브루셀라균에 노출된 미생물 검사실 직원들에 대한 예방적 항생제 요법과 혈청학적 추적검사

이창섭,이혜수,이재현,박진희,최영실,황규잠,이흥범 대한감염학회 2008 감염과 화학요법 Vol.40 No.2

The aerozolization is one of possible Brucella transmission mechanisms, particularly in air-borne exposed laboratory workers. In this study, seven laboratory workers were potentially exposed to B. abortus via aerosols. Two laboratory workers who sniffed an agar plate several times were considered to be at high risk for acquiring the disease, 5 workers who did not work directly with the strain were be considered at low risk of infection. Prophylactic antibiotics of doxycycline 200 mg/day and rifampin 600 mg/day were offered for 6 weeks in high risk workers and 3 weeks for low risk workers respectively. Enrolled workers were advised to check for serological testing of Brucella species every 3 weeks during a total period of 12 weeks. Compliance with taking medicine was 57.1% (4/7) and compliance for completing the serological tests was 85.7% (6/7). None of the laboratory workers developed clinical disease or tested positive serologically during 3 months of seroloaical testing and 1 year of clinical follow-up.

FET형 반도체 마이크로센서 개발(Ⅱ)

손병기,이흥락,박이순,조진호,이성필,최평,서화일,고성택,박재윤,서장수,김창수 경북대학교 센서기술연구소 1994 연차보고서 Vol.1994 No.-

현재 의료진단, 화학공정의 모니터링이나 환경공학적 감시 및 제어 등의 분야에서 사용되고 있는 기존의 센서는 고가이며 용적이 클 뿐만 아니라 분석시간이 길고 사용하기 까다로운 것 등 여러 가지 문제점이 있다. 또한 측정환경에 영향을 주지 않을 만큼 충분히 작으며 빠른 분석시간을 가진 센서를 필요로 하고 있다. 본 연구에서는 기존의 센서들의 난점을 극복할 수 있는 새로운 형태의 FET형 전해질(electrolyte : H^+, K^+, Ca^2+, Na^+)분석 시스템, 용존가스(O_2, CO_2)분석 시스템의 개발을 중점적으로 추진하며, FET형 압력센서, 습도센서, 방사형 온도센서 등의 개별 FET형 센서에 관한 연구도 병행하고자 한다. Recently various kinds of sensors have been developed, being applicated to their own purpose. There are lots of difficulties to apply them to measurements in which the real-time monitoring is required without disturbing the surrounding environment. FET type semiconductor sensors, fabricated by the semiconductor integration technologies, have many advantages for their miniaturization, standardization, mass-production and in vivo/in situ monitoring. They also hold a very proper configuration for multi-functional sensors or integrated smart sensors, and wide availability by forming various kinds of physical or chemical sensing materials onto their sensing gates.

유통 한약재의 이산화황 함유량에 관한 연구

신영민,조태용,이광수,김성훈,박흥재,임동길,이창희,김우성,채갑용,이영자,최수영 한국환경과학회 2004 한국환경과학회지 Vol.13 No.12

This study was investigated the residual contents of sulfur dioxide on the 373 kinds of herbal medicine distributed from Korea, China, and Japan. A modified Monier-Williams method was described for the determination of SO₂ contents in herbal medicines. The residual contents of SO₂ were not detected at 221 products(59.8%) in total 373 products. Regardless of region, SO₂ contents were not found at Farfarae Flos, Zizyphi Spinosi Semen, Castanea crenata, and Strychni Ignatii Semen. But it's found at Asparagi Radix, Codonopsitis Radix, Lilii Bulbus, and Kaempferiae Rhizoma of every region collected the samples. Also, SO₂ contents were not detected at the herbal medicines which collected cultural fields of dometic. SO₂ contents ranged 11~3990 mg/kg(mean 152 mg/kg) at domestic samples, 11~3440 mg/kg(mean 603 mg/kg) at imported samples. After treated with water wash and hot water extraction, the reduction rates of sulfur dioxide were appeared with 24.4%~68.7% and 83.8%~100.0%, respectively. These data will be used to establish a criteron of residual sulfur dioxide in herbal medicines.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

韓國 都市 어린이와 農村 어린이의 TV 受容形態와 價値志向에 關한 比較硏究 : TV 受容形態가 價値志向에 미치는 영향을 中心으로 with Focus on the Effects of TV on Value Formation

李相回,朴興壽 연세대학교 대학원 1977 延世論叢 Vol.14 No.1

The findings of this study are summarized in the following. First, it turns out as a result of the research that the Korean children in general have internalized anti-communist value orientation. The urban orientation, a desire to use urban age cohorts as their role model, on the part of the rural children, tends to be promoted by parents and information disseminated by mass media. Second, children in urban areas tend to be self-oriented and individualistic as compared with rural children. Their pattern of thinking is also logical. These characteristics are clearly demonstrated by children of parents with high socio-economic status. Rural children tend to select their jobs based on altruistic motivation, whereas urban children are influenced by egoistic motivation in determining their jobs. Third, the socio-economic status of parents has some influence on frequency of interaction between parents and children. The findings also show that the frequency of communication between parents and children affects to a very limited degree selection of television programs on the part of children. This may be caused by the fact that the frequency of interaction does not effectively represent the degree of parental affection given to the children. Another reason for no influence of frequency of interaction on television program selection may have derived from the fact that only a few children have answered that they do not maintain communication with their parents. Fourth, urban children watch television longer than rural children, and children in urban areas are more attracted than rural children to television programs. In general, children watch children's programs most, but urban children are more attracted to adult programs than rural children. That is, urban children watch adult entertainment programs to a great extent as compared with rural children. Fifth, relatively speaking, rural parents tend to strictly control television viewing by their children, but it is found that children both in urban and rural areas watch most of early evening programs, only with exception for late evening programs. Sixth, children do not tend to mistake hypothetical realities as shown in television for actual events that frequently take place in realities, nor do they imitate acts from television, especially behaviors that smack of anti-social nature. Seventh, affectionate as well as emotional programs continue to have impact on children for longer period of time than other programs. This influence does not have any regional difference. They tend to show immediate emotional response to such programs, but their pattern of behavior does not seem to develop into imitation. Eighth, many of children adopt television heroes as their role model, but rarely do they imitate heroes' behavior. Ninth, among Korean children, socio-economic status of parents does not have differential impact on children, whether urban or rural, in terms of pattern of viewing and television influence. However, broken family plays a vital role in television acceptance pattern. Tenth, there exists some negative correlation between hours of daily television viewing and grade point average, but contents of television programs do not seem to negatively influence grade point average.

산도를 조절한 불화석 용액의 치과 응용에 관한 연구 : 제 1 편 : 불화석 용액과 완충액에 의한 치과 수복재의 표면변화

이용근,이성재,이흥수 대한치과기재학회 1997 대한치과재료학회지 Vol.24 No.1

Topical fluoride application reduces the incidence of dental caries, and it is well known that hydrofluoric acid etches glass and ceramic. Repeated exposure of dental ceramic or composite resin to acidulated phosphate fluoride can result in material loss, surface roughening, and corresponding change of esthetic appearance. The effect of APF preparations on dental ceramic or composite restorations was reported, but the influence of fluoride solutions routinely used for mouth rinsing or topical application is unclear. And the acidity of fluoride solutions can influence the surface change of glass containing dental materials. In this study, the effect of stannous fluoride solutions and buffer solutions of different acidity on esthetic filling materials was determined. Five kinds of composite resins(AEF, HPL, POF, TPH, Z100) and two kind of glass ionomers for filling(FJT, FLC) were studied. Specimens of 8mm in diameter and 2mm in thickness were made and fine polished, after then vickers hardness and color of the specimens were measured. Five kinds of immersion solutions were used, they were distilled water(CTRL) as control, dibasic sodium phosphate buffer(SFPB) and in distilled water(SFDW). Specimens were immersed in each solution and thermocycled for 500 cycles between 5℃ and 55℃. After then, Vickers hardness and color of the specimens were measured and compared with results before immersion. From this experiment, the following results were obtained. 1. The color differences(CIELAB ΔE*) of AEF, TPH, Z100, FJT and FLC in SFPB, in most cases, significantly higher than those in other solutions(P<0.05), and those of HPL and POF in SFDW was significantly higher than those in all the other solutions(P<0.05). 2. Comparing the result in the same immersion solution, color differences(CIELAB ΔE*) of different materials in CTRL were not significantly different from each other(P>0.05), but in other cases, the results were different depending on the material and solution combinations. 3. Change of Vickers hardness after treatment of resin-modified glass ionomer in PB2.5 was significantly higher than those in all the other solutions(P<0.05), and one kind of composite significantly influenced by the acidity of fluoride solution.

쌀누룩으로 담금한 탁주 술덧의 유기산, 유리당 및 유리아미노산의 함량

이홍숙,이택수,노봉수 서울여자대학교 자연과학연구소 2004 자연과학연구논문집 Vol.16 No.-

쌀을 사용하여 만든 재래식의 쌀누룩, Aspergillus oryzae 및 Rhizopus japonicus의 개량식 쌀누룩 및 재래식 밀누룩으로 탁주를 담금하여 발효 중 유기산, 유리당, 유리아미노산의 함량을 측정한 결과는 다음과 같다. 탁주의 유기산으로 lactic acid, succinic acid, citric acid가 발효중 모든 시험구에서 확인되었고 시험구에 따라서는 malic acid, malonic acid, pyruvic acid도 확인되었다. 유기산 총량은 밀누룩구가 147.40~820.89 mg%로 가장 높았고 재래식의 쌀 누룩구는 150.80~278.40 mg%로 가장 낮았다. Lactic acid는 19.20~649.85 mg% 로 탁주 유기산의 주성분으로 발효 8일에 최대함량을 보였고 시험구중에는 밀누룩구에서 함량이 높았다. 탁주에서 측정된 glucose, fructose, maltose의 유리당 총량은 71.24~778.68 mg%의 범위였고 시험구중 재래식의 쌀누룩구에서 높은 편이었다. Glucose는 63.50~748.88 mg% 의 범위로 탁주의 유리당중 함량이 가장 높았으며 fructose, maltose의 함량은 30 mg% 이하였다. 발효 8일 탁주의 유리아미노산 총량은 재래식 쌀누룩구 430.3 mg%, AspergIllus oryzae 쌀누룩구 416.3 mg%, 재래식 밀누룩구 403.2 mg% , Rhizopus japonicus 쌀 누룩구 203.5 mg% 로 쌀을 이용한 누룩의 탁주에서 대체로 유리 아미노산 함량이 높았다. 탁주에서 alanine, glutamic acid, arginine, proline, tryptophan, leucine의 함량이 높았다. 유리 아미노산중 쌀누룩구의 탁주에서는 alanine 이, 밀누룩의 탁주에서는 tryptophan 의 함량이 가장 높았다. 퓨젤류인 n-propyl alcohol, iso-butyl alcohol, iso-amyl alcohol의 총량은 nd~704ppm 으로 재래식의 밀누룩구와 쌀 누룩구의 탁주에서 높은 편이고, 퓨젤류중 iso-amyl alcohol의 함량이 높았다. Quality characteristics of mash of tskiu prepared by rice nuruks and wheat nuruk were studies during fermentation. Traditional nuruk were made from rice and wheat, and contained various wild type microorganism. Aspergillus oryzee, and Rhizopus japonicus were inoculated on rice as improved method (improved nuruk), Lactic acid, succinic acid and citric acid were found in all treatments during fermentation. Total amount of organic acid was 147.40~820.89mg% in the treatment with wheat tiuruk and 150.80~278.40mg% for traditional rice nuruk. As a major organic acid in tskju, lactic acid was 19.20~649.85mg% and showed maximum content after 8 days of fermentation. The contents of free sugar were 71.24~778.68 mg and the highest content was found in the treatment with traditional rice nuruk. Glucose (63.50~748.88mg%) was shown as a major free sugar. Free amino acid content (203.5~430.3mg%) in nuruk using rice as a mateial was relatively higher than that of the others. Alanine, glutamic acid, arginine, proline, tryptophan, and leucine were found higher amount in nuruk than the other amino acids. Total contents of n-propyl alcohol, iso-butyl alcohol, iso-amyl alcohol were in the range of 0~704ppm and iso-amyl alcohol content was higher than the others. Higher content of this fusel oil was found in the treatment with traditional wheat nuruk and rice nuruk.

치면열구전색제의 조건에 따른 법랑질 결합강도에 관한 연구

이용근,이흥수,이성재,방기숙,최정민,류승호,강민석 대한치과기재학회 1997 대한치과재료학회지 Vol.24 No.1

In this study, the shear bond strengths and accompanying elastic modulus ratio, displacement at bond failure and work up to fracture of pit and fissure sealants to toothe enamel were analyzed by the following variables, those were acid etching, moisture content of the surface of enamel, dentin bonding agent(species and method), thermocycling, saliva contamination. One kind of chemically cured resin based pit and fissure sealant, two kinds of light cured resin based pit and fissure sealants and one kind of glass ionomer based pit and fissure sealant, and two kinds of dentin bonding agents were studied. The buccal surface of extracted premolars were ground flat with # 600 silicone carbide papers, and the ground surface was treated depending on the experimental conditions. After each treatment, each pit and fissure sealant was filled into plastic tube of 3mm diameter, which were laid on the surface of ground enamel surface, and were cured. Sealant bonded teeth specimens were immersed in 37℃ distilled water form 24 hours. The shear bond strength of sealant to enamel surface was measured with Universal testing machine with the cross head speed of 1mm/min. From the obtained load-deflection curves, modulus ratio, bond strength, displacement at bond failure and work up to fracture were analyzed. From this experiment, the following results were obtained : 1. Comparing the results of standard condition(i. e. acid etching, dry surface, no dentin bonding agent and 300 thermocyling), the elastic modulus ratio of chemically cured resinbased pit and fissure sealant was significantly higher than those of other materials(P<0.05), and the bond strength, displacement at bond failure and work up to fracture of glass ionomer based pit and fissure sealant were significantly lower than those of other materials(P<0.05). 2. The results of ANOVA with the variables of type of material, acid etching, moisture condition of the enamel surface, dentin bonding agents were as follows ; 1) variables showed significant main effect on the shear bond strength of pit and fissure sealant to enamel(P<0.01), 2) type of material, acid etching and moisture condition of enamel influenced the bond strength significantly(P<0.01), 3) type and application methods of dentin bonding agents influenced on the bond strength significantly(P<0.05). 3. There were statistically significant correlation between the work up to fracture and the bond strength, and between the work up to fracture and the displacement at bond failure(P<0.01), and in these cases the correlation coefficient was 0.87.

쌀누룩으로 담금한 탁주 술덧의 발효 중 이화학적 품질특성 변화

이홍숙,이택수,노봉수 서울여자대학교 자연과학연구소 2004 자연과학연구논문집 Vol.16 No.-

쌀을 이용하여 만든 재래식의 쌀누룩, Aspergillus oryzae, Rhizopus japonicus의 개량식 쌀누룩 및 재래식 밀누룩으로 탁주를 담금하여 발효과정 중의 품질을 비교한 결과는 다음과 같다 에탄올은 발효 10-14일에 10.6-14.8%로 최대함량을 보였고 발효과정 중 쌀누룩구는 밀누룩구보다 에탄올 함량이 높았다. 쌀누룩구 중에는 발효 14일에 Aspergillus oryzae의 쌀누룩구가 14.8%로 가장 높았다. pH는 담금일에 4.80-5.33이였으나 발효 2일후 3.71-3.88로 크게 저하되었고 발효중 시험구간의 pH차이는 없는 편이였다. 총산은 발효 12일에 0.57-1.06% 최대함량을 보였고 밀누룩구는 쌀누룩구보다 총산 함량이 현저히 높았으나 쌀누룩구간의 차이는 없었다. 총당은 담금일에 15.58-18.50% 로 최대치를 보였으나 발효 14일에 4.59-6.20%로 감소하였고 담금일에는 재래식의 쌀누룩구가, 발효 14일에는 재래식 밀누룩구에서 각각 높은 편이였다. 환원당함량은 담금일과 2일에 1.72-6.96%로 가장 높았고 이후 감소하여 발효 10일 후는 1.8 % 미만으로 나타났다. 환원당 함량이 높게 나타난 발효 2일에 Rhizopus japonicus 누룩구에서 환원당함량이 높았고 재래식 밀누룩구에서 낮은편이었으나 발효 10일후는 시험구간의 차이가 없었다. 아미노태 질소함량은 밀누룩구가 쌀누룩구 보다 현저히 높았다. 탁주의 색은 육안관찰결과 쌀누룩구는 백색, 밀누룩구는 흑갈색이 가미된 백색으로 구별되었고 chroma meter의 측정에의 한 밝기는 쌀누룩구가 밀누룩구보다 강하였고 Aspergillus oryzae 쌀누룩구는 시험구중 명도가 가장 높았다. 적색도는 재래식 밀누룩구가, 황색도는 Rhizopus japonicus 누룩구에서 다소 높게 나타났다. Quality characteristics of mash of tskju prepared by rice nuruk and wheat nuruk were studied during fermentation. Those tiuruks were cultured with wild microorganism on wheat, and rice as a traditional method (traditional nuruk) Aspergillus otyzse, and Rhizopus jsponicus were cultured on rice nuruk as improved method (improved nutuk). Ethanol content reached maximum of 10.6-14.8% after 10-14 days of fermentation. The ethanol content (14.8%) of mash with rice nuruk was higher than that of mash with wheat nuruk. Tekju with rice tiuruk cultured using Aspergillus oryzse showed the highest ethanol content. No difference in pH was observed among the treatments. Total amount of organic acids were highest (0.57-1.06%) after 12 days of fermentation and that of mash with wheat nutuk was predominantly higher than that of mash with rice nuruk. The total sugar contents ranged from 15.58 to 18. 50% on the starting day of fermentation, and decreased to 4.59-6.20% after 14 days of fermentation. The total amount of reducing sugar ranged from 1.72 to 6.69% on the initial stage of fermentation, and decreased less than 1.8% after 10 days of fermentation. Reducing sugar content in tskju with nuruk using Rhizopus japonicus was high while low content in tskju with traditional wheat nutuk at the initial stage of fermentation. Amino nitrogen of tskju with wheat nuruk was much higher than that of tekju with rice nuruk. Lightness of tskju with rice tiuruk using Aspergillus oryzse, showed higher value than the other treatments. Redness for tskju with wheat nuruk and yellowness for takju with nuruk using Rhizopus japonicus showed higher valuc.

FDTD법을 이용한 원통형 유전체 공진 안테나 해석

이권익,김흥수 濟州大學校 情報通信硏究所 1999 情報通信硏究所論文集 Vol.2 No.-

In this paper. finite-difference time-domain(FDTD) method is employed to analyze a probe-fed cylindrical dielectric resonator antenna. The effect of various parameters on the characteristics of the DR antenna are studied. The impedance matching of the antenna can be accomplished by adjusting the position b and the length l of the coaxial probe. As ε_(r) is increased. the resonanat frequency decreases and the value of the input impedance increases.