심 도보관광자의 계절별 시․공간 이동밀도 및 멈춤 특성 -북촌한옥마을의 봄․여름 관광자들을 대상으로-

        윤희정,강동진,신상현 한국조경학회 2019 韓國造景學會誌 Vol.47 No.4

        The purpose of this study is to determine urban walking tourists’ spatiotemporal movement densities and the stopping characteristics by season. With the Bukchon Hanok Village in Seoul, as the study site, a GPS-based smartphone application collected spatiotemporal data, and GIS and statistical methods were used to analyze the urban walking tourists’ spatiotemporal activities in the spring and summer. The results show that the moving and staying variables of urban walking tourists differ significantly by season. In addition, spatiotemporal movement densities and stopping characteristics using ArcGIS’s tools show clear spatial and temporal concentrations along the main access roads and commercial areas of the study site in the spring and summer. Policy-makers and developers of urban walking tours should use these spatiotemporal concentrations of walking tourists to define policies that would control the capacities of urban walking areas and distribute tourists spatially and temporally. 본 연구는 계절에 따라 도심 도보관광자들의 시․공간 이동밀도 및 멈춤 특성 분석을 주요 연구목적으로 한다. 이를 위해 본 연구는 서울 북촌한옥마을을 연구대상지로 선정하고, GPS 기반 스마트폰 어플리케이션을 활용하여 도심도보관광자들의 시․공간 행태 데이터를 수집하였다. 이에 기초하여 본 연구는 GIS와 통계적 접근방법을 이용하여 봄, 여름 도심 도보관광자들의 시․공간 이동행태를 분석하였다. 주요 연구결과, 도심 도보관광자들의 이동 및 체류특성은 계절별로 통계적 차이가 검증되었다. ArcGIS를 이용하여 도심 도보관광자의 시․공간적 이동밀도와 멈춤 특성을 분석한 결과, 대상지로의 중심 접근로와 상업공간에 있어 공간적․시간적 집중성이 확인되었다. 도심 도보관광관련 정책입안자나 개발자들은 본 연구결과의 시․공간 밀집도를 활용하여 도보관광지의 수용력 조절이나 관광자들의 공간적 혹은 시간적 분산정책 수립에 활용할 수 있을 것이다.

      • KCI등재후보

        사회복지지원기관의 직무역량 향상을 위한 교육체계 개발 연구: FGI를 중심으로

        윤희정,정향윤 순천대학교 교육과학연구소 2023 현장수업연구 Vol.4 No.1

        In this study, FGI was performed on members by job and position to develop an educational system to enhance the job competency of specialized institutions to support the social welfare system in Korea. Through the process of this study, job competencies for experts in the social welfare field were derived by areas of knowledge, skills, and attitudes, and an education system was constructed accordingly. First, as the derived job competency, professional knowledge for each job in the knowledge area, understanding social trends, social welfare-related legal knowledge, planning ability, communication ability, problem identification and solution ability in the skill area, and writing and publicity in other skills In the areas of , language, administrative ability, and attitude, there are interpersonal skills, leadership attitude, altruism, external relations ability, self-development ability, situation judgment and crisis coping ability, etc. Based on the derived competencies, the education system was composed of three tracks: leadership course, job competency and self-development, and statutory compulsory education. 본 연구는 우리나라 사회복지제도의 지원 전문기관의 직무역량 제고를 위한 교육체계 개발을 위해 직무별, 직급별 구성원에 대한 FGI를 수행하였다. 본 연구의 과정을 통하여 사회복지분야 전문가를 위한 직무역량을 지식, 스킬, 태도의 영역별로 도출하였으며, 이에 따른 교육체제를 구성하였다. 먼저, 도출된 직무역량으로는, 지식영역에서 업무별 전문지식, 사회적 트렌드 이해, 사회복지관련 법령지식, 스킬영역에서 기획능력, 의사소통능력, 문제파악 및 해결능력, 그리고 기타능력으로 글쓰기, 홍보, 어학, 행정 능력, 태도영역에서는 대인관계능력, 주도적 태도, 이타심, 대외관계능력, 자기개발능력, 상황판단 및 위기대처 능력 등이 있다. 도출된 역량을 기반으로 교육체계를 리더십 과정, 직무역량 및 자기계발, 법정의무교육의 세 개 트랙으로 구성하였다.

      • KCI등재

        외국인 대학원생 튜터와 한국인 대학생 튜티의 MOOC 학습 튜터링의 효과

        윤희정 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.20

        Objectives The aim of this study was to investigate the effects of Korean college students’ MOOC learning tutoring with international graduate students and Korean college students. This study also look into the effects of the attitude toward English speaking and communication competency. Methods For this aim, 5 international graduate students were chosen as the tutors, and 15 Korean undergraduate students were chosen as the tutees in order to participate in this study. Tutoring team consisted of one international graduate tutor and 3 Korean college student tutees. They were asked to conduct tutoring with MOOC course learning material for 10 weeks. In order to get the data, they are asked to take a pre and post English speaking test and the questionnaires of the perceptions on a English speaking and communication competency. The data collected were analyzed statistically. Results The results indicate that the Korean students’ speaking performance was improved significantly in the post test compared to the pre test. In particular, fluency is more improved than correctness and complexity. In addition, Korean college students’ attitude about English speaking and communication competency was shifted to more positively. Conclusions Korean college students’ MOOC learning tutoring with international graduate students is effective to improve Korean college students’ English speaking competency and have positive influence on the attitude toward English speaking and communication competency. 목적 본 연구에서는 외국인 대학원생 튜터와 한국인 대학생 튜티의 MOOC 학습 튜터링이 영어 말하기 능력과 영어 말하기 인식, 의사소통 능력의 인식에 대하여 어떤 영향을 미치는지 살펴보는 것이다. 방법 이를 위하여 우리나라 남부에 위치한 대학교에 재학중인 외국인 대학원생 5명과 한국인 대학생 15명을 선정하였다. 이들을대상으로 외국인 대학원생 튜터 1명과 한국인 대학생 튜티 3명으로 이루어진 MOOC 학습 튜터링 팀을 구성하여 10주 동안MOOC 학습 튜터링을 진행하였다. MOOC 학습 튜터링의 효과를 알아보기 위하여 튜터링에 참여한 15명의 한국인 대학생을 대상으로 영어 말하기 능력 평가와 영어 말하기에 대한 인식 및 의사소통 능력 인식에 대한 조사를 연구 전-후로 실시하였고 MOOC 학습 튜터링 참여 소감에 대하여 인터뷰하였다. 결과 연구 결과로서 나타난 MOOC 학습 튜터링의 효과는 다음과 같다. 첫째, 영어 말하기 능력 평가 점수가 향상되었다. 영어 말하기능력 평가를 구성하는 세부 영역에서의 향상도는 유창성, 복잡성, 정확성 순서로 나타났다. 둘째로 영어 말하기에 대한 인식 및의사소통 능력에 대한 인식이 긍정적으로 변화하였다. 영어 말하기 인식의 하위 영역인 언어적 영역과 정의적 영역 두 영역에서 점수가 향상되었다. 셋째로 의사소통 능력에 대한 인식에서도 긍정적인 변화가 나타났다. 의사소통 능력 인식의 하위 영역인 적극적 경청과 이해, 주제이해, 상호이해, 배려, 질의응답 모두에서 점수가 향상되었는데, 특히 배려영역의 점수 향상도가 가장 높았으며, 질의응답에서의 향상이 두 번째로 높게 나타났다. 결론 본 연구에서 도출한 결과는 외국인 대학원생 튜터와 한국인 대학생 튜티의 MOOC 학습 튜터링이 영어 말하기 능력 향상에효과적이며, 영어 말하기와 의사소통 능력에 대한 인식에 긍정적인 영향을 미쳤음을 증명하고 있다.

      • KCI등재

        A short-term clinical study of marginal bone level change around microthreaded and platformswitched implants

        윤희정,박정철,윤정호,정의원,김창성,최성호,조규성 대한치주과학회 2011 Journal of Periodontal & Implant Science Vol.41 No.5

        Purpose: The marginal bone levels around implants following restoration are used as a reference for evaluating implant success and survival. Two design concepts that can reduce crestal bone resorption are the microthread and platform-switching concepts. The aims of this study were to analyze the placement of microthreaded and platform-switched implants and their short-term survival rate, as well as the level of bone around the implants. Methods: The subjects of this study were 27 patients (79 implants) undergoing treatment with microthreaded and platformswitched implants between October 2008 and July 2009 in the Dental Hospital of Yonsei University Department of Periodontology. The patients received follow-up care more than 6 months after the final setting of the prosthesis, at which time periapical radiographs were taken. The marginal bone level was measured from the reference point to the lowest observed point of contact between the marginal bone and the fixture. Comparisons were made between radiographs taken at the time of fixture installation and those taken at the follow-up visit. Results: During the study period (average of 11.8 months after fixture installation and 7.4 months after the prosthesis delivery),the short-term survival rate of microthreaded and platform-switched implants was 100% and the marginal bone loss around implants was 0.16±0.08 mm, the latter of which is lower than the previously reported values. Conclusions: This short-term clinical study has demonstrated the successful survival rates of a microthread and platformswitched implant system, and that this system is associated with reduced marginal bone loss.

      • KCI등재

        Vaccines against Coccidioides

        윤희정,Karl V. Clemons 대한내과학회 2013 The Korean Journal of Internal Medicine Vol.28 No.4

        Vaccines against fungal diseases are gaining attention because of their growing impact on modern medicine. Development of these vaccines should incorporate immunological tools that integrate with or replace chemotherapy to minimize antibiotic use and consequent resistance. In this review, we evaluate the current developmental status of fungal vaccines against coccidioidomycosis. There is a need for a vaccine that sufficiently prevents disease, without eradicating the fungus,by neutralizing adhesions and enzymes or other low penetrance virulence traits.

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