莞島 및 甫吉島(全南 莞島郡)에 있어서 肺吸蟲感染의 疫學的 調査硏究

安泳謙,韓載琴,鄭正鉉 최신의학사 1979 最新醫學 Vol.22 No.11

척추 주위근의 단면적과 등척성 요추부신전 근력간의 상관 관계

권정이,이강우,김현숙,김종문,안중모 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.2

안면비대칭 진단을 위한 하악골 3차원영상 계측기준치에 관한 연구

안정순,이기헌,황현식 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.2

기존의 2차원적 진단자료는 상의 확대 및 왜곡으로 인해 형태나 크기의 정량적 평가시부적절한 결과를 야기할 수 있어 안면비대칭의 정확한 진단과 치료계획 수립을 위해서는 3차원영상 진단의 도입이 필요하다. 본 연구는 안면비대칭 진단시 3차원적 분석에 도움이 되는 기준자료를 얻고자 정상교합자를 대상으로 하악골 3차원영상 계측항목의 평균값과 좌우차이의 정상범주를 알아보기 위하여 시행되었다. 뚜렷한 안면비대칭을 보이지 않는 성인 정상교합자 남녀 30명씩 총60명을 대상으로 두경부 전단화단층사진을 촬영한 후 컴퓨터 프로그램을 이용한 각각의 단면 촬영영상 정보를 이용하여 3차원 입체영상을 재구성한 다음, 하약골 비대칭시 좌우차이를 보일 수있는 계층항목 ramus length를 나타내는 6개 condyla neck length를 나타내는 1개, mandibular body length를 나타내는 8개 등 15개의 거리 계층항목과 gonial angle을 나타내는 4개, frontal ramal inclination을 나타내는 2개, lateral ramal inclination을 나타내는 2개 등 8개의 각도계층항목. 총 23개의 계층항목을 설정한 후, 좌측과 우측을 구분하여 컴퓨터 상에서 3차원계측치를 구하고 좌우차이값을 산출하였다. 본 연구결과 얻어진 정상교합자의 하악골 3차원영상 계층항목의 좌우차이값은 안면비대칭 환자의 진단 기준치로 유용하게 사용될 수 있을 것이다. For an accurate dlagnosis and treatment planning of facial asymmetry, the use of 3-dimensional(3-D) image is indispensable. The purpose of this study was to get standard data for the 3-D analysis of facial asymmetry.Computerized tomography(CT) was taken in the 60 normal occlusion individuals (30 male, 30 female) who did not have any apparent facial asymmetry. The acquired 2D CT DICOM data were input on a computer, and the reformatted 3-D images were created using a 3-Dimage software. Twenty three measurements were established in order to evaluate asymmetry:15linear measurements (6 for ramus length, 1 for condylar neck length, and 8 for mandibular body length) and 8 angular measurements (4 for gonial angle, 2 for frontal ramal inclination, and 2 for lateral ramal inclination). The right and left difference of each measurement was calculated and analyzed. Itis suggested that the right and left differences of the measurements obtained from the study could be used as references for the diagnosis of facial asymmetric patients.

안면비대칭에 대한 주관적 인지도와 정모두부방사선사진 분석치의 연관성

안정순,황현식 대한치과교정학회 2001 대한치과교정학회지 Vol.31 No.5

본 연구는 환자의 비대칭 인지도에 영향을 미치는 정모두부방사선사진 계측치를 알아보기 위하여 시행하였다. 전남대학교병원 교정과에 내원한 환자 중 정모두부방사선사진 촬영이 필요한 12세 이상의 환자 100명을 대상으로 "본인의 얼굴이 좌우 비대칭이라고 생각하고 있는가" 를 물어보아 비대칭 인지 정도에 따라 5개 군(아니다, 아니라고 생각한다, 모르겠다, 비대칭이라고 생각한다, 분명히 비대칭이다)으로 분류하였다. 각 대상자의 정모두부방사선사진 투사도에서 계관(crista galli)과 전비극첨(anterior nasal spine)을 연결한 선을 기준으로 하여 비대칭 정도를 나타내는 9개의 선 계측치와 4개의 각도 계측치를 비교분석하여 다음과 같은 결과를 얻었다. 1.Menton의 변위와 상ㆍ하악 정중선차이가 클수록 안면비대칭에 대한 본인의 인지도가 높음을 알 수 있었다. 2."모르겠다" 라고 응답한 군의 모든 계측치는 "아니다", '아니라고 생각한다" 군과 통계적 유의차를 보이지 않았다. 3."비대칭이라고 생각한다" 라고 응답한 군의 모든 계측치는 "분명히 비대칭이다" 군과 통계적 유의차를 보이지 않았다. 이상의 결과는 안면비대칭에 대한 환자 본인의 인지 정도를 불어보는 것이 교정진단에 도움이 됨을 시사하였다. This study was aimed at how posteroanterior cephalometric measurements affect the perception of the patient about his/her facial asymmetry. One hundred orthodontic patients, over the age of 12, who required a posteroanterior cephalogram in the Department of Orthodontics of Chonnam National University Hospital were used as the subjects. They were asked if they thought their faces were asymmetrical. Their responses were classified into 5 groups based on the level of asymmetry as follows : Definitely No, Probably No, Don't Know, Probably Yes, and Definitely Yes. Nine linear and four angular measurements from each posteroanterior cephalometric radiographs were analysed on the standard of the line between crista galli and anterior nasal spine to show the extent of asymmetry. Through this comparative study, the following results were obtained. 1.As the deviation of menton and the midline discrepancy of the upper and lower jaws were greater, the perception of patients about their facial asymmetry was higher, 2.All the measurements from the group "Don't Know" showed no statistical difference from those of the groups "Definitely No" or "Probably No." 3.All the measurements from the group "Probably Yes" showed no statistical difference from those of the group "Definitely Yes."

수복재료가 5급 복합레진 수복물의 응력분포에 미치는 영향에 관한 3차원유한요소법적 연구

안형렬,김현철,허복,박정길 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.1

임상에서 5급 와동의 형태 중에 흔히 발견되는 혼합형 (교합면 쪽은 쐐기형 이고 치경부 쪽은 접시형)의 와동이 형성된 상악 제 2 소구치에 170 N의 하중을 가했을 때, 수복 전 · 후에 나타나는 와동변연부와 와동벽, 그리고 수복물의 응력 분포를 3차원적 유한요소 분석법으로 조사한 결과 다음과 같은 결론을 얻었다. 1. 수복 전에 비해 수복 후 굽힘응력이 집중되는 백악법랑경계와 와동저 선각부위에서 응력이 감소하였다. 2. 수복 전에 비해 수복 후 교합면과 치경부의 와동변연과 와동벽에서는 응력이 증가하였다. 3. 혼합형 레진과 혼합형 / 흐름성 레진으로 수복하였을 때 흐름성 레진으로 수복한 경우보다 백악법랑경계와 와동저 선각부위에서 응력이 더 감소하였다. 4. 혼합형 레진과 혼합형 / 흐름성 레진으로 수복하였을 때 흐름성 레진으로 수복한 경우보다 교합면과 치경부의 와동 변연과 와동벽에서 응력이 더 증가하였다. The purpose of this study was to analyze the stress distribution aspect of unrestored and restored combined shape (wedge shape occlusally and saucer shape gingivally) class V cavity, which found frequently in clinical cases. A maxillary second premolar restored with a combined shape class V composite restorations were modeled using the three dimensional finite element method. Static occlusal load of 170 N was applied on lingual incline of buccal cusp at the angle of 45˚ with the longitudinal axis of the tooth. And three dimensional finite element analysis was taken by ANSYS (Version 6.0, Swanson Analysis System Co., Houston, U.S.A) program which represent the stress distribution on unrestored and restored cavity wall and margin. The conclusions were as follows. 1. Compared to the unrestored cavity. Von Mises stress at the cementoenamel junction and line angle of the cavity base were reduced and in restored cavity. 2. Von Mises stress at the occlusal and cervical cavity margin and wall were increased in restored cavity in comparison with the unrestored cavity. 3. In the hybrid and hybrid/flowable composite resin restoration. Von Mises stress at the cementoenamel junction and line angle of the cavity base were reduced more than in the flowable restoration. 4. In the hybrid and hybrid/flowable composite resin restoration. Von Mises stress at the occlusal and cervical cavity margin and wall were increased more than in the flowable restoration. 〔J Kor Acad Cons Dent 31(1):20-29, 2006〕

안면비대칭에 대한 주관적 인지도와 정모두부방사선사진 분석치의 연관성

안정순,황현식,김창수,김경근 전남대학교 치의학연구소 2001 구강과학 Vol.13 No.3

This study was aimed how posteroanterior cephalometric measurements affect the perception of the patient about his/her facial asymmetry. One hundred orthodontic patients, over the age of 12, who required a posteroanterior cephalogram in the Department of Orthodontics of Chonnam National University Hospital were used as the subject. They were asked if they thought their faces are asymmetrical. Their responses were classified into 5 groups based on the level of asymmetry as follows : Definitely No, Probably No, Don't Know. Probably Yes, Definitely Yes. Nine linear and four angular measurements from each posteroanterior cephalometric radiographs were analysed on the standard of the line between crista galli and anterior nasal spine to show the extent of asymmetry. Through this comparative study, the following results were obtained. 1. As the deviation of menton and the midline discrepancy of the upper and lower jaws were greater, the perception of patients about their facial asymmetry was higher. 2. All the measurements from the group "Don't Know" showed no statistical difference with those of the groups "Definitely No" or "Probably No." 3. All the measurements from the group "Probably Yes" showed no statistical difference with those of the group "Definitely Yes." The above results suggest that it may be helpful for the orthodontic diagnosis to ask patients' perception of their own facial asymmetry.

보건관리 대행사업장 근로자에서 건강증진에 대한 5년 사이의 지식, 태도 및 실천의 변화

임현우,김정아,안병용,박정일,구정완,이강숙 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

Before and after conducting the health promotion program by group occupational health service during 5 years, we surveyed knowledge, attitude and practice about general health (30 items) and occupational health(30 items) among 25 small and medium scale industry workers(before: 355 workers, after: 279 workers) for evaluation of effectiveness. The scores of knowledge for smoking, drinking, cholesterol, mental stress, management of hypertension, and risks in younger or women workers were significantly increased after conducting group occupational health service. The scores of attitude for controlling of fatty food consumption and cleaning workplace and bathing for health and that of practice for taking the periodic health examination and checking blood pressure were significantly increased but most of items in attitude and practice didn't be changed after services. According to sex, the scores of men were significantly increased in knowledge of general health, but there were not significant differences in age, job status and work duration group. In conclusion, through the group occupational health service during 5 years, only the scores of knowledge in general health were increased. It suggested that the effective program which can change workers' attitude and practice for health promotion, should be developed and conducted in small and medium scale industry workers.

말티즈개의 구강에서 발생한 골육종

정윤경, 조현예, 이상섭, 김미희, 이계리, 변현섭, 장동우, 안병우 충북대학교 동물의학연구소 2007 Journal of Biomedical and Translational Research Vol.8 No.1

본문참고

대퇴동맥을 통한 경피적 관동맥 중재시술 환자의 천자부위 지혈을 위한 Angioseal^(�) 사용과 고식적 용수 압박법의 비교 : 전향적 연구

김용훈,권현철,김필호,안석진,유철웅,최진호,이상철,김준수,김덕경,전은석,이상훈,홍경표,박정의,서정돈 대한내과학회 2004 대한내과학회지 Vol.66 No.5

목적 : 경피적 관동맥 중재술은 최근 양적 및 질적으로 급격한 발전을 보였지만 시술 시 천자부위의 혈관 합병증은 아직 해결해야 할 문제점이다. 저자들은 대퇴동맥을 통한 경피적 관동맥 중재술을 환자에게 천자부위 지혈을 위한 혈관폐쇄기구인 안지오실의 안전성과 유용성을 고식적인 용수 압박법과 비교 연구하고자 하였다. 방법 : 2002년 4월부터 2003년 5월 사이에 삼성서울병원 심장혈관센터에서 대퇴동맥을 통한 경피적 관동맥 중재술을 성공적으로 시행한 200명의 환자(안지오실 사용군: A군, 100명, 고식적 용수압박법 사용군 B군, 100명)를 대상으로 시술 후 주요 합병증 및 경한 합병증, 지혈 후 환자가 자리에 앉기까지의 시간, 보행개시 가능시간, 총 재원 기간과 시술 1주 후의 합병증을 전향적으로 조사하여 비교 연구하였다. 결론 : 두 군에서 연령, 성별, 기저질환, 심혈관 질환의 위험요소, 시술의 종류, 시술 중 사용한 헤파린의 양, clopidogrel의 양, ticlopidine의 양, 지혈 시 수축기와 확장기혈압, ACT (activated clotting time)는 차이가 없었다. A군이 B군에 비해 시술 후 자리에 앉기까지의 시간 (A군: 4.3±0.3시간, B군: 13.7±0.8시간, p=0.004) 및 보행개시까지의 시간(A군: 6.8±0.5시간, B군: 18.8±2.1시간, p=0.013)이 유의하게 짧았다. 시술 후 주요 합병증은 두군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 A군에서 유의하게 적었다(A군: 28명, B군: 19명, p=0.003). 반상출혈의 경우는 A군에서 유의하게 낮았지만(A군: 3명, B군: 12명, p=0.01), 혈종, 출혈의 발생은 두군간에 차이가 없었다. 총 재원기간에는 두 군간에 차이가 없었다(p=0.239). 시술 1주 후 경과관찰에서 주요합병증은 역시 두 군 모두에서 관찰되지 않았으며, 경한 합병증의 전체발생은 두 군에서 차이가 없었다(A군: 15명, B군: 13명 p=0.418), 반상출혈의 빈도는 차이가 없었지만 혈종의 발생은 A군에서 더 낮았다(A군: 2명, B군:6명, p=0.004). 두 군 모두에서 출혈은 발생하지 않았다. 결론 : 대퇴동맥을 통한 경피적 관동맥 중재술을 시행한 환자에서 안지오실의 사용은 고식적 용수 압박법에 비해 환자의 침상 안정시간을 줄여 조기 활동개시가 가능하게 하였으며 국소합병증의 위험도를 일부 낮추어, 시술에 따른 환자의 불편을 현저하게 감소시킬 수 있다고 할 수 있을 것으로 기대된다. Background : Although the number and the quality of percutaneous coronary intervention have been recently increased dramatically, the vascular complication at puncture site is still the major cause of patients' morbidity. We evaluated the safety and efficacy of newly of newly-developed collagen-based arterial closure device, Angioseal after transfemoral percuatenous coronary intervention. Methods : This study was designed as a prospective single center non-randomized comparative study. A total 200 patients undergoing transfemoral percutaneous coronary intervention were enrolled between April 2002 and May 2003. They were divided into two groups; Angioseal group (group A, n=100) and manual compression group (group B, n=100). The baseline clinical and angiographic characteristics were reviewed. The time to sit up, the time to ambulation, the duration of hospital stay, major and minor vascular puncture site complications were monitored. The patients were followed-up for 1 week after procedure by telephone. Results : The baseline clinical characteriwtics, clinical diagnosis, cardiocascular risk factors, typesof procedure, doses and numbers of anticoagulants were similar between two groups. The blood pressure and activated clotting time were also similar. The time to sit up (group A: 4.3±0.3 hours, group B: 13.7±0.8 hours, p=0.004) and the time to ambulation (group A: 6.8±0.5 hours, group B: 18.8±2.1 hours, p=0.013) were shorter in group A. No major vascular complications were noted. The incidence of hematoma and bleeding were not significantly different between two groups. The incidence of ecchymosis, however, was significantly lower in group A (group A:12%, group B: 3%, p=0.001) The duration of gospital stay was similar between groups. During 7 days of follow-up period incidence of hematoma was significantly lower in group A (p=0.004). Although the incidence of ecchymosis was not significantly different between two groups. Conclusion : The angioseal may be associated with earlier ambulation and less patients' morbidity with low incidence of local complication rate compared to manual compression after transfemoral percutaneous coronary intervention.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.