인천 일부지역 여중생의 식습관 및 나트륨관련 식행동 조사

백두진,이제혁,김명희 한국식품영양학회 2015 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2015 No.08

출생후 성숙에 따라 나타나는 흰쥐 십이지장 및 공장 점막의 alkaline phosphatase 활성에 대한 연구

백두진 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.2

The alkaline phosphatase, which is the hydrolytic enzyme of the phosphate salt in alkaline solution, acts on differentiation and maturation of cells and tissues, absorption and metabolism of nucleic acid and proteins. The author has investigated the change in the activity of alkaline phosphatase of the duodenal and jejunal mucosa of the rats according to biochemical and physiological maturation during early postnatal life. The experimental animals, which were obtained from litters deliveried, normally and randomly sampled adults, were sacrificed at the 1st, 5th, 10th, 20th, and 30th day after birth. The specimens of duodenum and jejunum were fixed in 10%-neutral formalin at 4℃ and sectioned 10㎛ thickness in cryostat. The activity of the alkaline phosphatase was evaluated histochemically by Gomori's method and the incubation time of sliced specimens was 30 minutes. The results were as follows. 1. In the neonatal rats of the 1st day after birth, the activities of the alkaline phosphatase were moderately positive in the epithelium and lamina propria of villi and weakly positive in the intestinal glands and its surrounding lamina propria of the duodenal mucosa. ANd the activities of alkaline phosphatase in the mucosa of the jejunum were moderately positive in the epithelium of the villi and weakly positive in the intestinal glands and lamina propria. 2. In the neonatal rats of the 5th day after birth, the activities of the alkaline phosphatase were moderately positive in the epithelium of apical and middle portion of villi. traceablely positive in the epithelium of basal portion and lamina propria of the mucosa of the duodenum. And the activities of alkaline phosphatase were moderately positive in the epithelium of apical and basal portion of the villi and weakly positive in the epithelium of middle portion of the villi. the intestinal glands and lamina propria of the jejumum. 3. In the neonatal rats of the 10th day after birth, the activities of alkline phosphatase were moderately or strong positive in the epithelium of the villi and weakly positive in the epithelium of the villi and weakly positive in the intestinal gland and lamina propria of jejunal mucosa. 4. In the rats of the 20th day after birth, the activities of alkaline phosphatase were strong or moderately positive in the epithelium of the villi, moderately positive in lamina propria of the core of the villi and the weakly positive in the intestinal glands and its surrunding lamina propria of duodenum. And the activities of alkaline phosphatase in the mucosa of the jejunum were strong positive in the epithelium of basal portion of the villi, intestinal gland and lamina propria of the villi and weakly positive in the lamina propria surrounding intestinal glands. 5. In the rats of the 30th day after birth, the activities of alkaline phosphatase were moderately or strong positive in the epithelium of the villi, modereate positive in the lamina propria of the villi and weakly positive in the intestinal glands and its surrounding lamina propria of the duodenal mucosa. And the activity of alkaline phosphatase was strong positive in the epithelium of apical portion of villi of the mucosa of the jejunum. Activity was decreased gradually and in the epithelium of basal portion of the villi activity was weakly positive. The activities were moderately positive in the intestinal glands and weakly positive in surrounding lamina propria of the glands and weakly positive in surrounding lamina propria of the glands of the jejunal mucosa. 6. In the rats of the adulthood, the activities of the alkaline phosphatase were strong positive in the epithelium of the villi and weakly positive in the intestinal glands and lamina propria of the duodenum. And the activities of alkaline phosphatase were moderately positive in the epithelium of the villi and weakly positive in the intestinal glands and lamina propria of the mucosa of the jejunum. Consequently, it is suggested that the activities of the alkaline phosphatase in the mucosa of duodenum and jejunum were increased by differentiation, growth, maturation and the changes of diet during early postnatal life, of the rats.

청년기 한국인 얼굴에 대한 계측적 연구 Ⅱ

백두진,안동춘,고기석 대한췌담도연구회 2000 대한췌담도연구회지 Vol.5 No.4

서울시 다가구⋅다세대 주택의 보행네트워크 기준대중교통 접근성의 지역별⋅계층별 특성에 관한 연구

백두진,김재태 한국부동산연구원 2016 부동산연구 Vol.26 No.3

This study analyzes public transit accessibility of multi-family housing in Seoul. The accessibilities are measured by the distance between each house to the nearest transit facility based on pedestrian network. The results can be summarized as follows : (1) Comparing inter-regional public transit, subway and main-line bus, between-region inequality of subway accessibility is greater than that of the main line bus accessibility. Within-region inequality degree of branch-line bus is greater than that of inter-regional public transit as well as local-line bus, which means more user oriented spatial allocation is needed. (2) In municipal level (administrative gu), while multi-family houses in Gangnam, Seocho, Eunpyung and Jungnang have higher level of accessibility and lower inequality degree, houses in Seodaemun and Jongro have lower accessibility and higher inequality. (3) Accessibility differences between public rental houses and other multi-family houses suggest more spatially unbiased locating of public housing. 본 연구는 서울시 소재 다가구⋅다세대 주택의 대중교통 접근성을 거주지로 부터 교통시설까지 이르는 보행 네트워크를 기준으로 측정하여 대중교통 수단별 접근성을 지역적⋅계층적 차원에서 분석하였고 그 결과는 다음과 같다. 첫째, 지역 간 교통수단인 지하철과 간선버스를 비교하면 지하철의 자치구 간 불평등이 간선버스 자치구 간 불평등 보다 더 큰 것으로 나타났다. 또한, 지역 내 이동수단인 지선버스의 지역 내 불평등은 또 다른 지역 내 이동수단인 마을버스뿐만 아니라 지역 간 이동수단인 지하철과 간선버스 보다도 높은 것으로 나타나 지선버스 정류장 배치에 있어 다가구⋅다세대 거주자들을 위한 고려가 필요한 것으로 보인다. 둘째, 자치구 차원에서는 강남구, 서초구, 은평구, 중랑구에 소재하는 다가구⋅다세대 주택들은 대중교통 접근성이 높고 자치구 내 불평등도 낮은 것으로 평가된다. 반대로 서대문구와 종로구에 속한 다가구⋅다세대 주택은 대중교통 접근성이 낮고 불평등도가 높다. 셋째, 마을버스를 제외한 모든 교통수단에서 일반주택과 임대주택의 대중교통 접근성에 차이가 있는 것으로 분석되어 임대주택의 입지선정 시 특정 교통수단 접근성에 편중되지 않도록 개선할 필요가 있다.

한국 성인과 옛사람의 이빨 형태에 관한 인류학적 연구

백두진,김희진,최종훈,김기덕 충북대학교 중원문화연구소 1999 중원문화연구 Vol.2·3 No.-

치아는 씹기와 발음뿐만 아니라, 미용적인 측면에서도 매우 중요한 역할을 담당한다. 또한 치아의 계측적, 비계측적 특징은 종족간 인류학적 비교나 고고학적 의의 그리고 개인의 신원 확인에 이용될 수 있으므로 체질인류학적, 고고학적 그리고 법치학적인 중요성을 갖는다. 그러나 이에 대한 연구가 국내에서는 활발히 이루어지지 않아 한국사람 치아의 체질인류학적 특성에 관한 포괄적인 자료는 찾아보기 힘들다. 이에 연구자들은 가야, 고려 및 조선인의 치아 1085 (71구)개와 한국 현대사람 남녀의 치아 1397 (96구)개를 대상으로 각 치아마다 5가지 항목은 계측하고, 9개 항목의 비계측 특징을 조사하였다. 이러한 치아 계측치와 비계측적 특징이 옛사람과 현대사람에서 나타나는 차이점을 비교하였다. 한국 옛사람과 현대사람 치아의 계측치들을 비교해 보았을 때, 치아의 얼굴쪽혀쪽 너비는 옛사람과 현대사람에서 계측치의 차이가 나타나지 않은 반면, 치아의 안쪽먼쪽 너비 항목에서는 약간의 차이를 나타내었다. 한국사람 치아의 비계측 특징을 조사해 본 결과, 위턱 안쪽앞니에서 삽모양앞니의 출현율은 옛사람에서 96.4%, 현대사람에서 94.2%를 보였으며, 위턱 가쪽앞니에서 삽모양앞니는 옛사람 93.1%, 현대사람 90.6%의 빈도로 옛사람에서 삽모양앞니의 출현빈도가 더 높았다. 아래턱 둘째작은어금니의 혀쪽 교두의 수를 비교한 결과, 옛사람에서는 1개 (48.0%) 또는 2개 (52.0%)의 혀쪽 교두만이 관찰되었으나, 현대사람의 아래턱 둘째 작은어금니는 1개 (52.3%), 2개 (46.7%) 또는 3개 (1.0%)의 혀쪽 교두를 가지고 있었다. 현대사람 위턱 첫째작은어금니에서 테라결절은 치아의 안쪽면에 나타난 경우가 53.7%로 가장 많았으나, 위턱 둘째작은어금니에서는 결절이 나타나지 않은 경우가 48.7%로 가장 많았다. 반면에 옛사람은 현대사람보다 더 높은 빈도의 테라결절 발현 양상을 보였다. 위턱 첫째큰어금니에서 교합면 고랑모양은 '4' 모양이 가장 많았으나 (옛사람 94.3%, 현대사람 94.3%), 위턱 둘째큰어금니에서는 '4-' 모양이 가장 많이 나타났다 (옛사람 40.5%, 현대사람 76.5%). 옛사람, 현대사람 모두에서 아래턱 첫째큰어금니 교합면 고랑의 형태는 'Y5' 모양이 가장 많았으며, 아래턱 둘째큰어금니에서는 '+4' 모양이 가장 많이 나타났다. Teeth play an important role in mastication and phonation as well as in esthetics. Since metric and non-metric characteristics of teeth can be used in anthropological comparison, archeology and identification, they are very important in anthropology, archeology and forensic odontology. However, this subject has rarely been studied in Koreans and therefore data on the anthropological characteristics are scarce. Researchers have measured 5 factors on each tooth and 9 non-metric characteristics of 1085 teeth collected from Gaya, Korea and Chosun people and 1397 teeth collected from the present Koreans (both female and male). Metric and non-metric traits the teeth were compared in past and present Koreans. Comparing the measurement of metric and non-metric traits, no difference in the faciolingual diameter was seen while slight difference was seen in the mesiodistal diameter of past and present Koreans. Non-metric characteristics of Koreans showed that 96.4% of past Koreans and 94.2% of present Koreans had shoveling in the maxillary central incisior while 93.1% of past Koreans and 90.6% of present Koreans had shoveling in the maxillary lateral incisor. Therefore shoveling was present in a higher rate in the past Koreans. The result on the comparison of the lingual cusp number on mandibular second premolars, showed that while past Koreans had 1 (48.0%) or 2 (52.0%) lingual cusps, present Koreans had 1 (52.3%), 2 (46.7%) or 3 (1.0%) lingual cusps. The Terra's tubercle was seen on the mesial surface in 53.7% of maxillary first premolar in the present Koreans and 48.7% of maxillary second premolar showed no tubercle. Meanwhile, past Koreans showed a higher rate of Terra's tubercle than present Koreans. The most common form of occlusal grrove pattern in the maxillary first molar was '4' (94.3% in past Koreans, 94.3% in present Koreans) and in the maxillary second molar was '4-' (40.5% in past Koreans, 76.5% in present Koreans). In both the past and present Koreans, The 'Y5' pattern of occlusal groove pattern was most common in the mandibular first molar and '+4' pattern in the mandibular second molar.

흰쥐에서 허혈시간에 따라 재관류후 나타나는 근조직의 미세구조 변화에 allopurinol이 미치는 영향

백두진,전재홍,Paik, Doo-Jin,Chun, Jae-Hong 한국현미경학회 1995 Applied microscopy Vol.25 No.3

It has been well known that ischemia and reperfusion injury to skeletal muscle following an acute arterial occlusion causes significant morbidity and mortality. The skeletal muscle, which contains high energy phosphate compounds, has ischemic tolerance. During the ischemia, the ATP is catalyzed to hypoxanthine anaerobically and hypoxanthine dehydrogenase is converted to xanthine oxidase. During reperfusion, the hypoxanthine is catalyzed to xanthine by xanthine oxidase under $O_2$, presence and that results in production of cytotoxic oxygen free radicals. These cytotoxic free radicals, $O_2^-,\;H_{2}O_2,\;OH^-$, are toxic and make lesions in skeletal muscle during reperfusion. The authors perform the present study to investigate the effects of allopurinol, the inhibitor of xanthine oxidase, on reperfused ischemic skeletal muscles by observing the ultrastructural changes of the muscle fibers. A total of 48 healthy Sprague-Dawley rats weighing from 200 g to 250 g were used as experimental animals. Under urethane(3.0mg/kg., IP) anesthesia, lower abdominal incision was done and the left common iliac artery were ligated by using vascular clamp for 1, 2 and 6 hours. The left rectus femoris muscles were obtained at 6 hours after the removal of vascular clamp. In the allopurinol pretreated group, 50mg/kg of allopurinol was administered once a day for 2 days and before 2 hours of ischemia. The specimens were sliced into $1mm^3$ and prepared by routine methods for electron microscopic observations. All preparations were stained with uranyl acetate and lead citrate, and then observed with Hitachi -600 transmission electron microscope. The results were as follows: 1. In 1 hour ischemia/6 hours reperfused rectus femoris muscles of rats, decreased glycogen particles and electron density of mitochondrial matrix and dilated terminal cisternae are seen. In 2 hours ischemia/6 hours repersed rectus femoris muscles of rats, mitochondria with electron lucent matrix, irregularly dilated triad and spheromembranous bodies are observed. In 6 hours ischemia/6 hours reperfused rectus femoris muscles of rats, irregularly arranged myofibrils, and many spheromembranous bodies, fat droplets and lysosome are seen. 2. In 1 hour ischemia/6 hours reperfused rectus femoris muscles of rats pretreated with allopurinol, decreased glycogen particle and dilated cisternae of sarcoplasmic reticulum and triad are observed. In 2 hours ischemia/6 hours reperfused rectus femoris muscles of rats pretreated with allopurinol decreased electron density of mitochondrial matrix and spheromembranous bodies are seen. In 6 hours ischemia/6 hours reperfused rectus femoris muscles of rats pretreated with allopurinol, mitochondria with electron lucent matrix, spheromembranous bodies and dilated cisternae of sarcoplasmic reticulum and terminal cistern are observed. The results suggest that the allopurinol attenuates the damages of the skeletal muscles of rats during ischemia and reperfusion.

GA 강판의 도금층 박리에 대한 인산염 처리의 효과

백두진 한국표면공학회 2003 한국표면공학회 학술발표회 초록집 Vol.2003 No.-

하지 허혈양상화가 흰쥐 간에서 발현되는 eNOS와 세포자멸사에 미치는 영향

백두진,이준희,전수경,서윤경 대한체질인류학회 2010 대한체질인류학회 학술대회 연제 초록 Vol.53 No.-

SOD, DMTU및 허혈양상화 처치가 허혈 및 재관류에 의한 흰쥐 넙다리곧은근의 미세구조 변화에 미치는 영향

백두진,임재현,정호삼,Paik, Doo-Jin,Lim, Jae-Hyun,Chung, Ho-Sam 한국현미경학회 1997 Applied microscopy Vol.27 No.3

The ischemia and reperfusion injury of the skeletal muscles is caused by generation of reactive oxygen during ischemia and reperfusion. It is well known that over 4 hours of ischemia injures the skeletal muscles irreversibly. The author has demonstrated the effects of SOD (superoxide dismutase), DMTU (dimethyl thiourea) and ischemic preconditioning on ultrastructural changes of the muscle fibers in the rectus femoris muscles after 4 hours of ischemia and 1 day and 3 days of reperfusion. A total of 72 healthy Sprague-Dawley rats weighing from 200 gm to 250 gm were used as experimental animals. Under urethane(1.15 g/kg, IP, 2 times) anesthesia, lower abdominal incision was done and the left common iliac artery was occluded by using vascular clamp for 4 hours. The left rectus femoris muscles were obtained at 1 and 3 days after the removal of vascular clamp. The SOD (15,000 unit/kg) or DMTU (500 mg/kg) were administered intraperitoneally at 1 hour before induction of ischemia. The ischemic preconditioned group underwent three episodes of 5 minutes occlusion and 5 minutes reperfusion followed by 4 hours of ischemia and 1 day and 3 days of reperfusion. The specimens were sliced into $1mm^3$ and prepared by routine methods for electron microscopic observation. All specimens were stained with uranyl acetate and lead citrate and then observed with Hitachi-600 transmission electron microscope. The results were as follows: 1. SOD or DMTU alone did not affect the ultrastructure of muscle fibers in the rectus femoris muscles. The electron density of mitochondrial matrix was decreased by ischemic preconditioning. 2. Dilated cisternae of sarcoplasmic reticulum, triad, mitochondria and the loss of myofilament in the sarcomere were observed in the 4 hours ischemia and 1 day reperfused rectus femoris muscles. Markedly changed sarcoplasmic reticulum, triad, disordered or loss of myofilament, indistinct A-band and I-band, and irregular electron lucent M -line and Z-line are seen in the 4 hours ischemia and 3 days reperfused rectus femoris muscles. 3. SOD reduced the changes of organelles in the muscle fibers of the 4 hours ischemia and 1 day reperfused rectus femoris muscles of the rats, but SOD did not affect the changes of muscle fibers in the 4 hours ischemia and 3 days reperfused muscles. On the other hand, DMTU markedly attenuated considerably the ultrastructural change of the 4 hours ischemia and 1 day or 3 days reperfused rectus femoris muscles. 4. By the ischemic preconditioning, the change was attenuated remarkably in the 4 hours ischemia and 1 day reperfused rectus femoris muscles. As the ischemic reperfused changes of muscle fibers were regenerated or recovered by ischemic preconditioning, the ultrastructures of them were similar to those of normal control in the 4 hours ischemia and 3 days reperfused rectus formoris muscles. Consequently, it is suggested that DMTU is stronger inhibitor to ischemic reperfused change than SOD. The ischemia and reperfusion-induced muscular damage is remarkably inhibited by ischemic preconditioning.

[지상 45] Norepinephrine, Propranolol, Isoproterenol, Diltiazem이 흰쥐의 왼심실근육층에서 세포자멸사와 Bcl-2, Bax의 발현에 미치는 영향

백두진,문준환,전수경,서윤경 대한체질인류학회 2005 대한체질인류학회 학술대회 연제 초록 Vol.48 No.-