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      • 간세포암종에 대한 간동맥 화학색전술 후 발생한 급성호흡곤란증후군

        조윤원,이정미,최자윤,유동훈,차라리,오혜원,김홍준,민현주,김현진,정운태,이옥재,하창윤,이선영 이화여자대학교 의과학연구소 2013 EMJ (Ewha medical journal) Vol.36 No.1

        Transcatheter arterial chemoembolization (TACE) has become an effective alternative treatment strategy for patients with inoperable hepatocellular carcinoma (HCC). Although TACE is relatively safe, acute respiratory distress syndrome associated with pulmonary lipiodol embolism is a rare and potentially fatal complication. We report a rare case of acute respiratory distress syndrome after TACE for inoperable HCC. A 75-year-old man, with huge HCC in right lobe, was treated by TACE for the first time. Seven hours after uneventful TACE procedure, he felt dyspneic and his oxygen saturation recorded by pulse oximetry (SpO2) fell to 80% despite of applying non-rebreathing mask. He underwent mechanical ventilation with a protective ventilatory strategy. We experienced a case of acute respiratory distress syndrome after TACE for HCC.

      • 무산소성 운동이 혈청 지질 농도 및 면역세포 반응에 미치는 영향

        조영주,변재철,홍석민 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

        The purpose of this study was to determine serum lipids and immune responses on the anaerobic exercise. Serum total cholesterol, HDL-C, LDL-C and plasma triglyceride, percentages of WBC and their subsets, natural killer cells were evaluated between before and after the anaerobic power. All subjects were high trained male athletes (19-24 years of age). Results were expressed as mean and standard deviations. One-way ANOVA repeated measure was used to compare the all parameters between before and after the anaerobic power test. All significant differences were set at α=.05. In this study, comparison of anaerobic power(Nm/%BW) was higher in soccer players than ssirum and judo players (p<.05). The percentage of WBC, monocyte, eosinophil and basophil were no significant differences between before and after anaerobic exercise. There were increased on neutrophil, lymphocyte after anaerobic exercise in three groups. (p<.01, p<.001, respectively). Also, there were significant differences on T cell, B cell, NK cell between before and after anaerobic exercise (p<.001).

      • 김치 유산균인 Lactobacillus sp. JJ-2001이 생산하는 Bacteriocin에 관한 연구

        조영배,조우제,조영임,이은주,김성구,전홍기 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

        The microorganisms producing bacteriocin from kimch were screened, and among them,a strain showing the highest bacteriocin activity and stability was isolated. Based on the taxonomic characteristics of its morphological, cultural and physiological properties, the isolatef strain was characterized as Lactobacilius sp..To identify optimal conditions for the growth and the production of bacteriocin from the isolated strain,nutrient source, initial pH, and culture temperature were evaluated. Physiochemical properties of bacteriocin was also investigated. The potimal condition for the production of bacteriocin and the cell growth was obtained at 2% glucose, 1% beef extract as organic nitrogen source,1%(NH_4)_2SO_4 as inorganic nitrogen source,and 0.1% Tween 80. The isolated strain showed the maximum growth at 25℃. The inhibitory range of its antimicrobial substance aginst gram positive bacteria was marrow and its inhibitory activity was maintained between pH3.0 and pH8.0. The antimicrobial activity of bacteriocin from the isolated strain was stable at 50℃.

      • 초음파 비파괴 검사기법에 의한 용접결함 분류성능 비교

        김재열,유신,김창현,송경석,양동조,김유홍 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

        In this study, we made a comparative study of backpropagation neural network and probabilistic neural network and bayesian classifier and perceptron as shape recognition algorithm of welding flaws. For this purpose, variables are applied the same to four algorithms. Here, feature variable is composed of time domain signal itself and frequency domain signal itself. Through this process, we comfirmed advantages/disadvantages of four algorithms and identified application methods of four algorithms.

      • KCI등재

        자유학기제 연구학교의 수업과 교육활동의 특징 분석

        이재창,홍후조,김미진,임재일 이화여자대학교 교과교육연구소 2014 교과교육학연구 Vol.18 No.4

        본 연구에서는 2013년도에 실시한 자유학기제 연구학교 42개교의 운영 보고서를 분석함으로써 시험이 없는 교육의양상을 살펴보았다. 연구결과 자유학기제는 첫째, 공통과정 기본교과 수업방식의 대부분이 학생주도적인 활동으로이루어지고 있었다. 둘째, 진로탐색 활동이 다양화되고 심화되었다. 셋째, 자율과정은 주입식 교육에서 벗어나 다양한 활동을 제공하고 있었다. 넷째, 학교는 지역사회와의 인적․물적 자원과 연계 지도 인프라 구축을 통해 연계 지도를 하고 있었다. 반면, 자유학기제의 여러 가지 문제점도 발견할 수 있었다. 우선, 자유학기제의 차별화된 교육활동은 중학교 1학년내, 그리고 학년 간의 교육계획에 있어서 혼란을 야기하고 있었다. 또한, 자유학기제 해당 학생들에게만 편중된 교육을 제공하여 타 학년과의 위화감과 소외감도 조성하고 있었다. 그리고 진로탐색 활동의 경우 지적인 탐색과 진로 검사와상담 ,체험을 통한 체득 등 탐색하고 체득하는 활동에만 편중되어 있었다. 끝으로, 자율과정의선택 프로그램 활동, 동아리 활동등 다양한 범주들이 중복되고 비체계적이라는 문제가 발견되었다. 이러한 문제점을해결하고자 본 연구에서는 첫째, 교육과정 계획 단계부터 운영에 이르기까지 교사들이 공동으로 연구하여 자유학기제를 운영하는 학기와 일반 학기의 격차를 줄여야 한다. 둘째, 자유학기제 시행으로 인한 긍정적인 효과들을 타 학년에도적용할 필요가 있다. 셋째, 진로윤리교육의 확대를 통해 균형 잡힌 진로탐색 활동 전개를 주문하였다. 넷째, 자율과정 중 성격과 내용 면에서 서로 중복된 범주들을 체계적으로 정비하여야 할 필요가 있음을 강조하였다 This research analyzed the reports on Free Semester System of 42 pilot schools, which do not have any assessment, in order to inspect the new ways of instructions and educational activities. The results are as follows; First, most of the basic subjects instructions on common courses were student-centered activities. Second, career exploration activities were diversified and enhanced. Third, optional courses provided various activities which fitted students’ interests and needs. Fourth, all of the educational necessities were provided for the pilot schools by the local community. However, Free Semester System’s new curriculum causes some confusion in the operation of educational plans, not only for first grade students but also second and third grade students. nbalanced new educational experiences among Free Semester System students and other grade students cause a sense of incongruity and alienation. In addition, career exploration activities put too much emphasis on intellectual exploration, career-test and career-counselling, and career related experience. Finally, optional courses programs were often redundant and required organization. uggestions to solve these problems are as follows; First, School staffs should build the school curriculum together from planning to management in order to decrease the gap between Free Semester System and general semester system. Second, the positive effect of Free Semester System should be applied to other grades to solve the sense of incongruity and to increase the quality of education. Third, career exploration activities need to be balanced by increasing the learning of vocational ethics. Fourth, optional courses have to be re-arranged to be more systematic. If additional research is conducted in accordance with the suggestions made by this research, Free Semester System will regain the authentic educational role of middle school, which is different from that of junior high school, and will play a role as the bridge of lementary school’s basic education and high school’s career-based education.

      • KCI등재
      • 구조물의 비접촉 비파괴 검사를 위한 레이저 초음파법 적용

        김재열,송경석,양동조,김유홍 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

        The defects evaluation of the interior and the surface would be considered as vital characteristics in predicting the total life span of the steel structure. More importantly, the understandings in the interior composite of welding zone and the notifications in the presence, the formation, and the positioning of the non-metallic inclusion are necessary as well, since there were signs of relatively high defect frequency presented in the welding zone. The ultrasonic testing is a highly recommended technique chosen from among other techniques because of variety of advantages in conducting the non-destructive testing for the welding zone. However, the ultrasonic testing had technical disadvantages referred as followings; the problems due to the couplant between the PZT and the specimen, the formations that were miniature and complex, the moving subject, and the high temperature surrounding the specimen. This research was conducted to resolve the technical disadvantages of the contact ultrasonic testing by studying the non-contact ultrasonic testing where the ultrasonic waves were transferred by the laser, and revealing the specimen defects at its interior part and its surface part. The ultimate goal of this research was to develop a non-destructive evaluation applying the laser manipulated ultrasonic method for the steel structure

      • KCI등재
      • 瀉白散의 肥滿細胞 嫫介性 炎症性 細胞活性物質 分泌 抑制 效果

        이병주,신조영,이시형,홍재의,박병민,이승언 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

        Ocjective : Sabaeksan has been used for the purpose of prevention and treatment of bronchial asthma and allergic asthma in korea. Methods : To investigate the biological effect of Sabaeksan, the author examined cytotoxicity and inflammatory cytokines secretion with human leukemic mast cell line, HMC-1. HMC-1 was stimulated with phorbol 12-myristate 13-acetate (PMA) and calcium ionophore A23187. Sabaeksan by itself had no effect on viability of HMC-1. Result : The effects of Sabaeksan on the secretion of tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-6 from HMC-1 were evaluated with enzyme-linked immunosorbent assay. Sabaeksan (1 mg/㎖) inhibited PMA plus A23187-stimulated TNF-α and IL-6 secretion, by 43.86 ± 5.26%, 56.39 ± 3.65%, respectively. Sabaeksan also inhibited the NF-κB (p50/p65) expression. Conclusion : Taken together, these results suggest that Sabaeksan inhibit the production of inflammatory cytokines in HMC-1 cells through blockade of NF-κB activation.

      • SCIESCOPUSKCI등재

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