국소성 분절성 사구체 경화증의 완전 관해 후 발병한 IgA 신병증 1예

임현민,김현정,박민석,주혜원,최원,김상현,박원도 인제대학교 2006 仁濟醫學 Vol.27 No.-

We report a rare case of primary glomerular disease with IgA nephropathy in a 43-year old man. 7-years ago, he was diagnosed with minimal change nephrotic syndrome. After treatment with steroid for 1-year, azotemia and proteinuria were improved. But, nephrotic range proteinuria was relapsed within 1 week after cessation of steroid. Renal biopsy revealed focal segmental glomerulosclerosis, and achived a complete remission with the use of steroids and cyclophosphamide. Then, he was followed up with normal renal function for 4-years. On admission, the patient showed generalized edema and marked proteinuria. In 3rd renal biopsy, mesangial proliferative glomerulonephritis with diffuse global sclerosis was observed. Electron microscopy showed electron-dense deposit on the mesangium with slight mesangial proliferation, and immunofluoroscence microscopy showed granular deposits of IgA and IgM. These features were consistent with IgA nephropathy, different from results of previous biopsies. The pathogenesis of IgA nephropathy occurred with primary FSGS is not clear, as well as treatment. Now, proteinuria is improving, steroid and cyclophosphamide are probably useful for the disease.

Inhibitory Effect of Clavicepitaceae on Serotonin Release out of Human Platelets and Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

We have investigated the effects of hypha-water extracts (HWE), fruit body-water extracts (FWE) and cordycepin from Cordyceps militaris on serotonin release out of human platelets and human platelet aggregation. HWE and FWE inhibited the release of [^(3)H]-serotonin from human platelet stimulated by thrombin (2 U/ml) or collagen (20 ㎍/ml) in a dose-dependent manner. Furthermore, cordycepin, a major component of Cordyceps militaris, inhibited the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. These results suggest that cordycepin containing in HWE and FWE may inhibit the serotonin release by suppressing the collagen-induced human platelet aggregation. Accordingly, our data demonstrate that HWE and FWE containing much cordycepin might have antithrombotic and antimigrainous functions.

갑상선기능저하증 이환견에 대한 치료 증례

김혜원,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

A 10-year-old, male, poodle dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University because of continuous cough and cardiomegaly. Weight gain, lethargy, unwillingness to exercise and decreased activity was revealed on history. Obesty and alopecia was also observed on physical examination. Hypercholesterolemia and increased ALP was revealed on blood exam. So, evaluation of thyroid gland function was performed and cTSH concentration was increased. tT4 and fT4 concentrations was decreased. Results of a history, physical examination, blood exam, and thyroid gland fuction test support a diagnosis of hypothyroidism. Initial therapy with sodium levothyroxine was indicated. On 32 days after treatment of hypothyroidism, clinical signs was relieved and cTSH concentration was decreased, tT4 and fT4 concenctrations was increased.

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

홍삼류의 섭취가 비만과 혈중 지질의 상호관계에 미치는 영향

박화진,이정희,이소진,함혜선,조현정,임창률,유영빈,박기현 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.4

비만은 동맥경화의 위험인자로서 혈중에 triglyceride의 농도를 종가시키고, 상대적으로 HDL-Cholesterol의 농도를 감소시킴과 동시에 수축기 혈압을 상승시킨다. 본 연구에서 홍삼제품류를 4년 또는 5년 동안 복용해 온 건강한 사람 (ginseng군)과 홍삼제품을 복용하지 않은 건강한 사람 (control군)을 대상으로 하여 신체 계측치로부터 비만지수를 구하고 이것과 혈중의 triglyceride (TG)농도, TG/HDL-Cholesterol ratio 및 수축기 혈압과의 상호관계를 연구한 바, ginseng군에서는 대조군에 비해 혈중의 TG 농도가 일정하게 유지되었고, TG/HDL-Cholesterol ratio 및 수축기 혈압도 일정하게 유지되었다. 이러한 현상은 ginseng군에서 기호품으로 alcohol을 섭취하거나, 흡연을 한 경우에도 상관없이 일정하게 유지 되었다. 이 결과는 홍삼제품류를 장기 복용하면 비만의 저하 및 고혈압 또는 동맥경화의 위험인자가 억제될 수 있고, 결론적으로 비만, 고혈압 및 동맥경화를 예방할 수 있을 것으로 추정한다. Obesity is the risk fcactor of atherosclerosis and not only increases triglyceride concentration in blood but also decreases relatively the ratio of TG to HDL-Cholesterol in blood. In case of obesity, systolic blood pressure is also increased in responding the increase of TG in blood. Index of obesity in red ginseng-taking group (ginseng group) was lower as compared with non-red ginseng-taking group (control group). The TG concentration, the ratio of triglyceride to HDL-cholesterol in blood and systolic blood pressure were decreased in the subjects of ginseng group compared with that in control group. It is inferred that long-term intake of ginseng products may help to prevent the risk of atherosclerosis and obesity.

마케팅 리서치에서 다중측정방법에 관한 실증적 연구

박혜정,김혜정,이영주,임숙자 服飾文化學會 2002 服飾文化硏究 Vol.10 No.6

Qualitative research is a method widely used in marketing research However. the method has seldom been used in fashion marketing research in Korea. The purpose of this study was to prove that using both qualitative and quantitative research methods in main stage is much useful than using qualitative research method only in exploratory stage. Qualitative data were gathered by conducting Focus Group Interview(FGI) with 48 college students. Quantitative data were gathered by surveying college students, and 487 questionnaires were used in the statistical analysis. The data were analyzed using content analysis. mean. standard deviation, and t-test. As a result, FGI. one of the tools used in qualitative research methods, was proved to be useful in revealing consumers' deep emotional needs as well as purchase motives. FGI also revealed information which quantitative research method tools such as survey could have missed. Therefore. it is best to use multiple methods-simultaneous use of quantitative and qualitative methods-to understand fast changing consumers' needs and Purchase motives

후두절제술을 시행받았던 환자에게 기관절개부위로 흡인된 기관지내 금속관의 굴곡성 기관지내시경을 이용한 제거 1례

임건일,박혜정 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Most of foreign body aspiration is done via oral cavity. When the foreign body is found in airway, they try to remove it by rigid or flexible bronchoscopy. A 79-year-old man was admitted with foreign body aspiration via tracheostomy site. Chest X-ray showed metallic tube in lower trachea. We did flexible bronchscopy and removed it. After removal, patient's symptoms were relieved. We report a case of foreign body removal by flexible bronchoscopy with brief review of the literature.

경북 구미시 종합병원에서 진단된 토착형 삼일열 말라리아 21예

임건일,박헤정 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Background: Malaria is estimated to have a worldwide incidence of more than 100 million clinical cases and approximately 1 million deaths per year. Korea, although previously known as an endemic area of tertian malaria(Plasmodium vivax), has been considered free from malaria as there had been no report on indigenous cases since 1984. However, since the reemergence of indigenous vivax malaria in 1993, the number of cases of malaria have recently increased. We analyzed 21 cases of malaria who were treated in Soonchunhyang Gumi hospital with regard to epidemiology, clinical manifeastations, and laboratory findins. Methods: We retrospectively analyzed data of 21 cases of malaria treated in our hospital. Results: All cases were indigenous. All patients had fever. Peripheral blood smear revealed Plasmodium vivax. Paju-gun/Munsan(8 cases) was the most prevalent area. 4 cases were anemia(hemoglobin <10 g/dL) and 15cases were thrombocytopenia ( platelet < 100,000/㎕). Conclusion: In patients, the most common labaratory findings were thrombocytopenia. As cases of indigenous malaria in Korea are increasing, early diagnosis, treatment, and prevention of malaria are important.

데이터베이스의 상태변이 제어를 통한 일관성 유지

임채명,이혜명,박동규 순천향대학교 부설 산업기술연구소 1997 순천향 산업기술연구소논문집 Vol.3 No.1

Several researchers have proposed method which incorporate dynamic properties of data into database in order to represent the semantics of the real world. Such researches have focused only on modeling for database states and transactions. And transaction schemes which they have proposed have preconditions within them. In this case, whenever behavioral environments are changed, transaction schemes must be modified, too. They are inflexible and inefficient schemes. However, there have been only a few efforts trying to separate preconditions from transaction schemes. In this paper we propose modalities of database state transitions and present methods for efficient management of them. For the efficient transition control of database state, we separate preconditions from transaction schemes and design them using active rules. Transition control method is used to determine whether a certain transaction(or transition) can be executed or not and to maintain the consistency of databases.

HPLC/ELSD에 의한 Diterpenoid Alkaloids의 분석

임미애,이주선,백승경,최혜영,박유신,이한선,육창수,오세욱 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-