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전덕인,윤보현,정한용,하규섭,신영철,박원명 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.5
Objectives : This study aims to test the validity of the Korean version of Mood Disorder Questionnaire (K-MDQ), a Screening instrument for bipolar disorder. Methods : A total of 238 subjects (126 DSM-IV bipolar outpatients and 112 controls without psychiatric history) completed the K-MDQ. Results : The Cronbach's alpha, used to measure the internal consistency of the scale, was high (0.88). Principal component analysis with varimax rotation revealed three factors, which explained 59.5% of the variance. Individual item correlations with the total score were all statistically significant (p<0.001). The mean total score of the K-MDQ was 8.48 in bipolar disorder and 4.51 in non-clinical participants. A total K-MDQ score of 7 or more excluding further two questions was chosen as the optimal cutoff, as it provided good sensitivity (0.75) and specificity (0.69). Conclusion : The results of this study showed adequate validity of the K-MDQ, suggesting that this instrument is useful for screening of bipolar disorder.
논문 : 청원-충주지역 수막재배용 지하수 사용량 및 배출량 분석
문상호 ( Sang Ho Moon ),하규철 ( Kyoo Chul Ha ),김용철 ( Yong Cheol Kim ),윤필선 ( Pil Sun Yoon ) 대한지질공학회 2012 지질공학 Vol.22 No.4
국내 수막재배지는 시설 증대로 인한 지하수 취수량 감소의 어려움을 겪고 있다. 이 연구는 이들 지역 중 청원-충주지역을 대상으로 지하수 이용량 및 배출량을 측정하고, 이를 토대로 국내 수막재배지에서의 지하수 이용량을 추정하였다. 대표 관정들의 모터사양과 1일 지하수 토출 능력과의 관계, 1일 최저 기온0℃ 이하의 기록 일수, 최저 기온 변화에 따른 모터 가동 상황 등을 토대로 하여, 청원지역에서 2011~2012년 겨울철 수막재배에 이용된 지하수 이용량을 추정하면 1ha 당 53,138m3이 된다. 이에 의한 면적 대비 국내 수막재배지 (10,746ha)의 지하수 이용 총량은 약 5.7억 m3이며, 이는 국내 농업용수 지하수 이용량 16.9억 m3 33.7%에 해당된다. 2012년 2월 9일부터 22일까지 면적 4ha의 청원지역 배수로에서 측정한 1일 지하수 배출량은 2,079~2,628 m3범위(평균 2,341 m3)로서, 수막재배 면적 1ha 당 1일 평균 지하수 배출량이 585m3인 것으로 나타났다. 수막재배 일수 94일을 적용하면, 청원지역에서 2011년~2012년 겨울철에 수막재배에 이용된 지하수 이용량은 54,990m3/ha이다. 이에 의한 면적 대비 국내 수막재배지의 지하수 이용 총량은 약 5.9억 m3이며, 이는 전체 농업용수 지하수 이용량의 약 34.9%에 해당된다. 충주지역에서는 수막재배지 1ha 당 1일 지하수 배출량이 805 m3 미만일 것으로 추정되었다. 이 지역에서의 2011년~2012년 겨울철 수막재배 일수 108일을 적용하면, 면적 대비 국내 수막재배지의 지하수 이용량은 전체 농업용수 지하수 이용량의 55% 미만일 것으로 추정된다. Korean agricultural areas that employ water curtain cultivation (WCC) have recently suffered extensive groundwater short-ages due to an increase in the number of facilities. The primary focus of this study is to measure the daily groundwater use and discharge rates in the Cheongweon and Chungju pilot areas, while the second focus is to estimate the total amount of groundwater used in WCC areas nationwide in Korea. Taking inwo consideration several factors, including motor type, out-flow abilities of wells, records of daily minimum temperatures below 0℃, and the number of running wells accrding to weather variations, we estimated that 53,138m3/ha of groundwater had been used in the 4-hectare Cheongweon pilt area during the winter period of late 2011 through early 2012. On a prorated areal basis, we can calculate that the total ground-water used nationwide was 0.57 billion m3 in WCC areas of 10,746m2. This value is equivalent to 33.7% of the total agri-cultural groundwater use (1.69 billion m3) in Korea. During 9-22 February 2012, the daily water discharge rate in the 4-ha Cheongweon pilot area raged from 2,079 to 2,628m3, averaging 2,341m3. Combining this value with meteorological records for 94 days with a daily minimum temperature below 0℃ results in an estimated groundwater volume of 54,990m3/ha for the pilot area during the 2011-2012 winter period. The total amount of groundwater used nationwide in WCC areas would then be 0.59 billion m3, equivalent to 34.9% of the total agricultural groundwater use in Korea. In the Chungju area, the groundwater discharge rate was estimated to be less than 805m3/ha. This value, combined with weather data for 108 days with a daily minimum temperature below 0℃ in this area, can be applied to infer that the total groundwater vol-ume used in WCC areas nationwide is no more than 55% of the total agricultural groundwater use in Korea.
입원중인 정신분열증 환자의 지연성 운동장애 유병율에 관한 연구
하규섭,이인표,김철응,이주호,공재연,이강희 대한신경정신의학회 1994 신경정신의학 Vol.33 No.3
The point prevalence of TD as assessed by Abnormal Involuntary Movement Scale(AIMS) was determined for chronic wards with 361 schizophrenic patients(194 male, 167 female)(mean age 37.3±10.4) at the time of the study. The results were as follows : 1) When TD was defined as those with a rating 3 or higher for any one or more than one of seven body items, the prevalence rate was 17.0% in 194male schizophrenics, 22.8% in female and mean 19.7%. 2) Among the risk factors, age was statistically significant relationship with the occurrence of TD and there was no significant relationship between the occurrence of TD and there was no significant relationship between the occurrence of TD and sex, the use of antiparkinsonian agent, history of electroconvulsive therapy and dosage of antipsychotics at the examination. 3) TD of the orofacial region was positively associated with age and history of ECT, while TD of non-orofacial(trunk and extremities) regions were not related. Our findings suggest that prevalence of TD in the schizophrenics was positively associated with age, and TD of the orofacial and non-orofacial regions may be distinct clinical syndromes, each having a different set of etiological determinants.
혈액투석 중인 만성 신부전 환자에서 G 형 간염 바이러스의 감염률 및 임상적 의의
최규완,백승운,김정룡,이준혁,고광철,이종철,이윤하,김윤구,오하영,이효석 대한소화기학회 1999 대한소화기학회지 Vol.33 No.1
Background/Aims: We aimed to elucidate the prevalence and risk factors of HGV infection in patients with chronic renal failure undergoing hemodialysis, and to define the potential etiologic-role of HGV in the development of chronic liver disease. Methods: One-hundred and seventy-eigh patients with chronic renal failure undergoing hemodialysis were included. After extraction of RNA from serum, reverse transcription polymerase chain reaction was performed using the primers from the NS5a region. The PCR products were analyzed by liquid hybridization. Results: The prevalence was 9.0% (16/178). The prevalence rates were not statistically different according to the presence (8.5%) or abscence (10.8%) of past history of blood transfusion, patient's age or maintenance duration of hemodialysis (p$gt;0.05). Anti-HBc-positive patients (12.4%, 16/129) showed significantly higher prevalence rate (p=0.01) of HGV infection than anti-HBc-negative patients (0%, 0/49). Twelve of the 14 HGV positive patients without co-infection showed persistently normal ALT level during a year of follow-up. Conclusions: The prevalence of HGV in patients with chronic renal failure undergoing hemodialysis is significantly higher than that of volunteer blood donors. HGV may share the route of transmission with adulthood HBV infection. The etiologic-role of HGV in the development of chronic liver disease may be considerably poor. (Kor J Gastroenterol 1999;33:78 - 89)
원저 : 폐암 환자에서 촉진되지 않는 경부 림프절에 대한 초음파 유도 하 세침흡인 세포검사의 유용성
김희규 ( Hee Kyoo Kim ),하승인 ( Seung In Ha ),김유리 ( Yu Ri Kim ),박찬복 ( Chan Bog Park ),옥철호 ( Chul Ho Oak ),장태원 ( Tae Won Jang ),정만홍 ( Maan Hong Jung ),오경승 ( Kyung Seung Oh ),천봉권 ( Bong Kwon Chun ),이민기 ( Min 대한결핵 및 호흡기학회 2004 Tuberculosis and Respiratory Diseases Vol.56 No.5
급성 골수성 백혈병에서 고용량 Cytarabine 을 이용한 공고요법
김도하(Do Ha Kim),이규형(Kyoo Hyung Lee),조재근(Jae Kun Cho),김선희(Seon Hee Kim),이제환(Je Hwan Lee),김성배(Sung Bae Kim),김상위(Sang We Kim),서철원(Chul Won Suh),이정신(Jung Shin Lee),김우건(Woo Kun Kim),김상희(Sang Hee Kim) 대한내과학회 1996 대한내과학회지 Vol.51 No.4
N/A Objectives: This study was designed to evaluate the therapeutic efficacy of postremission therapy utilizing high-dose cytarabine in patients with newly diagnosed acute myelogenous leukemia and to assess the toxicities of the therapy. Acute promyelocytic leukemia (FAB M3) is excluded because it has very unique clinicopathologic characteristics. Methods: Those patients who achieved complete remission had first consolidation therapy with conventional dose cytarabine and daunorubicin but second and third consolidation was done with high-dose cytarabine (cytarabine 1gm/㎡ i.v. over 1 hour every 12 hours daily for 5 days) and daunorubicin. Overall survival and disease free survival were compared with previous conventional dose cytarabine and daunorubicin postremission therapy. Results: 1) Complete remission occurred in 62% (28 of 45 patients) and control group 48% (14 of 29 patients) (p=0.15). 2) The median survival of all 45 patients was not different significantly compared with control group (10 months vs 7 months, p=0.08). 3) The median disease free survival of 21 complete responders receiving at least one course of consolidation was 10 months and there was no significant difference compared with control group 7 months (p=0.47). 4) The toxicity including treatment-related motility, neutropenia duration was similar in both groups. Conclusion: Although our high-dose cytarabine consolidation therapy regimen appeared to have acceptable toxicity, its results did not show the superiority to previous conventional dose cytarabine consolidation regimen.