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이순일,박세훈,임도형,박건우,이지연,박준오,박영석,임호영,강원기 대한암학회 2011 Cancer Research and Treatment Vol.43 No.2
Purpose Fluoropyrimidine-based combination chemotherapy, in combination with either oxaliplatin or irinotecan, has demonstrated efficacy and tolerability in treatment of advanced colorectal cancer (ACC). Materials and Methods Between January 2006 and December 2007, a total of 478 ACC patients were treated with combination chemotherapy in first-line settings. Combination therapies included: 5-fluorouracil,folinic acid plus oxaliplatin (FOLFOX, n=172), 5-fluorouracil, folinic acid plus irinotecan (FOLFIRI, n=95), capecitabine plus oxaliplatin (XELOX, n=155), and capecitabine plus irinotecan (XELIRI, n=56). FOLFOX and FOLFIRI were repeated every 2 weeks, whereas XELOX and XELIRI were repeated every 3 weeks until occurrence of disease progression or unacceptable toxicity, or until a patient chose to discontinue treatment. Results The median age was 58 years (range, 19 to 84 years) and the median chemotherapy durations for FOLFOX, FOLFIRI, XELOX, and XELIRI were 4.9, 4.5, 5.7, and 5.4 months,respectively. Combination chemotherapy regimens were generally well tolerated. The estimated median progression-free-survival (PFS) for all patients was 6.8 months (95%confidence interval, 6.3 to 7.3 months). No statistically significant difference in PFS was found among regimens used as first-line chemotherapy. Sixty percent (n=290) of patients received second or further lines of therapy after failure. Conclusion Fluoropyrimidine-based combination chemotherapy regimens appear to be equally active and tolerable as first-line therapy for ACC.
이순일,유광하,임형래,조화상,송종오 대한신장학회 1996 Kidney Research and Clinical Practice Vol.15 No.1
Emphysematous cystitis is characterized by gas collection within the bladder wall and lumen. Persons with diabetes, neurogenic bladder and chronic urinary infection are predisposed to the disease. Treatment consists of urinary drainage, prompt initiation of antibiotic therapy, and strict glucose control. We report a case of emphysematous cystitis in 54 year old male patient with diabetes mellitus.
Nb를 첨가한 $TiO_2$ 의 전기적 성질 및 결함형태
이순일,백승봉,김명호 한국세라믹학회 1999 한국세라믹학회지 Vol.36 No.12
The electrical conductivity ($\sigma$) of TiO2 doped with 0.05-4.0mol% Nb2O5 was measured in the oxygen partial pressure range of 10-17 to 100 atm and temperature range of 1100 to 130$0^{\circ}C$ to investigate the electrical properties and defect types. The oxygen partial pressure dependence of the electrical conductivity (log$\sigma$/logPo2) above 110$0^{\circ}C$ was divided into the four regions. From these experimental results the following defect regions were proposed ; 1) Magneli phase(extended defect) 2) reduced rutile region where intrinsic defect predominates 3) nearly stoichiometric region which is independent on the oxygen partical pressure and 4) overstoichiometric region which is not observed in pure TiO2 The electrical conductivity of Nb-doped TiO2 depended on the doping content the oxygen partial pressure and the measuring tem-perature.
반복되는 복통으로 진단된 호산구성 위장관염에 동반된 호산구성 복수와 방광염 1예
이순일,박희승,하병길,김동현,유진택,최성호 고신대학교 의과대학 2011 고신대학교 의과대학 학술지 Vol.26 No.2
Eosinophilic gastroenteritis is a relatively uncommondisease of unknown etiology and pathogensis. It is characterized by massive tissue eosinophilia, that can involve any layers of the gastrointestinal tract wall. The gastrointestinal signs and symptoms usually reflect the layer which is most severly affected. Eosinophilic gastroenteritis can be rarely accompanied by extraintestinal involvement. We report a case of a 19-year-old male with repeated epigastric and low abdominal pain. An abdominal computed tomography showed diffused wall thickeningof esophagus, small bowel and bladder with ascites. Esosinophilic infiltration was shown by multiple biopsies of the esophagus, duodenum on esophagogastroduodenoscopy and peritoneal fluid analysis. The patient was diagnosed with eosinophilic gastroenteritis, accompanied by esosinophilic ascites and cystitis and was treated with corticosteroid and ketotifen. Abdominal pain was improved dramatically.
시군통합 읍면지역의 경제력 격차 분석 : 지역소득의 발생을 중심으로
이순배(李順培),하채수(河彩洙) 한국정책과학학회 2009 한국정책과학학회보 Vol.13 No.2
시군통합으로 도농 간의 상호보완과 지역개발을 주민들의 선호와 일치시킴으로서 도시와 농촌지역의 균형적인 발전을 촉진시켜 지역의 경쟁력을 확보하고자 했었다. 이러한 기대효과를 읍면지역의 경제력 격차분석으로 검증해본 결과, 읍면의 재정력이 큰 경기도, 충청남도 및 기타의 일부 읍면지역에서는 격차가 완화된 ,즉 비교적 균형적으로 발전하고 있는 것으로 나타난 반면에 나머지 대부분의 읍면지역에서는 통합시의 중심지(도심지)로의 경제력 및 인구의 집중현상이 지속 내지는 심화되고 있는 것으로 나타났다. 가중된 읍면 점유비율과 지니계수의 연도별 비교?분석에서는 큰 변화는 없었지만 지니계수의 절대적 크기로 보아 읍면지역 간의 경제력 격차는 더욱 심해지는 것으로 나타났다. 2007년도에 경제력이 가장 약한 112개 읍면 중에서 55개 읍면은 그들이 소속된 통합시가 낙후 지역으로 선정되어 중앙정부의 지원을 받는 반면에 나머지 57개 읍면은 그들의 통합시가 낙후지역으로 선정되지 못하여 정부의 재정지원을 받지 못하는 ‘지원의 사각지대’로 남을 가능성이 있다는 것을 보여준다. This study are to analyze from viewpoint of the economic capacity of Eup-Myeon area in the consolidated cities, whether it has been gotten by the city-county consolidation a positive effect such as the balanced growth between urban and rural and their competitiveness. As a result of this analysis, it has been indirectly proved, that the economic disparities between urban and rural area is decreasing relatively in the consolidated cities with strong economic capacity, and increasing in the consolidated cities with small economic capacity.