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기흉으로 내원하여 흉관삽관 후 악화된 식도파열 환자 1례
장석빈,고찬영,김용오 대한응급의학회 2024 대한응급의학회지 Vol.35 No.1
Spontaneous rupture of the esophagus wall is a rare, life-threatening condition, and the diagnosis of esophageal rupture is challenging as history and symptoms can be nonspecific. In some cases, chest radiography can reveal pneumothorax. We report a case of aggravated esophageal rupture after chest tube intubation in an esophageal rupture patient with pneumothorax. Interventionists should be aware that esophageal rupture may present as pneumothorax and that chest tube insertion can exacerbate esophageal rupture.
즐례 : 복막전이를 동반한 그물막의 악성 혈관주위 상피모양세포 종양 1예
장석빈 ( Suk Bin Jang ),서원용 ( Won Yong Suh ),전지현 ( Ji Hyun Jeon ),박건우 ( Keon Woo Park ),임도형 ( Do Hyoung Lim ),남궁환 ( Hwan Namgung ),이순일 ( Soon Il Lee ) 대한내과학회 2014 대한내과학회지 Vol.86 No.1
혈관주위 상피모양세포 종양은 조직학적으로 HMB-45에 강한 양성을 보이는 상피 모양세포를 가지는 중간엽 종양의 한 범주를 총칭한다. 대개 양성경과를 보이며 진단 당시 전 이성 병변을 가지는 예는 흔치 않아 수술적 절제술이 일반 적인 치료로 선택된다. 그러나 양성과 악성의 조직학적 명확 한 경계가 없으며 재발에 대한 예측에 제한점이 많아 다양 한 치료 시도들이 지속되고 있다. 저자들은 좌상복부 거대 종괴 소견을 보인 환자를 대상으로 종괴제거 수술을 시행하 였고 복벽에 다수의 파종성 결절을 확인하였으며 절제된 종괴 및 결절조직의 면역 조직화학염색검사에서 HMB-45 강한 양성을 보여 복강으로 전이된 그물막의 악성 혈관주위 상피 모양세포 종양을 확진하였다. 환자는 더 이상의 추가적 치료를 원하지 않았으며 이후 7개월 만에 다발성 전이로 악화된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The World Health Organization (WHO) defines a perivascular epithelioid cell tumor (PEComa) as a mesenchymal neoplasia composed of perivascular epithelioid cells with characteristic morphological and immunohistochemical features. They are rarely malignant. Indeed, only a few cases have been reported in the English literature, and this is the first case of PEComa reported in Korea. A 64-year-old man presented with an abdominal mass and peritoneal seeding. The patient underwent mass excision with descending colon resection and anastomosis. The primary mass and peritoneal seeding was diagnosed as a PEComa histopathologically. Seven months later, he developed liver metastasis and aggravated peritoneal seeding. Here, we report a case of malignant PEComa of the omentum. (Korean J Med 2014;86:96-101)
지역장애인구강진료센터의 역할 및 전담치과위생사의 적정역할에 대한 고찰
고태희,장석빈,이재영,조자원 대한예방치과·구강보건학회 2022 大韓口腔保健學會誌 Vol.46 No.4
Objectives: This study aims to define the role of the local dental clinic for people with disabilities and the appropriate role of the dental hygienist to resolve oral health inequality with people with disabilities. Methods: From September 12, 2022 to November 11, 2022, 16 experts who voluntarily participated in the research, among the experts recommended by the related institutes, were selected through stratification analysis. The results of this study and improvement plans are as follows. Results: First, as a result of measuring the importance of the role of a regional oral care center for people with disabilities in the analytic hierarchy process (AHP) middle category, check-up was found to be the most important (0.364, C.I=0.01). For examination, a facility visit checkup and regular checkups were required. Second, as a result of measuring the importance of the role of a dedicated dental hygienist in the AHP middle category, the institutional-linked activity was found to be the most important (0.417, C.I=0.02). As for institutional-linked activities, linkage with local community organizations, patient management, and public relations activities were required. Conclusions: Considering these results, the role of a regional oral care center for people with disabilities is to perform examinations and preventive treatments, primary treatments (simple), education and counseling, and establish a smooth medical return system to serve as a base for dental treatment for people with disabilities. Education and counseling are provided through professional patient response and the arrangement of a dedicated dental hygienist, and oral health care is provided to people with disabilities through professional treatment assistance for patients and treatment support and screening, linkage with local community institutions, and patient management. Specialized dental hygienists should play a role in supporting the operation of oral health care for people with disabilities.
0.5% 구연산아연 및 1,450 ppm 불소가 함유된 세치제의 구취 예방 효과
김성진,장석빈,이재영,조자원 대한예방치과·구강보건학회 2022 大韓口腔保健學會誌 Vol.46 No.4
Objectives: This study aims to verify the effect of the use of a toothpaste containing 0.5% zinc citrate and 1,450 ppm fluoride on oral malodor. Methods: In this study, the experimental group using the experimental toothpaste and the control group using the standard toothpaste control toothpaste were allowed to use each toothpaste for 4 weeks and then a clinical test to measure the change in bad breath was conducted. A study was conducted to evaluate the reduction effect. Efficacy was evaluated by conducting BB checker test and Oralchroma test three times in total before the testing 2 weeks and 4 weeks after the test. Results: As a result of measuring the degree of bad breath using the BB checker, before the start of the test, the experimental group was 46.3 and the control group was 47.2. After 2 weeks of the test, the experimental group was 38.5 and the control group was 44.2 and after 4 weeks the experimental group was 29.6 and the control group was 39.2. There was a significant difference between the experimental group and the control group after 4 weeks of the test (P<0.05). The volatile sulfur compounds measured by Oralchroma were 0.825 ng/10 ml for the experimental group and 0.819 ng/10 ml for the control group after 2 weeks of the test, and they were 0.705 ng/10 ml for the experimental group and 0.860 ng/10ml for the control group after 4 weeks of the test. It was confirmed that a significant index change appeared after 4 weeks of the test compared to before the test (P<0.05). Conclusions: It was confirmed that an improved effect of removing bad breath can be expected when a toothpaste containing 0.5% zinc citrate and 1,450 ppm fluoride is used.
권혁찬,임도형,최지성,장석빈,박건우,박재석,이순일 대한노인병학회 2014 Annals of geriatric medicine and research Vol.18 No.1
Tuberculous peritonitis is one of the most common extrapulmonary tuberculosis. The presenting signs and symptoms, together with the carbohydrate antigen (CA) 125 status and imaging findings may resemble the primary peritoneal carcinoma or ovarian carcinoma. We herein report a case on a 71-year-old woman who is presented with abdominal distension, abdominal pain, nausea, anorexia. Abdomino-pelvic computed tomography scans reveal large amounts of ascites and mottled omentum with diffuse nodular masses, and the serum CA 125 level is elevated. The initial clinical diagnosis is the primary peritoneal carcinoma, but the final histological diagnosis confirms the tuberculous peritonitis. Thus, we discuss the differential diagnosis of tuberculous peritonitis from primary peritoneal carcinoma and also the problems especially found in old aged patients. In conclusion, although the elderly patients are suspected with malignancy, we should keep in mind the possibility of curable diseases and perform laparoscopic biopsy during the early stage aggressively.
The First Case of Cutaneous Acanthamoebiasis Caused by Acanthamoeba triangularis in Korea
최미수,명나혜,서민,장석빈,윤대관,염규진,정동일,박병철,Yeon-ChulHONG,김명화 대한피부과학회 2023 Annals of Dermatology Vol.35 No.-
A 62-year-old man with multiple myeloma visited our clinic with multiple painful erythem- atous to purpuric nodules on his whole body. He received a skin biopsy which showed septal and lobular inf lammation with vasculitis, and multiple amoebic organisms were found. Polymerase chain reaction and culture were performed and an Acanthamoeba triangularis infection was diagnosed. This is the first report on cutaneous acanthamoebiasis caused by A. triangularis, suggesting that A. triangularis should be regarded as a clinical pathogen that can cause ocular as well as disseminated infection.
김상훈,김상헌,윤호주,지영구,박재석,신동호,이영구,장석빈,박성수,이병훈 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.1
Purpose: Drug-induced liver injury (DILI) is a serious issue often leading to discontinuation of the proper regimen of antituberculosis drugs (ATD). Previous studies have suggested that antioxidant enzymes play an important role in DILI. Methods: We explored whether polymorphisms in superoxide dismutase genes, including Cu/Zn superoxide dismutase (SOD1), manganese superoxide dismutase (SOD2) and extracellular superoxide dismutase (SOD3) are associated with ATD-induced hepatitis. Genotype distributions of four single nucleotide polymorphisms (SNPs) in three genes (rs2070424, SOD1; rs4880, SOD2; rs2536512, and rs1799895, SOD3) were compared between 84 patients with ATD-induced hepatitis and 237 patients tolerant to ATD. Results: Intron SNP rs2070424 of SOD1 showed a significant association with ATD-induced hepatitis. The frequency of genotypes carrying minor alleles (GA or GG) was significantly higher in the case group than that of controls (P=0.019, OR=2.26, 95% CI 1.14-4.49). For the other SNPs of SOD2 and SOD3, there were no differences in genotype frequencies between ATD-induced hepatitis and ATD-tolerant controls. Conclusions: These findings suggest that rs2070424 of SOD1 is significantly associated with ATD-induced hepatitis. This genetic variant may be a risk factor for ATD-induced hepatitis in individuals from Korea.