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      • 抗히스타민劑의 吸光度比法에 의한 定量

        李允中,李康春,李東宣,李振九 成均館大學校 1980 論文集 Vol.28 No.-

        The absorbance ratio method was applied to the quantitative determination of antihistamines, such as chlorpheniramine maleate(CPM), carbinoxamine maleate(CBM) and diphenhydramine hydrochloride. The influences of indicator and solvent concentration on the precision and accutacy of determination were investigated. And it was found that the effects of temperature and wavelength was negligible in case of averaging conditions. The standard deviations for three antihistamines tested were within 0.13%. As the results, the determination of antihistamines could be carried out easily, rapidly and accurately by the absorbance ratio method.

      • 3차원 Bending Machine 설계 및 신뢰성 평가에 관한 연구

        이춘만,임상헌,김현진 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

        This study is concerned about the development of a three-dimensional bending machine for heat exchanger. Recently, three-dimensional bending is required for various heat exchangers. The purpose of this study is the design of a three-dimensional bending machine by analysis of bending process, structural analysis simulation, and reliability evaluation of the machine by using a laser interferometer. The analysis is carried out by FEM simulation using DEFORM and CATLA V5 commercial software. The copper-tube is modeled by shell elements and the machine is modeled by placing proper shell and solid finite elements and fictitious mass properties to represent the real one. In addition, this machine has attained high accuracy repeatability. In order to improve the accuracy of this machine, the repeatability of feed, rotation, and bending are measured by a laser interferometer. The final results of analysis are applied to the design of three-dimensional bending machine and the machine is successfully developed.

      • Ⅲ-Ⅴ족 반도체의 연구 : GaAs의 합성, 단결성 및 특성 Crystal Growth and Characterization of GaAs

        이형재,김영기,신영진,박해용,정양준,최춘태,김병호,김진성 全北大學校 基礎科學硏究所 1982 基礎科學 Vol.5 No.1

        Temperature of 618 and 1250℃ at As and Ga sities respectively in the horizontal Bridgman furnace and growht speed of 0.7cm/h were found to be optimal for the production of single crystalline GaAs. Self-seeded and unintentionally doped GaAs crystals showd n-type characteristics with Hall mobillity of ∼0.75㎡/V-sec and carrier density of ∼10^19 m^-3 when the mesurements were made right after the growth. About three month later it was found that the same samples were converted to p-type GaAs. The analysis on the p-type sample showed that impurity scattering is dominant at around room temperature and thus the measured Hall mobility was 0.0065㎡/V-sec at 300K. 7.4±0.6 eV was obtained for acoustic deformation potential in the heavy hole band by fitting the theoretical conductivity and Hall coefficient to the corresponding experimental data. The value is very much higher than the theoretically estimated value, 3.6eV. The carrier density variation with temperature obtained from the present analysis gave 0.38 and 0.17 eV respectively for the activation energies of donor and acceptor.

      • 센서응용을 이한 CMOS열전대의 공정기술 개발

        이광만,김진섭,이춘흥,Liu, C.C. 경북대학교 센서기술연구소 1995 연차보고서 Vol.1995 No.-

        마이크로 열전센서는 마이크로히터와 열전소자로 구성된다. 열전도율이 낮고 내부응력이 최소화된 NON절연막 다이아프램을 LPCVD법, APCVD법 및 실리콘 이방성식각법을 각각 활용하여 형성하였다. Si_3N_4 및 SiO_2의 두께가 각각 1500Å 및 3000Å의 조합인 NON막이 가장 양호한 응력특성을 나타내었다. 고주파 스퍼터링법으로 형성된 백금박막을 이용한 히터와 온도감지기로 형성된 마이크로 가스유량센서를 제조하고 그 동작특성을 측정하였다. 유량센서의 동작특성은 100∼500sccm의 유량범위에서 양호한 선형성을 보였다. CMOS공정기술과 호환성을 갖는 마이크로 유량센서의 마스크패턴과 공정을 각각 설계하였다. A micro thermosensor is composed of a microheater and a thermo element. NON insulator diaphragm with low thermal conductivity and minimum internal stress was fabricated^by using LPCVD, APCVD and silicon anisotropic etch techniques. The deposited NON film represented the best stress characteristics when the thickness of Si_3N_4 and SiO_2 are 1500Å and 3000Å, respectively. A micro gas-flow sensor was fabricated and characterized that is consist of platinum thin film heater and temperature detector. The performance characteristics of the micro gas-flow sensor shows a good linearity within 100-500sccm flow rate range. Mask pattern and CMOS process of micro gas-flow sensor have been designed according to CMOS process technology.

      • Systemic Lupus Erythematosus를 동반한 Multiple sclerosis

        이지현,이기주,윤성호,부귀범,손현화,박유환,정춘해,김진호,정원영 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

        Multiple sclerosis and lupus erythematosus are chronic, potentially disabling diseases of unknown cause. It is a rare occasion that the finding of both diseases occurs in one patient. Because both diseases may affect the central nervous system, it may be difficult at times to differentiate symptoms of lupus erythematosus from those of multiple sclerosis. As far as we know, there was no case report of SLE in multilple sclerosis in Korea. We report a case of multiple sclerosis accompanied by SLE.

      • Prospidin이 Mouse의 간장에 미치는 영향

        이규식,정호삼,이민형,백두진,기춘석 한양대학교 의과대학 1986 한양의대 학술지 Vol.6 No.1

        Prospidin, a new alkylating agent, has antimitotic and anticancer effect. Incubation with prospidin increases the stability of DNA and suppresses the incorporation of uridine into RNA by 15-20 percent. Prospidin is cytostatic for suspension culture and cells are blocked in G₂ phase of the cell cycle. The authors have demonstrated the effect of prospidin on the liver of mice histologically and histochemically and observed the cellular changes, loss of pyroninophilic granules and accumulation of fat in the hepatic parenchymal cells. Sixty-five healthy mice of ICR strain, average weight being 20g, were divided into two groups; control and prospidin-treated groups. All experimental animals were administered foo and water ad libitum. Animals of the prospidin-treated groups were administered prospidine 500mg per kg of body weight intraperitoneally fter dilution in the water for injection. Animals of the control group were administered only water for injection. Prospidin treated animals were sacrificed at intervals of 6, 12, 24, 36 and 48 hours after administration of prospidin. Histological preparations were made by way of hematoxylin and eosin stain for the cellular changes, methyl green-pyronin stain for pyroninophilic granules and oil red O stain for fat accumulation in the mouse liver. The results obtained are as follows. 1. Cellular swelling associated with vesicular formation were observed in the hepatic parenchymal cells of entire hepatic lobule at 24 and 36 hours after administration of prospidin. 2. A marked reduction of the pyroninophilic granules were observed in the hepatocyte of he whole hepatic lobule at 24, 36 and 48 hours following drug administration. 3. Fat deposits in the hepatic lobule were seen at 36 hours after administration of prospidin. It is suggested that prospidin acts as a cytotoxic agent and causes cellular swelling with vesicular formation, loss of pyroninophilic granules, and fat accumulation in the parenchymal cells of the liver.

      • 혀에 작용하는 capsaicin에 관한 감각 정보의 특성

        이배환,김기석,김기영,진춘조,나흥식,홍승길 한국심리학회 1999 한국심리학회지 생물 및 생리 Vol.3 No.1

        본 연구는 혀에 작용하는 capsaicin이 유발하는 감각 정보의 특성을 알아보기 위해 수행되었다. α-chloralose로 마취한 고양이에게 기계적 자극, 미각자극, capsaicin을 혀에 도포하고, 동통 유발 물질과 capsaicin을 혀의 동맥에 주입하면서 고삭신경과 설신경에서 신경의 활동을 기록하였다. 고삭신경에서 혀에 도포한 capsaicin에 대한 반응은 미각 자극 및 혀의 동맥에 주입한 동통 유발 물질에 대한 반응과 상관이 있었다. 혀의 혈관에 주입한 capsaicin에 대한 고삭신경의 반응은 혀에 도포한 capsaicin 및 혀의 혈관에 주입한 동통 유발 물질에 대한 반응과 상관이 있었다. 설신경에서 혀에 도포한 capsaicin에 대한 반응은 동맥에 주입한 동통 유발 물질에 대한 반응과 상관이 있었다. 혀의 혈관에 주입한 capsaicin에 대한 설신경의 반응은 혀에 도포한 capsaicin 및 혀의 혈관에 주입한 동통 유발 물질에 대한 반응과 상관이 있었다. 이러한 결과는 capsaicin이 혀에 작용할 때 동통뿐만 아니라 미각에 관한 정보도 유발한다는 것을 시사한다. 이때 미각에 관한 정보는 고삭신경을 통해 중추로 전달되며, 동통에 관한 정보는 설신경을 통해 전달되지만, 동통에 관한 정보가 고삭신경을 통해 전달될 가능성도 배제하지 못한다. The present study was performed to investigate the characteristics of sensory information produced by capsaicin in the tongue. Activities of the chorda tympani(CN) and lingual nerves(LN) were recorded while taste stimuli and capsaicin were being applied topically, and capsaicin and algesics were being injected intra-arterially to the tongue of cats anesthetized with α-chloralose. Responses of the CN fibers to topically applied capsaicin were correlated with those to taste stimuli and intre-arterially injected algesics. Responses of the CN fibers to intra-arterially applied capsaicin were correlated with those to topically applied capsaicin and intra-arterially injected algesics. Responses of the LN fibers to topically applied capsaicin were correlated with those to intra-arterially injected algesics. Responses of the LN fibers to intra-arterially aplied capsaicin were correlated with those to topically applied capsaicin and intra-arterially injected algesics. These results suggest that capsaicin provoke taste as well as pain sensation in the tongue. Taste information produced by capsaicin is conveyed to the brain via the CN and pain information via the LN. However, the possibility that pain information may be conveyed via the CN can not be excluded.

      • 생산·재고시스템에서의 리-드타임의 역할과 문제

        이홍우,이진춘 경북대학교 산업기술연구소 1987 産業技術硏究誌 Vol.14 No.-

        Lead time is a significant variable which, as well as demand, generates undesirable variation in production systems. Past studies looked upon the lead time as on uncontrollable factor, and analyzed errors of the lead time error without relating its error with to lot size. Although demand variations are system's external factor which system has no controlling measure, lead time can be managed becasue it is internal and process problem that has some rooms for improvement and reduction. This study analyzes the role and effects of the lead time and explains production/inventory system with priority given to lead-time and lot size. The analysis will be centered on MRP, JIT, OPT.

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