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최효정,남순현,김현정,Choi, Hyojung,Nam, Soonhyeun,Kim, Hyunjung 대한소아치과학회 2018 大韓小兒齒科學會誌 Vol.45 No.3
이번 연구에서는 상악 중절치의 편측성 맹출 장애의 원인을 조사하고 매복된 치아들의 매복깊이, 매복각도, 치근발육 상태를 치과용 Cone-beam CT로 분석하여 치료방향을 예측하는데 도움이 되고자 하였다. 총 134명의 환자 중 상악 중절치의 편측성 맹출 장애로 진단된 평균연령은 7.9세였으며, 남자가 여자보다 2.1배 더 높은 빈도를 나타냈다. 맹출 장애의 주원인은 물리적 장애물로 과잉치와 치아종이 대부분을 차지하였다. 편측성 맹출 장애를 보였던 치아 중 물리적 장애물을 제거한 후, 78증례는 자발적으로 맹출하였으며 56증례는 비자발적으로 맹출하였다. 또한 편측성 매복 상악 중절치의 자발적 혹은 비자발적 맹출은 매복깊이, 매복각도, 치근발육 정도와 연관성이 있었다. 정상적으로 맹출한 치아의 매복 각도는 $50^{\circ}-90^{\circ}$ 사이였으며, 매복 상악 중절치의 자발적 맹출 빈도도 이 범위에서 가장 높았다. 또한 자발적 맹출에 걸린 시간은 매복각도와 치근 발육보다 매복깊이와 높은 상관관계를 보였다. 비자발적 맹출을 보였던 치아들 중 대부분은 교정적 견인에 의해 구강내로 맹출 되었고, 그 기간은 약 12개월 정도 걸렸으며, 교정적 견인기간은 매복깊이, 매복각도, 치근발육 정도와 통계적인 유의성을 나타내지 않았다. 이번 연구의 결과들은 편측성 상악 중절치 맹출 장애의 원인과 치료에 대한 정보를 제공할 수 있었으며, 치료 결과를 제공함으로써 향후 치료계획을 세우는데 도움이 될 수 있으리라 생각된다. The purpose of this study was to investigate the cause of eruption disturbance in the maxillary central incisor and establish the effective treatment plan by analyzing the vertical distance, angulation of long axis and root development of the tooth with eruption disturbance using the cone-beam CT. The average age of 134 patients diagnosed with unilaterally impacted maxillary central incisor was 7.9 years old and the male was 2.1 times higher than the female. The most common cause of eruption disorder was physical obstruction, especially mesiodens and odontoma. Of the teeth with unilateral eruption disorder, 78 cases erupted spontaneously and 56 cases erupted non-spontaneously after removal of physical obstruction. The possibility of spontaneous or non-spontaneous eruption in the unilaterally impacted maxillary central incisor depended on several factors, such as vertical distance, angulation of long axis and root development of unerupted tooth. The spontaneous eruption of the impacted maxillary cental incisor was most frequent at the angulation of long axis of 50 to 90 degrees, which is similar to the angulation of long axis of the normally erupted maxillary central incisor. In addition, the spontaneous eruption period of impacted maxillary central incisor was more influenced by the vertical distance than the angulation of long axis and the root development. Most of the teeth that showed non-spontaneous eruption had orthodontic traction, and these teeth were usually erupted within about 12 months. The period treated with orthodontic traction was no statistical significance with the vertical distance, the angulation of long axis, and the root development. This study will provide information on the cause of unilaterally impacted maxillary cental incisor and help to establish the future treatment plan.
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ELISPOT assay을 이용한 결핵균 특이 항원 검출-(T-SPOT.TB)
최효정,원혜지,송혜림,심한나,박윤정,김시내,박인혜,연지영,육지혜,지연희,우혜민,이소윤,김지영,김지원,곽지은,전창은,김은중(지도교수) 대한임상병리사협회 2010 조직세포검사학회 발표자료집 Vol.2010 No.-
배경: 결핵은 결핵균(Mycobacterium tuberculosis)의 감염에 의해서 발생하므로 결핵의 확진은 배양검사 등으로 환자의 검체에서 결핵균을 증명해야 한다. 전통적으로 투베르쿨린검사가 잠복 결핵의 유일한 진단법이었으나 비결핵항산균 감염이나 BCG 접종에 의한 교차반응이 있으므로 유용성이 떨어지며, 감염, 영양결핍, 림프계를 침범하는 질환에서는 위음성을 초래할 수 있다. T-SPOT검사는 잠복 결핵의 진단검사로 활동성 결핵의 진단에도 유용한 것으로 보고되고 있다.이에 저자들은 T-SPOT 검사 방법 및 원리를 알아보고자 하였다. 방법: T-SPOT검사는 헤파린 채혈관에 혈액 8ml를 채취하여 비중액을 이용하여 단핵구를 분리하고 250,000 cell/100uL로 세포부유액을 준비하였다. 항-인터페론감마 항체가 결합되어 있는 microplate의 4개의 well에 해당시약을 넣고 분리된 세포를 250,000개씩 넣은 후 37도에서 16~20시간 배양하였다. 다음날 well을 세척하고, conjugate 시약과 기질을 넣어 spot을 발현시켰다. 결과: 전체 152건중 양성은 55건(36.2%), 음성 90건(59.2%), 미정확 7건(4.6%) 로 나타났다. 고찰: T-SPOT검사는 결핵 감염의 진단에 있어 민감도가 높아 결핵의 선별 검사나 보조 검사로 유용하게 사용될 것으로 기대된다.
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Growth and Fabrication Method of CdTe and Its Performance As a Radiation Detector
최효정,정만희,김한수,김영수,하장호,채종서 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.66 No.1
A CdTe crystal ingot doped with 2000 ppm of Cl was grown by using the low-pressure Bridgman(LPB) method at the Korea Atomic Energy Research Institute (KAERI). A Semiconductor detectoras a radiation detection sensor with a size of 7 (W) × 6.5 (D) × 2 (H) mm3 was fabricated fromthe CdTe ingot. In addition, the properties of the CdTe sample were observed through four kindsof experiments to analyze its performance. The resistivity was obtained as 1.41 × 1010cm byusing a Keithley 6517A high-precision electrometer. The mobility-lifetime products for electronsand holes were 3.137 × 10−4 cm2/V and 4.868 × 10−5 cm2/V, respectively. Finally, we achieveda 16.8% energy resolution at 59.5 keV for the 241Am gamma-ray source. The CdTe semiconductordetector grown at KAERI has a performance good enough to detect low-energy gamma-rays.
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최효정,김덕현,윤종현,권종범,김문수,김현구,신선경,박선화,Choi, HyoJung,Kim, Deok Hyun,Yoon, JongHyun,Kwon, JongBeom,Kim, Moonsu,Kim, Hyun-Koo,Shin, Sun-Kyoung,Park, Sunhwa 한국지하수토양환경학회 2021 지하수토양환경 Vol.26 No.5
Perfluorinated compounds(PFCs), an emerging environmental pollutant, are environmentally persistent and bioaccumulative organic compounds that possess a toxic impact on human health and ecosystems. PFCs are distributed widely in environment media including groundwater, surface water, soil and sediment. PFCs in contaminated solid can potentially leach into groundwater. Therefore, understanding PFCs partitioning between the aqueous phase and solid phase is important for the determination of their fate and transport in the environment. In this study, the sorption equilibrium batch and kinetic experiment of PFCs were carried out to estimated the sorption coefficient(K<sub>d</sub>) and the fraction between aqueous-solid phase partition, respectively. Sorption branches of the PFDA(Perfluoro-n-decanoic acid), PFNA(Perfluoro-n-nonanoic acid), PFOA(Perfluoro-n-octanoic acid), PFOS(Perfluoro-1-octane sulfonic acid) and PFHxS(Perfluoro-1-hexane sulfonic acid) isotherms were nearly linear, and the estimated K<sub>d</sub> was as follow: PFDA(1.50) > PFOS(1.49) > PFNA(0.81) > PFHxS(0.45) > PFOA(0.39). The sorption kinetics of PFDA, PFNA, PFOA, PFOS and PFHxS onto soil were described by a biexponential adsorption model, suggesting that a fast transport into the surface layer of soil, followed by two-step diffusion transport into the internal water and/or organic matter of soil. Shorter times(<20hr) were required to achieve equilibrium and fraction for adsorption on solid(F<sub>1</sub>, F<sub>2</sub>) increased with perfluorinated carbon chain length and sulfonate compounds in this study. Overall, our results suggested that not only the perfluorocarbon chain length, but also the terminal functional groups are important contributors to electrostatic and hydrophobic interactions between PFCs and soils, and organic matter in soils significantly affects adsorption maximum capacity than kinetic rate.
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응급의학 교육프로그램 경험 전후 응급의학에 대한 의과대학 학생들의 인식 및 태도 변화 분석
최효정,강경원,강영준,류정민,손유동,신상도,윤준성,이동훈,임용수,조한진,최석재,홍기정,김호중 대한응급의학회 2017 대한응급의학회지 Vol.28 No.2
Purpose: This study was performed to analyze the results from a 2016 three-day emergency medicine camp for premedical students. Methods: The Public Relations Committee of Korea Emergency Medical Association planned the camp. We sent an official letter to 41 universities to recruit participants and create programs for three days. Questionnaires were prepared and analyzed before and after the camp. Results: A total of 37 participants participated. There were three times more males than females. According to the recognition survey, knowledge (3.4±2.0 vs. 7.2±1.8) and preference (5.4±1.8 vs. 7.4±1.4) after the camp were better than before the camp (p<0.05). In detail, anxiety about funerals (3.5±2.5 vs. 2.4±2.8) and perception of the role (5.8±2.2 vs. 4.5±2.6) were improved (p<0.05). Worries regarding physical and psychological burden and danger were also greatly improved (p<0.05). The mean satisfaction was 8.6 points out of 10 points, according to the general survey. Conclusion: The three-day camp increased awareness of emergency medicine and improved their preferences.
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