FCT 5 : Fractional laser-assisted topical imiquimod 5% cream treatment for recalcitrant common warts in children

( Hyun Chang Ko ),( Jeong Min Kim ),( Hyun Ho Cho1 ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Conventional destructive modalities for warts like cryotherapy or laser ablation have some limitations that are excruciating pain during procedure, in especially pediatric patients. Imiquimod is a topical immune response modifier that was approved for treating genital and perianal warts. But, thick stratum corneum of common warts may act as a barrier against drug permeation via the skin. Objectives: To evaluate efficacy and safety of above treatment. Methods: Eleven pediatric patients (6 female and 5 male, mean age 12.5 years) were included in this study. The lesions were treated by fractional 2940 nm Er:YAG laser for achieving the penetration of stratum corneum with 1 or 2 weeks intervals. Then, imiquimod 5% cream was self-applied once daily for 5 days a week. Assessment of response and adverse effects was performed every 2 weeks until complete clearance or up to maximum of 48 weeks. Pain during procedure was checked by VAS (0-10). Results: 8 out of 11 (72.7%) patients experienced complete clearance of all warts lesions. Mean duration of total treatment was 29.7 (16-48) weeks. Mean number of fractional laser treatment was 17.5 (8-37) times. No significant adverse effect was observed. VAS score of the pain during fractional laser treatment was 2.4 (1-4), comparing with 6.2 (5-8) during cryotherapy. Conclusion: Fractional ErYAG laser-assisted topical 5% imiquimod cream is an effective and safe treatment option for recalcitrant common warts of the children do not tolerate pain well.

White luminescence of Ho3+/Tm3+/Yb3+-codoped CaWO4 synthesized via citrate complex route assisted by microwave irradiation

CHO, Hyun,HWANG, Seok Min,LEE, Jae Bin,KA, Dong Hyun,KIM, Tae Wan,LEE, Bo Seul,LEE, Ji Young,LEE, Jung-Il,RYU, Jeong Ho Elsevier 2014 Transactions of Nonferrous Metals Society of China Vol.24 No.suppl1

기종성 신우신염의 임상양상 및 사망위험인자

조수연,이호재,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Emphysematous pyelonephritis (EPN) is an acute gas forming necrotizing infection of the renal parenchyma with high mortality. Although its incidence is relatively low, it mostly occurs in patients wiith diabetes mellitus. The aim of the study is to identify the risk factors related to mortality and assess the outcome of managements according to the radiologic classification. Materials and Methods : The clinical records of 23 patients diagnosed with EPN were reviewed retrospectively. The cases were grouped into two types on the basis of computed tomography scan. Type 1 EPN was defined as renal necrosis and gas formation with total absence of fluid content. Type 2 EPN was defined as the presence of renal or perirenal fluid in association with bubbly or loculated gas pattern. The patients' symptoms, performed investigations, and treatments were analyzed. Results : All patients had diabetes mellitus. Escherichia coli (78.6%) was the most common pathoqen in urine and blood cultures. The factors showing statistically significant differences between survivors and non-survivors were age (P=0.013), the presence of obstructive uropathy (P= 0.008), and type 1 group (P=0.030). Multivariate logistic regression showed that factor significantly related to death was age (odds ratio=1.20, 95% confidence interval 1.01-1.38, P=0.037). Conservative treatment including antibiotics and percutaneous drainage was successful in type 2 group, Overall mortality was 26.1%; all expired patients were from type 1 group. The mortality of conservative treatment and nephrectomy in type 1 group was 83.3% and 20.0%, respectively. Conclusion : These results suggest that old age is a significant risk factor for mortality in patients with EPN. Nephrectomy should be considered as the main treatment option in patients with type 1 EPN.

면역억제제를 사용치 않은 동소성 간이식 실험견의 조직병리소견

조원현,최순옥,김인호,임태진,김성수,박준희,김우석,김현철,최규택,김진모,권건영 大韓移植學會 1994 Korean Journal of Transplantation Vol.8 No.1

흉배혈관의 근피 천공분지에 기초한 유리피판의 임상적 이용

조규성,김대영,안호범,이삼용,조백현 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

The latissimus dorsi muscle or musculocutaneous flap is one of the most useful flaps in reconstructive surgery. This flap has many advantages, such as its reliable anatomy, long pedicle with large caliber vessels, minimal functional deficit of the donor site, and low incidence of donor site complications. However, the bulkiness of the flap has been considered a disadvantage, so various modifications of technique have been devised. The cutaneous portion of the flap can be safely elevated based on the cutaneous perforating branch of the thoracodorsal vessel. From March 1997 to February 1998, 10 patients underwent reconstructive procedures with thoracodorsal perforator-based free flaps. The composition of the flaps varied in accordance with the nature of the defect. The variances in the flaps were as follows; 3 were cutaneous, 6 musculocutaneous, and 1 osteomusculocutaneous including the rib. All flaps survived with good contour. We concluded that this thin and reliable flap was useful for reconstruction of various defects, and that the composition of the flap, such as subcutaneous, muscle and bone, gave it considerable flexibility as needed.

프로축구 선수들의 포지션별 유산소성 파워능력과 슬관절 등속성 근 기능의 특성

조현철,김준호,강민철,김종규 龍仁大學校 體育科學硏究所 2004 體育科學硏究論叢 Vol.14 No.1

The purpose this study was to investigate the aerobic power and isokinetic muscular function of knee joint for korea the pro-soccer players in field position. Data were obtained from thirty one pro-soccer players. They didn't have any medical problem. They performed exercise stress test and isokinetic muscular function on treadmill and Isomed 2000. The assessment of cardiorespiratory and isokinetic muscular function were VO2max, Maximal heart, ATVO2, AT heart rate, Total Work, Average Work, Maximum Torque, Maximum Work and Flex/Ext. A two-way analysis of variance with repeated measures(two-way(2x4)RM ANOVA) was used to compare group and field position differences aerobic power and isokinetic muscular function. A Tukey post hoc test was used when significant mean differences were observed. Statistical significance was accepted as p<O.05. Aerobic power do not showed any significant difference among in field position. Hamstring muscle power was significantly higher in Forward and Middle field than Defense and Goal keeper. Muscular endurance was higher Defense and Goal keeper than Forward and Middle field. Based on the facts that we have discussed, aerobic and anaerobic power in field position do not showed any difference. However, isokinetic muscular function was significant difference in field position. Ratios of conventional and functional for isokinetic Hamsting: Quadriceps muscle strength in soccer player for prediction and decision injures, it is thought that more researches on it should be required.

RAPD分析法에 의한 참나무 優良種의 PCR反應 分析

趙顯瑞,李喆浩,李正煥 진주산업대학교 1999 산업과학기술연구소보 Vol.- No.6

RAPD를 이용한 참나무류의 band pattern은 primer의 종류에 따라 공시 수종별로 구분이 가능한 표식인자(marker)를 가지고 있었고, 상수리나무 (lane 1-11) band pattern에서는 고유 band를 보였다. Primer OPA-10, OPA-16에서 갈졸참나무 (lane 28)은 갈참나무(lane 22-25) 및 졸참나무 (lane 12-17)와 공유 band가 있었으마, 갈참나무와 유사한 band pattern을 보여 갈참나무와 유사한 경향을 보였다. 촐참나무 (lane 12∼17), 갈참나무 (lane23∼27)와 갈졸참나무(lane28) 집단 간에는 유사한 band pattern을 보여 갈졸참나무가 갈참나무에 근접한 교잡종으로 인식되었다. 군집분석결과 28개 집단은 7개 Grpup로 분류되었는데, 제1 집단은 상수리나무, 제 2 집단은 갈참나무, 제 3집단은 졸참나무 등으로 집단간 종의 구분이 가능하였다. In the Polymerase Chain Reaction (PCR) - Random Amplified Polymerase (RAPD) DNA analysis was performed on DNA samples obtained from leaf collected from wild Quercus spp. in Kyeongnam Province. PCR - DNA markers were used as a predictor of superior tree in future Quercus spp. breeding development. Eight primers were used for PCR and generated a total of 122 RAPD markers. According to the PCR products bands of Q. acutissima (lane 1-11), Q. serrata (lane 12-17), Q. uariabilis (lane 18-22), Q. aliena (lane 23-27) a n d Quercus x urticaefolia (lane28) were detected in all samples. Genetic relationships among the 28 individual samples were analyzed by the cluster analysis of 122 RAPD markers, which divides seven groups. According to the cluster analyses, First group are contains Q. acrtissima. Second group are Q. aliena, third group Q. serrata and so on. And close relationship between Quercus x urticaefolia and Q. aliena were ascertained by cluster analysis.

신뢰성방법에 기초한 강교량의 잔존피로 수명 및 피로 위험도 평가

조효남,임종권,최현호 漢陽大學校 工學技術硏究所 1999 工學技術論文集 Vol.8 No.1

본 논문은 잔존피로수명 및 피로파괴 신뢰성해석 절차의 확립을 위해 피로신뢰성방법에 대한 기존 국내외 관련 연구에 대한 심도 깊은 고찰을 수행하였고 실온적인 평가방법을 제시하였다. 따라서 본 연구에서는 Miner 누적손상법칙에 기초한 S-N 피로해석이론 중에서 주로 확률적 S-N 방법과 Ang-Munse's방법에 대한 최근 평가 기술을 집중 고찰하였으며, 이를 실제 성수대교의 붕괴원인 규명에 적용해 봄으로써 그 타당성을 검증하였다. 또한 이를 위해서 성수대교의 붕괴 원인으로 추정되고 있는 핀연결 수직재의 피로응력범위의 보다 정확한 추정을 위하여 shell요소를 사용한 엄밀 국부 FEM해석이 수행되었다. This paper presents practical evaluation methods of the fatigue life and fatigue failure probability for the assessment based on all the available results of various field and labolatory tests. Therefore, both the probabilistic S-N approach and the well known Ang-Munse's fatigue reliability method based on linear damage-accumulation hypothesis, commonly known as Miner's rule, are used and demonstrated in order to verify it's appropriateness. A local FEM analysis using fine meshes shell elements is carried out for the more precise estimation of stress range of the vertical pin-connected hanger whose fatigue fracture triggered the collapse of the bridge.

연쇄상구균을 실험감염시킨 넙치치어의 병리조직학적 관찰

조성환,류시윤,김현수,박배근,김덕환,손화영,윤원기,신창호 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

Pathological observations were examined after abdominal inoculation in 7∼8㎝ sized flounder (Paralichthys olivaceus) with 1X10^7 cfu/㎖ of Streptococcus faecalis. The infected flounder were clinically observed and weighed a fish body at 0, 5, 10, 15, 20, 25, 30 days post inoculation. In infected group, mortality were 70% and feed efficiency were 7.2%. In non-infected group, mortality were 10% and feed efficiency were 18.2%. Macroscopically, the significant lesions were characterized by protrusions and opacity of the eyes and ulcer of the caudal pecuncle. Histopathologically, the lesions were observed a degeneration. necrosis and inflammatory cells in muscle of the caudal peduncle and a degeneration and necrosis of the rod cells and detached retina from the black pigmented layer

참나무 幼齡化 접수에 의한 接木法 開發에 관한 연구

趙顯瑞,李喆浩,秋甲喆 진주산업대학교 1999 論文集 Vol.38 No.-

To obtain effective grafting propagation method, grafted rejuvenation shoots at seedlings of Q. acutissima, Q. aliena and Q. dentata, respectively. The result investigated at April and October are as follows: The survival ratio of Q. acutissima, Q. aliena and Q. dentata in grafting at April were 75%, 58% and 51%, and at October were 87%, 76% and 71%, respectively. The height of Q. acutissima which grafted cuttings growth highest, was 120㎝, Q. aliena and Q. dentata were 80㎝ and 71㎝. Grafting method by rooted cuttings at seedlings at Q. acutissima is most effective.