한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

렘 콜하스의 'Luxurious place'에서 구현된 프로그램 해석과 공간조직 방법 연구 : New York, Los Angeles, San Francisco, 소재의 3대 'Prada'매장 분석 중심으로 focused on three 'Prada' shops in New York, Los Angeles, San Francisco

고대영,김현철 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

In relation with the society, the contemporary architecture has undergone various transformations of urban identities and has corresponded to them. Trying to figure out this relationship between the architecture and the society. The analysis of program that was materialized at the three "Prada" shops that were designed by Rem Koolhaas that were focused on fashion culture which are in New York, Los Angeles, San Francisco, and how the program is reflected to the space structure is being researched.

제2형 당뇨병 동물모델인 OLETF 쥐에서 장기간 라미프릴 투여가 내당능 및 췌도 베타세포에 미치는 효과

고승현,윤건호,김명미,안유배,송기호,유순집,손현식,차봉연,이광우,손호영,강성구 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.6

연구배경:최근 소개된 HOPE(Heart Outcomes Prevention Evaluation)study의 결과에 의하면, 심혈관질환이나 이에 대한 위험인자가 1가지 이상인 9,541명을 대상으로 안지오텐신 전환효소 억제제의 일종인 라미프릴을 투여하여 사망율과 뇌졸증, 심부전, 당뇨병 합병증이 개선되었을 뿐 아니라 다른 항고혈압제에 비해 새롭게 당뇨병으로 진단되는 환자가 줄었음을 보고한바 있다. 이에 저자들은 라미프릴(ramipril)을 제2형 당뇨병 동물모델에 장기간 투여함으로써 당뇨병을 예방하거나 고혈당 상태 또는 인슐린 감수성을 개선시킬수 있는지를 알아보고자 하였다. 방법:생후 24주된 체중 400∼450g의 OLETF와 LETO 쥐를 대상으로 6개월간 라미프릴 경구투여 하였고 혈압, 24시간 단백뇨 및 인슐린 내성검사를 시행하였다. 6개월 이후로는 8주간 투여군과 대조군의 체중을 비슷하게 맞추어 내당능 상태를 평가하였고 이후 다시 8주간 고농도 포도당을 투여하였다. 경구당부하검사를 시행한 후 희생시켜 조직표본을 만들어 guinea pig anti­human insulin 항체로 염색후 DAB로 발색하여 point count 법으로 베타세포를 정량하였고, 면역염색으로 췌도의 변화와 섬유화의 정도를 관찰하였다. 결과:라미프릴을 6개월간 투여하였을 때 OLETF 쥐에서 1)체중 증가가 적었으며 2)경구 당부하검사시 포도당하 면적은 의미있게 감소하였고 3)인슐린 내성검사상 Kitt가 증가되는 경향을 보였으며 4)수축기, 이완기 혈압과 24시간 단백뇨양이 의미있게 감소하였고 5)체중을 맞추면 내당능 상태가 비슷해졌다가 고농도 포도당 주입시 다시 포도당하 면적이 대조군에서 더 증가되었다. 라미프릴 투여군에서 췌도변형 및 파괴와 탈과립, 췌도내 섬유화가 감소하였다. 결론:본 실험에서는 인슐린 비의존성 당뇨병 동물 모델인 OLETF 쥐에서 당뇨병 발생 이전 단계부터 장기간 라미프릴을 투여할 경우 체중증가가 적었고, 투여군과 대조군의 체중을 맞추었을 때는 내당능상태의 차이가 없아가 고혈당 투여시 다시 투여군과 대조군에서 의미있는 차이를 보였다. 라미프릴 투여가 베타세포의 기능면에서 이로운 효과를 보일 것으로 생각되었다. 따라서 비만한 환자에서 안지오텐신 전환효소 억제제의 장기투여는 단백뇨 감소, 혈압강하 효과 이외에 체중증가의 억제 및 당뇨병 발생을 억제할 가능성을 시사한다. Background : In a Heart Outcomes Prevention Evaluation HOPE study, ramipril, a long-acting angiotensin-converting enzyme (ACE) inhibitor, significantly reduced the death rates the number of myocardial infarctions, strokes, heart failure as well as the risk of complications related to diabetes and of diabetes itself. However, it is known that ACE inhibitors improve glucose tolerance or insulin sensitivity or reduce the incidence of diabetes. Methods : 24 week-old OLETF (Otsuka Long Evans Tokushima Fatty) rats weighing 400 ~ 450 g were used in this study. 4 groups of rats were examined in parallel for 40 weeks. The OLETF rats were randomized for treatment with an aqueous solution of ramipril (5 mg/Kg) daily [OL (RMP), n=10)] and with saline [OL (CON), n=10)]. The LETO rats were also randomized in the same was as the OLETF rats (LT(RMP), n=10, LT (CON), n=10). The blood glucose level, body weight, systolic and diastolic blood pressure was assessed every month. At 3 and 6 months, the 24hrs urinary protein concentration was measured, and as insulin tolerance test and oral glucose tolerance test were conducted in all experimental groups. After 6 months, the body·weight was matched for 2 months in each corresponding group. Subsequently, a 15% sucrose loading was done for 2 months. After the glucose tolerance test, the pancreas was excised and immuno histochemical staining was conducted for insulin to quantify the beta cell mass by a point-counting method. In addition, the islet morphology was evaluated in the pancreas. Results : Ramipril treatment for a period of 6 months improved the 2hr blood glucose level, the area under the glucose curve in the oral glucose tolerance test, insulin sensitivity in addition to lowering significantly systolic and diastolic blood pressure and 24hrs urinary protein level significantly in OLETF rats. Of note, a lower weight gain was observed in both the ramipril-treated animals at 6 months. After weight matching, the AUC g and 2hr blood glucose level values were similar between the corresponding groups, but a 15% sucrose loading worsened the AUC g value. Histologically, the islets were less disorganized and the extent of fibrosis was lower in the ramipril-treated OLETF rats in the trichrome stain. Conclusion : Long-term treatment of ramipril, a long acting angiotensin-converting enzyme inhibitor may be useful for suppressing weight gain and proteinuria in addition to having a protective effect on the islet to harmful stimuli such as hyperglycemia (J Kor Diabetes Asso 25:469~482, 2001).

추간판 변성의 영상화: 자기공명영상과추간판 조영술의 비교

고현윤,김훈,이종언,신용범,김학진 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1

추간판 내 스테로이드 주입에 의한추간판의 조직학적 변화

고현윤,신용범,박재흥,설미영 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.2

종양의 성장 및 전이에 있어서 NF-κB의 역할

고현미,최정화,나명석,임선영 Official Journal of the Korean society for immunol 2003 Immune Network Vol.3 No.1

일상생활에서 겪는 고등학생의 스트레스요인과 대처방식에 관한 연구

고희숙,민현숙,정영숙 충북대학교 교육·생활연구소 1999 생활과학연구논총 Vol.2 No.-

The purpose of this study is to investigate the daily stressors of human relations, emotional lives, and economic lives which high school students go through and their coping strategies about these stressors, to provide the necessary materials and useful information for guiding students and educating their parents. The research questions of this study are: (1) the stressors of the male and female students in the general high school and their coping strategies, (2) the stressors of the high students according to the both sexes and their coping strategies, (3) the correlation between the stressors of high school students and their coping strategies. The subjects of this study consist of 320 students from a boys' high school and a girls' high school and 320 students from a coeducational high school. The test instruments used for this study can be divided into two categories; the test for measuring the stressors consisted of 75 items (7 subcategories) and the test for measuring the coping strategies consisted of 40 items. The data were analyzed by frequency distribution, percent, mean score, standard deviation, t-test, and simple correlation analysis. The main conclusions of this study were as follows: 1) When it comes to the stressors, students showed some differences depending on their sex. In terms of the relation between friends, male students have gone through more stresses than female students. 2) In terms of their coping strategies, male students from the boys' high school were shown to use more logical analysis strategies than those from the coeducational high school, male students from the coeducational high school usually used more receptive resignation strategies than those from the boys' high school, and also female students from the coeducational high school tended to employ more problem-solving and emotional discharge strategies than those from the girls' high schools. 3) The stressors vary depending on their sex. Male students have used more logical analysis, affirmative reevaluation, guide/support strategies, (which belong to the accessible coping strategies) and cognitive avoidance, emotional discharge strategies, (which are examples of avoidant coping strategies) than female students.4) As to the correlation between high school students' stressors and their coping strategies, it was shown that the correlation between stressors and logical analysis, affirmative reevaluation, and guide/support, problem-solving strategies (they all belong to accessible coping strategies) was higher than anything else.

리눅스를 이용한 로봇 제어용 실시간 운영 소프트웨어 설계

고낙용,노현창 조선대학교 에너지.자원신기술연구소 2001 에너지·자원신기술연구소 논문지 Vol.23 No.1

This paper presents a method for designing a real-time operation software for autonomous mobile robot control systems. Operation softwares for most of mobile robots were developed for its o m use. Sometimes, the operation software was developed based on MS-DOS or real-time kernel However, US-DOS has many restrictions for use as a robot operation system. Though some of operation softwares are based on the real-time kernels of UNIX 01- Windows NT. they were inadequate for use with mobile robots. So, in this paper, we focus on building an operation software real-time kernel based on Linux. The software modules of Task Management, Memory Management, Intertask Communication, and Synchronization are redesigned using POSIX/ANSI-C Library to make the kernel compatible with Linux standard platform. To show the efficiency of the paper, it was applied to run Nomad Super Scout II avoiding obstacles detected by sonar sensor array.

우리나라 건설업체의 원가기획 적용실태에 관한 연구

고성효,서현진,고성호 제주대학교 관광산업연구소 2001 産經論集 Vol.15 No.1

유머광고에 대한 연구

고창균,신현신 京畿專門大學 1997 京畿專門大學 論文集 Vol.- No.25