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      • KCI등재

        24주간 추적하는 임상 연구에서 한국인 남자 알코올 의존 환자의 비재발률

        강철중,김성곤,남궁기,조동환,이병욱,최인근,최용성,박성봉,제영묘,김현경,김성연 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.1

        Objetives : In order to provide useful data tbr the further clinical studies with Korean alcohol-dependent patients, enrollment and non-relapse rates were investigated while alcohol-dependent patients wcre followed up for 24 weeks. Methods : The subjects of this study were alcohol-dependent male patients who, for the first time, visited a hospital among 3 groups of hospitals, University Hospital, General Hospital or Mental Hospital, or those who needed to be followed up after discharge from those hospitals. After assigning 12 subjects to each hospital, we investigated enrollment and non-relapse rates while cognitive-behavioral therapy and pharmacotherapy were provided. Results : 1) Forty-eight patients were enrolled and the rate of enrollment was 36.4%. The enrollment rate in the University Hospital group was 52.1%, in the General Hospital group 50.0%. and in the Mental Hospital group 10.4%. 2) In 48 patients, non-relapse rate was 27.1% at 12 week and 18.8% at 24 weeks after starting follow-up. It was 24.4% and 20.0% at 12 and 24 weeks, repectively, in the University Hospital group while the General Hospital group showed 33.3% and 16.7%, respectively, and the Mental Hospital Group showed 20.0% at both 12 and 24 weeks. Conclusion : These results provide important data for further clinical studies of Korean alcohol-dependent patients.

      • 反撥硬度法에 의한 高溫受熱콘크리트의 强度推定에 關한 實驗的 硏究

        姜丙熙,張承宰 동아대학교 공과대학 부설 한국자원개발연구소 1988 硏究報告 Vol.12 No.2

        The results both non-destructive test and compressive strength test, by rebound hammer testing method, to highly heated concrete are the inferential formula of compressive strength, as follows : (1) Air circuit leave for 24 hours after heating Fc= 7.53R-70.69 (2) Air circuit leave for one month after heating Fc= 7.62R-78.07

      • KCI등재

        화학제재를 이용한 우식상아질 제거 효과 및 레진과의 결합강도에 관한 연구

        강덕일,이병채,설재헌 조선대학교 구강생물학연구소 2003 口腔生物學硏究 Vol.27 No.1

        The aim of this study was to evaluate the effect of chemo-mechanical caries removal system(CarisolvTM, Medi Team. Sweden) for resin adhesion to carious primary and Permanent dentin compared with conventional drilling method. The buccal surface of 92 Primary molars and 92 permanet molars were used. Exposed dentins were occurred artificial caries. 32 tooth of primary molars and 32 tooth of permanet molars were prepared to observe treated dentin surface with CarisolvTM and conventional drilling method by SEM. Other tooth were prepared to measure resin-dentin shear bonding strength according to caries removal methods and dentin adhesive system. Two adhesive systems and a composite resin were used: single bonding agent(Scotchbond Multi-Purpose Plus, 3M) and self-etching bonding system(Prompt L-Pop, 3M ESPE), and a composite resin(Z-250, 3M) The results were as follows : 1. The effect of CarisolvTM on primary dentin was stronger than that to permanent dentin, and dentin surface became rougher with treated CarisolvTM than drilling method. 2. Acid-etched dentin surfaces were showed smoothing without smear layer. 3. In specimen applied single bonding system hybrid layer and adhesive layer were 3-4㎛ and 10-15㎛ in thickness, whereas self-etching bonding system hybrid layer were 1-2㎛ 4. The shear bonding strength of group applied single bonding agent was higher than that applied self-etching priming system(P<0.05). 5. The shear bonding strength of group applied CarisolvTM and self-etching priming system were slightly higher than that applied conventional drilling method and self-etching priming system(P>0.05).

      • KCI등재후보

        상아질에 적용된 재 습윤제가 미세인장 결합강도에 미치는 영향

        강희영,조영곤,김종욱,박병철,유상훈,진철희,최희영,기영재 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.2

        This study investigated that the effect of rewetting agent on dentinal microtensile bond strength (μTBS). Human molars were sectioned to expose the superficial dentin surfaces. Samples were divided into two groups according to type of adhesives-Single Bond (S) and One-Step (0)], and again subdivided into five groups by different dentin surface treatment-dry for 15s (D) , blot dry (BD) or dry for 15s, and rewet with different rewetting agents[distil1ed water (DW), Gluma Desensitizer (GD) and Aqua-Prep (AP)]for 30s. After application of adhesive, composite resin was built up on the bonding surface. Each tooth was sectioned to obtain stick with 1mm^(2) cross sectional area and the μTBS was determined by EZ test. In the S group, the mean μTBS of GD, AP and BD group was significantly higher than that of DW and D group (p < 0.05). In the 0 group, the mean μTBS of AP, GD, BD and DW group was significantly higher than that of D group (p < 0.05). The data suggested that Gluma Desensitizer and Aqua-Prep could be successfully used as rewetting agents, and Distilled water could be acceptable in aceton based adhesive system only.

      • 정신분열병 환자에서 Olanzapine이 인지기능에 미치는 영향

        강병조,김양태,김문두,이승재,박영우 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.1

        Objects : The purpose of this study was to test the effects of olanzapine on cognitive functions in schizophrenic patients. Methods : The subjects were 16 haloperidol-medicated schizophrenic patients and 15 risperidone-medicated schizophrenic patients, who participated in an eight-week crossover study from haloperidol and risperidone to olanzapine. Results : The patients in the group of crossover from haloperidol to olanzapine showed significant improvement in Parkinson scale of ESRS and other cognitive functions except for verbal fluency. Negative scale of PANSS and cognitive functions such as verbal memory, verbal fluency, visual memory and executive function were significantly improved in patients In the group of crossover from risperidone to olanzapine. Conclusions : These data suggest that olanzapine has some superior cognitive benefits relative to haloperidol and risperidone, but a larger sample replication study is necessary.

      • 도시지역 한방의료이용자의 질병양상 조사연구

        강영우,조태현,김병하,남철현,조남춘,안창수,이재홍 慶山大學校 保健福祉硏究所 1997 保健福祉硏究 Vol.1 No.-

        To provide the basic data for improving of curative measures in oriental medicine and for developing of health education and preventive program after understanding of classification of diseases in oriental medicine users, questionnaire interview was carried out with city dwellers, over 20 years old, selected randomly in big cities from 2nd Oct. to 11th Nov. 1995. The results were summarried as follows: 1. In the general characteristics of subjects, the highest portion of each part was 61.2% of female, 25.5% of thirties, 28.5% of high school graduate, 63.3% of middle class and 11.8% of lower class in economic status. 31.9% was housewife, 73.5% was merried and 55.1%, 38.1% came from big or small cities each. 2. By 21 classification of diseases, 19.7% was blood disorders, 17.6% was pregnancy & delivery complications and 15.2% was endorine & nutritional disorders. 3. As for age 22.6% of endocrine & nutritional disorders in twenties, 20.8%, 28.1%, 27.8% of blood & defence mechanism disorders in thirties, forties, sixties each and 24.9% of pregnancy & delivery complications in fifties were the higher than the other groups. 4. By educational level, 47.8%, 30.5% of blood & defence mechanism disorders in uneducated and middle school graduate were the higher than the other groups. 5. As for occupation, 20.8%, 32.9% of blood & defence mechanism disorders in housewives and sales each, were the higher than the other groups. 6. By economic status, 20.2% of blood & defence mechanism disorders in middle and high class, were the higher than the other groups. 7. By marital status, 21.3% of endocrine & nutritional disorders in singles, 22.0%, 25.7% of blood disorders in having partners, were the higher than the other groups. 8. As for living areas, 18.2% of pregnancy & delivery complications in big city dwellers, 21.3% of endocrine & nutritional disorders in town dwellers were the higher than the other groups. The distribution of diseases in oriental medicine users wes very different by chracteristics according the results. So It's important and essential project to improve curative technics and to develop.

      • Lepromin 反應의 再檢討

        姜秉祚,金在植,金重明 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.1

        癩腫樣癩(L型) 532例, 非癩腫樣癩(nL型) 177例 都合 709例의 癩患者에 Mitsuda (M)抗原과 Dharmendra (D)抗原에 依한 皮膚反應을 實施하여 그 成績을 다음과 같이 要約할 수 있었다. 1. 早期反應에서는 理用의 判定規準으로 病型判定이 可能하다. 2. M抗原에 依한 晩期反應에서는 理用判定規準에 依하면 L型에서 陽性率이 너무 높았다. 3. M抗原에 依한 晩期反應에 있어서 陽性의 判定規準은 6~7mm 以上이 適當하였다. 4. M反應과 D反應의 48時間値는 매우 有意的 相關性이 있었고, L反應의 48時間値와 14日値도 亦是 有意 的인 相關性이 있었다. In the study of the lepromin reaction with 709 Leprosy patients consisting of 532 cases of lepromatous type and 177 cases of nonlepromatous type, the author has attempted a reevaluation of the lepromin reaction because of the likely disagreement of the present interpretation in the aspects of the determination of the type of leprosy. It was found that the lepromin reaction seemed to be reliable for the determination of the type of leprosy by the early reaction but was unable to determine by the delayed reaction because of the high positivity in the lepromatous leprosy with the Mistuda antigen. Hence in the delayed reaction it is thought to be necessary to increase the range of the diameter of the skin reaction to 6~7㎜. There were apparent correlations between the Mistuda and Dharmendra reaction in the early reaction and also between the early and delayed reactions with the Mistuda antigen.

      • 악성 갑상선 우연종의 임상상 및 초음파 소견의 진단적 가치

        강한욱,김광원,이병완,강보현,김형훈,김범진,정재훈,민용기,이명식,이문규 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

        연구배경: 최근 갑상선 초음파 검사의 빈번한 시행으로 갑상선 우연종의 발견이 증가하고 있다. 이러한 갑상선 우연종은 임상적으로 어떻게 접근하고 치료를 해야 하는지 적지 않은 문제가 되고 있다. 본 연구에서는 직경 1.5㎝ 이하의 갑상선 우연종의 유병률, 입상적 특징 및 초음파 특성, 그리고 가장 효율적인 진단적 접근에 대해 알아 봤다. 방법: 1999년 1월부터 2000년 12월까지 삼성서울병원 내과 및 일반외과로 갑상선 결절을 주소로 내원한 1457명을 대상으로 후향적 연구를 시행하였다. 우연히 발견된 직경 1.5㎝ 이하의 갑상선 결절을 가지는 환자들에서 갑상선 결절의 촉지 유무, 갑상선 기능검사, 항갑상선 항체, 갑상선 초음파 및 미세침 흡인세포검사, 99m^Tc 갑상선 스켄, 수술 조직검사 및 병기를 검토하였다. 결과: 분석한 갑상선 결절 1475예 중 갑상선 우연종의 유병률은 13.4%(198예)였다. 갑상선 우연종에서 악성률은 28.8%(57예)으로 나왔다. 양성 및 악성 갑상선 우연종에서 나이, 성별, 갑상선 기능검사, 결절 크기에는 의미 있는 차이는 없었다. 갑상선 스켄은 갑상선 우연종의 감별에 적합하지 않았다. 갑상선 결절의 초음파 지표 점수만이 양성 및 악석 갑상선 우연종의 감별에서 초음파 지표 점수의 민감도는 88.9%, 특이도는 74.4%, 양성 예측률은 92.4%로 나왔고 진단적 정환도는 85.5%였다. 갑상선암으로 수술을 받은 50명중 stage 1은 34명, stage 2는 6명, stage 3은 10명으로 대부분의 악성 갑상선 우연종은 낮은 TNM 병기로 나타났으나, 상당수에서는 국소 침범의 소견을 보였다. TNM 병기의 3기 환자 전부는 45세 이상이였고, 주로 갑상선암의 피막 침범에 의한 것이었다. 임파절 전이는 6명의 환자에서 나왔다. 결론: 악성 갑상선 우연종은 비교적 흔히 접할 수 있는 질환이며 양성 우연종과는 임상적으로 구별이 안 된다. 악성 갑상선 우연종은 발견 당시 대부분 낮은 병기이나, 갑상선의 피막 침범 및 임파절 전이가 상당수에서 발견되었다. 갑상선 우연종의 초음파 소견은 향후의 진단 방향을 제시하는 중요한 길잡이가 될 수 있다. 초음파 지표 점수 2점 이상의 갑상선 우연종에서만 초음파 유도 미세침 흡입검사를 권장한다. Background: High-resolution ultrasonography has made the detection of asymptomatic small thyroid possible. Recent increases in the detection of incidentalomas have created a clinical dilemma on how to properly manage such incidental nodules. We investigated the prevalence, clinical and ultrasonographic characteristics, and optimal diagnostic approach toward incidentally detected benign and malignant thyroid nodules of less than 1.5㎝ in size. Methods: A retrospective review was undertaken on the 1,475 patients who had visited Samsung Medical Center, Seoul Korea between January 1999 and December 2000. The review consisted of a physical examination of the thyroid gland, thyroid function test, antithyroid antibodies, thyroid ultrasonography, fine-needle aspiration biopsy, pathology and TNA staging of the incidentally detected thyroid nodules of less than 1.5㎝ in size. Results: The prevalence of thyroid incidentalomas was 13.4% and the malignancy rate within them was 28.8%. There were no significant differences in age, sex, thyroid function test and size between the benign and malignant incidentalomas. Ultrasonographic characteristics showed meaningful diagnostic value for the detection of malignancy in incidentalomas. Most malignant incidentalomas were of a low stage. Conclusion: Occult thyroid cancers are fairly common finding. There are no clinical difference between benign and malignant thyroid nodules less than 1.5㎝; however, ultrasonographic findings can be used to decision of optimal management strategies (J Kor Soc Endocrinol 17:649∼656, 2002).

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